Bizarre Patents
Wearable Device For Feeding and Observing Birds and Other Flying Animals
A device for feeding and observing flying animals comprising a hat, a support mounted on the hat and extending outward from the hat, and a feeder mounted on the support.
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| Application No. | Application Title | Issue Date |
| 20120131687 | AGENT THAT MODULATES PHYSIOLOGICAL CONDITION OF PESTS, INVOLVED IN INSECT VOLTAGE-GATED POTASSIUM CHANNEL ACTIVITY The present invention provides an agent that modulates physiological condition of pests, wherein the agent has an ability to modulate the activity of an insect voltage-gated potassium channel; a method for assaying pesticidal activity of a test substance, which comprise... | 05/24/2012 |
| 20120129869 | PHOSPHORYLATION AND MUTATIONS OF ANAPLASTIC LYMPHOMA KINASE AS A DIAGNOSTIC AND THERAPEUTIC TARGET IN LUNG CANCER The invention related to the use of high-density loss of heterozygosity (LOH) mapping in lung adenocarcinoma to identify intragenic LOH and driver mutations in different domains of ALK resulted in enhanced tumor growth in xenografted mouse. Mutant (H694R and E1384K) ALK... | 05/24/2012 |
| 20120110682 | Animal Model for Toxicology and Dose Prediction The invention relates to the use of fetal tissues to generate a tissue model in a non-human animal. The tissue model comprises target tissues allowed to progress through development in vivo in a non-human host in order to obtain tissues having a mature phenotype that ca... | 05/03/2012 |
| 20120070444 | IN VIVO SCREENING MODELS FOR TREATMENT OF isoQC-RELATED DISORDERS A transgenic non-human animal for overexpressing isoQC, comprising cells containing a DNA transgene encoding human isoQC, characterized in that said human isoQC comprises the amino acid sequence of SEQ ID NO: 1 or an amino acid sequence having at least 75% sequence iden... | 03/22/2012 |
| 20120073001 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS The invention features therapeutic compositions comprising agents useful for the treatment or prevention of pruritis, and methods useful for identifying such agents.... | 03/22/2012 |
| 20120054878 | METHOD AND SYSTEM FOR ANALYZING OPTICAL SIGNAL The present invention is related to a method of analyzing an optical signal which analyzes a signal substance induced by a photosensitive protein, includes the steps of introducing a gene which expresses a luminescent probe to analyze the signal substance into an organi... | 03/01/2012 |
| 20120042398 | COMPOSITIONS FOR LABELING AND IDENTIFYING AUTOPHAGOSOMES AND METHODS FOR MAKING AND USING THEM The invention provides methods and compositions for detecting and measuring the amount of autophagosomes in cells or tissues, including biopsy samples, in vitro, in situ and/or in vivo. By detecting and measuring the amount of autophagosomes in cells or tissues, the met... | 02/16/2012 |
| 20120036588 | METHOD FOR OBSERVING GAD67-POSITIVE CELL IN TRANSGENIC ANIMAL A method for observing glutamate decarboxylase 67-positive cells in a transgenic mouse includes providing the transgenic mouse in which a nucleic acid sequence encoding green fluorescent protein is inserted in a frame within exon 1 of an endogenous glutamate decarboxyla... | 02/09/2012 |
| 20120036587 | PROSTATE CANCER CELL LINES AND THEIR USE IN SCREENING METHOD The present invention relates to a prostate cancer cell line CNCM deposit number I-4126, the use thereof for preparing resistant prostate cancer cell lines, the resistant prostate cancer cell lines, and the use of these prostate cancer cell lines for screening compounds... | 02/09/2012 |
| 20120030776 | NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO69122, PRO204, PRO214, PRO222, PRO234, P... | 02/02/2012 |
| 20120030778 | GENOMIC EDITING OF GENES INVOLVED WITH PARKINSONS DISEASE The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with Parkinson's disease. In particular, the animals or cells are generated using a zinc finger nuclease-mediated editing process. ... | 02/02/2012 |
| 20120030777 | METHODS FOR TESTING FOR CALORIC RESTRICTION (CR) MIMETICS Methods for treating neurological diseases and for testing Caloric Restriction (CR) mimetics or CR mimetic candidates. In one exemplary method, a CR mimetic candidate is administered to a transgenic animal and the effects of the administering are determined; the transge... | 02/02/2012 |
| 20120023599 | GENOME EDITING OF CYTOCHROME P450 IN ANIMALS The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding cytochrome P450 (CYP) proteins. In particular, the animals or cells are generated using a zinc finger nuclease-mediated editing process. The invention ... | 01/26/2012 |
| 20120014975 | MODIFIED SINGLE DOMAIN ANTIGEN BINDING MOLECULES AND USES THEREOF The invention relates to modified single domain antigen binding molecules, e.g., SDAB molecules, in particular TNFα-binding SDAB molecules. Method of preparing, and using the modified single domain antigen binding molecules described herein, to treat, e.g., TNFα-assoc... | 01/19/2012 |
| 20120005766 | Methods of identifying agents that modulate phenotypes related to disruptions, of a gene encoding PRO235 polypeptide The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO188, PRO235, PRO266, PRO337, PRO361, PRO... | 01/05/2012 |
| 20120005765 | ANIMAL MODEL FOR PARKINSON'S DISEASE Disclosed are methods and compositions for an animal model of Parkinson's disease. In particular, disclosed is the use of antisense compounds to inhibit the expression of ALDH1A1 in the substantia nigra of an animal brain for the purpose of creating an animal that will ... | 01/05/2012 |
| 20110321179 | NON-HUMAN ANIMAL MODEL FOR AMYOTROPHIC LATERAL SCLEROSIS (ALS) WITH LOSS-OF-TDP-43 FUNCTION A non-human animal model for amyotrophic lateral sclerosis (ALS) is disclosed. The animal model comprises a rodent whose spinal cord motor neurons have a loss of TAR-DNA binding protein-43 (TDP-43) function and phenotypes exhibit ALS-like symptoms. A method for identify... | 12/29/2011 |
| 20110296540 | ASSAY FOR SCREENING ANTIDEPRESSANTS This invention provides a method for identifying a small molecule as an antidepressant, a method for identifying a small molecule as an anxiolytic, and a method for identifying a small molecule as able to increase dendritic arborization, decrease expression of an immatu... | 12/01/2011 |
| 20110296538 | IN VIVO QUANTITATIVE SCREENING TEST FOR ANTI-METASTASIS TREATMENT EFFICACY The present invention is directed to methods for evaluating the efficacy of a cancer treatment for (i) inhibiting metastasis in a subject, (ii) inhibiting local cancer cell movement, and (iii) inhibiting cancer cell proliferation. The present invention is further direct... | 12/01/2011 |
| 20110296539 | Mutant Alpha-Synuclein, and Methods Using Same The present invention relates to a mutant human alpha-synuclein with increased toxicity compared to wild-type alpha-synuclein, or a homologue thereof, wherein the mutant alpha-synuclein or homologue thereof comprises at least one amino acid substitution selected from th... | 12/01/2011 |
| 20110288027 | TARGETS, METHODS, AND REAGENTS FOR DIAGNOSIS AND TREATMENT OF SCHIZOPHRENIA The present invention provides targets, methods, and reagents for the diagnosis and treatment of schizophrenia and related conditions. The invention provides methods for the diagnosis of schizophrenia and susceptibility to schizophrenia by detection of polymorphisms, mu... | 11/24/2011 |
| 20110286990 | METHODS OF DIAGNOSING AND TREATING FIBROSIS The present invention is directed to methods of diagnosing and treating a fibrotic condition in a mammalian subject. These methods involve measuring the levels of trimethylation at lysine residue 27 of histone-3 and/or measuring the expression levels of EZH2 or YY-1. Ag... | 11/24/2011 |
| 20110289604 | Methods for Identifying Modulating Compounds of Lymphangiogenesis, Means Therefore, Compounds and Uses Thereof The invention relates to a method for testing whether a compound is capable of inhibiting the development of lymphatic channels or lymphangiogenesis and/or the migration of lymphangioblasts in an non-human animal, a non-human embryo or a cell culture, comprising steps o... | 11/24/2011 |
| 20110289605 | Animal Model for Osteoarthritis and Intervertebral Disc Disease Provided herein is a transgenic animal whose genome comprises a first nucleic acid sequence encoding a fusion polypeptide, wherein the fusion polypeptide comprises a Cre recombinase and a mutated ligand binding domain of human estrogen receptor (CreER), wherein the firs... | 11/24/2011 |
| 20110283370 | MOUSE MODEL FOR DEPRESSION, SCHIZOPHRENIA AND ALZHEIMER'S DISEASE AND THE USE THEREOF The present invention relates to Glycine N-methyltransferase (GNMT) animal model and use thereof.... | 11/17/2011 |
| 20110268747 | STXBP1 AS PSYCHIATRIC BIOMARKER IN MURINE MODEL SYSTEM AND THEIR USES A non-human transgenic animal having a polynucleotide encoding an STXBP1 polypeptide, which polynucleotide is operably linked to a promoter, wherein said transgenic animal has greater than wild-type expression of the STXBP1 polypeptide in at least one brain region, as w... | 11/03/2011 |
| 20110263691 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF Non-human animals which overexpress PPARd or which express transgenic PPARd are useful as models for inflammatory skin conditions such as psoriasis. Test substances can be screened to assess their suitability for the treatment of inflammatory skin conditions such as pso... | 10/27/2011 |
| 20110265192 | NUCLEAR RECEPTOR SENSOR SYSTEM IN TRANSGENIC ANIMAL A sensor system for detecting the activation of specific nuclear receptors in a tissue of an animal is provided. The nuclear receptor sensor system comprises a sensor component comprising a nuclear receptor or part thereof coupled to a DNA-binding domain, and a reporter... | 10/27/2011 |
| 20110252485 | Novel gene disruptions, compositions and methods relating thereto The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO844, PRO1131 or PRO5992 genes. Such in v... | 10/13/2011 |
| 20110243854 | Methods and systems for identifying modulators of longevity Methods of treating disorders such as neurofibromatosis-1 are provided, including methods in which catalytic antioxidants such as metalloporphyrins are administered. Methods of regulating longevity, and methods and systems for screening for modulators of aging or longev... | 10/06/2011 |
| 20110247087 | Regulation of endogenous gene expression in cells using zinc finger proteins The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.... | 10/06/2011 |
| 20110239312 | METHODS OF DIAGNOSING AND TREATING MOTOR NEURON DISEASES Use of an agent which upregulates an activity or amount of miRNA-9 or miRNA-9* is disclosed for the preparation of a medicament for the treatment of a motor neuron disease (MND).... | 09/29/2011 |
| 20110236427 | Antagonists of NR2F6 For Augmenting The Immune Response The present invention relates to antagonists/inhibitors of NR2F6 (nuclear orphan receptor receptor Ear2) for the treatment of a disease related to an insufficient immune response. Furthermore, pharmaceutical compositions comprising said antagonists/inhibitors of NR2F6 a... | 09/29/2011 |
| 20110239310 | TRANSGENIC FISH AND USES THEREOF The present invention relates to a transgenic fish having at least one genomically integrated expression cassette containing a 5′-regulatory nucleotide sequence responsive to hormones, particularly estrogenic hormones, connected in a functional manner upstream of a nu... | 09/29/2011 |
| 20110239311 | Agonists of NR2F6 For Immunosupression The present invention relates to agonists/activators of NR2F6 (nuclear orphan receptor receptor Ear2) for the treatment of a disease related to an augmented immune response. Furthermore, pharmaceutical compositions comprising said agonists/activators of NR2F6 and a phar... | 09/29/2011 |
| 20110219462 | G-Protein Coupled Receptor 30 (GPR30) transgenic animals as a model for cardiovascular diseases The present invention relates to use of the GPR30 gene for diagnosis and treatment of cardiovascular disorders, especially cardiomyopathy. The present invention also relates to a GPR30 deficient animal model, more specifically to a mouse in which the GPR30 gene is disru... | 09/08/2011 |
| 20110219463 | METHODS OF SCREENING AGENTS FOR ACTIVITY USING TELEOSTS The present invention provides methods of screening an agent for activity using teleosts. Methods of screening an agent for angiogenesis activity, toxic activity and an effect cell death activity in teleosts are provided. Methods of screening an agent for an activity in... | 09/08/2011 |
| 20110214189 | G PROTEIN COUPLED RECEPTORS AND USES THEREOF The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and... | 09/01/2011 |
| 20110214190 | TRANSGENIC REPORTER MOUSE AND METHOD FOR USE A transgenic mammal, including a transgenic mouse, whose genome comprises a transgene, said transgene comprises a neutrophil gelatinase-associated lipocalin (NGAL) promoter gene operably linked to at least one sequence encoding at least one of a fluorescent or biolumine... | 09/01/2011 |
| 20110214191 | METHOD FOR THE IDENTIFICATION OF GENES INVOLVED IN NEURODEGENERATIVE PROCESSES A method for the identification of genes involved in neurodegenerative processes, detectable by the late onset of a phenotype associated with neurodegeneration, by means of a genetic screen of deregulated genes, which comprises the measurement of sleep-wake cycle activi... | 09/01/2011 |
