Actor Marlon Brando has four patents, all named "Drumhead tensioning device and method."
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| Application No. | Application Title | Issue Date |
| 20120130049 | ALBUMIN-AMYLOID PEPTIDE CONJUGATES AND USES THEREOF The invention provides conjugates comprising albumin and a peptide derived from the C-terminal region of amyloid beta peptide, as well as uses thereof for the treatment of diseases characterized by the deposition of amyloid proteins and, in particular, for the treatment... | 05/24/2012 |
| 20120107829 | STABILIZING COMPOSITIONS FOR IMMOBILIZED BIOMOLECULES The present invention relates to the use of a composition comprising (a) at least three different amino acids, (b) at least two different amino acids and a saponin or (c) at least one dipeptide or tripeptide for stabilizing biomolecules immobilized on a solid carrier. T... | 05/03/2012 |
| 20120082715 | Stabilized products, processes and devices for preparing the same A composition comprising a glassified, stabilized particle preparation having a low water activity (between about 0.1 and 0.9) is provided. The preparations provide improved products with enhanced storage stability, less expensive cost of processing, and extended shelf ... | 04/05/2012 |
| 20120070378 | LANTHANIDE ION COMPLEXES AND IMAGING METHOD A Ianthanide complex, method of forming and method of using the lanthanide complex as a near-infrared luminescent material are described. The complex includes at least one lanthanide ion and at least one polydentate ligand derived from a molecule having the general form... | 03/22/2012 |
| 20120046447 | METHOD FOR PRODUCING CONJUGATE OF THYROXINE AND ALBUMIN It is an object of the present invention to provide a method for producing a conjugate of thyroxine and albumin with higher purity. The present invention provides a method for producing a conjugate of thyroxine and albumin which comprises: step (a) of converting a carbo... | 02/23/2012 |
| 20120041178 | Coenzyme Q10 Nanoparticles, Preparation Method Thereof and Composition Containing Said Nanoparticles Provided are a coenzyme Q10 nanoparticle, a method of preparing the same and a composition having the nanoparticle. According to the present invention, Coenzyme Q10 may be dissolved in only a water-miscible organic solvent, and easily made into a nano-sized particle and... | 02/16/2012 |
| 20120020893 | Intravascular Imaging Device and Uses Thereof The invention is directed to a probe-type imaging device useful to visualize interior surfaces, e.g., the lumen of blood vessels. Specifically, the probe-type device is particularly useful for direct tissue imaging in the presence or absence of molecular imaging agents.... | 01/26/2012 |
| 20120021050 | NANOPARTICLE FORMULATED GLYCOLIPID ANTIGENS FOR IMMUNOTHERAPY A composition for stimulating NKT cells to produce anti-cancer and anti-viral cytokines without causing anergy of NKT cells includes a glycolipid antigen and a nanoparticle conjugated with the glycolipid antigen. The glycolipid antigen and the nanoparticle are not antig... | 01/26/2012 |
| 20120021985 | ALBUMIN FUSION PROTEINS The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids ... | 01/26/2012 |
| 20120009205 | Modified Fc Molecules Disclosed is a process for preparing a pharmacologically active compound, in which at least one internal conjugation site of an Fc domain sequence is selected that is amenable to conjugation of an additional functional moiety by a defined conjugation chemistry through t... | 01/12/2012 |
| 20120003260 | Solid-Phase and Solution-Phase Synthesis of Glycosylphosphatidylinositol Glycans One aspect of the present invention relates to solution-phase approaches to GPI synthesis. Another aspect of the present invention relates to key building blocks, and syntheses thereof, useful for GPI assembly. Yet another aspect of the invention relates to an automated... | 01/05/2012 |
| 20120003222 | FZD8 EXTRACELLULAR DOMAINS AND FZD8 EXTRACELLULAR DOMAIN FUSION MOLECULES AND TREATMENTS USING SAME Methods of treatment using Fzd8 extracellular domains (ECDs), Fzd8 ECD fusion molecules, and/or antibodies that bind Fzd8 are provided. Such methods include, but are not limited to, methods of treating obesity and obesity-related conditions. Fzd8 ECDs and Fzd8 ECD fusio... | 01/05/2012 |
| 20110313681 | BIOMARKERS FOR PERIPHERAL ARTERY DISEASE This invention provides biomarkers whose concentrations in blood plasma are associated with the presence or absence of PAD in the patient from whom the plasma sample is taken. The invention also provides biomarkers for distinguishing between PAD patients who are long cl... | 12/22/2011 |
| 20110306551 | Modification of Factor VIII A Factor VIII derivative of formula (I): wherein: B represents C2 to C10 alkylene; m represents 0 or an integer from 1 to 19, n represents an integer from 1 to 20, and the sum of m and n is from 1 to 20; P represents a mono or polyradical of Factor... | 12/15/2011 |
| 20110301079 | NEUROMEDIN U RECEPTOR AGONISTS AND USES THEREOF Neuromedin U receptor agonists for use in the treatment of metabolic disorders such as obesity and diabetes are disclosed. In particular, disclosed are neuromedin U receptor agonists that comprise neuromedin S (NMS).... | 12/08/2011 |
| 20110280870 | HEPATOCYTE GROWTH FACTOR RECEPTOR ANTAGONISTS AND USES THEREOF Hepatocyte growth factor (HGF) receptor antagonists are provided. The HGF receptor antagonists include HGF receptor antibodies and fragments thereof. The HGF receptor antagonists can be employed to block binding of HGF to HGF receptors or substantially inhibit HGF recep... | 11/17/2011 |
| 20110263502 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES The present invention provides methods and compositions that permit controlled and prolonged drug release in vivo. The compounds are either prodrugs with tunable rates of release, or conjugates of the drug with macromolecules which exhibit tunable controlled rates of re... | 10/27/2011 |
| 20110262347 | METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF COMPOUNDS Disclosed are compositions and methods related to multivalent compositions targeted to cells and tissues. The disclosed targeting is useful for treatment of cancer and other diseases and disorders.... | 10/27/2011 |
| 20110236884 | MICROBUBBLES FOR AFFINITY SEPARATION The present invention relates to methods, compositions and kits for affinity isolation, affinity purification and affinity assay based on microbubbles coated with an affinity molecule. Particularly, the invention provides protein microbubbles coated with an affinity mol... | 09/29/2011 |
| 20110230411 | Albumin fibers and fabrics and methods of generating and using same Provided are method of generating a fiber from a globular protein such as albumin. Also provided are albumin fibers and fabrics and methods of using same for bonding a damaged tissue or for ex vivo or in vivo formation of a tissue.... | 09/22/2011 |
| 20110230644 | MICROBUBBLES FOR AFFINITY SEPARATION The present invention relates to methods, compositions and kits for affinity isolation, affinity purification and affinity assay based on microbubbles coated with an affinity molecule. Particularly, the invention provides protein microbubbles coated with an affinity mol... | 09/22/2011 |
| 20110189751 | METHODS AND COMPOSITIONS COMPRISING HEAT SHOCK PROTEINS Compositions, and uses thereof, which are beneficial for eukaryotic cells in culture, and methods for their use in promoting cell growth, viability and recombinant protein expression. The methods disclosed in the present application are useful, for example, for improvin... | 08/04/2011 |
| 20110183907 | FACTOR VIII, VON WILLEBRAND FACTOR OR COMPLEXES THEREOF WITH PROLONGED IN VIVO HALF-LIFE The present invention relates to modified nucleic acid sequences coding for coagulation factor VIII (FVIII) and for von Willebrand factor (VWF) as well as complexes thereof and their derivatives, recombinant expression vectors containing such nucleic acid sequences, hos... | 07/28/2011 |
| 20110166072 | Polypeptides Selective for avB3 Integrin, Including Pegylated Polypeptides, And Pharmaceutical Uses Thereof The invention provides disintegrin variants, and more specifically to disintegrin variants which are selective αvβ3 integrin antagonists for treatment and prevention of αvβ3 integrin-associated diseases. The present invention also relates to pegylated proteins, incl... | 07/07/2011 |
| 20110142762 | Conjugates for medical imaging comprising carrier, targeting moiety and a contrast agent This invention relates to the delivery of agents to the body. One particular class of such agents are contrast agents useful in medical imaging techniques. The agents may be metals useful as contrast agents in magnetic resonance imaging (MRI), or in nuclear imaging, inc... | 06/16/2011 |
| 20110135736 | Compositions and Methods for Producing Vascular Occlusion using a Solid-phase Platelet Binding Agent The present invention relates generally to methods and compositions for targeting and delivering solid-phase platelet-dependent vascular occlusion agents. In particular, particles or coils or stents coated with platelet binding agents are directed to target vasculature,... | 06/09/2011 |
| 20110130329 | Glp-1 Fusion Peptides, Their Production and Use The present invention provides fusion peptides having GLP-1 activity and enhanced stability in vivo, in particular resistancy to dipeptidyl peptidase IV. The fusion peptide comprises as component (I) N-terminally a GLP-1(7-35, 7-36 or 7-37) sequence and as component (II... | 06/02/2011 |
| 20110117139 | FULLY SYNTHETIC ALBUMIN ANALOG The present invention relates to a fully synthetic albumin analog, to a hemocompatible coating for medical devices containing the fully synthetic albumin analog, as well as to medical devices coated with the hemocompatible coating. The albumin analog preferably has two ... | 05/19/2011 |
| 20110117082 | Soluble Tumor Necrosis Factor Receptor Mutant A soluble tumor necrosis factor receptor 2 (TNFRII) mutant has an amino acid substitution at position 92Glu compared with the wild TNFRII. The mutant improves the cytotoxicity capacity of neutralizing TNFalpha and lymphotoxin. The mutant and fusion protein comprising it... | 05/19/2011 |
| 20110092413 | Albumin-Fused Kunitz Domain Peptides The invention relates to proteins comprising serine protease inhibiting peptides, such as Kunitz domain peptides (including, but not limited to, fragments and variants thereof) fused to albumin, or fragments or variants thereof. These fusion proteins are herein collecti... | 04/21/2011 |
| 20110086768 | TRANSFERRIN FUSION PROTEIN LIBRARIES Fusion proteins comprising a transferrin moiety and integrin binding domain and peptide libraries thereof are disclosed. The present invention includes a method of screening transferrin and integrin peptide libraries displayed in fusion proteins expressed by host cells.... | 04/14/2011 |
| 20110082282 | PROCESS OF PREPARING CONJUGATES OF ALLIUM ORGANOSULFUR COMPOUNDS WITH AMINO ACIDS, PEPTIDES, AND PROTEINS Processes using Allium tissue homogenates and extracts in a simple and cost-effective manner to maximize the yields and recovery of thiosulfinates from Allium tissues and related organisms possessing alliinase, LF synthase and/or S-alk(en)yl-L-cysteine sul... | 04/07/2011 |
| 20110059889 | PEPTIDES THAT BLOCK THE BINDING OF IgG TO FcRn The invention relates to peptides which bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used for example, in treating autoimmune diseases and inflammatory d... | 03/10/2011 |
| 20110046054 | ANTI DIABETIC PROTEIN The present invention relates to a novel hypoglycemic/anti-hyperglycemic protein named ADMc1 purified from the seeds of Momordica charantia for control of hyperglycemia. The process for the purification of novel hypoglycemic/anti-hyperglycemic protein named ADMc1... | 02/24/2011 |
| 20110020649 | METHOD FOR IMMOBILIZATION, PHYSIOLOGICALLY ACTIVE SUBSTANCE-IMMOBILIZED CARRIER, CARRIER FOR IMMOBILIZATION, CARRIER, AND PROCESS FOR PRODUCING CARRIER An immobilization method for immobilizing a physiologically active substance on a solid phase carrier, the method including: bringing the solid phase carrier into contact with an acid anhydride functional group-containing silane coupling agent represented by the followi... | 01/27/2011 |
| 20110008900 | DEPLETION OF PLASMA PROTEINS This invention relates to methods of analysis, and in particular to methods for the preliminary fractionation of samples in which low abundance molecules of interest, for example proteins, polysaccharides or fatty acids, are present together with more abundant molecules... | 01/13/2011 |
| 20110002888 | Albumin Fusion Proteins The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids ... | 01/06/2011 |
| 20100331525 | ANTITUMORAL AGENTS WITH A BENZOPHENANTHRIDINE STRUCTURE AND FORMULATIONS CONTAINING THEM The use of benzophenanthridine alkaloids and the salts thereof for the preparation of medicaments for the treatment of tumors is disclosed.... | 12/30/2010 |
| 20100330701 | USE OF HEAT-RESISTANT BIOTIN-BINDING PROTEIN, AND SOLID SUPPORT HAVING THE PROTEIN ATTACHED THERETO The present invention relates to a solid support having a heat-resistant biotin-binding protein attached thereto. The present invention also relates to the use of the solid support of the present invention having a heat-resistant biotin-binding protein attached thereto.... | 12/30/2010 |
| 20100323421 | METHOD FOR CHEMICALLY MODIFYING BIOPOLYMER AND POLYPEPTIDE It is an object of the present invention to provide a method for chemically modifying biopolymer and polypeptide with a hydrophobic compound or a compound which causes degradation or reaction under basic condition. The present invention provides a method for producing a... | 12/23/2010 |