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| Application No. | Application Title | Issue Date |
| 20120129800 | Agent For Preventing And Treating Pityriasis Versicolor The present invention concerns an agent for prevention and treatment of pityriasis. The agent according to the present invention comprises at least one transaminase inhibitor effectively inhibiting the transamination process which is of pat... | 05/24/2012 |
| 20120071424 | PHARMACEUTICAL COMPOSITION USED IN PROPHYLAXIS OR TREATMENT OF HYPERPROLIFERATIVE SKIN CONDITIONS AND MALIGNANT MELANOMAS COMPRISING PACHASTRISSAMINE AS ACTIVE INGREDIENT Disclosed is a novel use of phytosphingosine. More particularly, disclosed are a composition for preventing or treating hyper-proliferative skin diseases comprising pachastrissamine as an active ingredient, a use of pachastrissamine or a pharmaceutically acceptable salt... | 03/22/2012 |
| 20120046737 | MEDICAL DEVICES HAVING ACTIVATED SURFACES Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.... | 02/23/2012 |
| 20120035340 | AMINATED HEMICELLULOSE MOLECULE AND METHOD FOR PRODUCTION THEREOF The present invention relates to a method for reductive amination of a water soluble carbohydrate. An aminated water soluble carbohydrate is a prerequisite in processes for further modification of cellulose. The synthesis of this molecule comprises, providing a water so... | 02/09/2012 |
| 20120027857 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING O-DESMETHYL-VENLAFAXINE This invention relates to sustained release pharmaceutical compositions comprising O-desmethyl-venlafaxine, in particular to sustained pharmaceutical compositions comprising O-desmethyl-venlafaxine orotate and/or O-desmethyl-venlafaxine glucuronate.... | 02/02/2012 |
| 20120014923 | HYPOGLYCEMIC EFFECT ENHANCER A hypoglycemic effect enhancer for enhancing the activity of an α-glucosidase inhibitor, the enhancer comprising at least one kind of bacteria selected from the group consisting of bifidobacteria, lactic acid bacteria, saccharifying bacteria, and butyric acid bacteria.... | 01/19/2012 |
| 20110301104 | Transition state structure of orotate phosphoribosyl transferases and uses thereof Methods are provided for designing a transition state inhibitor of orotate phosphoribosyltransferase (OPRT) and for inhibiting OPRT.... | 12/08/2011 |
| 20110301083 | CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY Conjugates which comprise a drug and a ligand which includes a first saccharide; wherein the conjugate is characterized in that, when the conjugate is administered to a mammal, at least one pharmacokinetic or pharmacodynamic property of the conjugate is sensitive to ser... | 12/08/2011 |
| 20110274672 | SIALIC ACID PRODUCING BACTERIA The present invention generally relates to the field of sialic acids, in particular to the field of sialic acid enriched food products and their uses. One embodiment of the present invention relates to a food product enriched with food-grade sialic acid producing bacter... | 11/10/2011 |
| 20110269700 | GLUCOSIDE DERIVATIVES AND USES THEREOF The present invention relates to compounds of formula I and pharmaceutically acceptable salts thereof, and to formulations and uses of the compounds of formula (I) in the treatment of metabolic disorders.... | 11/03/2011 |
| 20110237529 | Adenosine Analogs and Their Use The invention provides adenosine analog compounds that act at P2Y receptors, e.g., the P2Y2 receptor, including pharmaceutical compositions; and uses thereof to treat or prevent diseases associated with that receptor, e.g., disorders relating to mucus secreti... | 09/29/2011 |
| 20110237785 | SPATIALLY-DEFINED MACROCYCLIC COMPOUNDS USEFUL FOR DRUG DISCOVERY Novel spatially-defined macrocyclic compounds containing specific conformational control elements are disclosed. Libraries of these macrocycles are then used to select one or more macrocycle species that exhibit a specific interaction with a particular biological target... | 09/29/2011 |
| 20110230428 | CERTAIN KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF Certain chemical entities are provided herein. Pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibitio... | 09/22/2011 |
| 20110218331 | Method of Preparation of DTPA Crosslinked Hyaluronic Acid Derivatives and Modification of Said Dervivatives The invention relates to the modification of hyaluronic acid by means of a protonized DTPA bis anhydride in a non-basic polar aprotic solvent in absence of any external base to form crosslinked products. The reaction runs via the formation of a complex and the acylating... | 09/08/2011 |
| 20110212904 | GALACTOSYLATED PRO-DRUGS OF NON-STEROIDAL ANTI-INFLAMMATORIES WITH IMPROVED PHARMACOKINETIC CHARACTERISTICS AND REDUCED TOXICITY OF THE STARTING DRUG Pro-drugs of all non-steroidal anti-inflammatories with free acid function derivatized with an ester group, which have the general structural formula given below (I) where A is: aspirin, diflunisal, benorylate, ibufenac, diclofenac, indomethacin, sulindac, ketorolac, ib... | 09/01/2011 |
| 20110190481 | EXTRACTION METHOD FOR SIALIC ACID-CONTAINING COMPOUND FROM PLANT An object of the present invention is to provide an inexpensive and simple extraction method for a sialic acid-containing compound from a raw material which is easily available and has no risk of contamination with pathogens affecting animals (raw material which has hig... | 08/04/2011 |
| 20110178033 | GLUCOPYRANOSYL-SUBSTITUTED PHENYL DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE Glucopyranosyl-substituted benzene derivatives of general formula I where the groups R1 to R6 as well as R7a, R7b, R7c are defined herein and the tautome... | 07/21/2011 |
| 20110177004 | Version of FDG Detectable by Single-Photon Emission Computed Tomography A compound comprising a metal chelate linked to a hexose carrier for use as a metallopharmaceutical diagnostic or therapeutic agent is provided. The compound is suitable for imaging by single-photon emission computed tomography, computer assisted tomography, magnetic re... | 07/21/2011 |
| 20110171159 | Glycoside Derivatives and Uses Thereof This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-tra... | 07/14/2011 |
| 20110159517 | Zinc binding compounds and their method of use The present invention provides a metal chelator and methods that facilitate binding, detecting, monitoring and quantitating of zinc ions in a sample. The metal chelating moiety of the zinc-binding compound is an analog of the well-known calcium chelator, BAPTA (1,2-bis(... | 06/30/2011 |
| 20110144317 | MUTANTS OF GLYCOSIDE HYDROLASES AND USES THEREOF FOR SYNTHESIZING COMPLEX OLIGOSACCHARIDES AND DISACCHARIDE INTERMEDIATES Method for preparing the disaccharide [α-D-Gldp(1→3)]-α-L-Rhap-YR wherein Y is selected from —O— and —S— and R is selected from the group consisting of: C1-C6 alkyl, C1-C6 alkenyl, aryl, allyl, —CO-alkyl (C1... | 06/16/2011 |
| 20110129544 | Bone/Cartilage Formation-Stimulation Agent Disclosed is a mixture of: a bone/cartilage formation promoting agent containing sulfated galactosaminoglycan having greater than or equal to 0.6 numbers of ester sulfate groups on average per constituent monosaccharide or a salt thereof as an active ingredient; a facto... | 06/02/2011 |
| 20110124573 | Osmoprotective Complexes for Prevention of Intra-cellular Dehydration in Mammals This invention relates to certain Aloesin derivatives with natural amino acids, peptides, and amino sugars (formula I). The compounds of the present invention possess osmoprotective properties, which are suitable for topical or oral application to treat dermatological d... | 05/26/2011 |
| 20110112282 | IDO INHIBITORS AND THERAPEUTIC USES THEREOF Compounds of formula (I), and pharmaceutically acceptable salts thereof, in which each compound is adapted to occupy the binding site of human IDO, which comprises a large hydrophobic pocket A and a second, proximal hydrophobic pocket B, the compound comprising at least... | 05/12/2011 |
| 20110104076 | Compositions, Methods For Preparing Amino Acids And Nuclear Magnetic Resonance Spectroscopy The present invention relates to amino acids, complexes, and compounds comprising deuterium and tritium isotopes preferably alpha deuterated amino acids, polypeptides, antibodies, derivatives and saccharide-amino acid complexes and conjugates. In some embodiments, the i... | 05/05/2011 |
| 20110077193 | Artemisinin Derivatives with Natural Amino Acids, Peptides, and Amino Sugars for the Treatment of Infection and Topical Condition in Mammals The present invention discloses certain derivatives of artemisinin and the active principles contained in Artemisia annua extracts with amino acids, peptides, and amino sugars, and isomers and salts thereof (formula I). The compounds of the present invention possess wid... | 03/31/2011 |
| 20110077216 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ATHEROSCLEROSIS AND OTHER RELATED DISEASES The present invention provides compositions and methods for the treatment of atherosclerosis and other related diseases. In some embodiments, a method comprises providing a composition and forming a coating of the composition on at least a portion of the interior and/or... | 03/31/2011 |
| 20110059910 | Novel aromatic fluoroglycoside derivatives, pharmaceuticals comprising said compounds and the use thereof The invention relates to substituted aromatic fluoroglycoside derivatives, and to the physiologically compatible salts and physiologically functional derivatives thereof. The invention also relates to methods of lowering blood sugar and the treatment of type I and type ... | 03/10/2011 |
| 20110045585 | Kit for fluorometric analysis Chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3′-position, their bioconjugates and their uses are described. 1,3′-crosslinked carbocyanines are superior to those of conjugates of spectrally similar 1,1′-cros... | 02/24/2011 |
| 20110040084 | METHOD FOR EXTRACTING SIALIC ACID-CONTAINING COMPOUND FROM PLANT It is an object of the present invention to provide an extraction method for a sialic acid-containing compound from a natural raw material, which has no risk of contamination with pathogens affecting animals, can achieve mass production, and does not require the use of ... | 02/17/2011 |
| 20110034413 | NOVEL QUERCETIN DERIVATIVES AS ANTI-CANCER AGENTS The present invention provides novel Quercetin derivatives of formula (I) and pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1 is hydrogen, benzyl or substituted benzyl... | 02/10/2011 |
| 20100331274 | Antiaging Chirally-Correct Mitoprotectant Amino Acid and Peptide Complexes This invention relates to certain chirally-correct mitoprotectant phosphorylated heterocyclic agents [formula (I)], which are useful for the treatment of dermatological disorders that include challenged skin from cancer, diabetes, radiation treatments, chemotherapy, and... | 12/30/2010 |
| 20100322958 | MODIFIED SACCHARIDES Modified capsular saccharides comprising a blocking group at a hydroxyl group position on at least one of the monosaccharide units of the corresponding native capsular saccharide, wherein the blocking group is of the formula (Ia) or (Ib): —OX—Y (Ia) or —O—R... | 12/23/2010 |
| 20100324123 | GLMS RIBOSWITCHES, STRUCTURE-BASED COMPOUND DESIGN WITH GLMS RIBOSWITCHES, AND METHODS AND COMPOSITIONS FOR USE OF AND WITH GLMS RIBOSWITCHES The glmS riboswitch is a target for antibiotics and other small molecule therapies. Compounds can be used to stimulate, active, inhibit and/or inactivate the glmS riboswitch. The atomic structures of the glmS riboswitch can be used to design new compounds to stimulate, ... | 12/23/2010 |
| 20100273994 | HYBRID COMPOUNDS CONTAINING POLYSACCHARIDE(S) AND AT LEAST ONE POLYOXYALKYLENE, METHOD FOR PREPARING SAME, AND APPLICATIONS THEREOF The invention relates to novel hybrid compounds containing at least one polysaccharide entity (PS), such as guar, in which at least one hydroxyl function is substituted by at least one A polyoxyalkylene entity (PEG). The swivel Ro between the entity PS and the entity A ... | 10/28/2010 |
| 20100260762 | De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy The present invention generally provides compositions methods and composition relating to the diagnosis and/or treatment of cancers having a cell surface de-N-acetylated sialic acid antigen, e.g., an at least partially de-N-acetylated ganglioside and/or a de-N-acetylate... | 10/14/2010 |
| 20100240773 | MULTIFUNCTIONAL LINKERS The present invention relates generally to multifunctional polymeric linkers capable of linking a plurality of biologically active compounds. More particularly, the invention relates to the use of such multifunctional linkers that can effectively present two or more lig... | 09/23/2010 |
| 20100234258 | AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT The present invention relates to a product of reaction between a primary and/or secondary amine and one or more active ingredients. By the present invention, there is provided a release of the active component over a longer period of time than by the use of the active i... | 09/16/2010 |
| 20100160251 | IMIDAZO COMPOUNDS The present invention relates to the use of at least one lactose-derived C-glycoside of general formula (I): as an agent for protecting and/or stimulating the activity and/or the proliferation of gamma-delta ... | 06/24/2010 |
| 20100144045 | CHIRAL SELECTORS FOR SEPARATING ENANTIOMERS OF A COMPOUND The invention relates to the use of compounds as new chiral selectors for separating the optical or enantiomeric isomers of a compound, wherein the chiral selector comprises at least one compound of formula (I): and at least one metal ion, for example Cu2+, N... | 06/10/2010 |
