Did You Know...
...that the x-ray was discovered purely by accident? When German physicist Wilhelm Konrad von Roentgen was experimenting with cathode rays in 1895, he put an activated Crookes tube in a book and went out to lunch. When he returned, he discovered that a key that had also been placed in the book showed up as an image on the developed film!
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| Application No. | Application Title | Issue Date |
| 20120035187 | ANTI-NEURODEGENERATIVE DISEASE AGENT The present invention has an object to provide a novel agent for anti-neurodegenerative diseases and solves the object by providing an agent for anti-neurodegenerative diseases containing, as an effective ingredient, the compound(s) represented by the following General ... | 02/09/2012 |
| 20120022264 | METHOD FOR PRODUCING 2,2 DIFLUOROETHYLAMINE DERIVATIVES BY IMINE HYDROGENATION Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are hydrogenated to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A, R1 and R2 radicals are each ... | 01/26/2012 |
| 20120012830 | MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE THEREBY A material for an organic photoelectric device, the material including a compound represented by the following Chemical Formula 1:
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| 20120004262 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE The present invention relates to phenylcyclopropylamine derivatives. In particular, pharmaceutical compositions comprising phenylcyclopropylamine derivatives are provided. The compounds of this invention can, inter alia, be used for the treatment and the prevention of c... | 01/05/2012 |
| 20110306770 | Process for preparing 2-2-difluoroethylamine derivatives by alkylation with 2-2-difluoroethyl-1-haloethanes Process for preparing 2,2-difluorethylamine derivatives of the general formula (III) in which A is an optionally substituted heterocycle as described in the description, by reacting a 2,2-difluoroethyl-1-halo... | 12/15/2011 |
| 20110245504 | SYNTHESIS OF 9-(ARYLALKYL)-1,2,3,4-TETRAHYDRO-y-CARBOLINE AND ANALOGUES AND INTERMEDIATES The present invention pertains generally to methods of preparing certain 9-(arylalkyl)-1,2,3,4-tetrahydro-γ-carboline compounds and their analogues, and especially to methods of preparing dimebon. The present invention also pertains to methods of preparing certain inte... | 10/06/2011 |
| 20110237627 | METHODS OF SYNTHESIZING ANATABINE Anatabine is obtained by reacting benzophenoneimine with 3-aminomethyl pyridine to form benzylhydrylidene-pyridin-3-yl-methyl-amine. The benzylhydrylidene-pyridin-3-yl-methyl-amine is treated with a non-nucleophilic base and a dielectrophile, such as cis-1,4-dichloro-2-... | 09/29/2011 |
| 20110230517 | CALCIUM RECEPTOR MODULATING AGENTS The present invention relates generally to novel calcimimetic compounds and pharmaceutical compositions comprising them. The invention also relates to methods of treating of diseases or disorders related to the function of the calcium sensing receptor using the compound... | 09/22/2011 |
| 20110166190 | METHODS OF TREATING MAMMALS WITH EUSTACHIAN TUBE DYSFUNCTIONS The invention relates to methods of medically treating mammals with Eustachian tube dysfunctions, such as Ménière's disease, vertigo, Otitis Media (including Otitis Media with Effusion (OME), Acute Otitis Media (AOM) and Aerotitis Media (AM)) as well as other disorder... | 07/07/2011 |
| 20110152525 | PROCESS FOR PREPARING AMINES FROM ALCOHOLS AND AMMONIA The present invention provides novel ruthenium based catalysts, and a process for preparing amines, by reacting a primary alcohol and ammonia in the presence of such catalysts, to generate the amine and water. According to the process of the invention, primary alcohols ... | 06/23/2011 |
| 20110098429 | Catalyst Compounds and Use Thereof This invention relates to Group 4 catalyst compounds containing di-anionic tridentate nitrogen/oxygen based ligands. The catalyst compounds are useful, with or without activators, to polymerize olefins, particularly a-olefins, or other unsaturated monomers. Systems and ... | 04/28/2011 |
| 20110065705 | Compositions and Methods of Treating Cell Proliferation Disorders The invention relates to compounds and methods for treating cell proliferation disorders.... | 03/17/2011 |
| 20110046146 | Phosphodiesterase 4 inhibitors PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3and R4 are as defined herein. ... | 02/24/2011 |
| 20100298572 | METHODS OF PREPARING SECONDARY CARBINAMINE COMPOUNDS WITH BORONIC ACIDS The present application relates to novel methods for the preparation of secondary carbinamine compounds, particularly the preparation of secondary carbinamine compounds of the formula Ia, formula Ib or formula IV from aldehydes of the formula II and boronic acids of the... | 11/25/2010 |
| 20100274021 | METHOD FOR PRODUCING 2,2-DIFLUOROETHYLAMINE DERIVATIVES BY IMINE HYDROGENATION Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are hydrogenated to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A radical is as defined in the description: | 10/28/2010 |
| 20100260750 | Novel serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity Novel serotonin reuptake inhibitor compounds which are designed to exert serotonin uptake inhibitory activity in the peripheral system while being devoid of CNS activity, and a process of preparing same are disclosed. Further disclosed are pharmaceutical compositions co... | 10/14/2010 |
| 20100222593 | METHOD FOR PRODUCING 2,2-DIFLUOROETHYLAMINE DERIVATIVE BY AMIDE HYDROGENATION Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are reduced to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A radical is as defined in the description: 09/02/2010 | |
| 20100213826 | Material for organic photoelectric device, and organic photoelectric device thereby A material for an organic photoelectric device, the material including a compound represented by the following Chemical Formula 1:
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| 20100202965 | ANNULUS FIBROSUS DETECTION IN INTERVERTEBRAL DISCS USING MOLECULAR IMAGING AGENTS The present invention relates to methods for imaging annulus fibrosus tissue and a quantitative measurement of its local concentration in a sample using an agent comprising the compound of Formula I, a 13C or 2H enriched compound of Formula I, an <... | 08/12/2010 |
| 20100197930 | PROCESS FOR PRODUCING TOLUIDINE COMPOUND Because fluazinam is excellent as an active ingredient of pesticides and highly useful, it is desired to produce it efficiently in a proper form with simple operations at low cost in an environmentally friendly manner. The desired product is obtained in good yields with... | 08/05/2010 |
| 20100184741 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R1a, R1b, R1c, R1d, ... | 07/22/2010 |
| 20100179199 | Ethanamine Compounds and Methods of Using the Same 545 The present invention is directed to ethanamine compounds, pharmaceutical compositions comprising the same, and methods of treating depression by administering the ethanamine compound.... | 07/15/2010 |
| 20100174090 | METHODS OF PREPARING PRIMARY, SECONDARY AND TERTIARY CARBINAMINE COMPOUNDS IN THE PRESENCE OF AMMONIA The present application relates to novel methods for the preparation of primary, secondary and tertiary carbinamine compounds, particularly the preparation of compounds of formulae I, IV and VI, from a carbonyl compound of formula II in the presence of ammonia or an amm... | 07/08/2010 |
| 20100158818 | ANTIMICROBIAL N-CHLORINATED COMPOSITIONS The present application relates to N-chlorinated cationic compounds of Formula I or a salt thereof, and associated compositions and methods of use as antimicrobial agents.... | 06/24/2010 |
| 20100160390 | COMPOUNDS CAPABLE OF ACTIVATING CHOLINERGIC RECEPTORS Compounds incorporating aryl substituted olefinic amine are provided. Representative compounds are (4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-pyrimidinyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-methoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(6-... | 06/24/2010 |
| 20100133519 | ARYLAMINE COMPOUNDS AND ELECTRONIC DEVICES There is provided conductive organic arylamine compounds. The compounds may be prepared as films and such films may be used as a hole transporting layer, an emissive layer or an electron transporting layer in organic light emitting devices.... | 06/03/2010 |
| 20100120872 | ORGANIC COMPOUNDS AND THEIR USES The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.... | 05/13/2010 |
| 20100121054 | PROCESS FOR PRODUCING SUBSTITUTED METHYLAMINE COMPOUND AND TRIAZINE DERIVATIVE The present invention provides a process that enables a substituted methylamine compound which is useful as an intermediate for the production of agricultural chemicals and medicines, to be produced easily, with good yield, and at low cost, and also provides a productio... | 05/13/2010 |
| 20100099682 | ACETYLENE DERIVATIVES The invention provides compounds of formula (I) wherein
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| 20100069447 | BENZAMIDE DERIVATIVES AND USES RELATED THERETO Benzamide derivatives of formulae I and II, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof, and pharmaceutical compositions comprising the same, are described and have therapeutic utility, particularly in the treatment of diabetes, ... | 03/18/2010 |
| 20100036119 | FLUORINATING REAGENTS AND THEIR PREPARATION The present invention relates to α,α-difluoroamines, fluorinating reagents comprising α,α-difluoroamines and also processes for preparing α,α-difluoroamines and fluorinating reagents comprising α,α-difluoroamines.... | 02/11/2010 |
| 20100029952 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems Fluorophores derived from photoactivatable azide-pi-acceptor fluorogens or from a thermal reaction of an azide-pi-acceptor fluorogen with an alkene or alkyne are disclosed. Fluorophores derived from a thermal reaction of an alkyne-pi-acceptor fluorogen with an azide are... | 02/04/2010 |
| 20100022394 | PRODUCTS FOR THE TREATMENT OF THE IRON CHLOROSIS The present invention consists on the synthesis of new products for the treatment of the iron chlorosis. These products may have improved properties regarding the currently known treatments. The new products are non-symmetrical ethylene diamino hidroxyphenyl acetic acid... | 01/28/2010 |
| 20100022726 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof Pyridyldiamido transition metal complexes are disclosed for use in alkene polymerization. The ligands are tridentate with an NNN configuration. The general formula is: (I) ... | 01/28/2010 |
| 20100001635 | Novel organic electroluminescent compounds and organic electroluminescent device using the same The present invention relates to novel organic electroluminescent compounds, and organic electroluminescent devices employing the same in an electroluminescent layer. Specifically, the organic electroluminescent compounds according to the invention are characterized in ... | 01/07/2010 |
| 20090314990 | NOVEL TRIPHENYLAMINE DERIVATIVES USEFUL AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY Triphenylamine derivatives useful as fluorophores in biology, in particular for two-photon microscopy; and compositions comprising these derivatives, to the use of these compositions and of the derivatives themselves for labelling biologica... | 12/24/2009 |
| 20090286775 | Bicyclic Derivatives as P38 Kinase Inhibitors New bicyclic derivatives of formula (I), wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as p38 kinase inhibitors. ... | 11/19/2009 |
| 20090286275 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe A two-photon probe for real-time monitoring of intracellular free zinc ions is provided. The two-photon probe is represented by Formula 1: wherein R is H or OCH3. The two-photon probe has high sele... | 11/19/2009 |
| 20090281325 | METHOD FOR SELECTIVELY PRODUCING PRIMARY AMINE COMPOUND Disclosed is a method for producing a primary amine compound represented by the formula (3): wherein, Ar is as defined below , which is characterized in that a halogen compound represented by the formula (1):... | 11/12/2009 |
| 20090275556 | Aryl sulfonamides useful as inhibitors of chemokine receptor activity The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein R1, X, Z, R2, X1, Ar, n, R3 and R4 ... | 11/05/2009 |
