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Class 544/271 - Having -C(=X)-, wherein X is chalcogen attached directly or indirectly to the purine ring system by nonionic bonding or halogen bonded directly at 8-position (e.g., theophylline acetate, 8-chlorotheophylline, etc.)


Subclass of Class 544 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein either a group, in which X is chalcogen
No. of applications: 13
Last issue date: 09/22/2011


Application No.Application TitleIssue Date
20110230479NEUROTROPHIN MIMETICS AND USES THEREOF
The present application is related to compounds which are novel neurotrophin mimetics. The application also discloses the treatment of disorders associated with p75 expression, such as degradation or dysfunction of cells expressing p75 in a mammal by administering an ef...
09/22/2011
20110144095Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
The present invention relates to substituted xanthines of general formula

wherein R1 to R4 are as defined herein, the tautomers and the stereoisomers thereof, mixtures thereof, the prodr...

06/16/2011
20110059995SUBSTITUTED XANTHINE DERIVATIVES
This invention relates to novel compounds that are substituted xanthine derivatives and pharmaceutically acceptable salts thereof. For example, this invention relates to novel substituted xanthine derivatives that are derivatives of pentoxifylline. This invention also p...
03/10/2011
20100228015PRODRUG DERIVATIVES OF ACIDS USING ALCOHOLS WITH HOMOTOPIC HYDROXY GROUPS AND METHODS FOR THEIR PREPARATION AND USE
This invention relates to novel homotopic prodrugs and medicaments and methods for their preparation, testing and use. In one embodiment, the homotopic prodrug has the general formula

wherein

09/09/2010

20100210598TOLL-LIKE RECEPTOR MODULATORS AND TREATMENT OF DISEASES
Provided herein are small molecule conjugates that are agonists or antagonists of one or more toll-like receptors....
08/19/2010
20100204250Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
The present invention relates to substituted xanthines of general formula

wherein R1 to R4 are as defined herein, the tautomers and the stereoisomers thereof, mixtures thereof, the prodr...

08/12/2010
20100190746QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides quinazolinone, compositions and methods th...
07/29/2010
20090239886Substituted xanthine derivatives
This invention relates to novel compounds that are substituted xanthine derivatives and pharmaceutically acceptable salts thereof. For example, this invention relates to novel substituted xanthine derivatives that are derivatives of pentoxifylline. This invention also p...
09/24/2009
20090221821ADENOSINE RECEPTOR ANTAGONISTS AND METHODS OF MAKING AND USING THE SAME
The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A1 receptor. Adenosine A1 antagonists can be useful in the prevention and/or treatment of numerous diseases...
09/03/2009
200802490898-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS
The present invention relates to substituted xanthines of general formula

wherein R1 to R3 are defined as in claims 1 to 16, the tautomers, the stereoisomers, the mixtures,...

10/09/2008
20070287837Radiosynthesis of Acid Chlorides
Radiolabelled acid chlorides may be synthesised by reacting a radiolabelled carboxylic acid with a solid-phase supported chlorinating agent. ...
12/13/2007
20070093659Piperdine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication
The present invention concerns piperidine-amino-benzimidazoles having inhibitory activity on the replication of the respiratory syncytial virus and having the formula
their prodrugs, N-oxides, addition salts, quaternary amines, metal complexes and stereochemic...
04/26/2007
20060211713Compounds having selective hydrolytic potentials
Disclosed are compounds having selective hydrolytic potential. The disclosed compounds are useful as compounds having selective stability and are capable of undergoing programmed hydrolysis in biologic systems. ...
09/21/2006
 
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