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| Application No. | Application Title | Issue Date |
| 20120071664 | BETA-AMINO ACIDS AND METHODS AND INTERMEDIATES FOR MAKING SAME Disclosed are β-amino acids that are unsubstituted in the β position; that are substituted in the β position with an aryl group; that are substituted in the α position with an aryl group; that bear two substituents in the α position; and/or that are substituted in ... | 03/22/2012 |
| 20120039920 | HYDROPHOBIC MONOMERS, HYDROPHOBICALLY-DERIVATIZED SUPPORTS, AND METHODS OF MAKING AND USING THE SAME A composition is disclosed comprising a hydrophobic monomer having the structure: CH2═CR4C(O)NHC(R1R1)(C(R1R1))nC(O)XR3 wherein n is an integer of 0 or 1; R1 is independ... | 02/16/2012 |
| 20110318771 | DEUTERIUM ISOBARIC TAG REAGENTS FOR QUANTITATIVE ANALYSIS Deuterium isobaric tag reagents are provided for the quantitation of biomolecules, where the reagents contain heavy isotope atoms, including one or more 2H in each reagent. Generally, the reagents are described by the formula: reporter group—balancer group... | 12/29/2011 |
| 20110312895 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS The invention relates to compounds having either agonist or antagonist activities for the neurotrophins NGF and BDNF and represented by monomeric or dimeric substituted dipeptides that are analogs of the exposed portions of loop 1 or loop 4 regions of these neurotrophin... | 12/22/2011 |
| 20110287262 | NANOPARTICLES, NANOCAPSULES AND NANOGELS Acid-labile poly(N-vinyl formamide) (“PNVF”) nanocapsules were synthesized by free radical polymerization of N-vinyl formamide with optional active ingredients on the surface of silica nanoparticles. Polymerization in the presence of a novel cross-linker that contai... | 11/24/2011 |
| 20110269679 | INHIBITORS OF AMYLOID FIBRIL FORMATION AND USES THEREOF The present invention provides new antifibrillogenic agents and peptides, compositions and cells containing same, compositions that bind to same, effective therapeutics for preventing or delaying the progression of, e.g., Alzheimer's disease and diabetes, methods for op... | 11/03/2011 |
| 20110257433 | LIQUIDS The present invention relates to an ionic liquid comprising an anion and a cation, wherein the cation is a primary, secondary or tertiary ammonium ion containing a protonated nitrogen atom.... | 10/20/2011 |
| 20110190530 | Polycationic Viscoelastic Compositions Viscoelastic compositions are disclosed herein containing an effective amount of one or more random or structurally defined polycationic quaternary ammonium compounds for controlling the viscoelasticity of the composition. In one aspect, the present technology provides ... | 08/04/2011 |
| 20110136934 | Polychromic Substances and Their Use The invention relates to use of a diacetylene compound as a colour former wherein the diacetylene compound has one of general formulae (I) to (V). The invention also includes methods of imparting colour to a material including a compound as defined above, which comprise... | 06/09/2011 |
| 20110092420 | SELENIUM CONTAINING MODIFYING AGENTS AND CONJUGATES The invention relates to a modifying agent comprising a water soluble polymer, wherein the water soluble polymer comprises at least one reactive selenium group, said reactive selenium group being capable of reacting with a thiol group thereby forming an —Se—S— bon... | 04/21/2011 |
| 20110092601 | LYSINE-SPECIFIC DEMETHYLASE INHIBITORS Polyamine, polyamine/guanidino, and polyamine/biguanide compounds bearing allene, propargyl, cyclopropyl, and other reactive moieties are disclosed. The compounds are useful as irreversible inhibitors of the enzyme lysine-specific demethylase-1 and for the treatment of ... | 04/21/2011 |
| 20110041732 | PROCESS FOR MANUFACTURING ASPHALT A process for manufacturing asphalt is disclosed. The process comprises the steps of: (i) heating bitumen; (ii) heating aggregate; and (iii) mixing the hot bitumen with the hot aggregate in a mixing unit to form asphalt. From 10 to 200 wt % of sulphur, based upon the we... | 02/24/2011 |
| 20110017961 | Polychromic Substances and Their Use A compound which undergoes a colour change upon irradiation, and which has the general structure: X—C≡C—C≡C—Y—(CO)n-QZ wherein X is H, alkyl or —Y—(CO)n-QW; each Y is the same or a different divalent alkylene group; Q is O, S or NR;... | 01/27/2011 |
| 20110021624 | Alpha-Amino-N-Substituted Amides, Pharmaceutical Composition Containing Them and Uses Thereof Disclosed are a series of α-amino-N-substituted amide compounds having a structure of the following formula, the pharmaceutically acceptable salts thereof, and the pharmaceutical composition comprising the same. The α-amino-N-substituted amide compounds or the pharmac... | 01/27/2011 |
| 20110004019 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same The present invention provides a parakeratosis inhibitor, a pore-shrinking agent, and a rough skin inhibiting or ameliorating agent comprising, as an active ingredient, a compound that has excellent effects and high safety without safety problems such as sensory irritat... | 01/06/2011 |
| 20100324008 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and comp... | 12/23/2010 |
| 20100297023 | Lipid The present invention provides a lipid of the formula (I) R3R4N—[Y]q—(CpH2p)—X-Linker-NR1R2 (I) wherein R3 and R4 are independently selected from H and hydrocarbyl g... | 11/25/2010 |
| 20100105112 | FLUOROCARBON EMULSION STABILIZING SURFACTANTS Surfactants (e.g., fluorosurfactants) for stabilizing aqueous or hydrocarbon droplets in a fluorophilic continuous phase are presented. In some embodiments, fluorosurfactants include a fluorophilic tail soluble in a fluorophilic (e.g., fluorocarbon) continuous phase, an... | 04/29/2010 |
| 20100048909 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof An objective of the present application is to provide an industrially practicable method for producing an optically-active 3-amino-2-hydroxypropionic cyclopropylamide derivative or salt thereof from an inexpensive easily-available starting material. The derivative or sa... | 02/25/2010 |
| 20090203631 | PEPTIDE DEFORMYLASE INHIBITORS AS NOVEL ANTIBIOTICS A macrocyclic peptide deformylase (PDF) inhibitor comprising a peptide or peptide mimetic having three residues, P1′, P2′, and P3′, wherein P2′ connects P1′ and P3′, wherein P1′ and P3′ each have a ... | 08/13/2009 |
| 20090143472 | INTERMEDIATE COMPOUNDS AND THEIR USE IN PREPARATION OF LACOSAMIDE The present invention is concerned with novel compounds and their use for the preparation of lacosamide. The present invention also contemplates processes for the preparation of lacosamide employing the novel compound of general Formula II, Formula IIa or Formula IIb as... | 06/04/2009 |
| 20090130752 | BIODEGRADABLE POLY(DISULFIDE AMINE)S FOR GENE DELIVERY Poly(disulfide amine)s, methods of making, and methods of use are described. Illustrative embodiments of the poly(disulfide amine)s include poly(CBA-DAE), poly(CBA-DAB), and poly(CBA-DAH). These compositions are made by Michael addition between N,N′-cystaminebisacryla... | 05/21/2009 |
| 20090112005 | PROCESS FOR PREPARING AMIDES FROM ALCOHOLS AND AMINES The present invention provides a process for preparing amides, by reacting a primary amine and a primary alcohol in the presence of a Ruthenium catalyst, to generate the amide and molecular hydrogen. According to the process of the invention, primary amines are directly... | 04/30/2009 |
| 20090042997 | FLUOROALKYL ACID AMIDE SURFACTANTS Compounds of formula (I) and formula (III): wherein
| 02/12/2009 |
| 20080171881 | Method for Producing Organic Compound and Method for Decomposing Compound Having Dicarboximide Skeleton It is desirable to provide a method for easily removing catalyst-derived impurities from a product of a reaction by the catalysis of a compound having a dicarboximide skeleton and thereby efficiently yielding a target compound with high purity. 07/17/2008 | |
| 20080051434 | Hemiasterlin derivatives and uses thereof in the treatment of cancer The present invention provides compounds having formula (I):
| 02/28/2008 |
| 20080039655 | Amineoxide Type Surfactant and Detergent Composition Comprising It An amine oxide type surfactant, which has excellent compatibility with an anionic or non-ionic surfactant having excellent detergency and shows excellent detergency and softening effect, is represented by the following formula 1:
| 02/14/2008 |
| 20070202598 | NEW TRANSFECTION REAGENTS Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein
| 08/30/2007 |
