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| Number | Title | Issue Date |
| 7699052 | Apparatus for the dispensing of liquids, container cartridge suitable for this, and system comprising the apparatus for the dispensing of liquids, and the container cartridge The present invention relates to a propellant-gas-free apparatus for the dispensing of liquids, a container cartridge suitable for this for storing the liquid and the ensemble comprising both. The invention comprises a device for the exertion of pressure and for acc... | 04/20/2010 |
| 7461649 | Portable gas operating inhaler An inhaler comprising a compressed gas, such as Heliox gas is provided. The disclosed inhaler includes a first chamber containing a compressed gas which is in communication with an equalization chamber having pressure lower than the pressure of the gas in the first ... | 12/09/2008 |
| 7404400 | Spacer device for inhaler A spacer device for an inhaler is made of a non-metallic antistatic material, preferably polyamide. The device may comprise two frustoconical members joined at their wider ends, with an inlet and outlet at, respectively, the two narrower ends. A measured dose of med... | 07/29/2008 |
| 7360536 | Devices and methods for nebulizing fluids for inhalation A nebulizer comprising an aerosol generator and a titration mechanism comprising a dosing mechanism, a screw assembly, a plunger and an actuator, wherein the dosing mechanism is rotatably mounted in the nebulizer and the plunger is mounted in the nebulizer to travel... | 04/22/2008 |
| 7351232 | Nasal rinser and outlet portion therefor An outlet portion for nasal rinsers includes an outlet end, a connection end and a nozzle shaped channel, showing a restriction and an expanded outlet, in between. ... | 04/01/2008 |
| 7342660 | Detection system and method for aerosol delivery An apparatus comprises a detector, a pressure sensor and a processor. The detector is operable to detect light that is scattered by an aerosol that is associated with a pressure. The pressure sensor is operable to measure the pressure. The processor is coupled to th... | 03/11/2008 |
| 7334580 | Methods, devices and formulations for targeted endobronchial therapy The present invention provides an improved method and novel devices for treating tracheobronchitis, bronchiectasis and pneumonia in the intubated patient, preferably with aerosolized anti gram-positive and anti-gram negative antibiotics administered in combination o... | 02/26/2008 |
| 7318434 | Synthetic jet based medicament delivery method and apparatus A dry powder inhaler consisting of first chamber having an orifice for holding a dry powder and a gas, and a second chamber for receiving a deaggregated form of the dry powder and for communicating the deaggregated dry powder to a user. A synthetic jet drives the dr... | 01/15/2008 |
| 7302948 | Fluid dispensing device A fluid dispensing device comprising a body defining a cavity and a dispensing nozzle. A fluid discharging device is housed in the cavity. The fluid discharging device has a hollow casing defining a reservoir for containing a volume of fluid and a plunger slidingly ... | 12/04/2007 |
| 7296566 | Nasal delivery device including spray nozzle A nasal delivery device is provided for delivering substances such as liquid drugs, vaccines and the like to a nasal passage. The nasal delivery device preferably comprises a drug container such as syringe and a separable spray nozzle. The spray nozzle includes a ri... | 11/20/2007 |
| 7293559 | Device and method for creating aerosols for drug delivery A drug delivery device and method is disclosed which produces aerosolized particles of pharmaceutically active drug for delivery to a patient by inhalation. The device is comprised of a liquid feeding source such as a channel to which formulation is added at one end... | 11/13/2007 |
| 7290543 | Fluid product dispensing device A fluid dispenser device having a body (1), a fluid reservoir (3) containing two half-doses, a dispensing mechanism that dispenses a half-dose of fluid upon actuation, and an energy accumulation mechanism (50, 51, 55) that accumulates energy in ... | 11/06/2007 |
| 7278426 | Securing dose quality of an inhalable drug A method and a device for making a metered dry powder medication dose, enclosed in a dose container, accessible for inhalation with a minimum of exposure to ambient atmosphere. ... | 10/09/2007 |
| 7270127 | Medicament respiratory delivery device A medicament respiratory delivery device including a housing formed of opposed thermoformed polymeric sheets bonded together having formed therebetween a chamber having a medicament cartridge encapsulated between the sheets, an inlet aligned with a passage through t... | 09/18/2007 |
| RE39847 | Method of treating a systemic disease A method of treating a systemic disease in a patient in need of such treatment is disclosed. The method comprising maintaining the inspiratory flow rate and volume of the patient to a certain value and then administering a medicament aerosol formulation to such pati... | 09/18/2007 |
| 7258119 | Dispenser A dispensing apparatus for dispensing a unit dose of a pharmaceutical substance, in particular for intranasal administration, is described. The apparatus includes a nozzle unit having a safety cap thereon and an actuating device. The safety cap has legs, which can l... | 08/21/2007 |
| 7246617 | Inhalers An inhaler comprises a pump 17, a drug dosing device 15 and a cyclone 1 which delivers an aerosol of powdered medicament from the drug dosing device 15 into a chamber 11 when the pump 17 is activated. The aerosol is inhaled ... | 07/24/2007 |
| 7246615 | Atomising nozzle and filter and spray generating device A nozzle assembly for use in atomizing and generating sprays from a fluid. The nozzle assembly includes two members, each with generally planar surfaces, that are joined together. A first set of channels is formed in the generally planar surface of a first one of th... | 07/24/2007 |
| 7244714 | Methods of delivering aerosolized polynucleotides to the respiratory tract Methods and devices for delivering aerosolized formulations containing polynucleotides to specified regions within a subject's respiratory tract are disclosed. The methods find use in the delivery of ribozymes, antisense polynucleotides, and DNA and RNA expression v... | 07/17/2007 |
| 7237549 | Device for distributing a fluid of the single dose or half dose type A fluid dispenser device including a body (1), a reservoir unit (3) having a reservoir containing one dose or two half-doses of fluid, a dispensing member mounted to move axially inside the reservoir (3) between a rest position and a dispensing ... | 07/03/2007 |
| 7225808 | Inhalation device An inhalation device is described for use with a medicament pack in which at least one container for medicament in powder form is defined between two sheets peelably secured to one another. The device comprises means for peeling the sheets apart at an opening statio... | 06/05/2007 |
| 7204822 | Intranasal delivery system This invention relates to apparatus and methods of delivering various compositions including medicaments to a variety of targets. The invention includes a dose administrator (1) which may be used for intranasal delivery of compositions or medicaments, such as... | 04/17/2007 |
| 7201164 | Aerosol medication delivery apparatus with narrow orifice An aerosol medication delivery apparatus includes a holding chamber having an input end and an output end and defining an interior space. The output end comprises an orifice having a cross-sectional area of less than about 60 mm2. In one preferred embodim... | 04/10/2007 |
| 7195011 | Convertible fluid feed system with comformable reservoir and methods A feed system for an aerosolizer utilizes an ampoule containing a liquid and includes a housing having an ampoule region into which the ampoule is held, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule. An interface is used ... | 03/27/2007 |
| 7185647 | Determination of smoothness of canisters containing inhalable medicaments Disclosed are methods for determining the smoothness index of the interior of a metered dose container. ... | 03/06/2007 |
| 7175053 | Laterally-actuated fluid dispenser device A fluid dispenser device having a fluid reservoir (10), a pump (20) mounted on the reservoir (10) for selectively dispensing the fluid, and a dispenser head (30) connected to the pump and incorporating a dispenser orifice (31). The... | 02/13/2007 |
| 7173222 | Aerosol generator having temperature controlled heating zone and method of use thereof A temperature and flow rate controlled capillary aerosol generator includes two heating zones optionally separated by a region in which a pressure drop is induced. Power is metered or applied to the downstream, second zone to achieve a target resistance, and therefo... | 02/06/2007 |
| 7166280 | Combination growth factor therapy and cell therapy for treatment of acute and chronic heart disease Acute and chronic heart disease is treated using a rational, multi-tier approach. A patient is pretreated with growth factor proteins or gene therapy, followed by the administration of adult stem cells. The progress of treatment is continuously monitored by echo-car... | 01/23/2007 |
| 7163013 | Apparatus for the nasal or oral delivery of a medicament An apparatus (1) for the nasal or oral delivery of a medicament, comprises: (a) a sealed flexible container (3) containing the medicament and a gaseous propellant for the medicament; and (b) a delivery device (5), comprising: (i) a main body par... | 01/16/2007 |
| 7153823 | Methods of use of fibroblast growth factor, vascular endothelial growth factor and related proteins in the treatment of acute and chronic heart disease Disclosed herein is a rational, multi-tier approach to the administration of growth factor proteins in the treatment of heart disease. Also disclosed is a method to evaluate the effectiveness of the administration of growth factor proteins comprising the clinical as... | 12/26/2006 |
| 7146977 | Valve system and method for aerosol delivery An apparatus comprises a variable acoustic source and a microphone, both acoustically coupled to a volume having a fluid region and an air region. The apparatus also can include a processor to determine a volume of the air region based on signals received from the m... | 12/12/2006 |
| 7117867 | Aerosol generator and methods of making and using an aerosol generator An aerosol generator includes a flow passage having an inlet and an outlet, a heater arranged relative to the flow passage for heating the flow passage, a source of material to be volatilized in communication with the inlet of the flow passage, a valve to open and c... | 10/10/2006 |
| 7118227 | Projection display device An illuminating optical system for focusing a radiant light of a light source (1) onto a reflecting light valve (6) and a projection lens (7) for magnifying and projecting a reflected light from the reflecting light valve (6) onto a scree... | 10/10/2006 |
| 7118010 | Apparatus, systems and related methods for dispensing and /or evaluating dry powders Methods, systems, and computer program products flowably dispense meted amounts of dry powders using a flexing piezoelectric layer to transmit a vibratory signal to the dry powder to facilitate fluidic flow through a flow channel. The apparatus for dispensing dry po... | 10/10/2006 |
| 7108159 | Fluid dispenser device of the multi-dose type A fluid dispenser device a body (1), a fluid reservoir (3), a dispensing member, such as a pump or a metering valve having a piston or a valve member that is mounted to move axially, which dispensing member is fitted to the reservoir (3), and an... | 09/19/2006 |
| 7107987 | Spacer for delivery of medications from an inhaler to children and breathing impaired patients A spacer for delivering a medication spray from an inhaler includes a first conical body joined to a second conical body, forming a continuous spray conduit through first and second internal chambers of the respective first and second conical bodies. A mouthpiece is... | 09/19/2006 |
| 7089940 | Balanced valve device and breathing apparatus comprising such valve device A valve device, particularly for a breathing regulator for divers, including an inlet chamber which can be connected to a source of gas under super-atmospheric pressure, and an outlet chamber which is under a regulated pressure. A seating, which is movable under the... | 08/15/2006 |
| 7091179 | Methods of use of fibroblast growth factor, vascular endothelial growth factor and related proteins in the treatment of acute and chronic heart disease Disclosed herein is a rational, multi-tier approach to the administration of growth factor proteins in the treatment of heart disease. Also disclosed is a method to evaluate the effectiveness of the administration of growth factor proteins comprising the clinical as... | 08/15/2006 |
| 7077125 | Apparatus for administering aerosols A stationary inhalation apparatus for the individual controlled inhalation of therapeutic aerosols comprises a drug-release means 3, at least one drug reservoir 2, a reader 4 for reading out a patient's individual parameters and/or the aerosol p... | 07/18/2006 |
| 7073499 | Inhaler with airflow regulation The present invention is generally directed to a respiratory delivery system (e.g. an inhaler) used to discharge an appropriate substance therefrom for inhalation by a user. The respiratory delivery system generally has at least one airflow inlet, at least one outle... | 07/11/2006 |