Quotables
"I watched his countenance closely, to see if he was not deranged ... and I was assured by other senators after he left the room that they had no confidence in it."
U.S. Senator Smith of Indiana ; After seeing Samuel Morse demonstrate the telegraph.
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| Application No. | Application Title | Issue Date |
| 20120130481 | LOCAL VASCULAR DELIVERY OF ADENOSINE A2A RECEPTOR AGONISTS IN COMBINATION WITH OTHER AGENTS TO REDUCE MYOCARDIAL INJURY A stent or other implantable medical device for the local delivery of a selective adenosine receptor agonist may be utilized in combination with other therapeutic agents to reduce myocardial injury following an acute myocardial infarction. As soon as possible following ... | 05/24/2012 |
| 20120130480 | LOCAL VASCULAR DELIVERY OF ADENOSINE A2A RECEPTOR AGONISTS TO REDUCE MYOCARDIAL INJURY A stent or other implantable medical device for the local delivery of a selective adenosine receptor agonist may be utilized to reduce myocardial injury following an acute myocardial infarction. As soon as possible following an acute myocardial infarction a stent or oth... | 05/24/2012 |
| 20120109284 | BARE METAL STENT WITH DRUG ELUTING RESERVOIRS HAVING IMPROVED DRUG RETENTION Implantable medical devices may be utilized to locally delivery one or more drugs or therapeutic agents to treat a wide variety of conditions, including the treatment of the biological organism's reaction to the introduction of the implantable medical device. These ther... | 05/03/2012 |
| 20120071962 | INTRAVASCULAR STENT Stents are provided with scaffold structures which have low exposures when implanted in arteries and other blood vessels and lumens. The cross-sectional dimensions, materials, and patterns are controlled to provide sufficient strength and coverage while maintaining the ... | 03/22/2012 |
| 20120071961 | Stent With Hollow Drug-Eluting Elements A stent includes a plurality of cylindrical elements joined along a common longitudinal axis to form a tube. The cylindrical elements include struts joined by crowns. Hollow, drug-eluting elements are disposed between adjacent cylindrical elements and connect adjacent c... | 03/22/2012 |
| 20120071966 | DRUG-RELEASING STENT WITH CERAMIC-CONTAINING LAYER A vascular or endoluminal stent is adapted to be implanted in a vessel, duct or tract of a human body to maintain an open lumen. The stent includes a base layer of a biologically compatible metal. An intermediate metal particle layer of substantial greater radiopacity o... | 03/22/2012 |
| 20120053677 | IMPLANT WITH A SURFACE LAYER HAVING A TOPOGRAPHIC MODIFICATION The present invention refers to an implant with a surface layer having a topographic modification. The topographic modification includes a line pattern with ridge and groove widths of 0.9 to 1.1 μm and a ridge height of more than 0.9 μm.... | 03/01/2012 |
| 20120046734 | MEDICAL DEVICES AND METHODS OF MAKING THE SAME Medical devices, such as endoprostheses, and related methods are disclosed.... | 02/23/2012 |
| 20120041540 | STENT TO BE USED IN TUBULAR ORGAN IN VIVO Provided is a stent to be inserted into an in vivo organ having a tubular structure that allows a degree of freedom in design and excellent mechanical flexibility. A cylinder-shaped stent is inserted to be placed and used in the inner cavity of an in vivo tubular organ,... | 02/16/2012 |
| 20120027834 | METHODS OF TREATMENT WITH SYK INHIBITORS The present invention provides novel compositions and methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient undergoing a vascular intervention. More particularly, the present invention provides intravascular devices coated with one or more sple... | 02/02/2012 |
| 20120029626 | DRUG DELIVERY ENDOVASCULAR STENT AND METHOD OF USE A radially expandable, endovascular stent designed for placement at a site of vascular injury, for inhibiting restenosis at the site, a method of using, and a method of making the stent. The stent includes a radially expandable body formed of one or more metallic filame... | 02/02/2012 |
| 20120029612 | COVERED TOROID STENT AND METHODS OF MANUFACTURE An expandable stent for implantation in a body lumen, such as coronary-artery, and methods for manufacturing such a stent are provided, whereby the stent comprises at least one radially expandable cylindrical crown covered with a polymeric tube. The at least one crown i... | 02/02/2012 |
| 20120016467 | POLYMER-BASED, SUSTAINED RELEASE DRUG DELIVERY SYSTEM Disclosed is a sustained release system that includes a polymer and a prodrug having a solubility less than about 1 mg/ml dispersed in the polymer. Advantageously, the polymer is permeable to the prodrug and may be non-release rate limiting with respect to the rate of r... | 01/19/2012 |
| 20120016466 | ABLUMINALLY COATED DRUG-ELUTING STENTS HAVING A FORM-FITTING PROTECTIVE LAYER A drug-eluting stent, comprising a base body that is made of an implant material, the base body being partially or entirely covered on the abluminal side with an active ingredient-releasing coating that comprises or is made of a polymer and an active ingredient having a... | 01/19/2012 |
| 20120016465 | Biodegradable Extravascular Stent The present invention relates to extravascular supports. In particular, to extravascular supports which are used in vein grafting. More in particular, it relates to extravascular supports which are biodegradable.... | 01/19/2012 |
| 20120010691 | Particle Embedded Polymer Stent and Method of Manufacture A particle embedded polymer stent and method of manufacture, which includes a stent delivery system having a catheter; a balloon operably attached to the catheter; and a polymer stent disposed on the balloon, the stent comprising struts interconnected to form a tubular ... | 01/12/2012 |
| 20120010698 | Implantable Pressure-Actuated Drug Delivery Systems and Methods of Manufacture and Use Implantable pressure-actuated systems to deliver a drug and/or other substance in response to a pressure difference between a system cavity and an exterior environment, and methods of fabrication and use. A pressure-rupturable membrane diaphragm may be tuned to rupture ... | 01/12/2012 |
| 20120004720 | G-TYPE PEPTIDES AND OTHER AGENTS TO AMELIORATE ATHEROSCLEROSIS AND OTHER PATHOLOGIES This invention provides novel peptides, and other agents, that ameliorate one or more symptoms of atherosclerosis and/or other pathologies characterized by an inflammatory response. In certain embodiment, the peptides resemble a G* amphipathic helix of apolipoprotein J.... | 01/05/2012 |
| 20110319976 | DEVICE AND METHOD FOR PREVENTING STENOSIS AT AN ANASTOMOSIS SITE The present invention relates to treating or preventing stenosis at an anastomosis site. In one embodiment, the present invention is a stent is curved along the longitudinal axis for placement in and adjacent to the graft orifice. In a further embodiment, the stent is d... | 12/29/2011 |
| 20110319977 | BIOABSORBABLE IMPLANTS A bioabsorbable implant including an elongated metallic element including more than 50% a metal substantially free of rare earth metals, with the elongated metallic element defining at least a portion of the bioabsorbable implant.... | 12/29/2011 |
| 20110319984 | Rejuvenation or preservation of germ cells Certain embodiments disclosed herein include, but are not limited to, at least one of compositions, methods, devices, systems, kits, or products regarding rejuvenation or preservation of germ cells or gametes. Certain embodiments disclosed herein include, but are not li... | 12/29/2011 |
| 20110319985 | METHODS AND APPARATUS FOR LOCALIZED ADMINISTRATION OF INHIBITORY MOIETIES TO A PATIENT Methods and devices are provided for the localized administration to a patient of moieties effective for inhibiting unwanted cellular growth, including restenosis of an artery treated with a stent implant for blockage of blood flow by an atherosclerotic lesion. After im... | 12/29/2011 |
| 20110313514 | Drug-eluting stent A drug-eluting stent comprises a coated layer prepared of a composition comprising a polymer and a drug, the coated layer being a single coated layer with the composition, or comprises a first coated layer prepared of the above composition and a second coated layer with... | 12/22/2011 |
| 20110307047 | SYSTEM AND METHODS FOR TREATING A BIFURCATION A system for treating a bifurcation includes first and second delivery catheters, each having an expandable member and a stent. The stent on the second delivery catheter has a side hole. A portion of the first delivery catheter is disposed under a portion of the stent o... | 12/15/2011 |
| 20110307053 | POLYMER METAL AND COMPOSITE IMPLANTABLE MEDICAL DEVICES A device and a method of manufacturing an implantable medical device, such as a stent, are described herein. The device includes a metallic region composed of a bioerodable metal and a polymer region composed of a biodegradable polymer contacting the metallic region. Th... | 12/15/2011 |
| 20110295365 | Anti-viral compositions and methods for administration Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, articles of manufacture, systems, and devices. Certain embodiments relate to anti-viral compositions, methods, articles of manufacture, systems and devices.... | 12/01/2011 |
| 20110282430 | Endoprosthesis In embodiments, a stent includes a copolymer having a modulus of about 10 MPa or less and exhibiting hydrolytic degradation substantially by surface erosion.... | 11/17/2011 |
| 20110282436 | Endoprosthesis A stent includes a MOF which adjusts pore size upon desorption or adsorption of organic molecules.... | 11/17/2011 |
| 20110276123 | VASCULAR STENT DESIGN This invention is directed to the design of radially expandable vascular stents to optimize hemodynamic flow characteristics that are favorable for the inhibition of stent-associated thrombosis, inflammation, and restenosis (neointimal formation) and that will reduce th... | 11/10/2011 |
| 20110274732 | MEDICAL DEVICE LOADED WITH FORMULATION FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE MATERIAL/S AND METHOD OF MANUFACTURE THEREOF The present invention relates to targeted drug delivery of a drug or therapeutic agent through medical devices coated with formulations comprising of therapeutic agent. The coating on medical devices comprises of therapeutic agent(s), affinity vehicle(s) and additives f... | 11/10/2011 |
| 20110270382 | Drug Delivery After Biodegradation Of The Stent Scaffolding Disclosed is a stent comprising a bioabsorbable polymeric scaffolding; and a plurality of depots in at least a portion of the scaffolding, wherein the plurality of depots comprise a bioabsorbable material, wherein the degradation rate of all or substantially all of the ... | 11/03/2011 |
| 20110264190 | STENTS AND OTHER DEVICES HAVING EXTRACELLULAR MATRIX COATING Provided herein are devices comprising a stent; and a coating on said stent comprising a polymer and an active agent, wherein the active agent comprises at least one of: extracellular matrix and an extracellular matrix component. Provided herein are methods of preparing... | 10/27/2011 |
| 20110264197 | COATED MEDICAL DEVICE A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed ther... | 10/27/2011 |
| 20110264188 | RE-ESTABLISHMENT OF BLOOD FLOW IN BLOCKED HUMAN ARTERIES BY TRANSFERRING NANO-ENCAPSULATED DRUG THROUGH MEDICAL DEVICES, DESIGNED FOR THE SAME AND RELEASING THE NANO-ENCAPSULATED DRUG IN HUMAN ARTERY WITH BODY PH A drug-delivering insertable medical device for treating a medical condition associated with a body lumen is disclosed. The drug-delivering insertable medical device includes an outer surface coated with two or more nano-carriers having two or more average diameters. A ... | 10/27/2011 |
| 20110264187 | Drug Eluting Folded Stent and Stent Delivery System The drug eluting folded stent and a stent delivery system, which includes a stent having a plurality of struts interconnected to form a tubular body. At least one of the struts includes a U-shaped strut having in cross-section a first leg, a second leg, and a closed end... | 10/27/2011 |
| 20110251663 | Drug Eluting Rolled Stent and Stent Delivery System The drug eluting rolled stent and a stent delivery system, which includes a catheter; a balloon operably attached to the catheter; and a stent disposed on the balloon. The stent includes a rectangular metal foil sheet having a first side and a second side, the rectangul... | 10/13/2011 |
| 20110251677 | Coating Designs For The Tailored Release Of Dual Drugs From Polymeric Coatings Provided herein are coating designs for the tailored release of two therapeutic agents from polymer coatings and methods of making and using the same.... | 10/13/2011 |
| 20110251670 | EXPANDABLE STENT THAT COLLAPSES INTO A NON-CONVEX SHAPE AND EXPANDS INTO AN EXPANDED, CONVEX SHAPE An expandable stent that can transform between a collapsed state and an expanded state is described. The stent includes a first cross-sectional shape and a second cross-sectional shape. The first cross-sectional shape is a non-convex shape when the stent is in the colla... | 10/13/2011 |
| 20110251672 | ASPECT RATIO FOR STENT STRUT DESIGN An intravascular stent is provided to be implanted in coronary arteries and other body lumens. The stent includes stent struts that have a transverse cross-section that is substantially rectangular and an aspect ratio in the range of 0.9 to 1.0 to 1.4 to 1.0. This range... | 10/13/2011 |
| 20110245904 | Implantable Prosthesis With Depot Retention Feature A prosthesis for intraluminal drug delivery can comprise a plurality of interconnected struts that form a tubular scaffold structure. The struts include through-holes with an inner surface configured to retain a bioabsorbable depot. The bioabsorbable depot includes a dr... | 10/06/2011 |
