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| Application No. | Application Title | Issue Date |
| 20120129856 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILISATION The invention relates to classes of pharmaceutically-active heterocyclic compounds and pharmaceutically acceptable salts, and hydrates thereof, and compositions comprising the same. The invention also relates to methods for treating or preventing a disease or disorder, ... | 05/24/2012 |
| 20120130073 | INHIBITORS OF SYK AND JAK PROTEIN KINASES The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compoun... | 05/24/2012 |
| 20120126221 | CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE A charge-transporting material contains a compound represented by the following formula (1) in an organic layer, in which the contents of specific halogen-containing compounds are 0.1% or less to the compound represented by formula (1). In formula (1), each of A1 <... | 05/24/2012 |
| 20120104941 | COMPOUND FOR AN ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME A compound for an organic photoelectric device, an organic photoelectric device, and a display device, the compound being represented by the following Chemical Formula 3a, 3b, or 3c: ... | 05/03/2012 |
| 20120107271 | ETHYNYL-SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS The present invention provides compounds of Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and pro-drugs of said c... | 05/03/2012 |
| 20120071480 | 4-(3-AMINOPYRAZOLE) PYRIMIDINE DERIVATIVES FOR USE AS TYROSINE KINASE INHIBITORS IN THE TREATMENT OF CANCER This invention relates to novel compounds having the formula (I): and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.... | 03/22/2012 |
| 20120068170 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES The present invention describes indenocarbazole derivatives having electron- and hole-transporting properties, in particular for use in the emission and/or charge-transport layer of electroluminescent devices or as matrix material. The invention furthermore relates to a... | 03/22/2012 |
| 20120053175 | MLK INHIBITORS AND METHODS OF USE Provided are compounds having an inhibitory effect on Mixed Lineage Kinases. Also provided are pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therap... | 03/01/2012 |
| 20120040991 | 3-AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS Disclosed are 3-azabicyclo[4.1.0]heptane derivatives of formula (I) and their use as orexin receptor antagonists. ... | 02/16/2012 |
| 20120041200 | PROCESS FOR THE PREPARATION OF BOSENTAN The invention concerns a new process for the preparation of bosentan or bosentan monohydrate by reaction of compound of Formula II with ethylene glycol in the presence of potassium bases and the potassium salt of bosentan. ... | 02/16/2012 |
| 20120028983 | NOVEL COMPOUND HAVING 3-HETEROARYLPYRIMIDIN-4-(3H)-ONE STRUCTURE AND PHARMACEUTICAL PREPARATION CONTAINING SAME Disclosed is a compound which has both an angiotensin-II receptor antagonistic activity and a PPARγ activation activity and is useful as a prophylactic and/or therapeutic agent for hypertension, heart diseases, angina pectoris, cerebrovascular disorders, cerebral circu... | 02/02/2012 |
| 20120028962 | FUSED HETEROCYCLIC RING COMPOUND A compound represented by the following formula or a salt thereof, which has an GPR119 agonist action, is useful for the prophylaxis or treatment of diabetes, obesity and the like, and shows superior efficacy: 02/02/2012 | |
| 20120028997 | PROKINETICIN 1 RECEPTOR ANTAGONISTS The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 1 ... | 02/02/2012 |
| 20120029002 | BENZIMIDAZOLE AND PYRAZOLOPYRIDINE DERIVATIVES FOR TREATING AND/OR PREVENTING CARDIOVASCULAR DISEASES The present application relates to novel fused, heteroatom-bridged pyrazole and imidazole derivatives, to processes for their preparation, to their use, alone or in combination, for the treatment and/or prevention of diseases and to their use for preparing medicaments f... | 02/02/2012 |
| 20120001165 | MATERIAL FOR PHOSPHORESCENT LIGHT-EMITTING ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Provided is an organic electroluminescent device (organic EL device), which has improved luminous efficiency, has sufficient driving stability, and has a simple construction. The organic EL device of the present invention is an organic electroluminescent device, includi... | 01/05/2012 |
| 20110319614 | Organic Compounds The present invention relates to novel IAP inhibitor compounds of formula I: ... | 12/29/2011 |
| 20110319420 | PREPARATION METHOD OF DIHYDROINDENE AMIDE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS THEREOF AND USE AS PROTEIN KINASES INHIBITOR The invention provides a new kind of dihydroindene amide compounds of general formula I or their pharmaceutically acceptable salts or prodrug thereof which can be used as protein kinase inhibitor. The invention provides a preparation method of the kind of compounds, the... | 12/29/2011 |
| 20110318280 | POLYMERIC ANTI-MICROBIAL AGENTS Polymeric anti-microbial agents produced by substituting the nitrogen atoms in the backbone of ethylenimine polymers, for example, substitution with aralkyl groups, are provided. The agents are believed to have low human toxicity while being effective against a variety ... | 12/29/2011 |
| 20110312996 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION The embodiments provide compounds of the general Formulae VI, VII, VIII, IX, X, XI, XII, XIII, XIV, and XV as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods... | 12/22/2011 |
| 20110306589 | NITROGEN CONTAINING HETEROARYL COMPOUNDS The invention is concerned with novel nitrogen-containing heteroaryl compounds of formula (I) wherein A1, A2, R1,... | 12/15/2011 |
| 20110306623 | NOVEL COMPOUNDS COMPRISING A 3-(5-ALKOXYPYRIMIDIN-2-YL) PYRIMIDIN-4(3H)-ONE STRUCTURE AND DRUGS THAT COMPRISE SAME Provided are novel compounds that have both angiotensin II receptor-antagonist effects and PPAR-activating effects that are useful as agents for preventing and/or treating hypertension, heart disease, angina, cerebral vascular accident, cerebrovascular disorder, ischemi... | 12/15/2011 |
| 20110301109 | Phenylpyrimidone Compounds, the Pharmaceutical Compositions, Preparation Methods and Uses Thereof The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds of the following formula I, the p... | 12/08/2011 |
| 20110301123 | Fungicidal Heterocyclic Amines Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein
| |
| 20110294836 | ARYL GPR119 AGONISTS AND USES THEREOF Aryl GPR119 agonists are provided. These compounds are useful for the treatment of diabetic diseases, including Type II diabetes and other diseases associated with poor glycemic control.... | 12/01/2011 |
| 20110288065 | AMINOPYRAZINE DERIVATIVE AND MEDICINE The present invention relates to a compound represented by general formula [1] satisfying the following (I) or (II), or a pharmaceutical acceptable salt of the compound.
| |
| 20110288071 | SUBSTITUTED PYRIMIDINES FOR THE TREATMENT OF DISEASES SUCH AS CANCER The present invention encompasses compounds of general formula (1) wherein A, B, X, R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use... | 11/24/2011 |
| 20110281899 | METHODS OF PREVENTING AND TREATING LOW BONE MASS DISEASES The present invention provides methods and therapeutic agents for lowering or increasing serum serotonin levels in a patient in order to increase or decrease bone mass, respectively. In preferred embodiments, the patient is known to have, or to be at risk for, a low bon... | 11/17/2011 |
| 20110281872 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CANCER The invention relates to compositions and methods for the treatment and prevention of cancer and other cell proliferative disorders.... | 11/17/2011 |
| 20110275590 | CONJUGATES FOR CANCER THERAPY AND DIAGNOSIS The present invention relates to conjugates of a drug and an amino acid or an amino acid derivative or analog, pharmaceutical compositions that include the conjugates and methods of use thereof. In particular, the present invention relates to conjugates of anti-prolifer... | 11/10/2011 |
| 20110269759 | PYRIMIDINE COMPOUNDS AS DELTA OPIOID RECEPTOR MODULATORS Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein R1 | |
| 20110263853 | HPLC METHOD FOR THE ANALYSIS OF BOSETAN AND RELATED SUBSTANCES AND USE OF THESE SUBSTANCES AS REFERENCE STANDARDS AND MARKERS The present invention relates to a new HPLC method for the analysis of the drug substance bosentan and related substances and to the use of said substances as reference standards and markers.... | 10/27/2011 |
| 20110263623 | PROCESS FOR PREPARATION OF BOSENTAN The present invention provides improved processes for preparing Bosentan. The present invention provides novel intermediates like 4,6-dihydroxy-5-(2-methoxy phenoxy)[2,2′]bipyrimidine of formula (II) and N-(6-Chloro-5-(2-ethoxyphenoxy)[2,2′-bipyrimidinyl]-4-t-butyl ... | 10/27/2011 |
| 20110251169 | Arylethynyl derivatives The present invention relates to ethynyl compounds of formula I wherein
| 10/13/2011 |
| 20110245281 | DISPERSIBLE BOSENTAN TABLET The invention relates to dispersible tablets comprising the compound 4-tert-butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-(pyrimidin-2-yl)-pyrimidin-4-yl]-benzenesulfonamide.... | 10/06/2011 |
| 20110245156 | NOVEL ANTIVIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE Compounds are disclosed. Compositions that include the compounds are disclosed. Methods of making and using the compounds are also disclosed.... | 10/06/2011 |
| 20110245285 | PROCESS FOR PREPARATION OF ROSUVASTATIN ACETONIDE CALCIUM The present invention is in relation to a process for preparation of HMG-CoA reductase inhibitor. More particularly, the present invention provides a process for preparation of (3R,5S,6E) 6-{2-[4-(4-Fluoro-phenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5... | 10/06/2011 |
| 20110237578 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF Compounds are provided according to formula (I), where A, B, W, X′, L, R1, R3, R4b, and m′ are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of ... | 09/29/2011 |
| 20110227057 | PERYLENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE COMPOUND Provided is an organic light emitting device having high light emitting efficiency and good emission color purity. The organic light emitting device includes an anode, a cathode, and an organic compound layer which is sandwiched between the anode and the cathode, in whi... | 09/22/2011 |
| 20110229918 | Method of Quantifying Transient Interactions Between Proteins The invention relates to a precursor for producing sintered metallic components, a method for producing the precursor and the production of the components. The object of the invention is to disclose possibilities of being able to produce sintered metallic components, wh... | 09/22/2011 |
| 20110215310 | ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME A compound represented by the following Formula (1) is useful as an electron transport material of an organic EL device, and an organic EL device comprising the compound in the electron transport layer is long in life, and low in drive voltage: 09/08/2011 |
