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| Application No. | Application Title | Issue Date |
| 20120129793 | Antimicrobial Polyether and Polyol Compounds The present application describes compounds of Formula I and Formula IA and as disclosed herein, that are useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents.... | 05/24/2012 |
| 20120071647 | Microfluidic reactor having an annular reaction chamber A microfluidic reactor has a reaction chamber which is configured as an annular channel. It is provided that segments have been formed in the annular channel such that a sequence of inlets and outlets (allows an alternation between the process fluids (A and B) to take p... | 03/22/2012 |
| 20120029183 | SULFATED C-GLYCOSIDE, METHOD FOR ISOLATING SAME AND METHOD FOR SYNTHESIZING SAME Provided are a sulfated C-glycoside which is a novel compound serving as a precursor of chafuroside and chafuroside analogs; a method for efficiently producing the sulfated C-glycoside; and a method for efficiently producing chafuroside and chafuroside analogs using sai... | 02/02/2012 |
| 20110301119 | PHARMACEUTICAL COMPOSITIONS CONTAINING FUCOIDAN FOR STIMULATING AND ACTIVATING OSTEOGENESIS The present invention relates to pharmaceutical compositions containing fucoidan for stimulating and activating osteogenesis. The compositions according to the present invention contain fucoidan as an active ingredient to increase the activities of alkaline phosphatase ... | 12/08/2011 |
| 20110288287 | Halogen Substituted Saccharide, Method for Producing Same, Reaction Composition of Same and Device for Producing Same The present invention provides: a method for synthesizing a halogen-substituted saccharide from a leaving group-substituted saccharide in a short-time and continuously; a reaction composition; and a device for synthesis of same, i.e., the method being for synthesizing a... | 11/24/2011 |
| 20110280829 | Low Molecular Weight Sulphated Polysaccharides as Candidates for Anti-Angiogenic Therapy Low molecular weight sulphated L-fucose polysaccharide fraction having a molecular weight ranging from 11 to 30 kDa when measured with TEST A, a sulphate content ranging from 10 and 50% w/w relative to the total weight of the fraction, a fucosis content ranging from 30 ... | 11/17/2011 |
| 20110263527 | Sulfated Galactans With Antithrombotic Activity, Pharmaceutical Composition, Method for Treating or Prophylaxis of Arterial or Venous Thrombosis, Method of Extraction and Use Thereof The present invention relates to low molecular weight sulfated galactans, obtained from algae, particularly genus Botryocladia, preferably species Botryocladia occidentallis, which have no effect on the factor XII activation of the clotting cascade, having... | 10/27/2011 |
| 20110244478 | Methods and Compositions for Treating Bleeding Disorders Aspects of the invention include methods for enhancing blood coagulation in a subject. In practicing methods according to certain embodiments, an amount of a non-anticoagulant sulfated polysaccharide (NASP) is administered to a subject to enhance blood coagulation in th... | 10/06/2011 |
| 20110212905 | CRYSTALLINE FORM OF 1-(BETA-D-GLUCOPYRANOSYL)-4-METHYL-3-[5-(4-FLUOROPHENYL)-2-THIENYLMETHYL]BENZENE HEMIHYDRATE A novel crystal form of 1-(β-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene hemihydrate, and having favorable characteristics, is characterized by its x-ray powder diffraction pattern and/or by its infra-red spectrum.... | 09/01/2011 |
| 20110212914 | STABILIZED PENTOSAN POLYSULFATE (PPS) FORMULATIONS AND METHODS OF ANALYZING THEM Various pentosan polysulfate (PPS) formulations useful for treatment of osteoarthritis, interstitial cystitis, and other conditions of mammals are provided. These formulations showed improved resistance to degradation and discoloration and improved stability at physiolo... | 09/01/2011 |
| 20110207921 | SULFATED DERIVATIVE OF GASTRODIA ELATA POLYSACCHARIDE, PREPARATION METHOD AND ANTITUMOR USE THEREOF The present invention discloses a sulfated derivative of polysaccharide extracted from gastrodia elata BL., the preparation method thereof and the use thereof in preparing antineoplastic medicaments, wherein, the gastrodia elata polysaccharide has the foll... | 08/25/2011 |
| 20110201795 | Methods of Producing C-Aryl Glucoside SGLT2 Inhibitors Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents.... | 08/18/2011 |
| 20110178033 | GLUCOPYRANOSYL-SUBSTITUTED PHENYL DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE Glucopyranosyl-substituted benzene derivatives of general formula I where the groups R1 to R6 as well as R7a, R7b, R7c are defined herein and the tautome... | 07/21/2011 |
| 20110171159 | Glycoside Derivatives and Uses Thereof This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-tra... | 07/14/2011 |
| 20110172156 | METHODS AND COMPOSITIONS FOR TREATING BLEEDING DISORDERS Aspects of the invention include methods for enhancing blood coagulation in a subject. In practicing methods according to certain embodiments, an amount of a non-anticoagulant sulfated polysaccharide (NASP) is administered to a subject to enhance blood coagulation in th... | 07/14/2011 |
| 20110098465 | Nonflow -Through Apparatus And Method Using Enhanced Flow Mechanisms Methods and apparatus for facilitating the synthesis of compounds in a nonflow-through device are presented. Application of the nonflow-through methods and microfluidic devices to the synthesis of radiolabeled compounds is described. These methods and apparatus enable t... | 04/28/2011 |
| 20110087019 | Process for the production of sucrose-6-ester A process for the production of sucrose-6-ester is disclosed. The process includes, in order, the steps of:
| 04/14/2011 |
| 20110087018 | Low Temperature, Single Solvent Process for the Production of Sucrose-6-Ester A method for the preparation of a sucrose-6-ester is disclosed. In a first step of the method, sucrose in a polar aprotic solvent is reacted with an organotin-based acylation promoter. The water of reaction is removed at a temperature that does not exceed about 80° C. ... | 04/14/2011 |
| 20110087017 | PROCESS FOR THE PREPARATION OF COMPOUNDS USEFUL AS INHIBITORS OF SGLT2 The present invention is directed to a novel process for the preparation of compounds having inhibitory activity against sodium-dependent glucose transporter (SGLT) being present in the intestine or kidney.... | 04/14/2011 |
| 20110059910 | Novel aromatic fluoroglycoside derivatives, pharmaceuticals comprising said compounds and the use thereof The invention relates to substituted aromatic fluoroglycoside derivatives, and to the physiologically compatible salts and physiologically functional derivatives thereof. The invention also relates to methods of lowering blood sugar and the treatment of type I and type ... | 03/10/2011 |
| 20110059919 | ANTIVIRAL COMPOSITION COMPRISING A SULFATED POLYSACCHARIDE The present invention provides for the use of iota- and/or kappa-carrageenan for the manufacture of an antiviral pharmaceutical composition for the prophylaxis or treatment of a pathological condition or disease caused by or associated with an infection by a respiratory... | 03/10/2011 |
| 20110034402 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY This invention relates to a compound of generic formula (I): (I) as well as a pharmaceutically acceptable salt thereof a tautomer, optical isomer or a mixture of optical isomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixtu... | 02/10/2011 |
| 20100322858 | Radiohaloimatinibs and Methods of Their Synthesis and Use in PET Imaging of Cancers We disclose methods of synthesizing radiohalidated organic compounds and their use in positron emission tomography (PET) imaging of cancer cells.... | 12/23/2010 |
| 20100298550 | PROCESS FOR PRODUCTION OF RIBOFURANOSE DERIVATIVES It is an object of the present invention to provide a process for producing 1,2,3-tri-O-acetyl-5-deoxy-ribofuranose in an industrially appropriate manner. The present invention provides a process for producing a 1,2,3-tri-O-acetyl-5-deoxy-ribofuranose which comprises hy... | 11/25/2010 |
| 20100297124 | INDUCED INTERNALIZATION OF SURFACE RECEPTORS Disclosed is a hetero-bifunctional ligand for use in inducing internalization of a target receptor. The hetero-bifunctional ligand includes a target receptor-binding agent that specifically binds the target receptor linked to an internalizing receptor-binding agent that... | 11/25/2010 |
| 20100291547 | FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS The present disclosure is directed to fluorogenic schiff base-forming dyes capable of detecting analytes containing aldehyde and ketone groups. The dyes contain nucleophilic hydrazinyl appendages and are capable of binding and detecting analytes in situ.... | 11/18/2010 |
| 20100290988 | FLUORINATED FRUCTOSE DERIVATIVES FOR PET IMAGING The present invention is directed to fructose-based radiopharmaceuticals, pharmaceutical compositions comprising same, precursors and methods for preparing same, and methods of using same for diagnostic imaging of cancer cells and non-imaging tracer studies.... | 11/18/2010 |
| 20100285570 | FLUORIDE PROCESSING METHOD The invention relates to methods for processing [18F]-fluoride target water using a solid-support bound Cryptand of formula (I) and to apparatus for performing such methods. The resultant [18F]-fluoride is useful for preparation of radiopharmaceuti... | 11/11/2010 |
| 20100280177 | MULTICOMPONENT ASSEMBLIES HAVING ENHANCED BINDING PROPERTIES FOR DIAGNOSIS AND THERAPY An organized mobile multicomponent conjugate (OMMC) and method of using to enhance binding of weakly binding compounds to a target. A lamellar structure containing at least two binding compounds is assembled under conditions in which the binding compounds self-regulate ... | 11/04/2010 |
| 20100226865 | TOOTHPASTE COMPOSITION A toothpaste composition comprising a surfactant, an abrasive, a humectant, triglyceride oil, a carboxylated polysaccharide, and a sulphated or sulphonated polysaccharide and the use of a sulphated or sulphonated polysaccharide, in particular a carrageenan, to improve t... | 09/09/2010 |
| 20100197906 | Method for purification of chlorinated sucrose derivatives from reaction mixture by chromatography A chromatographic process of DMF removal from an aqueous composition is described comprising its loading on a column of hydrophobic fixed bed adsorbent and eluting out DMF with an aqueous alkaline buffer. This method is useful to remove DMF as a process of general appli... | 08/05/2010 |
| 20100184969 | Process to Prepare Sucralose The present invention relates to a process to prepare sucralose. More particularly the said process relates to the production of sucralose, chemically known as, 6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-alpha-D-galactopyranoside of formula (1) | 07/22/2010 |
| 20100184054 | BINDING OF PATHOLOGICAL FORMS OF PRION PROTEINS A process for the selective binding of an aggregating abnormal form of a protein in the presence of the nonaggregating normal form of the protein, including contacting under selective binding conditions a material containing both the abnormal and normal forms with a bin... | 07/22/2010 |
| 20100184223 | Biomaterial based on a hydrophilic polymeric carrier The present invention relates to a biomaterial for cell or tissue culture, based on a polymeric carrier, which contains at least one crosslinkable hydrophilic polymer. The polymer is functionalized with groups that are selected from maleimide, vinylsulfonic, acrylate, a... | 07/22/2010 |
| 20100184710 | Therapeutic Bifunctional Compounds The invention generally relates to systems and methods for treating inflammatory and proliferative diseases, enabling treatment of MDR tumor cells by using a bifunctional compound that inhibits both fatty acid metabolism and glycolysis. Thus, the invention links a fatty... | 07/22/2010 |
| 20100179314 | Novel and Highly Stereoselective Process for Preparing Gemcitabine and Intermediates Thereof The present invention provides a novel and highly stereoselective process for preparing gemcitabine, which is suitable for industrial production, wherein, it includes the following reactions. Additionally, the invention discloses the key intermediates. The definition fo... | 07/15/2010 |
| 20100166801 | SULFOGLYCOLIPID ANTIGENS, THEIR PROCESS OF PREPARATION, AND THEIR USE AGAINST TUBERCULOSIS The present invention relates to compounds of the following general formula (I) their process of preparation and their use in the treatment or the prophylaxis of tuberculosis.... | 07/01/2010 |
| 20100152121 | Iodo-Hexose Compounds Useful to Treat Cancer Methods of treating glioblastoma and pancreatic cancer are provided by the administration of a therapeutically effective amount of a iodo-hexose compound to a subject in need thereof. The subject disclosure includes methods of treating glioblastoma and pancreatic cancer... | 06/17/2010 |
| 20100113762 | Apparatus and Method Using Rotary Flow Distribution Mechanisms Methods and apparatus for facilitating the synthesis of compounds in a batch device are presented. Application of the batch type microfluidic devices to the synthesis of radiolabeled compounds is described. These methods and apparatus enable the selective introduction o... | 05/06/2010 |
| 20100105889 | PROCESS FOR THE PREPARATION OF PENTOSAN POLYSULFATE OR SALTS THEREOF A process for the preparation of Pentosan polysulfate sodium comprising a step of purifying depolymerized crude Pentosan polysulfate sodium by filtration through NF membrane system.... | 04/29/2010 |
