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Class 204/466 - Using slab gel


Subclass of Class 204 - Chemistry: electrical and wave energy
Definition: Process in which the gel is planar in form (e.g., as a rectangular
No. of patents: 190
Last issue date: 05/29/2012


1          
NumberTitleIssue Date
8187438Use of an electrophoretic gel provided with a non-adherent polymer film
This invention relates to electrophoresis, in particular pre-cast mini gels with a low fluorescent polymer backing that is not adherent to the gel. Use of this type of small gel simplifies blotting procedures, such as Southern and Western blotting, after electrophor...
05/29/2012
8034223Methods and apparatus for low resistance electrophoresis of prior-cast, hydratable separation media
Methods and apparatus are presented that facilitate electrophoresis of prior-cast, hydratable separation media, usefully immobilized pH gradient (IPG) strips. The method exploits the swelling of prior-cast, hydratable separation media upon rehydration to help lodge ...
10/11/2011
7578917Magnetic locking mechanism for gel electrophoresis device
An electrode arrangement for a gel electrophoresis device, the electrode arrangement comprising a first electrode member adapted to provide an electrical contact with one or more gel strips, wherein the first electrode member comprises a first locking element to loc...
08/25/2009
7452453System for pH-neutral stable electrophoresis gel
A gel and buffer system for gel electrophoresis wherein separation occurs at neutral pH. ...
11/18/2008
7422670System for pH-neutral stable electrophoresis gel
A gel and buffer system for gel electrophoresis wherein separation occurs at neutral pH. ...
09/09/2008
7384781Sensors for biomolecular detection and cell classification
A sensor device is provided for detecting an analyte in a sample in which an analyte is bound to a detection reagent to form a bound complex. The device comprises (a) a sample (5) comprising an ionic analyte and a detection reagent in a conductive fluid, wher...
06/10/2008
7384525Electrophoretic analysis system having in-situ calibration
An electrophoretic system having a plurality of separation lanes is provided with an automatic calibration feature in which each lane is separately calibrated. For each lane, the calibration coefficients map a spectrum of received channel intensities onto values ref...
06/10/2008
7374649Dispersion of carbon nanotubes by nucleic acids
Carbon nanotubes dispersed by a stabilized solution of nucleic acid molecules formed separated nanotube-nucleic acid complexes and were separated according to standard chromatographic methods, including gel electrophoresis, two phase solvent systems and ion exchange...
05/20/2008
7323092Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis
While the present invention has been described in conjunction with a preferred embodiment, one of ordinary skill, after reading the foregoing specification, will be able to effect various changes, substitutions of equivalents, and other alterations to the compositio...
01/29/2008
7320747Gel for electrophoresis
The present invention is directed to a solidified hybrid gel for use in an electrophoresis process, having a solidified first gel portion juxtaposed with a solidified second gel portion. The first gel portion is capable of accommodating therein one or more samples f...
01/22/2008
7309409Multi-channel bio-separation cartridge
A bio-separation system using an efficient, compact, portable, interchangeable, reusable, recyclable, multi-channel cartridge, has integrated pre-aligned optics and an integrated reagent reservoir. The cartridge supports, for example, multiple capillaries for CE sep...
12/18/2007
7282126System and method for determining known DNA variants with temperature gradient electrophoresis
The present invention relates to a method of determining the genotype of a sample polynucleotide having at least a first variant site. At least a portion of the sample polynucleotide is amplified to obtain first amplicons, the first amplicons including the first var...
10/16/2007
7276143Electrophoresis module having electrophoresis bath with upright carriers
The electrophoresis module has an upright cassette of which at least one of the front and rear sides has a recess opened upwardly, the recess has on the peripheral edge thereof a buffering member; the cassette has on the two ends thereof a clamping assembly each, ea...
10/02/2007
7250100Two dimensional electrophoresis cassette
A device for two-dimensional electrophoresis includes a cassette comprising two opposing plates. The two opposing plates form a first elongated portion for receiving a first elongated electrophoretic separation medium and a second portion extending away from the fir...
07/31/2007
7229539Destructible surfactants and uses thereof
Destructible surfactants and methods of using same are provided. The invention includes anionic surfactants having a dioxolane or dioxane functional group which enables the surfactant to be broken down under acidic conditions. The invention also includes methods of ...
06/12/2007
7189316Pulsed field electrophoresis chambers, accessories and method of utilization for separation of DNA molecules
Methods of use, accessories and chambers, optimal for performing Pulsed Field Gel Electrophoresis (PFGE) of DNA molecules in ‘Contour Clamped Homogeneous Electric Field’ (CHEF) and ‘Transversal Alternating Field Electrophoresis’ (TAFE) systems, are provided ...
03/13/2007
7153403Protein market pellets and method of making and using the same
A protein marker pellet for use in a gel electrophoresis system includes one or more protein markers including a protein of known molecular weight with ionic components to provide electrical conductance, and a non-protein, gel-forming material having a porosity suff...
12/26/2006
7153405Cassette, system, and 2-D gel electrophoresis method for separating molecules
A gel electrophoresis cassette (33) is disclosed which includes two plates (34, 35) and at least one seal (36) which separates these plates. The seal (36) is annular; it may be positioned essentially in the region of the outer edge of the...
12/26/2006
7144487Factor VIII separation
The claims describe methods for isolating functionally active Factor VIII using a membrane-based separation system containing a separation membrane to create a first and second interstitial volume between at least two restriction membranes. One or more stabilizing a...
12/05/2006
7141153pK-matched running buffers for gel electrophoresis
pK-matched buffers, each containing two effective buffering components: one weak base and one weak acid which have similar pKa at 25° C. (within 0.3 pK units). On agarose gels, the buffers in various concentrations were tested for separation of double-st...
11/28/2006
7122104Electrophoresis apparatus for simultaneous loading of multiple samples
The present invention includes apparatus for simultaneous loading of multiple samples for molecular separation, including a separation area with walls wherein at least one of the walls has apertures having loading sites, a gel located within the separation area, and...
10/17/2006
7077940Strip holder, chamber, cassette, and 2-D gel electrophoresis method and system for performing this method for separating molecules
A strip holder (1) is disclosed for accommodating a gel strip (3) for separating molecules using gel electrophoresis. The strip holder (1) disclosed is distinguished by including a baseplate (4), at least one stop (5), which is off...
07/18/2006
7074312Device for stacking multiple pre-cast horizontal gels
A device for vertically stacking multiple pre-cast gels for simultaneous electrophoresis is described. The device comprises a plate of non-electrically conductive material that separates adjacent gels within a vertical stack and facilitates contact between the ends ...
07/11/2006
7074367Thermostated block with heat-regulating devices
The invention concerns a thermostated block for laboratory thermostats and comprising wells at a wells side to receive and make large-area contact with the parts of vials filled with sample liquids and comprising at least two heat regulating devices contacting the t...
07/11/2006
7033477Electrophoresis gel assembly
A thin-film electrophoresis assembly includes a support frame having a top portion and a substantially flat face, a first thin-film member carried by the support frame, a second thin-film member carried by the support frame, and a resolving gel sandwiched between th...
04/25/2006
6986836Electrophoresis gels with incorporated indicia
An electrophoresis gel is prepared with indicia incorporated into the gel itself rather than on a label or backing that is adhered to the gel. According to one method, the indicia are applied by first coating a solid surface that will be used as one internal surface...
01/17/2006
6942774Electrophoresis apparatus and a method of using the same
An apparatus for rehydrating and for performing electrophoresis on a gel strip includes a tray defining a plurality of parallel troughs configured to receive gel strips. Each trough defines a centrally located rehydration area and an electrode area disposed either s...
09/13/2005
6942775Vertical electrophoresis system
A plugging medium is used to block the bottom opening of cassettes for vertical electrophoresis in order to facilitate filling the cassettes with separation media. Cassettes can be filled within a vertical electrophoresis system in which electrophoresis is conducted...
09/13/2005
6939453Electrophoresis process using ionic liquids
Highly hydrophobic compounds and hydrophobic proteins are solubilized in a non-aqueous solvent containing an electrolyte for electrophoretic separation. The non-aqueous solvent is an ionic liquid or a mixture of an organic solvent containing an ionic liquid in an am...
09/06/2005
6936150Methods and apparatus for electrophoresis of prior-cast, hydratable separation media
Methods and apparatus are presented that facilitate electrophoresis of prior-cast, hydratable separation media, usefully immobilized pH gradient (IPG) strips. The method exploits the swelling of prior-cast, hydratable separation media upon rehydration to help lodge ...
08/30/2005
6929730Two dimensional microfluidic gene scanner
One embodiment of the invention relates to a microfluidic apparatus for performing two dimensional biomolecular separations. According to one aspect of the invention, after a first dimension separation in a first microchannel, the sample material is electrokinetical...
08/16/2005
6905105Apparatus for preparing a biocompatible matrix
An apparatus and method of using the apparatus to prepare a biocompatible biodegradable matrix capable of supporting cells to form an implantable or engraftable surgical device. A matrix-forming fluid is contained within a chamber defined by top and bottom surfaces ...
06/14/2005
6905585Automated system for high-throughput electrophoretic separations
A cassette is disclosed for use in performing electrophoretic separations on a solid substrate. The cassette includes reservoirs for containing buffer, electrodes for receiving electrical current and a substrate support. The cassette is designed to connect with exte...
06/14/2005
6841055Method of preparing electrophoretic support, electrophoretic matrix, and method of electrophoresis
A method of preparing an electrophoretic support comprising washing of at least a portion of the surface of a silicon-containing support member supporting an electrophoretic matrix with a weak alkali solution and supporting of said matrix by said support member; an ...
01/11/2005
6833060Electrophoresis gel support
The present invention relates generally to the electrophoretic separation of biomolecules, including but not limited to proteins, peptides, DNA and RNA. The methods of this invention are particularly useful when applied to two-dimensional gel electrophoresis. ...
12/21/2004
6821402Spectral calibration of fluorescent polynucleotide separation apparatus
The invention relates to methods, compositions, and systems for calibrating a fluorescent polynucleotide separation apparatus. One aspect of the invention is multiple color calibration standards and their use. A multiple color calibration standard is a mixture of at...
11/23/2004
6793790Sample collection system for gel electrophoresis
An automatic sample collection system for use with an electrophoretic slab gel system is presented. The collection system can be used with a slab gel have one or more lanes. A detector is used to detect particle bands on the slab gel within a detection zone. Such de...
09/21/2004
6783648Method and apparatus for unloading gels from isoelectric gel tubes
An apparatus for expressing and unloading an isoelectric focusing gel from an electrophoresis gel tube includes a first support for supporting the gel tube, a plunger rod and a second support for supporting the plunger rod. The first support is mounted on a movable ...
08/31/2004
6682641Electrophoresis assembly and method of casting electrophoresis gels
The invention provides an electrophoresis cassette to cast electrophoresis gels and to separate and analyze molecular components by electrophoresis. The electrophoresis cassette comprises a top plate assembly, a spacer and a bottom plate. The top plate as...
01/27/2004
6652724Automated apparatus for separating a biological sample from a two dimensional electrophoresis gel
An automated high-throughput system for excising spots or samples from an electrophoresis slab gel includes a computer controlled robotic arm assembly and a sample plate handling assembly for supplying a sample plate to a loading station. The computer is ...
11/25/2003
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