...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Application No. | Application Title | Issue Date |
| 20120071966 | DRUG-RELEASING STENT WITH CERAMIC-CONTAINING LAYER A vascular or endoluminal stent is adapted to be implanted in a vessel, duct or tract of a human body to maintain an open lumen. The stent includes a base layer of a biologically compatible metal. An intermediate metal particle layer of substantial greater radiopacity o... | 03/22/2012 |
| 20110153004 | POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY A method of forming a coating on a medical device having a controlled morphology is described. A method of treating a disorder in a patient using the medical device is described.... | 06/23/2011 |
| 20110137404 | INFLATABLE POROUS IMPLANTS AND METHODS FOR DRUG DELIVERY The present invention provides inflatable porous implants, such as grafts, stent-grafts, and bladders, as well as methods and kits for drug delivery. In particular, the grafts and stent-grafts of the present invention provide for the delivery of a therapeutic agent into... | 06/09/2011 |
| 20100303896 | 5BETA, 14BETA-ANDROSTANE DERIVATIVES USEFUL FOR THE TREATMENT OF RESTENOSIS AFTER ANGIOPLASTIC OR ENDOARTHERECTOMY AND DISEASES DUE TO ORGAN FIBROSIS Compound of formula (I), wherein the symbol have the meaning reported in the text; for preparing a medicament for the prevention and/or treatment of obstructive vascular lesions following vascular surgery and for the prevention and/or treatment of diseases due to organ ... | 12/02/2010 |
| 20100234934 | Balloon Deployable Coronary Stent A system for treating a vascular condition includes a delivery catheter, a balloon disposed at a distal end of the delivery catheter, a stent having a stent framework, the stent disposed on an outer surface of the balloon; and at least one restraining filament attached ... | 09/16/2010 |
| 20100150913 | ORGANIC COMPOUNDS The present invention relates to compounds and compositions useful for inhibiting and/or reducing platelet deposition, adhesion and/or aggregation. The present invention also relates to methods for screening compounds and compositions useful for inhibiting or reducing p... | 06/17/2010 |
| 20100082096 | Tailored Luminal & Abluminal Drug Elution A stent has a plurality of members made from a first material. At least one of the plurality of members defines at least one hole. Each hole extends from a first surface of a member. Each hole has a first opening and a depth. Each hole has a barrier dividing the hole in... | 04/01/2010 |
| 20100070022 | LAYER BY LAYER MANUFACTURING OF A STENT A stent is provided which has a relatively less porous support structure that includes a first set of consolidated particles and at least one relatively more porous reservoir that includes a second set of consolidated particles that differ in composition from the first ... | 03/18/2010 |
| 20100047315 | Stent for Increasing Blood Flow to Ischemic Tissues and a Method of Using the Same Stents and a method of using the stents to increase blood flow to ischemic tissues in a patient are disclosed.... | 02/25/2010 |
| 20100030325 | BLOOD ANTICOAGULANT MATERIAL, COATING MATERIAL AND INDWELLING DEVICE COMPRISING THE SAME, AND TREATMENT USING BLOOD ANTICOAGULANT MATERIAL A blood anticoagulant material is provided which has high expandability, reduced influence on living bodies, and can efficiently prevent blood coagulation. A multiblock copolymer having at least a structural unit represented by Formula (1),... | 02/04/2010 |
| 20090326638 | MEDICAL DEVICES FOR DELIVERY OF THERAPEUTIC AGENT IN CONJUNCTION WITH GALVANIC CORROSION According to an aspect of the present invention, at least one ionic therapeutic agent is delivered from an implantable or insertable medical device that comprises an ion-conductive polymeric region that is disposed on a metallic region. The metallic region is in electri... | 12/31/2009 |
| 20090171453 | Drug Coated Stent Having a Surface Treatment and Method of Manufacturing Drug coated stents for implantation in a body vessel are provided. A stent can include a plasma treatment on the luminal surface and a protein-adherence deterring layer on at least a portion of the luminal surface. A further embodiment includes a method of manufacturing... | 07/02/2009 |
| 20090157172 | STENTS WITH POLYMER-FREE COATINGS FOR DELIVERING A THERAPEUTIC AGENT Described herein are implantable medical devices, such as intravascular stents, for delivering therapeutic agents to a patient, and methods for making such medical devices. The medical devices comprise a substrate having at least a cavity therein and a pellet disposed i... | 06/18/2009 |
| 20090143853 | AXIALLY-RADIALLY NESTED EXPANDABLE DEVICE Expandable medical implants for maintaining support of a body lumen are disclosed. These implants comprise an axially-radially nested, diametrically expandable, moveable vascular device for enlarging an occluded portion of a vessel. The device can be configured to allow... | 06/04/2009 |
| 20090125101 | POLYMERIC MATERIALS FOR MEDICAL DEVICES The present invention includes biocompatible polymeric coatings, membranes, matrices, and films to be used with implantable medical devices. Medical devices containing such materials applied to a surface thereof contain a film-forming fluorous homo-polymer or copolymer ... | 05/14/2009 |
| 20090110713 | Biodegradable polymeric materials providing controlled release of hydrophobic drugs from implantable devices The present invention is directed to polymeric materials (e.g., coatings) comprising biodegradable copolymers and implantable devices (e.g., drug-delivery stents) formed of such materials. The biodegradable copolymers are derived from at least two relatively polar monom... | 04/30/2009 |
| 20090088831 | STENT AND STENT DELIVERY DEVICE An stent includes an outer stent base layer formed from a metallic material, an inner stent base layer formed from a metallic material and positioned inside the outer stent base layer, and a resinous adhesive layer containing a biodegradable polymer which is placed betw... | 04/02/2009 |
| 20090076587 | Stented Vascular Graft A vascular graft incorporating a stent into a portion of its length. While various materials may be used for the vascular graft, the graft is preferably an ePTFE graft. The stent is preferably a self-expanding stent, although it may alternatively be a balloon expandable... | 03/19/2009 |
| 20090076595 | Medical devices having bioerodable layers for the release of therapeutic agents According to an aspect of the present invention, medical devices are provided which comprise: (a) a substrate and (b) bioerodable polymeric layer over the substrate that contains (i) one or more biodegradable polymers, (ii) one or more therapeutic agents, and (iii) one ... | 03/19/2009 |
| 20090048667 | Controlled Drug-Release Composition and Drug-Releasable Medical Device A drug-releasable medical device contains a controlled drug-release composition comprising 100 parts by weight of an organic polymeric material which is soluble in an organic solvent and insoluble in water, 5 to 60 parts by weight of a lipid-soluble, low molecular weigh... | 02/19/2009 |
| 20090024200 | Drug Eluting Medical Device and Method A drug elution stent includes a stent framework and a drug elution portion disposed on the stent framework. The drug elution portion includes a first sugar layer disposed on the stent framework, at least one therapeutic agent layer disposed on the first sugar layer and ... | 01/22/2009 |
| 20090018646 | Coating Employing an Anti-Thrombotic Conjugate A biodegradable antithrombotic conjugate having heparin and other anti-thrombotic moieties are introduced as side chains to the polymer backbone modified by click chemistry. Various bioabsorbable monomers and dimers such as valerolactone may be used in the monomer deriv... | 01/15/2009 |
| 20090012595 | Therapeutic Drug-Eluting Endoluminal Covering The present invention is of methods of preventing restenosis and promoting vascular re-healing. Specifically, the present invention is of a method of exposing the luminal wall of a blood vessel to a substance by deploying a drug-eluting polymer film inside the lumen of ... | 01/08/2009 |
| 20090012606 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS This disclosure provides a method device and a method of forming the medical device. The medical device comprises a coating comprising a polymer. The polymer comprises at least two different blocks, at least one L1 block with the formula <... | 01/08/2009 |
| 20080319528 | MODULAR ENDOPROSTHESIS WITH FLEXIBLE INTERCONNECTORS BETWEEN MODULES A modular endoprosthesis is configured to have improved flexibility during and after deployment by having separate endoprosthetic modules that are interconnected by flexible interconnectors. The modular endoprosthesis includes a plurality of separate endoprosthetic modu... | 12/25/2008 |
| 20080311173 | IMPLANTABLE OR INSERTABLE MEDICAL DEVICES FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT The present invention is directed to novel implantable or insertable medical devices that provide release of a therapeutic agent. According to a first aspect of the present invention, a therapeutic-agent-releasing medical device is provided, which comprises: (a) an impl... | 12/18/2008 |
| 20080294242 | EXPANDABLE MEDICAL DEVICE WITH DUCTILE HINGES An expandable tissue supporting device of the present invention employs ductile hinges at selected points in the expandable device. When expansion forces are applied to the device as a whole, the ductile hinges concentrate expansion stresses and strains in small well de... | 11/27/2008 |
| 20080288059 | Stent Drug Delivery System Expandable intraluminal stents are provided as well their method of manufacture. These stents are made of metal, the metal characterized by a desired porosity, with a drug compressed into the pores of the stent. The stents are formed by subjecting one or more powdered m... | 11/20/2008 |
| 20080269875 | Coating for a Medical Device Having an Anti-Thrombotic Conjugate Methods for making comb-type antithrombotic conjugate wherein substantially all side chains of water soluble poly(vinyl alcohol) (PVA) are extended by ring-opening polymerization to form a copolymer wherein substantially all terminals are conjugated to an antithrombotic... | 10/30/2008 |
| 20080262589 | Intravascular Implant The invention has for its object the provision of an intravascular implant that has mechanical characteristics and physiological characteristics and is very low in cell cytotoxicity and provides an intravascular implant having an implant body made of a metal material th... | 10/23/2008 |
| 20080255659 | Fabrication method for drug-eluting stent with medicine-compatible loading mechanisms A MEMS-based fabrication process is disclosed to fabricate a hollow seamless drug-eluting stent. This stent fabrication process is characterized by using a photolithography process, a composite electroplating process, and a polishing process to mass-produce drug-eluting... | 10/16/2008 |
| 20080255657 | STENT WITH UNCONNECTED STENT SEGMENTS This invention generally relates to stents, such as intravascular stents. More particularly, the invention is directed to stents comprising expandable stent segments, such as unconnected expandable stent segments. The invention is also directed to methods for making suc... | 10/16/2008 |
| 20080242922 | HYBRID HEMODIALYSIS ACCESS GRAFTS OR A HYBRID FEMORAL ARTERY BYPASS GRAFT AND SYSTEMS AND METHODS FOR PRODUCING OR MODIFYING THE SAME Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments of systems can include a pressure/flow loop subsystem having an external fl... | 10/02/2008 |
| 20080242921 | SYSTEMS AND METHODS OF PROMOTING ENGRAFTMENT OF A HYBRID HEMODIALYSIS ACCESS GRAFT OR A HYBRID FEMORAL ARTERY BYPASS GRAFT IN A MAMMAL Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments of systems can include a pressure/flow loop subsystem having an external fl... | 10/02/2008 |
| 20080242923 | SYSTEMS AND METHODS OF COATING A HYBRID HEMODIALYSIS ACCESS GRAFT OR A HYBRID FEMORAL ARTERY BYPASS GRAFT IN A MAMMAL Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments of systems can include a pressure/flow loop subsystem having an external fl... | 10/02/2008 |
| 20080215136 | DIFFERENTIAL DRUG RELEASE FROM A MEDICAL DEVICE The invention relates to a medical device, such as an intravascular stent, useful for delivering two or more therapeutic agents to a body tissue of a patient at different rates, and methods for making and using such medical device. The medical device includes a substrat... | 09/04/2008 |
| 20080215139 | STENT WITH A COATING FOR DELIVERING A THERAPEUTIC AGENT The invention relates generally to a medical device for delivering a therapeutic agent to the body tissue of a patient, and methods for making such a medical device. More particularly, the invention is directed to a stent, such as an intravascular stent, having an inner... | 09/04/2008 |
| 20080195042 | Medical Devices Comprising Drug-Loaded Capsules For Localized Drug Delivery A medical device comprising a plurality of capsules, and a method of administering therapeutic agent to a patient using the same. The capsules further comprise a therapeutic agent and a multilayer polyelectrolyte shell. The medical device is adapted to apply a pressure ... | 08/14/2008 |
| 20080188924 | HYBRID STENT AND METHOD OF MAKING A stent is formed by encasing or encapsulating metallic rings in an inner polymeric layer and an outer polymeric layer. At least one polymer link connects adjacent metallic rings. The stent is drug loaded with one or more therapeutic agent or drug, for example, to reduc... | 08/07/2008 |
| 20080183282 | Use of lipid conjugates for the coating of stents and catheters This invention provides inter alia, coated device on at least a portion of a surface of the device. The device coating comprises a lipid or phospholipid moiety bound to a polypyranose. Methods of preventing, inhibiting or treating vessel damage or vessel occlusion, for ... | 07/31/2008 |