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| Number | Title | Issue Date |
| 5466348 | Methods and devices for enhanced biochemical sensing A method and application for detecting and measuring the presence of a binding target material employs a semiconductor device having a receptor-covered surface topgate, separated by a dielectric layer from a substrate. Receptors attached to this surface e... | 11/14/1995 |
| 5464516 | Process for producing an electrophoresis separation layer An electrophoresis separation layer is produced which comprises a polyacrylamide gel which remains stable even when stored for a long time and is available for analyzing substances of an extremely wide molecular weight range in electrophoresis for determi... | 11/07/1995 |
| 5451303 | Cleaning hydrophilic contact lenses by electrochemical means A composition and method for cleaning and disinfecting of contact lenses that employ an electrical field applied to a lens that causes contaminating deposits to migrate therefrom is described. The composition of the invention includes a pair of component ... | 09/19/1995 |
| 5427663 | Microlithographic array for macromolecule and cell fractionation A sorting apparatus and method for fractionating and simultaneously viewing individual microstructures, such as free cells, viruses, macromolecules, or minute particles in a fluid medium. The sorting apparatus is composed of a substrate having a receptacl... | 06/27/1995 |
| 5308459 | Biosynthetic cerebrospinal fluid control and method of use The present invention relates to a biosynthetic cerebrospinal fluid control and method of use. Additionally, this invention relates to the isolation and purification of stable liquid human prealbumin, a component in the biosynthetic cerebrospinal fluid co... | 05/03/1994 |
| 5302510 | DNA sizing control standards for electrophoretic analyses The present invention is directed to a method for assessing the reliability of DNA sizing measurements performed on DNA samples. DNA sizing control standards are disclosed wherein each standard contains a unique set of DNA restriction fragments composed o... | 04/12/1994 |
| 5298135 | Production of electrophoretically-homogenous protein-colloidal gold complexes A method is provided to determine the conditions required for the production of homogeneous protein-colloidal gold complexes. The method uses the electrophoretic migration of a discrete fraction of a sample of protein-colloidal gold complexes to identify,... | 03/29/1994 |
| 5284558 | Electrophoresis-based sequencing of oligosaccharides The electrophoretic isolation and monosaccharide sequence determination of a neutral or weakly acidic oligosaccharide species of interest are disclosed. A labeling compound and a charged group are coupled to the reducing end of the species of interest, th... | 02/08/1994 |
| 5233030 | High molecular weight DNA compositions for use in electrophoresis of large nucleic acids The invention provides high molecular weight DNA length standards useful for sizing very long DNA molecules and methods for producing such standards. In a preferred embodiment, the invention provides a mixture of T4 DNA concatemers that forms a DNA "ladde... | 08/03/1993 |
| 5196099 | Electrophoretic matrix and electrophoresis using same An electrophoretic matrix comprised of at least one water-insolubilized, temperature-responsive polymeric compound having an LCST is disclosed. The electro-phoretic matrix can change its hydrophilic/hydrophobic property by changing temperature. A method o... | 03/23/1993 |
| 5190856 | Method and apparatus for detecting single base mutations in DNA with denaturing gradient electrophoresis Single base pair differences between otherwise identical DNA fragments can result in an altering of the melting behavior which can be detected by denaturing gradient gelelectrophoresis (DGGE). A method has been developed for efficient transfer of genomic ... | 03/02/1993 |
| 5164057 | Electrophoretic matrices and electrophoretic method using same An electrophoretic matrix comprised of at least one water-insolubilized, temperature-responsive polymeric compound having an LCST is disclosed. The electrophoretic matrix can change its hydrophilic/hydrophobic property by changing temperature. A method of... | 11/17/1992 |
| 5159049 | Method for stabilizing polyacrylamide gels A method for preparing stabilized, rehydratable polyacrylamide gels, wherein the stabilizers employed include substituted monosaccharides where the hydroxyl group of the carbon 1 is substituted with a non-charged group comprising an -methyl group o... | 10/27/1992 |
| 5149416 | Polymeric electrophoresis media Preformed, water-soluble, acrylamide based copolymers comprising a minor proportion of a comonomer, which comonomer contains a site for a crosslinking reaction with a selected crosslinking agent by a reaction that does not involve a free-radical vinyl add... | 09/22/1992 |
| 5124247 | Process for sequencing nucleic acids For the sequencing of nucleic acids by enzymatic extension of an oligonucleotide primer in the presence of a polymerase, the four deoxyribonucleoside triphosphates, one of the four dideoxynucleoside triphosphates and the nucleic acid to be sequenced as te... | 06/23/1992 |
| 5100778 | Oligosaccharide sequencing A method of oligosaccharide sequencing in which the components are determined essentially simultaneously is disclosed which comprises a series of steps as follows: A. Placing an identifying label on the reducing terminal residue of the oligosaccharide to ... | 03/31/1992 |
| 5068019 | Electrophoresis film support An electrophoresis film support particularly useful for the electrophoretic separation of serum proteins. According to one aspect, the electrophoresis film support comprises a microporous polymer membrane sheet containing therein an additive which is sele... | 11/26/1991 |
| 5057438 | Electrophoretic antigen-antibody determination with laminate of multiple membranes Determination of a plurality of species of antibodies or antigens is attained by a method which comprises forming a plurality of different kinds of reaction membranes each having a different species of antibody or antigen on an electrophoretic carrier, su... | 10/15/1991 |
| 4966792 | Method of producing gradient gel medium membrane for electrophoresis A method for producing gradient gel medium membrane for electrophoresis for determining the base sequence of DNA or DNA partially decomposed material providing an improved productivity. High and low concentration monomer solutions are mixed with a predete... | 10/30/1990 |
| 4849077 | Process for solid phase-sequencing of nucleic acid fragments A process for solid phase sequencing of nucleic acid fragments is disclosed. The object of the invention is to provide a sequencing process which enables the simultaneous sequencing of large amounts of long and short nucleic acid fragments and which is op... | 07/18/1989 |
| 4771384 | System and method for fragmentation mapping A system and method for the construction of one-dimensional maps from fragmentation data is disclosed. Particularly useful for construction of restriction maps of DNA, the system and method completely permutes sites, single digest fragments, and any avail... | 09/13/1988 |
| 4746551 | Rehydratable polyacrylamide gels The present invention relates to rehydratable polyacrylamide gels. The rehydratable gels can be stored at room temperature for long periods of time and rehydrated with various materials to provide a suitable matrix for various electrophoretic separations.... | 05/24/1988 |
| 4707236 | Method of farbricating an optically graded light occluding gel The invention pertains to an electrophoretic technique for fabricating a progressively graded concentration of dye in a hydrophilic polymeric matrix or gel. A charged dye or dye precursor is caused to migrate under the influence of an electrical potential... | 11/17/1987 |
| 4661451 | Methods for immobilizing and translocating biological cells Apparatus for immobilizing biological cells based on the dielectric properties of biological cells. An inhomogeneous electric field emanating from a grid point location or other contact area is created and attracts the biological cell into contact therewi... | 04/28/1987 |
| 4609707 | Synthesis of polymers containing integral antibodies A method is disclosed for the de novo synthesis of antibody-containing polymers and the preparation of a class of polymerizable compounds used in the synthesis of such antibody-containing polymers. Antibody-containing polymers formed from monomer/antibody... | 09/02/1986 |
| 4541910 | Method for electroblotting macromolecules from a chromatographic gel An improved method of electroblotting macromolecules from a chromatographic gel is claimed. The method comprises a design for wire electrode arrays that are capable of generating either highly uniform or controlled predetermined gradient electric fields. ... | 09/17/1985 |
| 4298441 | Method of preserving the electrophoretic properties of lipoproteins A method of preserving the electrophoretic properties of lipoproteins in human or animal plasma, plasma fractions or sera, in which the lipoprotein pattern is to be electrophoretically determined, consists in that non-reducing sugars are added to the plas... | 11/03/1981 |
| 4290911 | Agarose composition, aqueous gel and method of making same A finely-divided solid blend of (1) purified agarose having an electroendosmosis value (-Mr) below 0.10 with (2) a water-soluble gum which by itself is soluble in boiling water without gelling, free from charged groups and from electroendosmosis, and solu... | 09/22/1981 |
| 4200508 | Method and composition for detecting antigenic substances A method and composition for detecting an antigenic substance by immunodiffusion using an antigenic substance to be detected labeled by a chromogenic enzyme. According to the method and the detection material of this invention, even a small amount of an a... | 04/29/1980 |
| 4146454 | Electromolecular propulsion in diverse semiconductive media This application is directed to an electromotive process for exciting a chemical species which includes orientating, re-positioning and transporting and for the separation of chemical species on a support. Unlike conventional semiconductive technology in ... | 03/27/1979 |
| 4006069 | Support for electrophoretic analysis A support for use in electrophoretic analysis comprising a porous polymeric flat plate such as filter paper, cellulose acetate or a non-woven fabric and a polymeric gel, such as polyacrylamide gel, enclosed in the open cells of the flat plate. The gel mem... | 02/01/1977 |
| 3984298 | Electromolecular propulsion in semiconductive media This application is directed to a high-voltage electromotive process to excite a chemical species, which includes orientating, re-positioning and transporting and for the separation of chemical species on a support. Unlike conventional semiconductive tech... | 10/05/1976 |
| 3975162 | Applying reagent to medium and device therefor Device for applying a measured quantity of water-soluble or water-dispersible reagent to a water-containing solid medium for use in molecular diffusion or affinity separation procedures is provided in the form of a film consisting essentially of a film-fo... | 08/17/1976 |
