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| Application No. | Application Title | Issue Date |
| 20120128779 | PROCESS FOR PRODUCING PROTEIN MICROPARTICLES The present invention relates to a process for producing protein microparticles in dilute organic acid solutions and in the absence of an alcohol such as ethanol. The microparticles are formed by dissolving a cereal prolamin protein in a concentrated organic acid soluti... | 05/24/2012 |
| 20120128760 | LIPID COMPOSITIONS Disclosed herein are lipid compositions comprising a cationic lipid of formula (I), a neutral lipid, a sterol and a PEG or PEG-modified lipid, wherein formula (I) is (F). Also disclosed are methods of producing the cationic lipid of formula (I).... | 05/24/2012 |
| 20120082632 | Topical drug delivery system with dual carriers A drug delivery system, formed as a tissue penetrating solution, comprising:
| 04/05/2012 |
| 20120082709 | COMPOSITIONS AND METHODS FOR DELIVERY OF MATERIALS Compositions for delivering release materials, for example drugs, agricultural materials, other bioactive materials, cosmetic materials, organic or inorganic compounds which take part in or catalyse a chemical reaction, a fragrance-emitting material for a vaporizer, or ... | 04/05/2012 |
| 20120046369 | Methods for enhancing the stability of foods, beverages, and cosmetics using natural products derived from non-allergenic proteinaceous sources The present invention relates to compositions with effective metal chelating activity and utility as natural antioxidants in food, beverages, nutritional supplements and cosmetics. The compositions of the present invention may be prepared by enzymatically hydrolyzing hy... | 02/23/2012 |
| 20120046349 | COMPOSITIONS FOR TARGETING CONDUCTING AIRWAY CELLS COMPRISING ADENO-ASSOCIATED VIRUS CONSTRUCTS An artificial AAV capsid comprising a heterologous conducting airway targeting sequence is provided. The artificial AAV is useful as a targeting moiety, for delivery of heterologous molecules which are associated therewith. The artificial AAV is also useful in the gener... | 02/23/2012 |
| 20120039980 | COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE Methods of preventing adhesion between issues are provided that utilizes in situ crosslinked biomaterials. The biomaterial contains at least the crosslinked product of two biocompatible, non-immunogenic components having reactive groups thereon, with the functional grou... | 02/16/2012 |
| 20120039956 | DRY STORAGE STABILIZING COMPOSITION FOR BIOLOGICAL MATERIALS The present invention includes compositions and drying methods for preserving sensitive bioactive materials, such as peptides, proteins, hormones, nucleic acids, antibodies, drugs vaccines, yeast, bacteria (probiotic or otherwise), viruses and/or cell suspensions, in st... | 02/16/2012 |
| 20120039813 | INTRINSICALLY COLORED, LUMINESCENT SILK FIBROIN AND A METHOD OF PRODUCING THE SAME This present invention proposes a method of producing intrinsically colored, luminescent silk fibroin by feeding silkworms with feed comprising the luminescent dyes as well as the appropriate degumming process to remove sericin while retaining the dyes in silk fibroin a... | 02/16/2012 |
| 20120027694 | INDUCIBLE RELEASE VEHICLES This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications fo... | 02/02/2012 |
| 20120021020 | BRANCHED AMPHIPATHIC OLIGO-PEPTIDES THAT SELF-ASSEMBLE INTO VESICLES The present invention provides branched amphipathic peptides and vesicles formed thereof. The peptides comprise a polar/positively charged C-terminal segment, a branch point, and two hydrophobic N -terminal segments extending from the branch point. The vesicles are form... | 01/26/2012 |
| 20110319341 | METHOD OF CONTROLLING PESTS WITH BIOSURFACTANT PENETRANTS AS CARRIERS FOR ACTIVE AGENTS A penetrating composition can include an active agent that has an activity that is either beneficial for plants or controls pests. The composition can also include a penetrant that is present in an effective amount for carrying the at least one active agent into or thro... | 12/29/2011 |
| 20110319499 | Methods for the Detection of Advanced Glycation Endproducts and Markers for Disease The present invention provides compositions and methods for detecting carboxymethyl-lysine (CML) and circulating receptor for advanced glycation end (RAGE) products, and methods for correlating CML and RAGE levels with age-related disease, hi particular, serum CML and/o... | 12/29/2011 |
| 20110312497 | USE OF HYDROPHOBIN AS A SPREADING AGENT The present invention relates to the use of hydrophobin as a spreading agent, in particular in cosmetic or pharmaceutical compositions. The invention further relates to compositions for treating surfaces, in particular cosmetic or pharmaceutical compositions for topical... | 12/22/2011 |
| 20110311629 | NON-ADHESIVE ELASTIC GELATIN MATRICES The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s... | 12/22/2011 |
| 20110305768 | QUICK-DISSOLVING ORAL THIN FILM FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS This invention describes a quick-dissolving thin film strips comprising bioactive components encapsulated within pH-sensitive polymeric microparticles. The microparticles are embedded within the thin film and provide protection to components encapsulated within. The inv... | 12/15/2011 |
| 20110300127 | DRUG-CONTAINING COMPOSITION It is an object of the present invention to provide a drug-containing composition capable of stably retaining a water-soluble compound without the loss of drug efficacy of a pharmaceutically active ingredient and thus preventing the compound from diffusing in the body, ... | 12/08/2011 |
| 20110300094 | Silicone Oil-In-Water Emulsions A silicone oil-in-water emulsion comprising 3 to 90% by volume of a silicone oil phase, characterized in that the emulsion is stabilized by a protein and/or peptide present at 0.25 to 20% by weight of the emulsion. The emulsion contains less than 25% by weight and prefe... | 12/08/2011 |
| 20110301131 | Drug Delivery Implants and Processes for Their Preparation The invention discloses an implant suitable for delivery of at least one drug, the implant comprising a fibrillar collagen matrix having, as measured in Example 1, a viscosity of greater than 100 mPas, optionally greater than 103 mPas, further optionally greater than 10... | 12/08/2011 |
| 20110288363 | Biologically Enhanced Irrigants Compositions, systems and methods utilizing engineered surgical irrigants providing delivery of components with therapeutic or other secondary benefits. Engineered irrigants provide targeted delivery of desired agents, including agents for propulsion of nano-devices, ag... | 11/24/2011 |
| 20110280944 | FIBROUS MICROCAPSULES AND METHODS OF ASSEMBLY AND USE THEREOF The present invention relates to assembly of peptide amphiphiles and biopolymers into fibrous microcapsules, and uses thereof. In particular, the present invention provides devices, compositions, and methods for interfacial self-assembly of peptide amphiphiles and biopo... | 11/17/2011 |
| 20110274641 | Non-Petrochemically Derived Cationic Emulsifiers That Are Neutralized Amino Acid Esters and Related Compositions and Methods The invention includes a method of increasing the substantivity of a personal care composition to hair, skin or nails by preparing a composition of an aqueous phase, a non-aqueous phase and a neutralized amino acid ester that is a reaction product of a neutral amino aci... | 11/10/2011 |
| 20110274761 | POLYMER CARRIER Compositions and methods for delivering bioactive agents, such as vitamins, hormones, nutrients and drugs, by stabilizing and or solubilizing these agents in a polymer matrix. The carrier polymers can be used in drug delivery and are useful for delivery of small molecul... | 11/10/2011 |
| 20110269849 | Emulsions and Methods for the Preparation Thereof, and Methods for Improving Oxidative Stability of Lipids An emulsion includes a lipid, an emulsifier, and ε-polylysine. A method for improving oxidative stability of a lipid includes forming an emulsion that includes the lipid, an emulsifier, and ε-polylysine, such that the emulsion further includes a complex layer at an oi... | 11/03/2011 |
| 20110262347 | METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF COMPOUNDS Disclosed are compositions and methods related to multivalent compositions targeted to cells and tissues. The disclosed targeting is useful for treatment of cancer and other diseases and disorders.... | 10/27/2011 |
| 20110256224 | METHODS AND COMPOSITIONS FOR TARGETED DELIVERY The disclosure provides compounds and compositions, and methods of using these compounds and compositions, for the targeted delivery of therapeutic agents. In one embodiment, these compositions are used for the tumor-targeted delivery of chemotherapeutic agents useful f... | 10/20/2011 |
| 20110250153 | OLIGOMERIC BIOSURFACTANTS IN DERMATOCOSMETIC COMPOSITIONS Oligomeric acylated biosurfactants (“OABs”) having low critical micelle concentrations of from about 1.0 ppm to about 200 ppm, preferably less than about 50 ppm, in an aqueous solution of Minimal Essential Media that can lower the surface tension in the aqueous MEM ... | 10/13/2011 |
| 20110244046 | Charge Reversible Polymers Described are charge reversible polymers, peptides and their resulting colloidal particles, comprising polymers and peptides having primary and secondary amines that are protected as easily hydrolysable amides. The amides are charge-reversible such that at neutral pH th... | 10/06/2011 |
| 20110236492 | DRY POWDER INHALER FORMULATIONS COMPRISING SURFACE-MODIFIED PARTICLES WITH ANTI-ADHERENT ADDITIVES The present invention is concerned with a refinement of the processing of particles that are to form a dry powder formulation which is to be administered to the lung using a dry powder inhaler (DPI) device. In particular, the present invention provides the processing of... | 09/29/2011 |
| 20110236497 | Compositions and Methods for Improved Retention of a Pharmaceutical Composition at a Local Administration Site Disclosed herein are compositions comprising cross-linkers for cross-linking a retention vehicle polymer. The compositions are particularly useful for local administration of a bioactive agent, wherein prolonged or extended availability of the bioactive agent at the sit... | 09/29/2011 |
| 20110230406 | AFFINITY PEPTIDES TOWARD BMP-2 We have disclosed affinity peptides toward BMP-2. More specifically we have disclosed an affinity biomatrix where the affinity peptide is covalently attached to a biocompatible, biodegradable polymer. The affinity biomatrix is useful in preparing controlled release devi... | 09/22/2011 |
| 20110229569 | COMPOSITIONS EXHIBITING DELAYED TRANSIT THROUGH THE GASTROINTESTINAL TRACT The present invention provides a composition exhibiting delayed transit through the gastrointestinal tract comprising one or more active agents, fenugreek fiber and at least one pharmaceutically acceptable excipient. The present invention further relates to gastroretent... | 09/22/2011 |
| 20110223153 | MODIFIED SILK FILMS CONTAINING GLYCEROL The present invention provides for compositions and methods for preparing aqueous insoluble, ductile, flexible silk fibroin films. The silk films comprise silk fibroin and about 10% to about 50% (w/w) glycerol, and are prepared by entirely aqueous processes. The ductile... | 09/15/2011 |
| 20110212028 | CHEMICALLY MODIFIED CELL-PENETRATING PEPTIDES FOR IMPROVED DELIVERY OF GENE MODULATING COMPOUNDS The present invention relates to a system for intracellular delivery of a cargo comprising at least one component A chosen from aliphatic linear or branched moieties with at least 4 carbon atoms and/or cyclic ring systems comprising 2-4 rings which may contain several h... | 09/01/2011 |
| 20110206606 | STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND METHODS FOR PREPARATION Stabilized radiopharmaceutical formulations are disclosed. Methods of making and using stabilized radiopharmaceutical formulations are also disclosed. The invention relates to stabilizers that improve the radiostability of radiotherapeutic and radiodiagnostic compounds,... | 08/25/2011 |
| 20110207764 | CYCLOPOLYSACCHARIDE COMPOSITIONS The present invention is directed to a composition including: (a) an active ingredient other than bendamustine; (b) a charged cyclopolysaccharide comprising at least one charged group; and (c) a stabilizing agent comprising at least one charged group having a charge opp... | 08/25/2011 |
| 20110183913 | NOVEL LIPID DIPEPTIDE AND GEL There is provided a gelator that is capable of forming a gel by an extremely small amount of addition in a wide pH range from acidic to alkaline regions, and a gel having high environmental compatibility, biocompatibility, and biodegradability. A gelator comprising: a l... | 07/28/2011 |
| 20110177997 | Cross-Beta Silk Genes The present invention relates to silk proteins which can be used to produce silk with a cross-beta structure, as well as nucleic acids encoding such proteins. The present invention also relates to recombinant cells and/or organisms which synthesize silk proteins. Silk p... | 07/21/2011 |
| 20110171239 | pH INDUCED SILK GELS AND USES THEREOF This invention provides for compositions, methods and devices for rapidly converting silk fibroin solution into a silk fibroin gel using direct application of voltage, in a process called electrogelation. The silk fibroin gel may be reversibly converted back to liquid f... | 07/14/2011 |
| 20110172315 | COMPOSITION FOR CRYOPRESERVATION OF CELLS AND TISSUES A composition for cryopreservation of cells and tissues of human and other animals in a safe manner without using toxic substances such as DMSO, as well as for freeze preserving or freeze-drying of foods and pharmaceuticals. In examples, ε-poly-L-lysine is reacted with... | 07/14/2011 |
