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Pizza Pie With Concentric Rings of Crust
A pizza mold for forming a plurality of concentric raised ridges of dough (i.e., crust) on the surface of a pizza pie.
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| Application No. | Application Title | Issue Date |
| 20120108573 | SULFUR SUBSTITUTED SULFONYLAMINOCARBOXYLIC ACID N-ARYLAMIDES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM The present invention relates to compounds of the formula I wherein A1, A2, R1, R3, X and n are as defined in the claims, which are valuable pharmaceutically active... | 05/03/2012 |
| 20110313000 | CCR9 INHIBITORS AND METHODS OF USE THEREOF The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds re... | 12/22/2011 |
| 20110275635 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT Small molecule inhibitors of bacterial nicotinamide adenine dinucleotide synthetase (NADs), bacterial nicotinic acid mononucleotide adenylyltransferase (NaMNAT), and human nicotinamide mononucleotide adenylyltransferase (NMNAT) are provided, as well as methods of making... | 11/10/2011 |
| 20110190302 | Aryl-Phenyl-Sulfonamide-Phenylene Compounds and Their Use The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-phenyl-sulfonamido-phenylene compounds of the following formula (I) (collectively referred to herein as “APSAP compounds”). The present invention al... | 08/04/2011 |
| 20110136877 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS The present invention provides novel phenoxyacetic acids useful for the prevention and treatment of inflammatory disorders, including those affecting the respiratory system and skin. The compounds are of the general formula (I): ... | 06/09/2011 |
| 20110136735 | CYCLOHEXANE DERIVATIVES AND USES THEREOF The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacolog... | 06/09/2011 |
| 20110118248 | Heteroaryl sulfonamides and CCR2/CCR9 Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pha... | 05/19/2011 |
| 20110105485 | Alpha-(N-Sulfonamido)Acetamide Derivatives as Beta-Amyloid Inhibitors There is provided a series of novel α-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of β-amyloid pe... | 05/05/2011 |
| 20110077305 | 5-LIPOXYGENASE INHIBITORS The use of compounds of the formula (I) Ar1-L1-Ar2-L2-C(R3)(R4)N(OR1)C(═Y)—R2 (I) where Y is selected from O or S; R1 is H, a salt or readily hydrolysable substituent;... | 03/31/2011 |
| 20110065631 | PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS A process for the synthesis of bisfuran intermediates of formula (0) useful for preparing antiviral HIV protease inhibitor compounds is hereby disclosed. Furthermore disclosed is a HIV protease inhibitor of formula (IV) as well as various intermediates thereof. | 03/17/2011 |
| 20110065799 | UROKINASE INHIBITORS, PRODUCTION AND USE THEREOF The invention relates to novel inhibitors of urokinase and to their preparation and use for the therapy, prophylaxis and diagnosis of a tumor, in particular for reducing the formation of tumor metastases.... | 03/17/2011 |
| 20110065760 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES AND USE THEREOF The present invention is related to a compound of the formula (I), (II), (III), (IV), (V): wherein Z1, Z2, Z3 and Z4 are each and independently selected from the group comprising C(O)—, —C(S)—, —C(O)—NR10... | 03/17/2011 |
| 20110059940 | 2-Aryl Glycinamide Derivatives The disclosure provides compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their uses in inhibiting β-amyloid peptide (β-AP) production. ... | 03/10/2011 |
| 20110028509 | Sulfonamides The invention relates to compounds of formula I wherein R1, R2, R4, Ra, Rb, Rc, Re, A*, W1, W2 and W3 | |
| 20100298308 | Compositions and methods for bone formation and remodeling The mechanism by which the high bone mass (HBM) mutation (G171V) of the Wnt coreceptor LRP5 regulates the canonical Wnt signaling was investigated. The mutation was previously shown to reduce Dkk protein-1-mediated antagonism, suggesting that the first YWTD repeat domai... | 11/25/2010 |
| 20100286266 | Biphenyl-4-yl-sulfonic acid arylamides and their use as therapeutic agents The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl sulfonamides and related compounds (collectively referred to herein as ‘BPSAAA compounds’), as described herein, and including, for example, bipheny... | 11/11/2010 |
| 20100280074 | CCR9 INHIBITORS AND METHODS OF USE THEREOF The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds re... | 11/04/2010 |
| 20100273739 | Aminotetraline Derivatives, Pharmaceutical Composition, Containing Them, and Their Use in Therapy The present invention relates to aminotetraline derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions c... | 10/28/2010 |
| 20100261788 | Inhibition of Bid-Induced Cell-Death Using Small Organic Molecules Various phenylamine derivatives are described as well as the use of compounds to inhibit BID protein for controlling apoptotic cascade.... | 10/14/2010 |
| 20100234364 | CCR2 INHIBITORS AND METHODS OF USE THEREOF Compounds are provided that act as potent antagonists of the CCR2 or CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2 and CCR9. The compounds are generally aryl sulfonamide derivatives and ... | 09/16/2010 |
| 20100227902 | BIS-ARYL SULFONAMIDES Compounds are provided that act as potent antagonists of chemokine receptors. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of chemokine receptor-mediated diseases, and as controls in as... | 09/09/2010 |
| 20100210524 | NOVEL ESTROGEN RECEPTOR LIGANDS The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt, wherein W, X, Y, Z, R1, R2, R7<... | 08/19/2010 |
| 20100068272 | HYDROXYAMIDINE AND HYDROXYGUANIDINE COMPOUNDS AS UROKINASE INHIBITORS The present invention relates to novel compounds for inhibiting the urokinase plasminogen activator (uPA), which have high bioavailability and oral administerability, and also to the use thereof as therapeutic active compounds for the treatment of urokinase- or/and urok... | 03/18/2010 |
| 20100056522 | INTRAOCULAR PRESSURE-LOWERING AGENT COMPRISING COMPOUND HAVING HISTONE DEACETYLASE INHIBITOR EFFECT AS ACTIVE INGREDIENT An object of the present invention is to find a novel pharmacological effect of a compound having an HDAC inhibitory effect. The compound having an HDAC inhibitory effect of the invention has an excellent effect of cell morphological change on trabecular meshwork cells ... | 03/04/2010 |
| 20100048950 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, X, R7, and R8 are as defined herein, or a tautomer, prodrug, so... | 02/25/2010 |
| 20100041760 | MONOARYL AMINOTETRALINES The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein R1, R2 and R3 are defined in the detailed descrip... | 02/18/2010 |
| 20100022781 | TRYPSIN-LIKE SERINE PROTEASE INHIBITORS, AND THEIR PREPARATION AND USE The invention relates to inhibitors of trypsin-like serine proteases of the general formula (I) which, as well as plasmin, also inhibit plasma kallikrien, and to their preparation and use as medicaments, preferably for treatment of blood loss, especially in the case of ... | 01/28/2010 |
| 20090312328 | SULFONAMIDE COMPOUND OR SALT THEREOF [Object] A compound that can be used as an agent for treating a disease associated with an EP1 receptor, in particular, a lower urinary tract symptom. [Means for Solution] It was confirmed that a sulfonamide compound having an amide structu... | 12/17/2009 |
| 20090253669 | Substituted Sulfonamide Compounds Substituted sulfonamide compounds corresponding to the formula I: processes for the preparation thereof, pharmaceutical composition containing these compounds and the use of substituted sulfonamide compounds ... | 10/08/2009 |
| 20090131441 | Metabolites Of 2-Arylpropionic Acid Derivatives And Pharmaceutical Compositions Containing Them Metabolites of 2-(R)-4-isobutylarylpropionamides and pharmaceutical compositions containing such compounds are useful in inhibiting the chemotactic activation of neutrophils (PMN leukocytes) induced by the interaction of Interleukin-8 (IL-8) with CXCR1 and CXCR2 membran... | 05/21/2009 |
| 20090093530 | (2R)-2-[4-Sulfonyl) Aminophenyl] Propanamides and Pharmaceutical Compositions Containing Them The present invention relates to novel (2R)-2-phenylpropanamides bearing a 4-sulfonylamino substituent on the 4 position of the phenyl group and to pharmaceutical compositions containing them, which are used as inhibitors of the chemotaxis of polymorphonucleate and mono... | 04/09/2009 |
| 20090076103 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR The present invention relates to screens for compounds that can induce stem cell differentiation. In addition, isoxazoles and sulfonyl hydrazones are identified as general classes of compounds that can induce differentiation of stem cells into cells of neuronal and card... | 03/19/2009 |
| 20090054495 | CCR9 inhibitors and methods of use thereof The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds re... | 02/26/2009 |
| 20080261966 | BIS-ARYL SULFONAMIDES Compounds are provided that act as potent antagonists of chemokine receptors. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of chemokine receptor-mediated diseases, and as controls in as... | 10/23/2008 |
| 20080182906 | Novel Specific Caspase-10 Inhibitors The invention relates to compounds of the general formula (I) wherein R1, R2, R3, R4, R5, R6, i and j have the meanings given in claim 1, and to the use thereof as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy. | 07/31/2008 |
| 20080161345 | Aryl Sulfonamides The present invention relates to compounds that modulate various chemokine receptors. These compounds are useful for treating inflammatory and immune diseases.... | 07/03/2008 |
| 20080085900 | SULFONYLGUANIDINE COMPOUNDS AND PHARMACEUTICAL USES THEREOF Sulfonylguanidine compounds corresponding to the tautomeric formulas I and Ia, a method for producing them, pharmaceutical compositions containing them, and methods of using them to prepare medicaments and for treating various medical conditions. The sulfonylguanidine c... | 04/10/2008 |
| 20080070937 | SMALL MOLECULE INHIBITORS OF KYNURENINE-3-MONOOXYGENASE The present invention relates to compounds of Formula I below and their tautomers or pharmaceutically acceptable salts, compositions and methods of uses thereof. ... | 03/20/2008 |
| 20080058340 | DERIVATIVES OF N-(ARYLAMINO) SULFONAMIDES AS INHIBITORS OF MEK This invention concerns N-(2-arylamino) aryl sulfonamides, which are inhibitors of MEK and are useful in treatment of cancer and other hyperproliferative diseases. ... | 03/06/2008 |
| 20080045499 | Preferential Inhibition of Presenilin-1 The invention provides methods for determining whether an agent preferentially inhibits Presenilin-1-comprised γ-secretase relative to Presenilin-2-comprised γ-secretase. The invention also provides agents that preferentially inhibit Presenilin-1-comprised γ-secretas... | 02/21/2008 |
