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| Application No. | Application Title | Issue Date |
| 20120129188 | CIRCULATING CYTOCHROME C AS BIOMARKER OF REPERFUSION INJURY AND RESPONSIVENESS TO MITOCHONDRIAL TARGETED INTERVENTIONS The present invention relates generally to the use of circulating cytochrome c as a biomarker of reperfusion injury that results from whole body ischemia. Circulating levels of cytochrome c can be used as predictor of survival rates and to assess the effects of interven... | 05/24/2012 |
| 20120082569 | Very-Small-Capacity Pressure Gauge A pressure gauge mounted to a pump or a back pressure regulator in an HPLC, SFC, or SFE system provides improved solvent exchange and improved measurement precision. A through hole having an inside diameter of 1.0 mm is made in a hexagonal member similar in shape to a p... | 04/05/2012 |
| 20120071340 | BIOMARKERS The invention relates to a method of diagnosing or monitoring major depressive disorder.... | 03/22/2012 |
| 20120070825 | Novel Compounds and Derivatizations of DNAs and RNAs on the Nucleobases of Pyrimidines for Function, Structure and Therapeutics Disclosed are compounds of formula (I), a derivative, or a tautomer thereof, or a pharmaceutically acceptable salt of said compound or said tautomer. Also disclosed are methods of preparing compound of formula (I), a derivative, or a tautomer thereof, or a pharmaceutica... | 03/22/2012 |
| 20120071339 | BIOMARKERS The invention relates to a method of diagnosing or monitoring multiple sclerosis.... | 03/22/2012 |
| 20120048003 | VITAMIN ASSAY METHODS A method for performing an assay of at least one target vitamin in an oral care product includes: a) preparing a first analyte comprising a standard solution of the target vitamin to be assayed; b) preparing a second analyte comprising a sample solution derived from the... | 03/01/2012 |
| 20120037507 | METHOD AND MARKER FOR DIAGNOSIS OF TUBULAR KIDNEY DAMAGE AND ILLNESSES A method for the diagnosis of tubular kidney diseases comprising the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, the polypeptide marker being selected from the markers characterized in Table 1 by valu... | 02/16/2012 |
| 20120028280 | XANTHURENIC ACID DERIVATIVE PHARMACEUTICAL COMPOSITIONS AND METHODS RELATED THERETO The present invention relates to diuretic pharmaceutical compositions and methods and in particular to certain derivatives of the formula I:
| |
| 20120015443 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES Chiral selectors having α-unsubstituted β-amino acid derivatives of the structure: a stationary phase for separating substance mixtures containing the chiral selector, and processes for separating mixtures ... | 01/19/2012 |
| 20110302997 | LIQUID CHROMATOGRAPH APPARATUS A liquid chromatograph apparatus capable of eliminating a deviation of measurement results originating from an instrumental error is provided. According to the present invention, a mobile phase arrival time T of the liquid chromatograph app... | 12/15/2011 |
| 20110297543 | Autosomal-Dominant Polycystic Kidney Disease (ADPKD) The process for the diagnosis, early detection and prognosis of the clinical development of autosomal-dominant polycystic kidney disease (ADPKD) comprises the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sampl... | 12/08/2011 |
| 20110290999 | MONOLITHIC COLUMN CHROMATOGRAPHY Provided herein are methods of liquid column chromatography in which preparative chromatography is performed in-line with analytical chromatography. In particular aspects a monolithic preparative column is used to purify an analyte of interest from a mixture of other su... | 12/01/2011 |
| 20110294121 | METHODS AND COMPOSITIONS FOR PROGNOSING, DETECTING, AND TREATING AGE-RELATED MACULAR DEGENERATION The invention provides methods and compositions for determining whether a subject is at risk of developing age-related macular degeneration, for example, the wet or neovascular form of age-related macular degeneration. The method involves determining whether the subject... | 12/01/2011 |
| 20110294735 | MECHANISM OF NEUROMEDIN U ACTION AND USES THEREOF The use of neuromedin U receptor agonists to elevate the levels of GLP-1 and/or PYY in an individual in need of an increase in its levels of GLP-1 and/or PYY is described. Further described is the use of neuromedin U receptor agonists to lower the levels of glucagon in ... | 12/01/2011 |
| 20110294874 | DIAGNOSIS AND THERAPY OF ORGAN DYSFUNCTION USING SPHINGANINE-1-PHOSPHATE The invention relates to the treatment and diagnosis of organ dysfunction caused by ischemia reperfusion injury. In particular, the invention relates to sphinganine-1-phosphate, a sphingolipid metabolite, and its use in the diagnosing, preventing, and/or treating ischem... | 12/01/2011 |
| 20110271755 | Apparatus And Methods For The Measurement Of Mass Related Parameters Embodiments of the present invention are directed to resonating detection devices in which the sample flows through a conduit having a section in which the conduit is grouped or concentrated with the point of maximum movement.... | 11/10/2011 |
| 20110273708 | ULTRASENSITIVE DETECTION OF ISOTOPES, CHEMICAL SUBSTANCES AND BIOLOGICAL SUBSTANCES USING LASER WAVE MIXING DETECTORS Devices and techniques for using four wave mixing in optical sensing of various materials, including isotopes, chemical and biological substances.... | 11/10/2011 |
| 20110269139 | BIOMARKERS AND METHODS FOR DETERMINING SENSITIVITY TO EPIDERMAL GROWTH FACTOR RECEPTOR MODULATORS The present invention provides methods useful for predicting the likelihood that a mammal that will respond therapeutically to a method of treating cancer comprising administering an EGFR modulator, and diagnostic methods and kits thereof.... | 11/03/2011 |
| 20110269241 | Methods And Kits For The Determining The Presence Or Absence Of Cyanobacteria Toxins Embodiments of the present invention are directed to kits and methods for the detection of toxins produced by cyanobacteria. The methods and kits feature sample preparation steps with weak cationic and anionic exchange resins and small particle analytical columns operat... | 11/03/2011 |
| 20110263853 | HPLC METHOD FOR THE ANALYSIS OF BOSETAN AND RELATED SUBSTANCES AND USE OF THESE SUBSTANCES AS REFERENCE STANDARDS AND MARKERS The present invention relates to a new HPLC method for the analysis of the drug substance bosentan and related substances and to the use of said substances as reference standards and markers.... | 10/27/2011 |
| 20110259089 | Devices Having An Inert Surface And Methods Of Making Same The present invention features devices and methods of making such devices for performing liquid chromatography having at least one wetted surface having a composition of a polysilazane.... | 10/27/2011 |
| 20110256063 | MEX3C REGULATION AND TARGET TO CONTROL OBESITY AND DIABETES MEX3C deficiency impairs the development of white and brown adipose tissue. Hence the present invention provides, among other things, a method of screening a candidate compound for activity in inhibiting fat deposition in a subject in need thereof and/or treating a cond... | 10/20/2011 |
| 20110256169 | NOVEL POLYPEPTIDES RELATED TO B-TYPE NATRIURETIC PEPTIDES AND METHODS OF THEIR IDENTIFICATION AND USE The invention provides novel fragments of proBNP and NTproBNP, particularly useful in prognosing or diagnosing acute heart failure, chronic heart failure or sepsis.... | 10/20/2011 |
| 20110245461 | METHODS FOR DETERMINING THE RETENTION OF PEPTIDES IN REVERSE PHASE CHROMATOGRAPHY USING LINEAR SOLVENT STRENGTH THEORY The present disclosure relates to methods for separating or isolating a peptide using reverse phase chromatography. The disclosure also relates to methods for calculating or determining the slope S of a peptide, wherein S is defined according to the Linear-Solvent-Stren... | 10/06/2011 |
| 20110237513 | LTBP2 AS A BIOMARKER FOR RENAL DYSFUNCTION The application discloses LTBP2 as a new biomarker for renal dysfunction; methods for predicting, diagnosing, prognosticating and/or monitoring said dysfunction based on measuring said biomarker; and kits and devices for measuring said biomarker and/or performing said m... | 09/29/2011 |
| 20110236995 | METHOD FOR DETERMINING PROSTATE CANCER The present invention provides a method for detecting a glycan structure of a prostate specific antigen (PSA) rapidly and with high sensitivity and determining prostate carcinoma based on the difference in the structure, in particular, a method for determining between p... | 09/29/2011 |
| 20110229983 | MARKING FUEL FOR AUTHENTICATION A first fuel and a second fuel are marked with a marker that can be detected quantitatively in a predetermined concentration range. The second fuel is marked with a binary marker. Decreased concentration of the quantitative marker, presence of a binary marker, or both m... | 09/22/2011 |
| 20110230453 | Use of Female Mammal's Urine for Determination of Fetal Gender Related Characteristics The present invention provides a method for determining the gender of a fetus by assaying the sex hormones, evaluating the overall reducing/oxidizing (redox) activity, and/or evaluating the radical scavenging capacity of the maternal urine or other body fluid. The metho... | 09/22/2011 |
| 20110220500 | Glucuronidated Acetaminophen as a Marker of Hepatic Disorders The present invention provides methods for diagnosing human hepatic disorders, such as non-alcoholic steatohepatitis (NASH), identifying a human subject at risk of an adverse drug reaction, and determining an appropriate dosage of a therapeutic drug for a human subject.... | 09/15/2011 |
| 20110219858 | COMPOSITION FOR USE AS A PEPTIDE RETENTION STANDARD AND A METHOD OF PREDICTING PEPTIDE HYDROPHOBICITY IN LIQUID CHROMATOGRAPHY A composition comprising synthetic peptides for use as a peptide retention standard in liquid chromatography applications is disclosed Said synthetic peptides have a broad range of hydrophobicity while maintaining low variation in their molecular weights The synthetic p... | 09/15/2011 |
| 20110214990 | KIDNEY CELL CARCINOMA The process for the diagnosis of a renal cell carcinoma comprises the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, wherein said polypeptide markers are selected from the markers as characterized in Tab... | 09/08/2011 |
| 20110212536 | METHOD AND APPARATUS FOR THE ISOTOPE-RATIO ANALYSIS A process and to an apparatus for isotope ratio analysis having the steps of: performing an LC process and thus providing a first eluate which comprises at least one first liquid carrier fluid and one or more analytes, collecting a portion of interest from the eluate, p... | 09/01/2011 |
| 20110212847 | COMPOSITIONS AND METHODS RELATING TO MONITORING ALCOHOL CONSUMPTION AND ALCOHOL ABUSE Methods and compositions according to embodiments of the present invention are provided that specifically and sensitively detect alcohol consumption and whether alcohol consumption is moderate or high in a subject. Aspects of the present invention relate to assays of pa... | 09/01/2011 |
| 20110209766 | Method Transfer Between Fluidic Devices Considering Deviations from Ideal Behavior An apparatus (200) for deriving an operation mode from a first fluidic device to a second fluidic device, wherein the first fluidic device has a first target operation mode (300) representing a desired behavior of the first fluidic device and has a first r... | 09/01/2011 |
| 20110203352 | METHOD AND DEVICE FOR DIRECT QUANTITATIVE DETERMINATION OF PESTICIDE SEED LOADING ON INDIVIDUAL SEEDS The present invention provides methods and devices for the direct quantitative analysis of multiple pesticides on individual seeds with or without fluorescent pigments. The seed varieties include corn, cotton, wheat, soybean and canola.... | 08/25/2011 |
| 20110207919 | EVALUATING HEPARIN PREPARATIONS Methods of evaluating heparin preparations, e.g., for suitability for use as a drug or for use in making a drug, by determining the absence, presence or amount of a structural signature that is indicative of the methods used to make the heparin preparation.... | 08/25/2011 |
| 20110207164 | Method for Assessment of Folate Phenotypes, Disease Risk and Response to Therapy The invention provides a method for measuring the levels of 5-methyltetrahydrofolate (5-MTHF), tetrahydrofolate (THF), and 5,10-MTHF in a biological sample. The method includes employing an isotope dilution liquid chromatography-multiple reaction monitoring/mass spectro... | 08/25/2011 |
| 20110201128 | BLOOD MARKERS OF TRANSPLANTED INTESTINE REJECTION The present invention relates to a method for detecting bowel transplant rejection. The detection method according to the invention is a method for the in vitro detection of bowel transplant rejection comprising steps for measuring the conc... | 08/18/2011 |
| 20110195970 | Methods of identifying and treating responders to dopamine agonist therapy The present invention is directed to a method of identifying patients to be treated by dopamine agonist therapy comprising the step of analyzing a plasma or urine sample from said patient for concentrations of norepinephrine (NE), norepinephrine metabolites (NE metaboli... | 08/11/2011 |
| 20110195971 | Methods of identifying responders to dopamine agonist therapy The present invention is directed to a method of identifying patients to be treated by dopamine agonist therapy comprising the step of analyzing a plasma or urine sample from said patient for concentrations of norepinephrine (NE), norepinephrine metabolites (NE metaboli... | 08/11/2011 |
