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Behavior Modification Wristwatch
A wristwatch including a watch band and a watch body having an octagon shaped perimeter and being red in color and having the word STOP thereon to resemble a stop sign.
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| Application No. | Application Title | Issue Date |
| 20120108796 | Optimized Monoclonal Antibodies against Tissue Factor Pathway Inhibitor (TFPI) Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) are provided. Isolated nucleic acid molecules encoding monoclonal antibodies that bind TFPI are also contemplated. Pharmaceutical compositions comprising the anti-TFPI monoclonal antib... | 05/03/2012 |
| 20120082666 | ANTIBODY COMPOSITIONS AND METHODS OF USE The invention provides compositions comprising anti-gH antibodies and anti-Complex I antibodies as well as methods of using the same.... | 04/05/2012 |
| 20120052073 | Antibodies Directed to Angiopoietin-2 And Uses Thereof Antibodies directed to the antigen Ang-2 and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the antigen Ang-2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin m... | 03/01/2012 |
| 20120045442 | HUMAN MONOCLONAL ANTIBODIES TO CTLA-4 In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucelotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, part... | 02/23/2012 |
| 20120045443 | Agonist anti-trk-c monoclonal antibodies The invention concerns agonist anti-trkC monoclonal antibodies which mimic certain biological activities of NT-3, the native ligand of trkC. The invention further concerns the use of such antibodies in the prevention and/or treatment of cellular degeneration, including ... | 02/23/2012 |
| 20120046452 | ANTIBODY-MEDIATED REJECTION INHIBITOR A purpose of the present disclosure to achieve transplantation from ABO-incompatible donors and inhibition of autoimmune disease, for example, without significantly impairing defense mechanisms. An antibody-mediated rejection inhibitor for ... | 02/23/2012 |
| 20120039899 | Anti-Hemagglutinin Antibody Compositions And Methods Of Use Thereof The present invention provides novel human anti-Influenza antibodies and related compositions and methods. These antibodies are used in the prevention, inhibition, neutralization, diagnosis, and treatment of influenza infection.... | 02/16/2012 |
| 20120039898 | HUMAN BINDING MOLECULES CAPABLE OF NEUTRALIZING INFLUENZA VIRUS H3N2 AND USES THEREOF Binding molecules, such as human monoclonal antibodies, that bind to influenza virus comprising HA of the H3 subtype, such as H3N2, and have a broad neutralizing activity against such influenza virus. Provided are nucleic acid molecules encoding the antibodies, their se... | 02/16/2012 |
| 20120039904 | ANTI SYSTEM ASC AMINO ACID TRANSPORTER 2 (ASCT2) ANTIBODY An object of the present invention is to provide a monoclonal antibody which is useful for treating or diagnosing a disease relating to system ASC amino acid transporter 2 (ASCT2) or a method using the antibody. The present invention provides a monoclonal antibody which... | 02/16/2012 |
| 20120039846 | HEPATITIS C ANTIBODIES AND USES THEREOF The present invention provides identification and characterization of conformational epitopes of the envelope protein E2 of the Hepatitis C virus (HCV). The present invention provides a panel of human monoclonal antibodies that recognize conformational epitopes of E2. T... | 02/16/2012 |
| 20120020957 | DENGUE VIRUS NEUTRALIZING ANTIBODIES AND USE THEREOF The invention relates to antibodies and antigen binding fragments thereof and to cocktails of antibodies and antigen binding fragments that neutralize dengue virus infection without contributing to antibody-dependent enhancement of dengue virus infection. The invention ... | 01/26/2012 |
| 20120020971 | ANTIBODIES USEFUL IN PASSIVE INFLUENZA IMMUNIZATION Monoclonal antibodies and fragments thereof that are crossreactive with multiple clades of influenza virus including both Group 1 and Group 2 representatives are disclosed. These antibodies are useful in controlling influenza epidemics and pandemics as well as in provid... | 01/26/2012 |
| 20120020980 | HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN CYTOMEGALOVIRUS (CMV) GB PROTEIN Antibodies to human Cytomegalovirus (CMV) gB protein have been isolated from human B cells. The affinities of these antibodies are higher than the best previously reported antibodies. Since high affinity is critical to prevention of virus transfer across the placenta, t... | 01/26/2012 |
| 20120020981 | Anti-IL6/IL-6R Antibodies and Methods of Use Thereof This invention provides fully human monoclonal antibodies that recognize the IL-6/IL-6R complex. The invention further provides methods of using such monoclonal antibodies as a therapeutic, diagnostic, and prophylactic.... | 01/26/2012 |
| 20120009194 | ANTIBODIES TO ENDOPLASMIN AND THEIR USE Isolated monoclonal antibodies are disclosed herein that specifically bind endoplasmin. In some embodiments these antibodies are fully human. Recombinant nucleic acids encoding these antibodies, expression vectors including these nucleic acids, and host cells transforme... | 01/12/2012 |
| 20120009195 | ANTIBODY NEUTRALIZERS OF HUMAN GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR The present invention relates to a human monoclonal antibody or fragment thereof which specifically binds to and neutralizes primate GM-CSF.... | 01/12/2012 |
| 20120009196 | MONOCLONAL ANTIBODIES AGAINST HEPATITIS C VIRUS CORE PROTEIN The present disclosure relates to anti-HCV core protein monoclonal antibodies, methods of making them, and their uses in the prevention, diagnosis, and/or treatment of disease including HCV infections.... | 01/12/2012 |
| 20120005767 | ANTIBODIES TO INSULIN-LIKE GROWTH FACTOR I RECEPTOR The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to insulin-like growth factor I receptor (IGF-IR), which is preferably human IGF-IR. The invention also relates to human anti-IGF-IR antibodies, including chimeric, b... | 01/05/2012 |
| 20110311443 | PHARMACEUTICAL COMPOSITION AND METHOD FOR IDENTIFYING A CANCEROUS AND/OR AN INFLAMMATORY DISEASE IN A PATIENT The invention relates to a method for treating a cancerous and/or an inflammatory disease in a patient, comprising internally administering to the patient an effective amount of a pharmaceutical preparation blocking the biological activity of at least one protein cluste... | 12/22/2011 |
| 20110311546 | Angiopoietin-2 specific binding agents Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies.... | 12/22/2011 |
| 20110300138 | HUMAN ANTI TSHR ANTIBODIES According to one aspect there is provided an isolated human antibody molecule which binds to the TSHR and which reduces ligand-induced stimulation of the TSHR but has no effect on TSHR constitutive activity, wherein the isolated human antibody molecule has the character... | 12/08/2011 |
| 20110300077 | Human Anti-Alpha-Synuclein Antibodies Provided are human alpha-synuclein-specific autoantibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for α-synuclein are also disclosed. The antibody, immun... | 12/08/2011 |
| 20110287005 | MONOCLONAL ANTIBODIES AGAINST AMYLOID BETA PROTEIN AND USES THEREOF The subject invention relates to monoclonal antibodies (e.g., 8F5 and 8C5) that may be used, for example, in the prevention, treatment and diagnosis of Alzheimer's Disease or other neurodegenerative disorders.... | 11/24/2011 |
| 20110280883 | FULLY HUMAN ANTI-EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODIES Disclosed are fully human anti-epidermal growth factor receptor (EGFR) antibodies, fragments thereof, and nucleic acid sequences encoding for the same. Further disclosed are methods of making and using the antibodies.... | 11/17/2011 |
| 20110280884 | ANTI-CD98 ANTIBODY A human antibody or a functional fragment thereof having specific binding ability to CD98 which is derived from the cell membrane of cancer cells and is in the form of a complex with a protein having an amino acid transporter activity (for example, LAT1) is disclosed. T... | 11/17/2011 |
| 20110274685 | ANTIBODIES THAT BIND HUMAN CD27 AND USES THEREOF Isolated monoclonal antibodies which bind to human CD27 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic and diagnostic methods for using the antibodies.... | 11/10/2011 |
| 20110274696 | ANTIBODIES TO CCR2 Provided are antibodies including human antibodies and antigen-binding portions thereof that specifically bind to CCR2, specifically human CCR2, and that may function to inhibit CCR2. Anti-CCR2 antibodies include those which bind to the first and/or second extracellular... | 11/10/2011 |
| 20110268727 | ANTI-INTERFERON-ALPHA ANTIBODIES The present invention relates generally to the generation and characterization of neutralizing anti-IFN-α monoclonal antibodies with broad reactivity against various IFN-α subtypes. The invention further relates to the use of such anti-IFN-α antibodies in the diagnos... | 11/03/2011 |
| 20110268739 | Human binding molecules having killing activity against enterococci and uses thereof Described are human binding molecules specifically binding to enterococci and having killing activity against enterococci, nucleic acid molecules encoding the human binding molecules, compositions comprising the human binding molecules and methods of identifying or prod... | 11/03/2011 |
| 20110268740 | FULLY HUMAN INFLUENZA M2 SPECIFIC ANTIBODIES The present invention relates to human antibodies, preferably to fully human antibodies, which are specifically binding to influenza M2e antigen. The invention further relates to individual light- and/or heavy chains of such antibodies, to nucleic acids encoding said an... | 11/03/2011 |
| 20110262448 | HUMAN ANTIBODIES THAT BIND MESOTHELIN, AND USES THEREOF The present disclosure provides isolated monoclonal antibodies that specifically bind to mesothelin with high affinity, particularly human monoclonal antibodies. Preferably, the antibodies bind human mesothelin. In certain embodiments, the antibodies are capable of inte... | 10/27/2011 |
| 20110250165 | Antibodies against CXCR4 and Methods of Use Thereof The invention provides human monoclonal antibodies, scFv antibodies, scFv-Fc fusions, a dAb (domain antibodies), Fab, Fab′ and F(ab)′2 fragments, single chain antibodies and/or minibodies that specifically bind to CXCR4. Also provide... | 10/13/2011 |
| 20110243840 | MONOCLONAL ANTIBODIES AGAINST ORTHOPOXVIRUSES The present invention relates to monoclonal antibodies that bind or neutralize Orthopoxviruses. The invention provides such antibodies, fragments of such antibodies retaining B5 or A33 binding ability, fully human antibodies retaining B5 or A33 binding ability, and phar... | 10/06/2011 |
| 20110230647 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY The present invention provides a novel lymphocyte inhibitory receptor termed BTLA which is expressed on both T and B cells, and identifies HVEM as interacting with BTLA. Methods and compositions for modulating BTLA-mediated signaling and interfering with the interaction... | 09/22/2011 |
| 20110223615 | Rapid Expression Cloning of Human Monoclonal Antibodies from Memory B Cells The present application provides methods for producing human monoclonal antibodies without using hybridoma technology, antibodies produced used the described methods, and methods for using the antibodies to treat or prevent disease conditions (e.g., infection by pathoge... | 09/15/2011 |
| 20110223176 | BASIGIN BINDING PROTEINS Isolated binding proteins, e.g., antibodies, which bind to Basigin (BSG), e.g., human BSG2, and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnost... | 09/15/2011 |
| 20110206663 | Anti-Interferon-Alpha Antibodies The present invention relates generally to the generation and characterization of neutralizing anti-IFN-α monoclonal antibodies with broad reactivity against various IFN-α subtypes. The invention further relates to the use of such anti-IFN-α antibodies in the diagnos... | 08/25/2011 |
| 20110200608 | FULLY HUMAN ANTIBODIES TO HIGH MOLECULAR WEIGHT-MELANOMA ASSOCIATED ANTIGEN AND USES THEREOF Disclosed herein are isolated human monoclonal antibodies, and functional fragments thereof, that specifically bind HMW-MAA. Nucleic acids encoding these antibodies, expression vectors including these nucleic acid molecules, and isolated host cells that express the nucl... | 08/18/2011 |
| 20110191866 | METHODS OF MAKING MONOCLONAL ANTIBODIES USING FUSION-PEPTIDE EPITOPE ADOPTIVE TRANSFER (F-PEAT) TECHNOLOGY Disclosed are compositions and methods for related to monoclonal antibodies specific for single amino acid variation in an antigen.... | 08/04/2011 |
| 20110189196 | METAL-CITRATE TRANSPORTER ANTIGEN FROM STREPTOMYCES COELICOLOR AND USES THEREOF The present invention relates to an isolated antigen from Streptomyces coelicolor that is useful for developing, inter alia, vaccines against pathogenic bacteria of humans and animals. The present invention also relates to vaccines and antibodies developed using ... | 08/04/2011 |
