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| Application No. | Application Title | Issue Date |
| 20110245110 | Photoacid generators for the synthesis of oligo-DNA in a polymer matrix Compounds represented by the following structural formulas can be used as photoacid generators:
| 10/06/2011 |
| 20100331566 | SYNTHETIC METHODS AND COMPOSITIONS The invention provides synthetic methods that utilize bromo or chloro substituents as blocking groups during the functionalization of aromatic rings, as well as compounds that are prepared from such methods.... | 12/30/2010 |
| 20100191011 | METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXYCARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF The present invention has its object to provide a method for producing an optically active hydroxycarboxylic acid derivative which is an intermediate important for production of medicines, agrochemicals, chemical products, and so on. The production method of the present... | 07/29/2010 |
| 20080188680 | Process Improvement Using Solubility Characteristics The present invention is directed to a process of maximizing the solubility of a nonelectrolyte solute in a solvent by operating within an optimal temperature range at conditions wherein the nonelectrolyte solute is not a pure liquid. In particular, the process of the p... | 08/07/2008 |
| 20080045483 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes The invention relates to compounds of general formula (1): in which R1, R2, R3, R4, R5, A, B, D and E are as defined in Claim 1, and also to the preparation process therefor and the therapeutic use thereof. These compounds can be used in the treatment of patholog... | 02/21/2008 |
| 20070275932 | Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders Disclosed are aryl, heteroaromatic and bicyclic aryl nitrone compounds and pharmaceutical compositions containing such derivatives. The disclosed compositions are useful for preventing and/or treating pain, neurodegenerative, autoimmune and inflammatory diseases or cond... | 11/29/2007 |
| 20070155970 | PROCESS FOR THE MANUFACTURE OF HMG-COA REDUCTASE INHIBITORY MEVALONIC ACID DERIVATIVES The invention relates to a process for the manufacture of a compound of formula or a salt, especially a pharmaceutically acceptable salt with a base, thereof or a lactone thereof wherein the element | 07/05/2007 |
| 20070063189 | Compounds based on fluoranthene and use thereof The invention relates to fluoranthene derivatives of the general formula (I) in which R1, R2, R3 and a are each defined according to the description, with the proviso that at least one of the R1 or R2 radi... | 03/22/2007 |
| 20070043235 | Process for preparing 3-nitro-4-alkoxybenzoic acid The present invention provides a process for preparing 3-nitro-4-alkoxybenzoic acid, which comprises the step of subjecting a mixture comprising 4-alkoxybenzoic acid and 40-80% nitric acid, wherein the amount of the 40-80% nitric acid is equal to or more than 8 times th... | 02/22/2007 |
| 20060194825 | Ligands of adenine nucleotide translocase (ant) and compositions and methods related thereto Compounds which have utility in the treatment of conditions associated with altered mitochondrial function. The compounds having structure (I), including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein R1, R2, R... | 08/31/2006 |
| 20050267205 | 2,4-dihydroxybenzoic acid derivatives The present invention relates to novel compounds of formula (I) and to the salts, solvates and prodrugs thereof, wherein the meanings of the various substituents are as disclosed in the description. Said compounds are useful for the treatment or prevention of psoriasis... | 12/01/2005 |
| 20050234236 | Process for preparing pyridazinone compounds The present invention provides a process for the preparation 6-[3-(hetero)aryloxy-2-fluoro-benzyl]-2H-pyridazin-3-one compounds 1 where R2 is an optionally substituted aryl or an optionally substituted heteroaryl, R6 is NO2, NH2, alkyl, ... | 10/20/2005 |
| 20050165247 | Method for producing substituted nitro benzoic acids by oxidation of corresponding nitro toluenes, nitro benzyl alcohols, esters and/or ethers The present invention relates to the preparation of nitrobenzoic acids by oxidizing particular nitrotoluenes, nitrobenzyl alcohols, esters and/or ethers in the presence of nitric acid at elevated temperature and elevated pressure. It has been found that the particular n... | 07/28/2005 |
| 20050085662 | Process for the synthesis of nacyl-2-amino-4-alkoxy-5-nitrobenzoic acids The invention claimed herein provides a process to oxidize N-(5-alkoxy-2-methyl-4-nitrophenyl)acetamides to N-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids using potassium permanganate in the presence of magnesium sulfate in aqueous sulfolane or aqueous pyridine. ... | 04/21/2005 |
| 20050085664 | Process for producing chromone compound A process for producing a dicarboxylic acid compound represented by the formula (4): wherein R1 and R2 are the same or different and each represents lower alkyl and the wavy line indicates that this compound is the E- or Z-isomer or a mix... | 04/21/2005 |
| 20050080138 | Mediators of hedgehog signaling pathways, compositions and uses related thereto The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., ... | 04/14/2005 |
| 20050059638 | Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders Disclosed are aryl, heteroaromatic and bicyclic aryl nitrone compounds and pharmaceutical compositions containing such derivatives. The disclosed compositions are useful for preventing and/or treating pain, neurodegenerative, autoimmune and inflammatory diseases or cond... | 03/17/2005 |
