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| Application No. | Application Title | Issue Date |
| 20120070394 | METHIONINE-DERIVED PEPTIDOMIMETICS AND THEIR USE IN THE PROTECTION OF MITOCHONDRIA OF CUTANEOUS CELLS The invention concerns a methionine-derived peptidomimetic represented by the following general formula (II):
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| 20120041233 | FLUOROSULFONYL IMIDE SALT AND METHOD FOR PRODUCING FLUOROSULFONYL IMIDE SALT The present invention provides a method for producing a fluorisulfonylimide salt, which enables reducing the impurity content and continuous operation for a long time, and a fluorosulfonyl imide salt. The fluorosulfonyl imide salt of the present invention has a K conten... | 02/16/2012 |
| 20110301235 | ORGANOSELENIUM COMPOUNDS AND USES THEREOF Provided herein are organoselenium compounds and pharmaceutical compositions thereof. Also provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders using the compounds and pharmaceutical compositions provided herein.... | 12/08/2011 |
| 20110269170 | pH Sensitive Metal Nanoparticle and Preparation Method The present invention relates to a pH sensitive particle, a method of preparation thereof, and a use thereof. More particularly, the invention provides a pH sensitive metal nanoparticle and its use for medical treatment utilizing cell necrosis during photothermal therap... | 11/03/2011 |
| 20110257107 | Compounds for Delivering Amino Acids or Peptides with Antioxidant Activity into Mitochondria Disclosed are compounds containing single amino acids, peptides, or derivatives thereof which are selectively delivered to the mitochondria of a cell. Compounds of the invention exhibit antioxidant activity thereby reducing reactive oxygen species in cells. These compou... | 10/20/2011 |
| 20110237765 | Amide-linked Perfluoropolyether Thiol Compounds and Processes for their Preparation and Use A perfluoropolyether thiol compound comprises a perfluoropolyether segment, at least one mercapto group (—SH), and at least one intervening divalent carbonylimino moiety (—C(═O)—NR—, wherein R is hydrogen or alkyl). The compound can be produced, for example, b... | 09/29/2011 |
| 20110237776 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS Compounds useful as nutritional supplements, antioxidants, heavy metal chelators and/or as intermediates for producing other related compounds with like uses have a formula: where R1 is an aromatic... | 09/29/2011 |
| 20110196014 | METHIONINE ANALOGS AND METHODS OF USING SAME Provided are methionine analogs which may be useful for inhibiting protein synthesis, inhibiting microbial growth and/or treating infectious diseases. In some instances, the analogs exhibit bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfec... | 08/11/2011 |
| 20110136878 | AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD A pest control agent containing a compound represented by the following Formula (1), wherein A represents a carbon atom, a nitrogen atom, or the like, K represents a non-metal atom group necessary for forming a cyclic linking group derived from a 5- or 6-membered aromat... | 06/09/2011 |
| 20110124664 | Polycationic Compounds And Uses Thereof Aspects of the present invention relate to compounds and methods useful in modulating angiogenesis and methods of treating or preventing diseases associated with angiogenesis by administering a polycationic compound. The present invention relates to methods of use and c... | 05/26/2011 |
| 20110082120 | SUBSTITUTED THIOACETIC ACID SALICYLATE DERIVATIVES AND THEIR USES The invention relates to substituted thioacetic acid salicylate derivatives; compositions comprising an effective amount of a substituted thioacetic acid salicylate derivative; and methods for treating or preventing an metabolic disease comprising the administration of ... | 04/07/2011 |
| 20110040123 | Bifunctional compound containing amino group and diaminedithiol ligand and manufacturing method thereof A bifunctional compound containing an amino group and diaminedithiol ligand and a manufacturing method thereof are revealed, the bifunctional compound includes at least one amino group and a diaminedithiol (N2S2) ligand. The amino groups is for rea... | 02/17/2011 |
| 20110016642 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION The present invention relates to the dyeing of keratin materials using two colorless dye precursors, at least one of which contains a disulfide/thiol unit, said precursors reacting together chemically to form the color in situ. The process according to the invention mak... | 01/27/2011 |
| 20100305331 | ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositi... | 12/02/2010 |
| 20100298344 | Polycationic Compounds And Uses Thereof Aspects of the present invention relate to compounds and methods useful in modulating angiogenesis and methods of treating or preventing diseases associated with angiogenesis by administering a polycationic compound. The present invention relates to methods of use and c... | 11/25/2010 |
| 20100286109 | AMIDE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS AND METHODS OF USE THEREOF The invention relates to novel amide derivatives that are positive allosteric modulators of neuronal nicotinic receptors, compositions comprising the same, processes for preparing such compounds, and methods for using such compounds and compositions.... | 11/11/2010 |
| 20100261788 | Inhibition of Bid-Induced Cell-Death Using Small Organic Molecules Various phenylamine derivatives are described as well as the use of compounds to inhibit BID protein for controlling apoptotic cascade.... | 10/14/2010 |
| 20100196502 | Isoform Selective HDAC Inhibitors One aspect of the invention relates to isoform-selective HDAC inhibitors. Also provided are methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy. The invention also provides methods for treating cancer, methods for treating neurological diseases... | 08/05/2010 |
| 20100197736 | CETP ACTIVITY INHIBITORS The present invention provides a CETP activity inhibitor comprising as an active ingredient a compound represented by the formula (I): wherein R represents a straight chain or branched alkyl group; a straight... | 08/05/2010 |
| 20100081665 | Anti-Malarial Compounds The present invention provides tricyclic compounds, arylamide compounds, and other compounds, and compositions comprising the same, for treating malaria, and methods of treating malaria comprising administering such compounds to an animal.... | 04/01/2010 |
| 20100062937 | BENZANILIDES WITH INSECTICIDAL ACTIVITY Benzanilides of the formula: in which X represents hydrogen, halogen, nitro, C1-6 alkylthio, C1-6 alkylsulfinyl, C1-6 alkylsulfonyl or C1-6 alkylsulfonyloxy; Y repr... | 03/11/2010 |
| 20090312569 | NOVEL PROCESS The present invention relates to a process for the preparation of 1-(2-ethyl-butyl)-cyclohexanecarboxylic acid which is useful as an intermediate in the preparation of pharmaceutically active compounds.... | 12/17/2009 |
| 20090253672 | Cathepsin Cysteine Protease Inhibitors This invention relates to a novel class of compounds, represented by the formula (I) below, wherein the meanings of R1, R2, R3, R4, R5, R6, R7, X and Y are indicated therein, which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsms K... | 10/08/2009 |
| 20090163543 | Histone Deacetylase Inhibitors and Methods of Use Thereof One aspect of the invention relates to HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided. The invention also provides methods for treating cancer and methods for treating neurological diseases. Additionally,... | 06/25/2009 |
| 20090118375 | Optically active phthalamides Novel optically active phthalamides of the formula (I) in which A, q, R1, R2, E1, E2, X, m, Y, n and Z are as defined in the description, processes for preparing these compounds and their use for controlling pests. 05/07/2009 | |
| 20090099204 | Amide derivative, insecticide containing the same and method for application thereof as insecticide The present invention is to provide a compound represented by the general formula (1) exhibiting a high insecticidal effect and an insecticide comprising the compound as an active ingredient. The compound represented by the general formula ... | 04/16/2009 |
| 20090091234 | ROOM TEMPERATURE MOLTEN SALT AND DISPLAY ELEMENT A salt molten at room temperature that does not contain any organic solvent, excelling in stability; and a display device that is improved in the durability in high-temperature environment by virtue of the use thereof. There is provided a salt molten at room temperature... | 04/09/2009 |
| 20090053817 | FIXED CHARGE REAGENTS The present invention relates to fixed charge reagents and kits for use in tandem mass spectrometry methods involving multiplex analysis. The compounds of the invention are phenacylamide compounds. The invention also relates to methods for the quantification of for exam... | 02/26/2009 |
| 20090036311 | Benzoyl-Substituted Alanines The present invention relates to benzoyl-substituted alanines of the formula I in which the variables R1 to R12 are as defined in the description, | 02/05/2009 |
| 20080299637 | Production of Conjugates A method of reacting a first chemical entity and a second chemical entity to form a conjugate in which the first and second chemical entities are covalently bound with respect to each other, comprises bringing into simultaneous contact the first chemical entity, the sec... | 12/04/2008 |
| 20080287499 | N-DEACETYLTHIOCOLCHICINE DERIATIVES, THEIR USE AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM Disclosed is a series of N-deacetylthiocolchicine derivatives of formula I
| 11/20/2008 |
| 20080261235 | Novel Green and Orange Fluorescent Labels and Their Uses The present invention provides novel fluorescent compounds and covalent attachment chemistries which facilitate the use of these compounds as labels for ultrasensitive and quantitative fluorescent detection of low levels of biomolecules. In a preferred embodiment, the f... | 10/23/2008 |
| 20080200542 | Benzoyl-Substituted Serineamides The present invention relates to benzoyl-substituted serineamides of the formula I in which the variables R1 to R11 are as defined in the description, | 08/21/2008 |
| 20080176807 | Facially amphiphilic polymers and oligomers and uses thereof The present invention discloses methods of use of facially amphiphilic polymers and oligomers, including pharmaceutical uses of the polymers and oligomers as antimicrobial agents and antidotes for hemorrhagic complications associated with heparin therapy. The present in... | 07/24/2008 |
| 20080138309 | Use Of Aminodithiol As A Reducing Agent For Hair Perming The present invention relates to the use of aminodithiols as reducing agents for hair perming. It further relates to a hair perming method using these aminodithiols.... | 06/12/2008 |
| 20080095704 | Imaging Agents with Improved Pharmacokinetic Profiles The invention relates to compounds suitable for use in an imaging agent said imaging agent showing an improved pharmacokinetic profile.... | 04/24/2008 |
| 20080027109 | CETP Activity Inhibitors The present invention provides a CETP activity inhibitor comprising as an active ingredient a compound represented by the formula (I): wherein R represents a straight chain or branched alkyl group; a straight chain or branched alkenyl group; a lower haloalkyl ... | 01/31/2008 |
| 20070269842 | Assay for Acetyltransferases and Acetyltransferase Substrates Methods of identifying an acetyltransferase substrate in a sample are provided. Also provided are methods of localizing acetylation of an acetyltransferase substrate in a cell. Additionally, methods of labeling a protein substrate of an acetyltransferase are provided, a... | 11/22/2007 |
| 20070265266 | Active Agents Combination Exhibiting Insecticidal and Acaricide Properties The novel active compound combinations of cyclic ketoenols of the formula (I) and the active compounds of the formula (II) listed in the description have very good insecticidal and acaricidal properties. ... | 11/15/2007 |
| 20070254958 | Phenyl Carboxamide Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease The present invention is directed to phenyl carboxamide compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also direct... | 11/01/2007 |
