...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Application No. | Application Title | Issue Date |
| 20120130131 | METHOD OF PREPARING 1-AMINO-1,3,3,5,5-PENTAMETHYLCYCLOHEXANE The invention relates to a method of producing 1-amino-1,3,3,5,5-pentamethylcyclohexane (Neramexane) or a pharmaceutically acceptable salt thereof comprising the step of heating a mixture comprising 1-chloroacetamido-1,3,3,5,5-pentamethylcyclohexane, thiourea and water.... | 05/24/2012 |
| 20120130130 | METHOD OF PREPARING NERAMEXANE The method of producing a salt of 1-amino-1,3,3,5,5-pentamethylcyclohexane comprising steps (i) to (v):
| 05/24/2012 |
| 20120130127 | METHOD OF PREPARING 1-CHLOROACETAMIDO-1,3,3,5,5-PENTAMETHYLCYCLOHEXANE Method of preparing 1-chloroacetamido-1,3,3,5,5-pentamethylcyclohexane, an intermediate in the synthesis of 1-amino-1,3,3,5,5-pentamethylcyclohexane (Neramexane) or a pharmaceutically acceptable salt thereof, comprising step (iii):
| 05/24/2012 |
| 20120014923 | HYPOGLYCEMIC EFFECT ENHANCER A hypoglycemic effect enhancer for enhancing the activity of an α-glucosidase inhibitor, the enhancer comprising at least one kind of bacteria selected from the group consisting of bifidobacteria, lactic acid bacteria, saccharifying bacteria, and butyric acid bacteria.... | 01/19/2012 |
| 20110052732 | MINERAL ABSORPTION ACCELERATOR AND IRON DEFICIENCY ANEMIA IMPROVER OF FOOD COMPOSITION A mineral absorption accelerator, and an anemia improving agent, food and drink or food and drink material containing the mineral absorption accelerator are provided, the mineral absorption accelerator including: an α-glucosidase inhibitory component.... | 03/03/2011 |
| 20100184999 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions Methods of performing cycloadditions are described that include (a) combining a first reactant and a second reactant in a hydrogen bonding solvent to form a reaction mixture; and (b) reacting the first reactant and the second reactant to form a cycloadduct. Methods of p... | 07/22/2010 |
| 20100185012 | METHOD FOR PRODUCING OPTICALLY ACTIVE TRANS-2-AMINOCYCLOHEXANOL AND INTERMEDIATE OF OPTICALLY ACTIVE TRANS-2-AMINOCYCLOHEXANOL A method of producing optically active trans-2-aminocyclohexanol includes allowing racemic trans-2-aminocyclohexanol to react with optically active 2-methoxyphenylacetic acid to produce an optically active 2-methoxyphenylacetic acid salt of optically active trans-2-amin... | 07/22/2010 |
| 20100063324 | METHOD OF OBTAINING 2-AMINO-6-ALKYL-AMINO-4,5,6,7- TETRAHYDROBENZOTHIAZOLES The present invention relates to a process for preparing 2-amino-6-alkyl-amino-4,5,6,7-tetrahydrobenzothiazoles (I) wherein the asterisk (*) represents an asymmetric carbon and R1 is C1-C6 alkyl; their enantiomers or mixtures thereof, th... | 03/11/2010 |
| 20090203910 | Deprotection of N-BOC compounds Organic compounds having nitrogen atoms protected with t-butoxycarbonyl are effectively deprotected by heating in a fluorinated alcohol solution.... | 08/13/2009 |
| 20090169495 | Merocyanine Derivatives Disclosed are merocyanine derivatives of formula (1), wherein R1 and R2 independently from each other are branched C4-C22alkyl; or branched C4-C12 alkenyl; R3 and R4 independently fr... | 07/02/2009 |
| 20090124785 | Process for production of isocyanate, isocyanate produced by the process, and use of the isocyanate An isocyanate has been widely used as a starting material for the production of a polyurethane material, a polyisocyanurate material or the like which is suitably applicable to the field of optical materials. Disclosed is a process for producing an isocyanate which incl... | 05/14/2009 |
| 20090023876 | Crosslink Agents and Dual Radical Cure Polymer Crosslink agents used to copolymerize at least one hydrophilic monomer with at least one lens monomer typically used to prepare polymeric materials for ophthalmic lenses. The crosslink agents have a relatively high selectivity for the hydrophilic monomer and limited rea... | 01/22/2009 |
| 20080312470 | Mono, Di & Tri Cyclic Compounds Useful for Lowering IgE Concentrations The present invention is directed to novel compounds which are derivatives of minocycline or doxycycline, pharmaceutical compositions containing same and use thereof in lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic.... | 12/18/2008 |
| 20080242861 | Synthesis of amino-protected cyclohexane-1,4-diyldimethanamine and its derivatives This invention relates to methods of preparing the compounds of formula (V): Each variable in this formula is defined in the specification.... | 10/02/2008 |
| 20080234319 | Novel Compounds 679 The invention provides compounds of formula (I), processes for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy, wherein R1, R2, R3 and n ar... | 09/25/2008 |
| 20080167499 | PROCESS FOR THE REDUCTIVE AMINATION OF ALDEHYDES AND KETONES Aldehyde or ketone compounds having more than one carbonyl group are reductively aminated to form a product amine compound having more than one primary amino group. The aldehyde or ketone compound is reacted with the product amine compound in the presence of an alcohol ... | 07/10/2008 |
| 20080124285 | Merocyanine Derivatives for Cosmetic Use Described are merocyanine derivatives of formula (1a) or (1b) wherein n and o are integers from 2 to 4 and aminocyclohexenone intermediates. They are used in protecting human and animal hair and skin from UV radiation. ... | 05/29/2008 |
| 20080045738 | Method for the Production of Amines from Compounds Comprising Carbodiimide Groups, by Hydrolysis With Water The invention relates to a one-stage or multistage process for preparing mono-, di- and/or polyamines from compounds having carbodiimide groups and optionally also other groups of isocyanate chemistry by hydrolysis with water.... | 02/21/2008 |
| 20080033210 | DIIMINES AND SECONDARY DIAMINES This invention provides aromatic diimines which have imino hydrocarbylidene groups with at least two carbon atoms, and aromatic secondary diamines which have amino hydrocarbyl groups with at least two carbon atoms. Both the aromatic diimines and the aromatic secondary d... | 02/07/2008 |
| 20070161798 | Method of obtaining 2-amino-6-alkyl-amino-4,5,6,7- tetrahydro-benzothiazoles The present invention relates to a process for preparing 2-amino-6-alkyl-amino-4,5,6,7-tetrahydrobenzothiazoles (I) wherein the asterisk (*) represents an asymmetric carbon and R1 is C1-C6 alkyl; their enantiomers or mixtures thereof, th... | 07/12/2007 |
| 20070010585 | Acid addition salt of carbasugar amine derivative An acid addition salt of a carba-sugar amine derivative represented by the following formula (1): wherein R1 and R2 each independently represents a hydrogen atom, or an alkyl group, an alkenyl group, an alkynyl group, an acyl group, an ar... | 01/11/2007 |
| 20050165257 | Process for preparation of voglibose A process capable of conveniently preparing voglibose at a low cost in a safe process, and an intermediate which can be suitably used in the process and a process for preparing the intermediate are provided. An inositol derivative represented by the formula (VI): 07/28/2005 | |