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| Application No. | Application Title | Issue Date |
| 20120130129 | Efficient Method for Preparing Functionalized Benzosuberenes The disclosed process can efficiently synthesize functionalized benzosuberenes. The process provides an improved method of production of benzosuberene and compounds containing a benzosuberene moiety, which is characterized by a ring closing methodology comprising reacti... | 05/24/2012 |
| 20120018710 | NOVEL POLYMERIZABLE MONOMER AND POLYMER OF THE POLYMERIZABLE MONOMER, AND MATERIAL FOR ORGANIC DEVICE, HOLE INJECTION/TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT EACH COMPRISING THE POLYMER A polymerizable monomer represented by the following formula (1) which is substituted by one or more groups comprising a polymerizable functional group wherein Ar1 and Ar4 to Ar6 are independently a substituted or unsubstituted aryl grou... | 01/26/2012 |
| 20120013245 | ELECTROACTIVE MATERIALS A compound having Formula I, Formula II, or Formula III: Ar1 may independently be phenylene, substituted phenylene, naphthylene, or substituted naphthylene. Ar2 is the same or different ... | 01/19/2012 |
| 20110294830 | NITROGEN-CONTAINING COMPOUNDS AND HARMFUL ORGANISM CONTROL AGENTS The present invention provides a nitrogen-containing compound represented by formula (I1) (in formula (I1), R0 represents a nitro group or the like, Z represents an optionally substituted aryl group or the like, R3 represents ... | 12/01/2011 |
| 20110294863 | FUNGICIDE N-CYCLOALKYL-N-BICYCLIMETHYLENE-CARBOXAMIDE DERIVATIVES The present invention relates N-cycloalkyl-N-bicyclicmethylene-carboxamide, thiocarboxamide or N-substituted carboximidamide derivatives of formula (I) wherein A represents a carbo-linked, 5-membered heterocyclyl group, T represents O or S, Z1 represents a C<... | 12/01/2011 |
| 20110281953 | PROCESS FOR PREPARING AND DRYING SOLID RASAGILINE BASE Disclosed is crystalline R(+)-N-propargyl-1-aminoindan containing water at an amount of less than 0.5% by weight and a pharmaceutical composition comprising the same, and the process for the manufacture and the validation thereof. Also disclosed is a process for the pre... | 11/17/2011 |
| 20110263719 | POLYMORPHIC FORM OF RASAGILINE MESYLATE The present invention relates to a novel crystalline form of rasagiline mesylate and a pure form of rasagiline mesylate and processes for their preparation. Further, the invention relates to pharmaceutical compositions comprising said forms and use of said compositions ... | 10/27/2011 |
| 20110251393 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME The invention provides a helicene derivative, axially chiral amino acid, amine or amino alcohol derivative, and azaperylene, such as compounds represented by Formulae (I), (I′), (II), (II′), and (III): a... | 10/13/2011 |
| 20110251288 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE AMINES The present invention relates to an improved process for the preparation of (R)-1-aminoindan (2), rasagiline (1) and pharmaceutically acceptable salts of rasagiline. ... | 10/13/2011 |
| 20110230541 | PROCESS FOR THE PREPARATION OF ROTIGOTINE A process for the preparation of Rotigotine (I) and of pharmaceutically acceptable salts thereof, which comprises the reductive amination of an amine of formula 6 with the 2-thienylacetic acid-sodium boron hydride complex and which makes use of hydrobromide 5 as an inte... | 09/22/2011 |
| 20110224256 | THERAPEUTIC IMPRINTING FOR THE TREATMENT OF PSYCHIATRIC DISORDERS The invention features methods, kits, and compositions for the treatment of psychiatric disorders using therapeutic imprinting in pre-pubescent subjects.... | 09/15/2011 |
| 20110218360 | PREPARATION OF RASAGILINE AND SALTS THEREOF The present invention relates to processes for the preparation of rasagiline mesylate. Also provided is rasagiline mesylate having 90 volume percent of the particles (D90) with sizes less than about 6 μm and processes for the preparation thereof.... | 09/08/2011 |
| 20110218361 | METHOD FOR PRODUCING COMPOUND FOR PREPARATION OF ANTI-PARKINSON'S DISEASE DRUG The present invention provides a method for producing a compound of formula (I), which is used for preparing anti-Parkinson's disease drugs, rasagiline and rasagiline mesylate. ... | 09/08/2011 |
| 20110207730 | ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment o... | 08/25/2011 |
| 20110195936 | BICYCLIC SPHINGOSINE 1-PHOSPHATE ANALOGS Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors.... | 08/11/2011 |
| 20110184071 | PROCESS FOR THE PREPARATION OF AMINES The present invention relates to an improved process for the preparation of rasagiline (1) and its pharmaceutically acceptable salts. In particular it relates to a process for preparing rasagiline (1) and its salts substantially free from impurities. | 07/28/2011 |
| 20110163300 | ORGANIC LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING ELEMENT USING THE SAME AND METHOD OF FORMING THE SAME The present invention provides compound of formula (I) wherein each substituent is defined in the specification. The compound may be used, in combination with other organic light-emitting materials, in a ligh... | 07/07/2011 |
| 20110155626 | PROCESS FOR PREPARATION OF RASAGILINE AND SALTS THEREOF The present invention relates to an improved process for the preparation of Rasagiline or pharmaceutically acceptable salts thereof. The present invention also relates to Rasagiline salts, polymorphs thereof and process for preparation thereof.... | 06/30/2011 |
| 20110152381 | 3-KETO-N-PROPARGYL-1-AMINOINDAN The subject invention provides a pharmaceutical composition containing N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of 3-keto-N-propargyl-1-aminoindan or a salt thereof.... | 06/23/2011 |
| 20110152543 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE (S)-(-)-2-(N-PROPYLAMINO)-5-METHOXYTETRALINE AND (S)-(-)-2-(N-PROPYLAMINO)-5-HYDROXYTETRALINE COMPOUNDS The present invention describes a novel process for the preparation of optically active (S)-(−)-2-(N-propylamino)-5-methoxytetraline and (S)-(−)-2-(N-propylamino)-5-hydroxytetraline compounds based on the optical resolution of mixtures of the enantiomers of 2-(N-pro... | 06/23/2011 |
| 20110117591 | CHEMICAL PROBE COMPOUNDS THAT BECOME FLUORESCENT UPON REDUCTION, AND METHODS FOR THEIR USE Chemical stain compounds containing a fluorophore and a reducible quenching unit are disclosed. The reducible quenching unit quenches the fluorophore while in its oxidized state. Upon reduction, the quenching properties of the quenching unit are diminished or eliminated... | 05/19/2011 |
| 20110117200 | RASAGILINE MESYLATE PARTICLES AND PROCESS FOR THE PREPARATION THEREOF Provided herein is rasagiline mesylate having a 90 volume-percent of the particles (D90) with a size of about 600 microns to about 1500 microns, and a process for the preparation thereof. Provided also herein are pharmaceutical compositions comprising rasagil... | 05/19/2011 |
| 20110112282 | IDO INHIBITORS AND THERAPEUTIC USES THEREOF Compounds of formula (I), and pharmaceutically acceptable salts thereof, in which each compound is adapted to occupy the binding site of human IDO, which comprises a large hydrophobic pocket A and a second, proximal hydrophobic pocket B, the compound comprising at least... | 05/12/2011 |
| 20110110871 | SUBSTITUTED 3-(PHENOXYMETHYL) BENZYL AMINES AND PERSONAL CARE COMPOSITIONS Certain novel substituted 3-(phenoxymethyl) benzyl amines and personal care compositions comprising such, which are particularly beneficial for skin lightening and achieving evenness of color, especially for face and underarm skin.... | 05/12/2011 |
| 20110105622 | PHARMACEUTICAL COMPOSITION CONTAINING GLUR2-LACKING AMPAR ANTAGONIST FOR PREVENTING OR TREATING PSYCHIATRIC ILLNESSES A pharmaceutical composition, comprising a GluR2-lacking AMPAR antagonist as an active ingredient, is effective for preventing or treating mental diseases selected from the group consisting of posttraumatic stress disorder (PTSD), drug addiction, and phobia.... | 05/05/2011 |
| 20110095282 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES The invention relates to organic electroluminescent devices which comprise triazine derivatives as the electron transport material.... | 04/28/2011 |
| 20110092666 | Pyrene-containing norbornene methylene amine and polymer thereof, and method for manufacturing the polymer The present invention discloses a pyrene-containing norbornene methylene amine which can be synthesized by 5-(amino methyl)bicycle[2.2.1]hept-2-ene (NBMA) and 1-bromopyrene. The pyrene-containing norbornene methylene amine can be used as a monomer for synthesizing a pol... | 04/21/2011 |
| 20110053980 | INDANE-AMINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS The present invention relates to indane-amine compounds of general formula (I) and compositions thereof, methods for their preparation, and the use of said compounds for the preparation of a medicament for the treatment of humans or animals.... | 03/03/2011 |
| 20110046139 | BENZOCYCLOHEPTANE AND BENZOXEPINE DERIVATIVES The present invention relates to a compound of formula (I) including any stereochemically isomeric form thereof, wherein the substituents are as defined in the specification and the claims; a N-oxide thereof,... | 02/24/2011 |
| 20110015274 | FORM OF AN AMINOINDAN MESYLATE DERIVATIVE The present disclosure relates generally to rasagiline mesylate with improved flowability and with advantageously reduced stickiness, to processes for the preparation thereof, and to the use thereof for milling and for preparing pharmaceutical formulations. Methods for ... | 01/20/2011 |
| 20100317582 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES The invention relates to novel cyclic hydrocarbon compounds and derivatives thereof, processes for the preparation thereof, to said compounds for use as a medicament, to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to meth... | 12/16/2010 |
| 20100280272 | METHOD FOR OBTAINING AN AMINOINDAN MESYLATE DERIVATIVE The invention relates to processes for preparing rasagiline mesylate that avoid the use of alcohol solvents, thereby producing rasagiline mesylate free of any alkyl mesylates, including isopropyl mesylate. The invention further relates to processes for purifying rasagil... | 11/04/2010 |
| 20100252819 | ELECTROACTIVE MATERIALS A compound having at least two diarylamino moieties and at least 10% deuteration.... | 10/07/2010 |
| 20100240617 | BICYCLIC SPHINGOSINE 1-PHOSPHATE ANALOGS Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors.... | 09/23/2010 |
| 20100227934 | THERAPEUTIC COMPOUNDS AND METHODS OF USE The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating 5-HT2C disorders, including diseases and disorders mediated by GPCRs.... | 09/09/2010 |
| 20100227865 | Oligomer-Beta Blocker Conjugates The invention provides Beta-blocker drugs that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits a different biological membrane crossing rate... | 09/09/2010 |
| 20100215710 | Beta-2 Adrenergic Receptor Agonists and Antagonists and Modulation of Wound Healing Methods for increasing rate of healing of wounds in epithelial tissues by administration of beta-2 adrenergic receptor antagonists to target patients are provided. Methods for decreasing cell growth around implanted devices and methods for decreasing wound contraction b... | 08/26/2010 |
| 20100215579 | PHEN-NAPHTHALENE AND PHEN-QUINOLINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES This invention relates to methods of imaging amyloid deposits, radiolabeled compounds, and methods of making radiolabeled compounds useful in imaging amyloid deposits. This invention also relates to compounds and methods of making compounds for inhibiting the aggregatio... | 08/26/2010 |
| 20100213825 | ELECTROACTIVE MATERIALS There is provided a compound having Formula I or Formula II: In the Formulae: Ar1 is an arylene having 6-30 carbons; Ar2 is an aryl group; Ar3 is an arylene; R1 is ... | 08/26/2010 |
| 20100210524 | NOVEL ESTROGEN RECEPTOR LIGANDS The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt, wherein W, X, Y, Z, R1, R2, R7<... | 08/19/2010 |
