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Class 562/560 - Ureido, hydrazino, or nitrogen double bonded directly to carbon


Subclass of Class 562 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the acid contains the ureido group (N-C
No. of applications: 47
Last issue date: 05/03/2012


1    
Application No.Application TitleIssue Date
20120107835METHOD FOR DETECTING BETA-AMYLOID USING AMINO ACID DIMERS
A method for detecting β-amyloid using an amino acid dimer instead of a secondary antibody binding to the β-amyloid primary antibody in an immunoassay based on an antigen-antibody reaction, and a kit for detecting β-amyloid including the dimer. The method is advantag...
05/03/2012
20120041178Coenzyme Q10 Nanoparticles, Preparation Method Thereof and Composition Containing Said Nanoparticles
Provided are a coenzyme Q10 nanoparticle, a method of preparing the same and a composition having the nanoparticle. According to the present invention, Coenzyme Q10 may be dissolved in only a water-miscible organic solvent, and easily made into a nano-sized particle and...
02/16/2012
20120010291CREATINE Beta-ALANINATE: A NOVEL SALT FOR INCREASING ATHLETIC PERFORMANCE
Disclosed are creatine β-alaninate, compositions and formulations containing same, and methods of use therefor....
01/12/2012
20110275590CONJUGATES FOR CANCER THERAPY AND DIAGNOSIS
The present invention relates to conjugates of a drug and an amino acid or an amino acid derivative or analog, pharmaceutical compositions that include the conjugates and methods of use thereof. In particular, the present invention relates to conjugates of anti-prolifer...
11/10/2011
20110272691Functional material for printed electronic components
The invention relates to a printable precursor comprising an organometallic aluminium, gallium, neodymium, ruthenium, magnesium, hafnium, zirconium, indium and/or tin complex or a mixture thereof which contains at least one ligand from the class of the oximates, for ele...
11/10/2011
20110245344ARGININE DERIVATIVE AND COSMETIC CONTAINING THE SAME
An object of the invention is to provide a novel arginine derivative and a cosmetic satisfactory in compatibility with the skin and hair, excellent in skin softening effect and skin-conditioning effect, and satisfactory in use feeling with little sticky feeling and tens...
10/06/2011
20110223105NEW 5-AMINOLEVULINIC ACID PRODRUGS FOR USE IN PHOTODYNAMIC THERAPY AND PHOTODYNAMIC DIAGNOSIS
There is provided a compound of Formula

and salts thereof wherein

  • R1 is an imine or an alkylated imine, said imine or alkylate...
09/15/2011
20110123976Biomarkers and identification methods for the early detection and recurrence prediction of breast cancer using NMR
A method is provided for the parallel identification of one or more metabolite species within a biological sample. The method comprises analyzing the sample to produce a spectrum containing individual spectral peaks representative of the one or more metabolite species c...
05/26/2011
20110104137ADJUNCTS AND COMPLEXES FOR IMPROVING HMG-CoA REDUCTASE INHIBITOR (STATIN) AND SELECTIVE PHOSPHODIESTERASE 5 INHIBITOR THERAPY
Dosage forms and methods of use are disclosed for a) adjuncts administered individually or simultaneously with HMg-CoA reductase inhibitors (statins) and/or selective phosphodiesterase 5 inhibitors or, b) the administration of a conjugate consisting of the adjuncts and ...
05/05/2011
20110092601LYSINE-SPECIFIC DEMETHYLASE INHIBITORS
Polyamine, polyamine/guanidino, and polyamine/biguanide compounds bearing allene, propargyl, cyclopropyl, and other reactive moieties are disclosed. The compounds are useful as irreversible inhibitors of the enzyme lysine-specific demethylase-1 and for the treatment of ...
04/21/2011
20110053848PRODRUG COMPRISING A DRUG LINKER CONJUGATE
The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising a drug linker conjugate D-L, wherein -D is an amine containing biologically active moiety; and -L is a non-biologically active linker moiety -L1 represented by...
03/03/2011
20110044965L-CITRULLINE FOR TREATING ENDOTHELIAL DYSFUNCTION AND ERECTILE DYSFUNCTION
L-citrulline for treatment of endothelial dysfunction and in particular of erectile dysfunction and a pharmaceutical composition comprising L-citrulline in combination with one or more substances selected from the group consisting of pycnogenol, aqueous extract of Vi...
02/24/2011
20110039705GRANULAR AGROCHEMICAL COMPOSITION AND METHOD OF PRODUCING THE SAME
A method of producing a granular agrochemical composition having excellent handling properties, wherein a powdered agrochemical wettable composition or powdered agrochemical water-soluble composition is converted in form to a granular agrochemical composition, without a...
02/17/2011
20110034421CREATINE ORAL SUPPLEMENTATION USING CREATINE HYDROCHLORIDE SALT
The present invention is directed to a third generation form of creatine, specifically a creatine hydrochloride salt, that drives significant improvements in muscle development and recovery due to its enhanced bio-availability, while causing fewer negative side effects ...
02/10/2011
20110008306CREATINE-LIGAND COMPOUNDS AND METHODS OF USE THEREOF
The present invention provides methods of treating creatine responsive states, such as a neurological disorder (i.e., Huntington's disease, Parkinson's disease, amyotrophic lateral sclerosis and creatine transporter defect) or a skin disorder, by administering a creatin...
01/13/2011
20100311962Agents For Magnetic Imaging Method
The invention provides MRI detectable species of formula (I)


Dp-Sn-Nm  (I)

    • 12/09/2010
20100130432Non-Natural Amino Acids and Neurotensin Analogues Thereof
This invention relates to non-natural desamino amino acid compounds, methods of making, and peptides containing these compounds as their N-terminus moieties. A preferred example is neurotensin (8-13) in which the N terminus is an alpha desamino N,N dimethyl homolysine r...
05/27/2010
20100121105Composition and Method of synthesizing a biomolecule and its therapeutics applications
It is disclosed a method which relates to the ex-vivo of synthesizing J-Factor and its therapeutic application. In-vivo mechanism involves the secretion of Growth Hormone (GH), and its binding to the GH receptor. During enzymatic interaction between GH and the receptor,...
05/13/2010
20100095749PROTEIN CRYSTALLIZING AGENT AND METHOD OF CRYSTALLIZING PROTEIN THEREWITH
The present invention provides a technique for crystallizing a desired protein at a high probability; namely, a protein crystallizing agent and a method of crystallizing protein. The present invention also provides a technique for determining the conditions for protein ...
04/22/2010
20100069290EJECTION LIQUID AND EJECTION METHOD
The ejection liquid of the present invention includes a compound having a guanidine group, and a carboxyl group or a sulfonic acid group in one molecule, and being represented by the general formula (1), or a salt of the compound, for the purpose of stably ejecting a so...
03/18/2010
20100062050MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS
This invention relates to a peptide or polypeptide (a) which is esterified or thio-esterified (i) at the carboxylate of the C-terminus with a guanidinium alkanol, a guanidinium alkanethiol, a PEG substituted with a guanidinium group and having a free hydroxyl group, or ...
03/11/2010
20090214452Arginine Heteromers for Topical Administration
The invention is directed to a strategy for providing therapeutic or cosmetic benefit to skin by topically applying arginine chemically bound to a second (non-oligo arginine) compound in order to increase transepithelial delivery of arginine through a combination of inc...
08/27/2009
20090163739Process for Preparing Creatine, Creatine Monohydrate or Guanidinoacetic Acid
A process for producing creatine, creatine monohydrate or guanidinoacetic acid is proposed, wherein firstly N-methylethanolamine or ethanolamine is catalytically dehydrogenated in each case in alkaline solution and the sarcosinate or glycinate solutions that are obtaine...
06/25/2009
20090143615Process for the Preparation of (S)(+)-3-(Aminomethyl)-5-Methylhexanoic Acid
A process for the preparation of a compound of formula (I),

comprising:

a) the reaction of a compound of formula (II)

06/04/2009

20090076110Amino Acid Compounds
An Amino Acid Compound is described. The Amino Acid Compound may comprise an Amino Acid and one of a Nitrate and a Nitrite. The Amino Acid may be one of Agmatine, Arginine, Beta Alanine, Citrulline, Creatine, Glutamine, L-Histidine, Isoleucine, Leucine, Norvaline, Ornit...
03/19/2009
20090069331GUANIDINE DERIVATIVES AS INHIBITORS OF DDAH
Compounds of formula (I) have been found to be useful as inhibitors of DDAH. The present invention thus provides the use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in the treatment of a disease...
03/12/2009
20090047654Polymer affinity matrix, a method for the production and use thereof
A polymer affinity matrix for the binding of one or more substances in a fluid or removing said substance(s) from the fluid and/or decreasing the amount or concentration thereof in said fluid with a view to preventing, eliminating or reducing undesired activation of com...
02/19/2009
20080319076COMPOSITIONS COMPRISING CREATINE SALTS AND METHODS OF USE THEREOF
The invention relates to compositions (e.g., nutritional supplements) comprising, consisting essentially of, or consisting of a creatine bicarbonate, and to methods of making and using said compositions....
12/25/2008
20080300309Creatine Hydroxycitric Acids Salts and Methods for their Production and use in Individuals
Methods of production for Tricreatine Hydroxycitrate are disclosed. Tricreatine hydroxycitrate can be used as supplemental dietary ingredient for the purposes of reducing adiposity, suppression of appetite, improvement of muscle and exercise performance and recovery. Th...
12/04/2008
20080249001AGENTS THAT ALLEVIATE SIDE-EFFECTS CAUSED BY CHEMOTHERAPY AGENTS
The present invention provides improving agents of side-effects of chemotherapy agents. Though the erythroid progenitor cells decrease due to the side-effect of chemotherapy agents, such side-effect can be improved by chemotherapy agents which comprise arginine as the a...
10/09/2008
20080233186DIETARY COMPOSITIONS AND METHODS OF ENHANCING LEAN BODY MASS AND EXERCISE PERFORMANCE
Various compounds can be administered orally to humans or animals for the purpose of enhancing nitric oxide production. Enhancing nitric oxide production is beneficial for those looking to increase lean body mass or enhance exercise performance. Such administration can ...
09/25/2008
20080221182ANTI-CANCER AND ANTI-MICROBIAL OXAZOLIDINONES
Disclosed herein are various novel oxazolidinone, imidazolidinone, and thiazolidinone analogs and methods of treating cancer and/or microbial infection using these analogs. Particular 4-oxazolidinone compounds are shown to have anti-cancer and anti-microbial activity....
09/11/2008
20080177027Compositions Containing, Methods Involving, and Uses of Non-Natural Amino Acids and Polypeptides
Disclosed herein are non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a ...
07/24/2008
20080051371Creatine phosphate analog prodrugs, compositions and uses thereof
Membrane permeable prodrugs of creatine phosphate analogs, pharmaceutical compositions comprising membrane permeable prodrugs of creatine phosphate analogs, and methods of treating diseases such as ischemia, heart failure, and neurodegenerative disorders comprising admi...
02/28/2008
20080009621Control of Cyanate in Aqueous Urea Solutions by non-1,2-Ethylene Diamine like Compounds for the Protection of Protein/Peptide Carbamylation
Embodiments of the present invention generally relate to processing of peptides in urea solutions and substantial prevention of carbamylation of the peptide. ...
01/10/2008
20080004323Iminopropene compound and use thereof
The compound (I) or a salt thereof has an excellent controlling activity against pests. Then the compound (I) or a salt thereof is useful for an active ingredient of a pesticidal composition. ...
01/03/2008
20080003208Creatine-ligand compounds and methods of use thereof
The present invention provides methods of treating creatine responsive states, such as a neurological disorder (i.e., Huntington's disease, Parkinson's disease, amyotrophic lateral sclerosis and creatine transporter defect) or a skin disorder, by administering a creatin...
01/03/2008
20070093677Creatine salts and method of making same
Disclosed are creatine salts having the general formula wherein A is a member of a group consisting of an anion of ketoglutaric acid and succinic acid. ...
04/26/2007
200700605444-Nitro-2-[(4'-methoxy)-phenoxy]-methanesulfonanilide derivatives and their pharmaceutical use
4-nitro-2-[4′-methoxy)-phenoxy]-methane-sulfonanilide or the pharmaceutical acceptable salts or solvates or hydrates thereof are provided. Also provided is their mixture with povidone, phospholipids or cyclodextrin, as well as their pharmaceutical uses, particularly t...
03/15/2007
20060264506Meldonium salts, method of their preparation and pharmaceutical composition on their basis
New salts of Meldonium, the method of their preparation, and pharmaceutical formulation on their basis have been described. The general formula of these salts is X(CH3)3N+NHCH2CH2COOH where X is an acid anion selected from the group of pharma...
11/23/2006
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