Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Application No. | Application Title | Issue Date |
| 20120129776 | Bioactive peptides and method of using same Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.... | 05/24/2012 |
| 20120129264 | Method for Transforming a Bacterium Belonging to the Streptococcus Genus by Natural Competence The present invention relates to peptides, nucleic acids and methods for transforming a bacterium belonging to the Streptococcus genus by natural competence and their use in the food and feed industry.... | 05/24/2012 |
| 20120107321 | Antibodies And Epitopes Specific To Misfolded Prion Protein The present invention relates to antibodies and immunogenic peptides specific to misfolded prion protein (PrP, e g, PrPSc), and uses thereof. The immunogenic peptides comprise the amino acid sequence tyrosine-methionine-leucine (YML). The antibodies or peptid... | 05/03/2012 |
| 20120108502 | NOVEL ANTI-PARASITIC COMPOUNDS A novel structural class of highly N-methylated linear lipopeptide compounds useful for the treatment of parasitic disease.... | 05/03/2012 |
| 20120108494 | INHIBITORS OF INTRACELLULAR UROKINASE PLASMINOGEN ACTIVATOR AND METHODS OF USE THEREOF The present invention provides compositions comprising amiloride amino acid and peptide conjugates. Efficient methods are also provided for administering the compositions for treating cancer and for delivering an amiloride conjugate into cancer cells in a subject in nee... | 05/03/2012 |
| 20120107869 | ORGANIC COMPOUNDS Disclosed is a method for the production of a heterologous polypeptide of interest with a homogenous N-terminus, using a fusion polypeptide comprising the polypeptide of interest and N-terminally thereto a polypeptide exhibiting autoproteolytic function, said method com... | 05/03/2012 |
| 20120107319 | Pharmaceutical compositions comprising antibodies binding to the intracellular domain of EBV (Epstein-Barr virus) latent membrane protein-1 (LMP1) The invention relates to pharmaceutical and vaccine compositions comprising an antibody binding specifically to the intracellular domain of EBV protein LMP1.... | 05/03/2012 |
| 20120107243 | PEPTIDE-MEDIATED NON-COVALENT DELIVERY OF ACTIVE AGENTS ACROSS THE BLOOD-BRAIN BARRIER The peptides described herein can function as carrier peptides. These peptides can associate with (e.g., non-covalently bind) biologically active molecules or imaging agents to transport the biologically active molecules or imaging across the blood-brain barrier. In som... | 05/03/2012 |
| 20120083427 | KINASE AND PHOSPHATASE ASSAYS Compositions, methods, and kits for detecting and monitoring kinase, phosphatase and protein post-translational modification activity are described. The compositions typically include a peptide, a detectable moiety, and a protease cleavage site. Modification of a peptid... | 04/05/2012 |
| 20120070875 | Amino Acid Sequences which Enhance Peptide Conjugate Solubility The present invention provides peptide conjugates having improved solubility as well as increased secretion during cell based production, as well as methods of utilizing such peptides. The peptide conjugates include a short peptide domain defined by the amino acid seque... | 03/22/2012 |
| 20120052034 | HAIR TREATMENT COMPOSITION WITH NATURALLY - DERIVED PEPTIDE IDENTICAL TO HUMAN HAIR A hair treatment composition containing at least one peptide identical to human hair, where preferably the peptide is synthesized from naturally-derived amino acids and can serve as a natural alternative to the commonly used human or animal derived (wool) keratin peptid... | 03/01/2012 |
| 20120052574 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS Compositions and methods for improved delivery of macromolecules into eukaryotic cells are provided. Fusogenic peptides from fusion proteins of non-enveloped viruses enhance the efficiency of transfection of eukaryotic cells mediated by transfection agents such as catio... | 03/01/2012 |
| 20120046443 | Novel biomimetic peptoid polymers The present invention provides for novel peptoid oligomers that are capable of self-assembling into two-dimensional sheet structures. The peptoid oligomers can have alternately hydrophilic or polar side-chains and hydrophobic or apolar side-chains. The peptoid oligomers... | 02/23/2012 |
| 20120045394 | HUMAN AND MOUSE TARGETING PEPTIDES IDENTIFIED BY PHAGE DISPLAY The present invention concerns methods and compositions for in vivo and in vitro targeting. A large number of targeting peptides directed towards human organs, tissues or cell types are disclosed. The peptides are of use for targeted delivery of therapeutic agents, incl... | 02/23/2012 |
| 20120045474 | Substrate peptide sequences for plague plasminogen activator and uses thereof The present invention is directed to peptide sequences that were identified from combinatorial libraries and could serve as substrates of plague plasminogen activator (Pla). Another aspect of the present invention is drawn to peptides derived from the substrates for Pla... | 02/23/2012 |
| 20120040912 | PROTEASOME-ACTIVATING ANTI-AGING PEPTIDES AND COMPOSITIONS CONTAINING SAME The present invention relates to peptidic compounds of general formula (I):
| 02/16/2012 |
| 20120040918 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID The present invention provides a novel class of peptide nucleic acid derivatives, which show good cell penetration and strong binding affinity for nucleic acid.... | 02/16/2012 |
| 20120039894 | IDENTIFICATION OF THERAPEUTIC AGENTS FOR HIV INFECTION A cell surface molecule designated DCIR (for dendritic cells ImmunoReceptor), a member of a recently described family of DC-expressing C-type lectin receptors, has been shown to participate to the capture of human immunodeficiency virus (HIV) and promote infection in tr... | 02/16/2012 |
| 20120039989 | ERYTHROCYTE-BINDING THERAPEUTICS Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fu... | 02/16/2012 |
| 20120035094 | F11 RECEPTOR (F11R) ANTAGONISTS AS THERAPEUTIC AGENTS The present invention provides a compound including a peptidomimetic which interacts sterically with the binding site of a F11R molecule, the peptidomimetic including a peptidomimetic having the SEQ ID NO: 4D. The present invention also provides a method for treating a ... | 02/09/2012 |
| 20120034317 | Prediction of Response to Platinum-Based Therapy Method for determining whether a mammalian subject having a cancer belongs to a first or a second group, wherein subjects of the first group are more likely to respond to a platinum-based therapy than subjects of the second group, comprising the steps of: evaluating the... | 02/09/2012 |
| 20120035108 | SPRAY BASE MATERIAL INCLUDING LOW-MOLECULAR GELATOR There is provided a spray base material that can be safely used with a sense of security, that prevents leakage of liquid from a spray container, that is sprayable under any condition (when inverted, for example), that is sprayable to achieve uniform coating of the surf... | 02/09/2012 |
| 20120034163 | NON-INVASIVE TOOLS FOR DETECTING VULNERABLE ATHEROSCLEROTIC PLAQUES The present invention relates to a polypeptide comprising the sequence RILAR (SEQ ID NO: 3), the use thereof in imaging methods, in diagnostic or prognostic methods and for use as a medicament.... | 02/09/2012 |
| 20120034252 | COMPOSITIONS AND METHODS FOR INDUCING AN IMMUNE RESPONSE The present invention provides compositions and methods for inducing an immune response in a subject. In particular, the present invention provides compositions comprising immunostimulatory ligands (ISL) and methods of inducing an immune response in a subject therewith.... | 02/09/2012 |
| 20120027703 | NOVEL PROTEASOME-ACTIVATING ANTI-AGING PEPTIDES AND COMPOSITIONS CONTAINING SAME The present invention relates to peptidic compounds of general formula (I):
In addition, the present i... | 02/02/2012 |
| 20120027720 | PEPTIDE CONJUGATES The present invention provides novel peptide conjugates. Peptide conjugates of the invention can be used as therapeutic agents. Peptide conjugates invention may also be used to deliver one or more additional active agents. The present invention also provides methods for... | 02/02/2012 |
| 20120027778 | Frizzled-Binding Agents and Uses Thereof Novel anti-cancer agents, including, but not limited to, antibodies and other polypeptides, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. M... | 02/02/2012 |
| 20120028888 | APJ RECEPTOR COMPOUNDS The invention relates generally to compounds which are allosteric modulators (e.g., negative and positive allosteric modulators, allosteric agonists, and ago-allosteric modulators) of the G protein coupled receptor apelin, also known as the APJ receptor. The APJ recepto... | 02/02/2012 |
| 20120028880 | VEGFR-1/NRP-1 TARGETING PEPTIDES The present invention concerns the fields of molecular medicine and targeted delivery of therapeutic agents. More specifically, the present invention relates to the identification of novel peptide sequences that incorporate the amino acids Leu-Pro-Arg (LPR), and particu... | 02/02/2012 |
| 20120027677 | Prion-specific peptoid reagents The invention relates to peptoid reagents that interact preferentially with a pathogenic form of a conformational disease protein as compared to a nonpathogenic form of the conformational disease protein where the peptoid reagent comprises an amino-terminal region, a ca... | 02/02/2012 |
| 20120028350 | BONE MARROW TARGETING PEPTIDES A peptide for targeting bone marrow consists of about 5 to about 25 amino acids and includes an amino acid sequence that targets the peptide to bone marrow.... | 02/02/2012 |
| 20120020881 | Triaryl-sulphonium compounds, kit and methods for labeling positron emitting isotopes This invention relates to novel compounds suitable for labeling by positron emitting isotopes, such as 18F, 11C, 13N and 15O, through appropriate labeling reagents, such as 18F reagents and methods of preparing such... | 01/26/2012 |
| 20120020964 | Antibodies for Norovirus Norovirus antigen peptides are described having an amino acid sequence selected from the group consisting of SEQ ID NOS: 1-16, or fragments thereof. Such peptides can be used in the preparation of antiviral therapies such as vaccines, methods of preparing antibodies to ... | 01/26/2012 |
| 20120021454 | RAPID FRET-BASED DIAGNOSIS OF BACTERIAL PATHOGENS The invention comprises a substrate for detection of micro-organisms, wherein said substrate comprises a set of molecular markers linked, optionally with linker molecules or moeieties, to a di-, or tripeptide consisting of amino acids X1 and X2, or X1, X2 and X3, in whi... | 01/26/2012 |
| 20120021430 | FUNCTIONAL LIPID CONSTRUCTS The invention relates to methods for effecting qualitative and quantitative changes in the functional moieties expressed at the surface of cells and multi-cellular structures, and functional lipid constructs for use in such methods. In particular, the invention relates ... | 01/26/2012 |
| 20120021990 | PEPTIDES USEFUL AS DUAL CASPASE-2/-6 INHIBITORS AND THEIR BIOLOGICAL APPLICATIONS The present disclosure relates to peptides having a core sequence as described herein as well as application of the disclosed technology as inhibitors of caspase-2 and/or -6 activity.... | 01/26/2012 |
| 20120022371 | Compositions and methods for detecting and treating tumors containing acidic areas Improved compounds have been developed which are structured to be sequestered with very high specificity in acidic areas of tissues. When the compounds contain a radioisotope effective to report the presence of the compound the compounds are for detecting tumors contain... | 01/26/2012 |
| 20120020904 | NOVEL PROTEASOME-ACTIVATING LIGHTENING PEPTIDES AND COMPOSITIONS CONTAINING SAME The present invention relates to depigmenting, lightening and/or whitening peptidic compounds of general formula (I)
| 01/26/2012 |
| 20120014925 | Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof The invention relates to a novel class of self-assembling peptides, compositions thereof, methods for the preparation thereof and methods of use thereof. The invention also encompasses methods for tissue regeneration, increasing the production of extracellular matrix pr... | 01/19/2012 |
| 20120014874 | PHOTOSENSITIZER-METAL NANOPARTICLE CHARGE COMPLEX AND COMPOSITION CONTAINING THE COMPLEX FOR PHOTODYNAMIC THERAPY OR DIAGNOSIS Provided are a photosensitizer-metal nanoparticle charge complex and a composition for photodynamic therapy or diagnosis containing the same. The complex includes a metal nanoparticle, a photosensitizer charged with a first charge, and a linker bound to the metal nanopa... | 01/19/2012 |
