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...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Application No. | Application Title | Issue Date |
| 20120108801 | DISUBSTITUTED-AMINODIFLUOROSULFINIUM SALTS, PROCESS FOR PREPARING SAME AND METHOD OF USE AS DEOXOFLUORINATION REAGENTS The invention relates to disubstituted-aminodifluorosulfinium salts represented by the formula (I). Processes for preparing same and methods of use as deoxofluorinating reagent is also provided. ... | 05/03/2012 |
| 20110251068 | PARASITIC PLANT CONTROL AGENT AND PARASITIC PLANT CONTROL METHOD Disclosed is a parasitic plant control agent which can control a parasitic plant effectively. Also disclosed is a parasitic plant control method. A parasitic plant can be controlled by inhibiting the metabolism of gentianose in the parasitic plant to inhibit the germina... | 10/13/2011 |
| 20110237657 | Transport-Mediating Colloidal Pharmaceutical Compounds The invention relates to transport mediator-bonded colloids comprising pharmaceutical substances or fluorescence markers, to a method for the production thereof, and to a pharmaceutical preparation comprising said compounds.... | 09/29/2011 |
| 20110218159 | METHODS OF USING INHIBITORS OF SODIUM-GLUCOSE COTRANSPORTERS 1 AND 2 Methods of improving the cardiovascular and/or metabolic health of patients, particularly those suffering from type 2 diabetes, are disclosed, as well as compounds and pharmaceutical compositions useful therein.... | 09/08/2011 |
| 20110201795 | Methods of Producing C-Aryl Glucoside SGLT2 Inhibitors Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents.... | 08/18/2011 |
| 20110172176 | CRYSTAL STRUCTURES OF SGLT2 INHIBITORS AND PROCESSES FOR PREPARING SAME The present invention relates to physical crystal structures of a compound of the formula I: wherein R1, R2, R2a, R3 and R4 are as defined herein, especi... | 07/14/2011 |
| 20110059910 | Novel aromatic fluoroglycoside derivatives, pharmaceuticals comprising said compounds and the use thereof The invention relates to substituted aromatic fluoroglycoside derivatives, and to the physiologically compatible salts and physiologically functional derivatives thereof. The invention also relates to methods of lowering blood sugar and the treatment of type I and type ... | 03/10/2011 |
| 20110003981 | PROCESS FOR PRODUCING RADIOACTIVE FLUORINE LABELED ORGANIC COMPOUND, AND RELEVANT SYNTHETIC APPARATUS AND PROGRAM A method of producing a radioactive-fluorine-labeled compound has a step of heating in a reaction vessel a mixture containing [18F] fluoride ions, a phase transfer catalyst, potassium ions, and water to evaporate water from the mixture (S10), and in th... | 01/06/2011 |
| 20100311673 | SULFANYL-TETRAHYDROPYRAN-BASED COMPOUNDS AND METHODS OF THEIR USE Sulfanyl-tetrahydropyran-based compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment of diseases and disorders such as diabetes and obesity are disclosed.... | 12/09/2010 |
| 20100298550 | PROCESS FOR PRODUCTION OF RIBOFURANOSE DERIVATIVES It is an object of the present invention to provide a process for producing 1,2,3-tri-O-acetyl-5-deoxy-ribofuranose in an industrially appropriate manner. The present invention provides a process for producing a 1,2,3-tri-O-acetyl-5-deoxy-ribofuranose which comprises hy... | 11/25/2010 |
| 20100261664 | Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof The invention relates to substituted heterocyclic fluoroglycoside derivatives of the formula I <... | 10/14/2010 |
| 20100152125 | Compositions And Methods For The Diagnosis, Treatment, And Prevention Of Amyotrophic Lateral Sclerosis And Related Neurological Diseases One aspect of the invention relates to a method of treating or preventing a neurodegenerative disease, comprising the step of administering to a patient in need thereof a therapeutically effective amount of an inhibitor of the formation of advanced glycation end product... | 06/17/2010 |
| 20090281294 | PROCESS FOR PRODUCTION OF COMPOUND LABELED WITH RADIOACTIVE FLUORINE A process for the production of [18F]-TAFDG can produce [18F]-TAFDG in a high radiofluorination yield. A process for the production of an organic compound labeled with radioactive fluorine includes the steps of preparing a reaction solution contain... | 11/12/2009 |
| 20090281295 | CRYSTALLIZATION OF SUCRALOSE FROM SUCRALOSE-CONTAINING FEED STREAMS A process for the purification of sucralose in sucralose-containing feed streams is disclosed. The process includes multiple liquid-liquid extraction steps; optionally, a concentration step; multiple crystallization steps; optionally, a chromatography step; and various ... | 11/12/2009 |
| 20090156516 | BENZYLPHENYL CYCLOHEXANE DERIVATIVES AND METHODS OF USE Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or ... | 06/18/2009 |
| 20090095936 | Fluoroalkenyl Poly[1,6]glycosides Fire extinguishing compositions and methods of extinguishing a fire comprising compounds of formula (I) where Rf is a fluorocarbon group. The compounds and compositions described herein are useful as intermediates in the preparation of or as additives to AFFF... | 04/16/2009 |
| 20080300391 | Acid Mediated Deacylation of 6-0-Trichlorogalactosurcrose to Trich-Lorogalactosucrose A process is described for acid mediated deacylation of acyl derivatives of chlorinated sucrose compounds comprising generating a predominantly organic phase condition in a process stream requiring deacylation treatment but allowing an optimum quantity of water content ... | 12/04/2008 |
| 20080221312 | METHOD FOR CRYSTALLIZING SUCRALOSE The present application discloses a method for crystallizing sucralose, which uses an alcohol solvent or a mixed solvent of alcohol and other solvent(s) in the crystallization of sucralose.... | 09/11/2008 |
| 20080221313 | PROCESS FOR THE PREPARATION OF SUCRALOSE BY THE DEACYLATION OF TRICHLOROSUCROSE-6-ETHYL ESTER The present invention discloses a process for the preparation of sucralose by the deacylation of trichlorosucrose-6-ethyl ester, wherein the deacylation reaction is performed in an alcohol solvent in the presence of organic base catalyst, so as to obtain sucralose.... | 09/11/2008 |
| 20080108580 | NOVEL AROMATIC FLUOROGLYCOSIDE DERIVATIVES, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF Novel aromatic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof. The invention relates to substituted aromatic fluoroglycoside derivatives of the formula I in which the radicals have the stated meanings, and their physio... | 05/08/2008 |
| 20080103295 | PROCESS FOR THE PREPARATION OF SUCROSE-6-ESTER BY ESTERIFICATION IN THE PRESENCE OF SOLID SUPERACID CATALYST One embodiment of the present invention is a process of making sucrose-6-ester from sucrose by transesterification in the presence of a solid super acid catalyst such as SO42−—TiO2/Al2O3 or SO42â... | 05/01/2008 |
| 20070238866 | METHODS OF PRODUCING C-ARYL GLUCOSIDE SGLT2 INHIBITORS Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents. ... | 10/11/2007 |
| 20070238865 | 1-Alpha-Halo-2,2-Difluoro-2-Deoxy-D-Ribofuranose Derivatives and Process for the Preparation Thereof 1-α-halo-2,2-difluoro-2-deoxy-D-ribofuranose derivative of formula (I) having the 3-hydroxy group protected with a biphenylcarbonyl group is a solid which can be easily purified by a simple procedure such as recrystallization, and therefore, it can be advantageously us... | 10/11/2007 |
