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Class 564/15 - Phosphorus attached indirectly to amino nitrogen by nonionic bonding


Subclass of Class 564 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which contain phosphorus indirectly attached to
No. of applications: 104
Last issue date: 05/03/2012


1      
Application No.Application TitleIssue Date
20120108549NEUROPROTECTIVE COMPOUNDS AND THEIR USE
Apocynin derivative compounds, active pharmaceutical ingredients, dosage forms, and methods of use thereof as neuroprotectants in the brain of mammals....
05/03/2012
20110319363NOVEL PHOSPHONIC ACID COMPOUNDS AS INHIBITORS OF SERINE PROTEASES
The present invention is directed to phosphonic acid compounds useful as serine protease inhibitors, compositions thereof and methods for treating inflammatory and serine protease mediated disorders....
12/29/2011
20110305632PROCESS FOR THE PREPARATION OF ASYMMETRICAL BIS(THIOSEMICARBAZONES)
The present invention relates to a method of making asymmetrical bis(thiosemicarbazones), compounds useful as synthetic intermediates in the method, new bis(thiosemicarbazones) that can be readily accessed by use of the method and methods of treatment and imaging utilis...
12/15/2011
20110294758NOVEL ACTIVATORS OF GLUCOKINASE
The present invention provides for novel compounds of Formulas I and II and pharmaceutically acceptable salts and co-crystals thereof which have glucokinsae activator activity. The present invention further provides for pharmaceutical compositions comprising the same as...
12/01/2011
20110282098Macromolecular Antioxidants Based on Sterically Hindered Phenols and Phosphites
Sterically hindered phenol and phosphite based compounds, represented by a formula selected from I-III:

and their use as antioxidants in a wide range of materials including, but not limited to, food, plastics...

11/17/2011
20110223093IONIC LIQUID SYSTEMS FOR CARBON DIOXIDE AND SULFUR DIOXIDE REMOVAL
This invention relates to sulfur functionalized ionic liquid compounds that are useful in methods of carbon dioxide or sulfur dioxide removal to which they may be applied....
09/15/2011
20110201563CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding t...
08/18/2011
20110165563DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS
Embodiments of the present disclosure relate generally to reporter compositions which are synthetic nucleotides that comprise nucleotides with a high charge mass moiety attached thereto via a linker molecule. The linker molecules can vary in length in part to enable the...
07/07/2011
20110118199USE OF CNS PENETRATING ANTICANCER COMPOUNDS FOR THE TREATMENT OF PROTOZOAL DISEASES
The present invention relates to the treatment of protozoal diseases by administering cytotoxic and/or cytostatic compounds, in particular those used in anticancer therapy, to patients. In particular, the invention relates to the use of anticancer agents that can penetr...
05/19/2011
20110110984Oral Dosage Form Comprising Tri-Substituted Glycerol Compounds
The present invention relates to pharmaceutical solid dosage forms for oral administration comprising a tri-substituted glycerol compound or a pharmaceutically acceptable salt thereof. The invention also relates to a corresponding method for preparing such dosage forms ...
05/12/2011
20110092683PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF
There are provided compounds of formulas (VA), (VIA), (VIIA) (IXA), (XIA), (XIIA), (XIIIA), and (XIVA):

    • 04/21/2011
20110071310DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD
Provided is an efficient technology for synthesizing diamino acids (diamino acid derivatives). Disclosed is a manufacturing method for diamino acid derivatives wherein the fluorenyl groups of the diamino acid derivative starting materials represented by General Formula ...
03/24/2011
20110064660DEUTERATED ALKYL PHOSPHOLIPID COMPOUNDS, COMPOSITIONS, AND METHODS OF USE
The invention generally relates to novel deuterated phospholipid compounds, compositions comprising these compounds, and their use in a variety of cancer therapy and diagnostic applications....
03/17/2011
20110054216NOVEL PROCESS FOR MAKING (2R)-(3-AMINO-2-FLUOROPROPYL)PHOSPHINIC ACID FORM A
The present invention is directed to a novel process for the preparation of the crystalline form A of (2R)-(3-amino-2-fluoropropyl)phosphinic acid....
03/03/2011
20110046239CALCIUM BASED CARRIER PARTICLES
The present invention relates to a method for forming a calcium-based carrier particle consisting of the calcium-based material, an active, with or without a surface modification, a stabilizing agent, and the related composition. The calcium-based particle is illustrate...
02/24/2011
20110046238CALCIUM BASED CARRIER PARTICLES
The present invention relates to a method for forming a calcium-based carrier particle consisting of the calcium-based material, an active, with or without a surface modification, a stabilizing agent, and the related composition. The calcium-based particle is illustrate...
02/24/2011
20110046241CALCIUM BASED CARRIER PARTICLES
The present invention relates to a method for forming a calcium-based carrier particle consisting of the calcium-based material, an active, with or without a surface modification, a stabilizing agent, and the related composition. The calcium-based particle is illustrate...
02/24/2011
20110028761PROCESS FOR THE PREPARATION OF TRIAMIDES FROM AMMONIA AND AMIDODICHLORIDES
The invention relates to a process for the preparation of triamides from ammonia and amido-dichlorides....
02/03/2011
20100284931FLUORESCENT PHOSPHOLIPID ETHER COMPOUNDS, COMPOSITIONS, AND METHODS OF USE
The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and their use in a variety of diagnostic applications, including fluorescence imaging of tumors. A preferred compound of the present invention has the f...
11/11/2010
20100253212LIGHT-EMISSION MATERIAL AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME
The invention provides a light-emission material comprising a compound having Formula (I):

    • 10/07/2010
20100240615NITRIC OXIDE DONORS
The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria....
09/23/2010
20100228052PROCESS FOR THE SYNTHESIS OF IBANDRONATE SODIUM
The present invention relates to an improved process for the synthesis of Ibandronate sodium of formula (I). The present invention also provides novel processes for the synthesis of 3-[N-(methylpentyl)amino]propionic acid (III)....
09/09/2010
20100186961ALPHA AMINO ACID PHOSPHONIC ACID COMPOUNDS, METHOD OF PREPARATION OF USE THEREOF
Novel aminoacid alkylphosphonic acid compounds are disclosed. These compounds can be used in multiple applications, in particular in a scale inhibitor functionality in aqueous systems, including in marine oil recovery....
07/29/2010
20100172967COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE
Objects of the present invention are to provide a compound which is useful as a surface modifier for producing a drug carrier or the like, or a salt thereof; a fine particle comprising the same; and the like. The present invention provides a compound in which a substanc...
07/08/2010
20100160258Bicyclic aryl sphingosine 1-phosphate analogs
Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors....
06/24/2010
20100152465Functionalized Ionic Liquids, and Methods of Use Thereof
One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of an ionic liquid comprising a pendant Bronsted-acidic group to catalyze a B...
06/17/2010
20100125149IBANDRONATE SODIUM POLYMORPHS
There are provided crystalline forms of Ibandronate sodium and process for preparing thereof....
05/20/2010
20100125132PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS
A method for making diazo-compounds, diazonium salts thereof and other protected forms of these compounds. Diaz-compounds are prepared by reaction of a tertiary phosphine reagent carrying a reactive carbonyl group with an azide. The reaction can also generate an acyl tr...
05/20/2010
20100125144HYDROGENATION OF ESTERS WITH RU/TETRADENTATE LIGANDS COMPLEXES
The present invention relates to the field of catalytic hydrogenation and, more particularly, to the use of Ru complexes with tetradentate ligands having at least one amino or imino coordinating group and at least one phosphino coordinating group in hydrogenation proces...
05/20/2010
20100111930Methods and Compositions for Detecting Receptor Ligand Mimetics
A method to determine the utility of small molecules as functional replacements (mimetics) for protein receptor ligands is described. The method uses cellular biological assays on a systematic array of compounds, comprising known protein receptor ligands and other biolo...
05/06/2010
20100113397SYNTHESIS OF OSELTAMIVIR CONTAINING PHOSPHONATE CONGENERS WITH ANTI-INFLUENZA ACTIVITY
Novel phosphonate compounds are described. The compounds have activity as neuraminidase inhibitors against wild-type and H274Y mutant of H1N1 and H5N1 viruses. The present disclosure also provides an enantioselective synthetic route to known neuraminidase inhibitors ose...
05/06/2010
20100092386SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI
The present invention relates to a novel delivery system for delivering therapeutic agents into living cells, and more particularly, to novel chemical moieties that are designed capable of targeting and/or penetrating cells or other targets of interest and further capab...
04/15/2010
20100094001COMPOSITION CONTAINING STABILITY-IMPROVED CHLOROMETHYL PHOSPHATE DERIVATIVE AND PROCESS FOR PRODUCING SAME
The present invention provides a process or the like which is employed for producing chloromethyl phosphate derivatives that are useful for producing water-soluble prodrugs, and which are excellent from the points of view of workability, operativity and energy saving. A...
04/15/2010
20100087400Beta-Hydroxy-Gamma-Aminophosphonates and Methods for the Preparation and Use Thereof
The present invention provides β-hydroxy-γ-aminophosphonates, β-amino-γ-aminophosphonates, and analogs thereof that inhibit carnitine acyltransferases. The invention also provides compositions comprising these β-hydroxy-γ-aminophosphonates, β-amino-γ-aminophosph...
04/08/2010
20100081634Novel Phosphorus-Containing Thyromimetics
The present invention relates to compounds of phosphonic acid-containing T3 mimetics and monoesters thereof, stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and pharmaceutically acceptable salts and co-crystals of the prodrugs, as wel...
04/01/2010
20100069618PROCESS FOR PREPARING MATERIALS BY GRAFTING HALOGENATED PHOSPHORUS-CONTAINING GROUPS ONTO AN INORGANIC SURFACE
The invention concerns a process for preparing a hybrid organic-inorganic material (HOIM) with phosphorus-containing bridges between the surface of an inorganic substrate containing an element M and one or more organic groups of the covalent M-O-P-R type, said process u...
03/18/2010
20100048866WATER-SOLUBLE PHOSPHINOTHIOL REAGENTS
Water soluble reagents and methods for the formation of an amide bond between a phosphinothioester and an azide in an aqueous medium. The phosphinothioester is generated using a water-soluble phosphinothiol reagent. This reaction allows formation of an amide bond betwee...
02/25/2010
20100036081Diamine Compound Having Phosphorylcholine Group, Polymer Thereof, and Process for Producing the Polymer
Highly polymerizable diamine compounds having a phosphorylcholine group are disclosed. High-molecular weight polymers are obtained from the highly polymerizable diamine compound having a phosphorylcholine group as a monomer, and the polymers have improved mechanical str...
02/11/2010
20100016258PHOSPHONATE DERIVATIVES AS AUTOTAXIN INHIBITORS
The present invention provides β-hydroxy phosphonate compounds that are autotaxin inhibitors....
01/21/2010
20100003616PHOTOSENSITIVE SELF-ASSEMBLED MONOLAYER FOR SELECTIVE PLACEMENT OF HYDROPHILIC STRUCTURES
A photosensitive monolayer is self-assembled on an oxide surface. The chemical compound of the photosensitive monolayer has three components. A first end group provides covalent bonds with the oxide surface for self assembly on the oxide surface. A photosensitive group ...
01/07/2010
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