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Class 536/51 - Dextran derivatives


Subclass of Class 536 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which are high molecular weight polysaccharides
No. of applications: 19
Last issue date: 02/16/2012


Application No.Application TitleIssue Date
20120041079DEXTRAN FUNCTIONALIZED BY HYDROPHOBIC AMINO ACIDS
Dextran of the following general formula I:

is described, wherein

02/16/2012
20110294118WATER SOLUBLE FLUORESCENT COMPOUNDS
The invention provides a novel class of fluorescent compounds. Also provided are conjugates of the fluorescent compounds, methods of using the fluorescent compounds and their conjugates as well as kits including the fluorescent compounds and their conjugates....
12/01/2011
20110275565BIOCOMPATIBLE POLYSACCHARIDE-BASED HYDROGELS
Modified polysaccharides and crosslinked modified polysaccharide compositions are described. Methods of using the crosslinked modified polysaccharide compositions to deliver proteins, oligonucleotides, or pharmaceutical agents are also disclosed....
11/10/2011
20110195913Anionic polysaccharides functionalized by at least two hydrophobic groups carried by an at least trivalent spacer
Anionic polysaccharide derivatives partially functionalized by at least two vicinal hydrophobic groups, the hydrophobic groups, which are identical or different, being carried by an at least trivalent radical or spacer, a method of synthesis of the functionalized polysa...
08/11/2011
20110171678MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES
Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are u...
07/14/2011
20110118207MODIFIED HYDROXYPOLYMER CONJUGATES WITH BONE SEEKING AND TUMOR KILLING MOIETIES
The present invention is related to a modified hydroxypolymer conjugate, preferably a dextran-guanidine-biphosphonate conjugate for treating not only skeletal tumors i.e. bone metastasis, particularly bone metastasis related to hormone refractory prostate cancer HRPC an...
05/19/2011
20110052732MINERAL ABSORPTION ACCELERATOR AND IRON DEFICIENCY ANEMIA IMPROVER OF FOOD COMPOSITION
A mineral absorption accelerator, and an anemia improving agent, food and drink or food and drink material containing the mineral absorption accelerator are provided, the mineral absorption accelerator including: an α-glucosidase inhibitory component....
03/03/2011
20110041725ANTICOAGULANTS AS ANTIFOULING AGENTS
Methods and compositions are provided for the reduction of fouling of objects present in marine environments. The methods and compositions include anticoagulants, such as, for example, glycosaminoglycans, coumarin-type molecules, metal chelators, plasminogen activators ...
02/24/2011
20110027191OPTICAL IMAGING AGENT
The near-infrared wavelengths (700 nm-900 nm) are a suitable optical window for light penetration and deep tissue imaging. The present invention provides a near-infrared fluorescent blood pool contrast agent. The agent is of use to detect and quantify pathological capil...
02/03/2011
20110003362Conjugates of biological substances
Chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3′-position, their bioconjugates and their uses are described. 1,3′-crosslinked carbocyanines are superior to those of conjugates of spectrally similar 1,1′-cros...
01/06/2011
20100311654Modified Polysaccharide-Based Delivery of Nucleic Acids
The present disclosure provides compositions for enhanced delivery of therapeutic agents. Drug delivery vehicle compositions may include a modified polysaccharide (e.g. chitosan) having at least one secondary amine or at least one tertiary amine and a therapeutic agent ...
12/09/2010
20100272761SYNTHESIS OF LIPOAMIDE-GRAFTED HIGH MOLECULAR COMPOUND AND METHOD THEREFOR
The present disclosure provides polymer compounds binding with lipoamide produced by the reaction of the primary amine group of lipoamide with the carboxy group of polysaccharide compounds such as chondroitin sulfates, carboxymethyl celluloses, or hyaluronic acids; func...
10/28/2010
20100166695Multivalent Heterobifunctional Polymers And Methods Of Their Use
Designed herein are multivalent heterobifunctional polymers for binding to a biological target exhibiting biological activity and to an effector template which can affect the biological activity of the biological target or detect the presence of the biological target. T...
07/01/2010
20100055184HYDROGELS FOR VOCAL CORD AND SOFT TISSUE AUGMENTATION AND REPAIR
The present invention provides hydrogels and compositions thereof for vocal cord repair or augmentation, as well as other soft tissue repair or augmentation (e.g., bladder neck augmentation, dermal fillers, breast implants, intervertebral disks, muscle-mass). The hydrog...
03/04/2010
20080234227Dextran functionalized by hydrophobic amino acids
The invention relates to a dextran functionalized by at least one hydrophobic alpha-amino acid radical, said alpha-amino acid being grafted or bonded to the dextran by a bonding arm and a functional group. A hydrophobic amino acid radical is understood as being the prod...
09/25/2008
20080221066MODIFIED HYDROXYPOLYMER CONJUGATES WITH KILLING EFFECT ON TUMOR CELLS
The present invention is related to a modified hydroxypolymer conjugates preferably a guanidine-dextran conjugate having a tumor cell killing activity. The modified hydroxypolymer conjugate is used as medicine, particularly for manufacturing a medicine or tumor killing ...
09/11/2008
20080014250Bifunctionalized polysaccharides
The present invention relates to a dextran and/or dextran derivative bifunctionalized by at least one imidazolyl radical Im and at least one hydrophobic group Hy, the said radical and the said group being each identical and/or different and grafted or bonded to the dext...
01/17/2008
20070213258Endotoxin adsorbent, and method for removing endotoxin using the same
[OBJECT] The present invention provides a method for selecting and eliminating endotoxin selectively from a solution where a highly acidic substance such as heparin co-exists, and an adsorbent used therefor.

[MEANS FOR SOLVING] The present...

09/13/2007
20060134711Methamphetamine derivatives and conjugates for immunoassay
Compounds of methamphetamine derivatives having a meta-substituted alkyl linker on the benzene ring and a protective group on the nitrogen of the methamphetamine hapten. Such compounds have the structure
wherein R1 is an alkyl linker comprising 2-15...
06/22/2006
 
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