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Class 549/328 - Four-membered lactone ring formed


Subclass of Class 549 - Organic compounds -- part of the class 532-570 series
Definition: Processes whereby a four-membered lactone ring is formed.
No. of applications: 19
Last issue date: 01/26/2012


Application No.Application TitleIssue Date
20120022274Crystalline Form of Orlistat and a Process Thereof
The present disclosure provides a crystalline form of orlistat, particularly form A of orlistat. The characterization of said form is performed using X-ray diffraction studies, IR and Differential Scanning calorimetry melting endotherm studies. Also, the disclosure prov...
01/26/2012
20110282075METHOD FOR PREPARING VITTATALACTONE
The present invention relates to the chemical synthesis of vittatalactone, the aggregation pheromone of the striped cucumber beetle, Acalymma vittatum. ...
11/17/2011
20110046400PREPARATION METHOD OF (3S,4S)-3-HEXYL-4-((R)-2-HYDROXYTRIDECYL)-OXETAN-2-0NE AND THE PRODUCT OF THAT METHOD
The present invention relates to a method for the preparation of (3S,4S)-3-hexyl-4-((R)-2-hydroxytridecyl)-oxetan-2-one and a product of the method. The method includes the following steps: a) reducing a substance represented by formula (II) to obtain a substance repres...
02/24/2011
20100234220Oxooxetanes as Fungicidal Agents
The present invention relates to compounds of the formula (I) below

and to their agrochemically active salts and their use alone or in a mixture with other active compounds and/or auxiliaries and/or additives...

09/16/2010
20100179335PROCESS FOR THE PREPARATION OF ORLISTAT
The present invention provides a process for preparing orlistat from amino orlistat using Pivaloyl Formic Anhydride (PFA) as an alkanoylating agent....
07/15/2010
20100104979ALPHA-HYDROXYKETONES
Compounds of the Formula (I) wherein x is an integer from 1-4; p is an integer from 1-3; q is an integer from 0-3; Ar is phenyl, naphthyl, anthryl or phenanthryl each of which optionally is substituted by one or more Cl, CN, OR5, C3-C5al...
04/29/2010
20100069484SIGMA(s)-RECEPTOR LIGANDS WITH ANTI-APOPTOTIC AND/OR PRO-APOPTOTIC PROPERTIES OVER CELLULAR BIOCHEMICAL MECHANISMS, WITH NEUROPROTECTIVE, ANTI-CANCER, ANTI-METASTATIC AND ANTI-(CHRONIC) INFLAMMATORY ACTION
The present invention involves new and original sigma receptors ligands : (Mono- or di-alkylaminoalkyl)-γ-butyrolactones, their analogues aminotetrahydrofuranes, the (1-adamantyl)phenyl(s) alkylamines, the N,N Dialkyl α-[(adamantyl-1)benzyloxy-2] alkylamines and the 3...
03/18/2010
200902757562-OXETANONE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF
An aldehyde derivative represented by the general formula (2) is reacted with ketene in the presence of a Lewis acid catalyst to produce a novel 2-oxetanone derivative (1), which is then purified to a 2-oxetanone derivative having a high tran...
11/05/2009
20090171104PROCESS FOR THE PREPARATION OF ORLISTAT
The present invention provides a process for preparing orlistat (I) by alkanoylating an amino orlistat using formic acid anhydride as an alkanoylating agent to obtain orlistat substantially free of the byproduct, (S)-N-acetylleucine (1S)-1-[[(2S, 3S)-3-hexyl-4-oxo-2-oxe...
07/02/2009
20090124787Method for Producing Polyhydroxyalkanoates
The invention relates to a process for preparing polyhydroxyalkanoates by polymerization of lactones of the general formula I,

where the substituents and the index n have the meanings given in the description...

05/14/2009
20090124681BETA-LACTONE COMPOUNDS
The present invention provides compounds having the general structure A, or a pharmaceutically acceptable derivatives thereof:

wherein R is an alkyl group, and R1 comprises at least one moiety sele...

05/14/2009
20080319049Compounds For the Treatment of Metabolic Disorders
Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, polycystic ovary syndrome, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed, wherein n is 1 or 2; m i...
12/25/2008
20070213524Low pressure carbonylation of heterocycles
Heterocycles, e.g., epoxides, are carbonylated at low pressure with high percentage conversion to cyclic, ring expanded products using the catalyst

where L is tetrahydrofuran (THF)....

09/13/2007
20070208183HYDROGENATION PROCESS FOR THE CONVERSION OF A CARBOXYLIC ACID OR AN ESTER HAVING A CARBONYL GROUP
A hydrogenation process for the conversion of a reactant selected from the group consisting of a carboxylic acid having a carbonyl group and an ester of a carboxylic acid having a carbonyl group to form a carboxylic acid or an ester with a hydroxyl group or a lactone, w...
09/06/2007
20070161806Catalyst for the carbonylation of oxiraines
Lactones are prepared by the catalytic carbonylation of oxiranes using a catalyst system comprising a) at least one carbonylation catalyst A comprising uncharged or anionic transition metal complexes of metals of groups 5 to 11 of the Periodic Table, b) at least one met...
07/12/2007
20060217537Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via ketene using diazo compounds and carbon-isotope monoxide
Methods and reagents for transition metal-promoted carbonylation via diazo compounds using carbon-isotope labeled carbon monoxide are provided. The resultant carbon-isotope labeled compounds are useful as radiopharmaceuticals, especially for use in Positron Emission Tom...
09/28/2006
20060089503Processes for producing optically active 2-thiomethyl-3-phenylpropionic acid derivative and for producing intermediate therefor
The present invention provides a process for simply producing an optically active 2-thiomethyl-3-phenylpropionic acid derivative useful as an intermediate for medicines from inexpensive raw materials. An optically active 2-hydroxymethyl-3-phenylpropionic acid ester deri...
04/27/2006
20050256320Catalyst and method for the carbonylation of oxiranes
Lactones are prepared by catalytic carbonylation of oxiranes using a catalyst system comprising a) at least one cobalt compound as component A and b) at least one metal compound of the formula (I) as component B,
MXxRn-x
11/17/2005
20050240032Catalyst for the carbonylation of oxiranes
Lactones are prepared by catalytic carbonylation of oxiranes using a catalyst system comprising a) at least one carbonylation catalyst A comprising uncharged or anionic transition metal complexes of metals of groups 5 to 11 of the Periodic Table of the Elements and b) a...
10/27/2005
 
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