Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
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| Number | Title | Issue Date |
| 7223335 | Ion separation A device for separating ions from a fluid stream is disclosed. The device includes multiple chambers in fluid communication with one another. A first chamber has an inlet, and a last chamber has an outlet. The inlets and outlets of intermediate chambers are connecte... | 05/29/2007 |
| 7198702 | Method for separating substances using dielectrophoretic forces The present invention has an object of providing a method by which two kinds or more of molecules can be separated each other by using dielectrophoretic forces. The present invention comprises two methods. The first method is a method comprising forming a complex su... | 04/03/2007 |
| 7179374 | Device for shear-thinning of solids containing material The invention relates to a device to be used in connection with thickening and clarifying apparatuses for shear-thinning of solids containing material, such as slurry, which device contains one conduit for feeding material to be shear-thinnned and another conduit fo... | 02/20/2007 |
| 7172694 | Filter assembly The filter assembly is adapted for use in filtering fluid flow in turbomachinery. The filter assembly includes a cylindrical housing, and a filter element disposed within the housing. The housing is adapted for fluid connection to a turbomachine. The filter element ... | 02/06/2007 |
| 7144487 | Factor VIII separation The claims describe methods for isolating functionally active Factor VIII using a membrane-based separation system containing a separation membrane to create a first and second interstitial volume between at least two restriction membranes. One or more stabilizing a... | 12/05/2006 |
| 7033473 | Method and apparatus for combined magnetophoretic and dielectrophoretic manipulation of analyte mixtures Methods and apparatuses for discriminating matter utilizing dielectrophoresis combined with magnetophoresis. A sample having one or more constituents is injected into an inlet port of a chamber. A carrier medium flow is initiated at the inlet port to establish a flo... | 04/25/2006 |
| 7014744 | Method of purification and concentration using AC fields with a transfer tip Embodiments of methods and devices are disclosed for the manipulation (e.g., concentration, purification, capture, trapping, location, transfer, etc.) of analytes, e.g., biomolecules, with respect to analyte-containing solutions using one or more electric fields. | 03/21/2006 |
| 6893878 | Centrifugal spectrometer A centrifugal spectrometer has a solid rotor (10) formed within which there are cavities or blades (12). In use, each blade is filled with a buffer solution, and a sample to be separated is placed in a sample well (32) at the end of a separation... | 05/17/2005 |
| 6403367 | Integrated portable biological detection system We have performed separation of bacterial and cancer cells from peripheral human blood in microfabricated electronic chips by dielectrophoresis. The isolated cells were examined by staining the nuclei with fluorescent dye followed by laser induced fluores... | 06/11/2002 |
| 6277265 | Apparatus and method for electrocoriolysis, the separation of ionic substances from liquids in the electrodynamic mode An apparatus and method for electrocoriolysis, the separation of ionic substances from liquids in the electrodynamic mode. The method maximizes centrifugal forces on a fluid contained in a chamber having oppositely polarized electrodes. A feed fluid is fe... | 08/21/2001 |
| 6054053 | Methods of improving peak resolution in reversed-phase electrochromatography Peak resolution in reversed-phase electrochromatography is improved in either of two alternative ways. The first is by a stepwise increase in the concentration of acetonitrile or other equivalent buffer constituent or modifier after the sample has been lo... | 04/25/2000 |
| 5938930 | Methods of improving peak resolution in reversed-phase electrochromatography Peak resolution in reversed-phase electrochromatography is improved in either of two alternative ways. The first is by a stepwise increase in the concentration of acetonitrile or other equivalent buffer constituent or modifier after the sample has been lo... | 08/17/1999 |
| 5734020 | Production and use of magnetic porous inorganic materials Magnetic porous inorganic siliceous materials having a particle size of about 1 to about 200 microns useful as solid supports in various chromatography, immunoassays, synthesis and other separation and purification procedures is disclosed.... | 03/31/1998 |
| 5476992 | In-situ remediation of contaminated heterogeneous soils A process for the in-situ remediation of a contaminated heterogeneous soil region comprising: (a) introducing material for treating contaminants in a contaminated heterogeneous soil region into at least one liquid permeable region within the contaminated ... | 12/19/1995 |
| 5453382 | Electrochromatographic preconcentration method Solutions of analytes in concentrations too low for certain analytical techniques such as various capillary electrophoresis techniques are concentrated in a solid-phase adsorption medium by a technique which involves a pressure-gradient-driven adsorption ... | 09/26/1995 |
| 5403455 | Apparatus and method for removing liquid from liquid bearing material An apparatus and method for moving at least some of the liquid in liquid bearing soil or ground are provided, the method comprising the steps of disposing a first electrode unit and a second electrode unit in the ground so as to have at least portions the... | 04/04/1995 |
| 5290401 | Method and a device for separating plastic particles from supensions The invention relates to a method for separating plastic particles (P) from a suspension (L), e.g. from a cellulose mass or cellulose pulp suspension, in which the fiber-floc material is broken for loosening the plastic particles (P). In the method, turbu... | 03/01/1994 |
| 5277774 | Free flow electrophoresis method The present invention relates to a free flow electrophoresis method between two ion permeable membranes comprising applying an electric field perpendicular to the primary carrier flow, applying a secondary carrier flow perpendicular to both the primary bu... | 01/11/1994 |
| 5200050 | Electrophoretic processor and methods An electrophoretic processor for separating proteins and other chemicals exhibiting varying electrophoretic mobilities. The preferred processor includes a rotor which turns within a stator to define a processing chamber therebetween. The rotor and stator ... | 04/06/1993 |
| 5122246 | Free flow electrophoresis method The present invention relates to a free flow electrophoresis method between two ion permeable membranes comprising applying an electric field perpendicular to the primary carrier flow, applying a secondary carrier flow perpendicular to both the primary bu... | 06/16/1992 |
| 5082541 | Method and apparatus for continuous electrophoresis A method and apparatus for conducting continuous separation of substances by electrophoresis are disclosed. The process involves electrophoretic separation combined with couette flow in a thin volume defined by opposing surfaces. By alternating the polari... | 01/21/1992 |
| 5049248 | Liquid separation process for suspensions by a pulsating electrical current A method of removing liquid from a suspension by concurrently subjecting the suspension to the action of a pulsed D.C. electrical field and in a second embodiment a concurrent sonic or ultrasonic field so as to remove liquid from the suspension. The suspe... | 09/17/1991 |
| 4994161 | Apparatus and method for macromolecular charge determination A method of (and apparatus for) determining charge on protein or other macromolecule. The method involves providing two spaces, each containing buffer (e.g., water or saltwater), establishing a volume (a cuvette herein) between the two spaces, which volum... | 02/19/1991 |
| 4911806 | Method and apparatus for separating particles in liquid suspension utilizing oscillating electric and magnetic fields Small dielectric particles such as biological cells or DNA molecules are suspended in a quantity of liquid within a container. A pair of spaced apart electrodes are immersed in the liquid and a coil surrounds the region between the electrodes. First and s... | 03/27/1990 |
| 4900421 | Vortex stabilized electrophoretic separation apparatus An apparatus for the performance of efficient, large scale separations, particularly electrophoresis and isoelectric focusing, in free solution is described. Inner and outer cylinders define an annular separation chamber for solutions stabilized against c... | 02/13/1990 |
| 4801366 | Apparatuses and methods for analyzing macro-ions at electrophoretic steady state A stable, unchanging concentration gradient of macro-ions dissolved in aqueous or other polar solvents is established adjacent to a semipermeable membrane by the opposing forces of a directed electric field and diffusion, a condition herein defined as ele... | 01/31/1989 |
| 4767514 | Apparatus and method for removing liquid from liquid bearing material An apparatus and method for removing liquid from liquid bearing material is provided, the apparatus comprising a pair of spaced apart electrodes for being disposed on opposite sides of the material, a unit for creating an electrostatic field between the e... | 08/30/1988 |
| 4726904 | Apparatus and method for the analysis and separation of macroions An apparatus for the separation of macroion groups from a mixture utilizing a three field device for generating forces on the macroions including means for applying a centrifugal force, means for applying a magnetophoretic force, and means for applying a ... | 02/23/1988 |
| 4683042 | Method and apparatus for continuous annular electrochromatography Separation of complex mixtures and solutions can be carried out using a method and apparatus for continuous annular electrochromatography. Solutes are diverted radially by an imposed electrical field as they move downward in a rotating chromatographic col... | 07/28/1987 |
| 4642169 | Continuous rotating electrophoresis column and process of using A continuous rotating annular electrophoresis column for the separation of chemical mixtures. The principle of separation is similar to the conventional electrophoresis; however, it is different in that the electric field is applied in the axial direction... | 02/10/1987 |
| 4465574 | Blood fractionation improvement The extraction of Factor VIII, the antihaemophilic factor in blood, is difficult due to its instability and the presence of impurities. An initial Factor VIII containing aqueous solution such as blood plasma is purified by subjecting a Factor VIII contain... | 08/14/1984 |
| 4432849 | Method and apparatus for separating macromolecules or particles in a liquid solution A solution of macromolecules or other particles suspended therein is subjected to a centrifugal force applied in one direction and simultaneously to a force imposed in a direction opposite to said one direction by an electric field applied, thereby separa... | 02/21/1984 |
| 4250008 | Purification of Factor VIII PCT No. PCT/GB78/00038 Sec. 371 Date June 22, 1979 Sec. 102(e) Date June 22, 1979, PCT Filed Nov. 10, 1978 PCT Pub. No. WO 79/00299 PCT Pub. Date May 31, 1979. The invention is concerned with purification of Factor VIII containing solutions, such as blood... | 02/10/1981 |
| 4246085 | Fractionation of proteins The invention is concerned with fractionation of proteins, in particular with fractionation of immunoglobulin containing solutions, such as blood plasma, by continuous flow electrophoresis. Hitherto, such solutions have been fractionated by ethanol precipitati... | 01/20/1981 |
| 4141809 | Separation process Continuous flow electrophoresis in an apparatus such as described in U.S. Pat. No. 3,616,453 is stabilized by using a migrant solution containing a sufficient quantity of a liquid of density less than water such as ethanol. Continuous flow electrophoresis... | 02/27/1979 |
| 4116789 | Clarifier and method A fluid, such as air or water, carrying suspended solids is directed between a pair of oppositely charged, corrugated surfaces in order to subject the flow to an undulating action that increases the frequency with which the solid particles impinge against... | 09/26/1978 |
| 4104142 | Suspended solids extraction system and method A liquid containing suspended solids is first passed through an electrostatic treater, having no current flow across its electrodes, to initiate nucleation and coagulation of the particles. Thereafter, it passes through an electrolytic treater wherein cur... | 08/01/1978 |
| 4017390 | Method for separating solid pollutants from fluids Treatment of fluid polluted with solid particles, for instance, from a dust removal or washing process, by pretreating the fluid to agglomerate the particles, then whirling the fluid to centrifugally concentrate the particles in a first fraction of the fl... | 04/12/1977 |
| 4008135 | Method of deionizing solutions A method of deionizing a solution in which the solution is accelerated through a passage which has alternating narrow and wide portions. One side of the passage is maintained at a higher electrical potential than the other side and the ions migrating to o... | 02/15/1977 |
| 3970536 | Liquid treating method and apparatus A filter method and apparatus removes tramp oils and fine particulate contaminants from an electrically conductive liquid coolant which is utilized in metal forming, or other comparable, operations. The disclosed method includes flowing the liquid coolant... | 07/20/1976 |