Class 514/719 - Alicyclic ring

Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the compound contains an alicyclic
No. of applications: 39
Last issue date: 05/24/2012

Application No.	Application Title	Issue Date
20120129925	SHIP 1 MODULATORS The present invention includes the use of pelorol, related compounds and pharmaceutical compositions thereof as modulators of SHIP 1 activity. This invention also provides novel terpene compounds capable of modulating SHIP 1 activity and methods of synthesis thereof....	05/24/2012
20120053180	CYCLOHEXANE ANALOGUES AS GPR119 AGONISTS This invention relates to a series of substituted cyclohexane containing analogues which are agonists of GPR119 intended to treat metabolic diseases mediated by GPR119 including Type I & II diabetes mellitus. Diabetes mellitus is an ever-increasing threat to human h...	03/01/2012
20120052142	BIOLOGICALLY ACTIVE COMPOSITIONS FROM Schisandra chinensis FOR TREATING COLORECTAL CANCER A biologically active composition to treat colorectal cancer includes an extract of the plant Schisandra chinensis and a suitable pharmaceutical formulation. The extract can be at least one of gomisin A, angeloylgomisin H, deoxyschisandrin and gomisin N, showing ...	03/01/2012
20110269842	COMPOSITIONS COMPRISING CB RECEPTOR AGONISTS, USES THEREOF AND METHODS FOR THEIR PREPARATION Provided are compositions including (3R, 4R, 6R)-stereoisomers of phenyl substituted pinenes having CB receptor agonist properties, methods of treating diseases or disorders with the pharmaceutical compositions, and processes for their preparation are also provided....	11/03/2011
20110263539	SHIP 1 MODULATOR COMPOUNDS The present invention provides the use of pelorol analogs of Formula, (I) and pharmaceutical compositions thereof as modulators of SHIP 1 activity. A compound or a pharmaceutical composition of the present invention may be used for the treatment or prophylaxis of an inf...	10/27/2011
20110213026	EXTRACTS WITH LIVER-X-RECEPTOR MODULATORS, COMPOUNDS AND THEIR USE ESPECIALLY IN WEIGHT CONTROL The invention relates to the use, or methods (especially with regard to animals, especially human, that are in need of such treatment) comprising the use, of an extract and/or one or more natural compounds from plants or parts of plants, respectively, from a genus selec...	09/01/2011
20110189294	PESTICIDAL COMPOSITIONS A formulated composition suitable for controlling or preventing pathogenic damage in a plant comprising (A) at least one solid active ingredient having a water solubility of at most 100 μg/litre at 25° C. at neutral pH, in an amount of at least 1 weight %, based on th...	08/04/2011
20110152373	HAIR GROWTH PROMOTING AGENT CONTAINING 15,15-DIFLUOROPROSTAGLANDIN F2ALPHA DERIVATIVE AS ACTIVE INGREDIENT The present invention provides a new pharmaceutical application of a 15,15-difluoroprostaglandin F_2α derivative. As a result of intensive studies in order to find a new pharmaceutical application of a 15,15-difluoroprostaglandin F_2α derivative, i...	06/23/2011
20110124741	RADIOSENSITIZER COMPOSITIONS COMPRISING SCHISANDRA CHINENSIS(TURCZ.)BAILL AND METHODS FOR USE The present invention provides a method of potentiating radiation therapy for treatment of a cancer or tumor comprising administrating to a subject in need thereof a therapeutically effective amount of a radiosensitizer in combination of a radiation therapy to a locus o...	05/26/2011
20110105507	VINYL ETHER COMPOUNDS AND METHODS OF THEIR PREPARATION AND USE Provided are new functionalized surfactants and methods of their preparation and use. The surfactants are compounds of formula I: wherein R¹, R², and R³are as defined herein....	05/05/2011
20110065744	Method Of Inhibiting Mucin Secretion A method of inhibiting mucus secretion in an individual that includes administering an effective amount of a composition which comprises guaifenesin....	03/17/2011
20100261772	Cycloalkylidene Compounds As Selective Estrogen Receptor Modulators The present invention relates to compounds of formula (I) with a variety of therapeutic uses, more particularly the substituted cyclic alkylidene compounds are useful for selective estrogen receptor modulation. ...	10/14/2010
20100240748	TETRAHYDRONAPHTHALEN-2-OL DERIVATIVES The present invention relates to novel tetrahydronaphthalen-2-ol derivatives, to pharmaceutical compositions comprising these compounds and to their use in therapy, in particular to their use for the manufacture of a medicament for the prevention or treatment of lower u...	09/23/2010
20100222438	METHODS COMPOSITIONS AND ARTICLE OF MANUFACTURE FOR MODULATING BONE GROWTH Novel methods and pharmaceutical compositions suitable for modulating bone growth and remodeling, preventing bone diseases, inducing bone growth or repair by cannabinoid receptor-mediated effects on bone cells is disclosed. Methods of identifying bone growth modulating ...	09/02/2010
20100222406	T Type Calcium Channel Blockers and the Treatment of Diseases The present invention provides a method for treating a disease or condition in a mammal associated with influx of extracellular calcium via T type calcium channels, which comprises administering to the mammal a therapeutically effective amount of a T type calcium channe...	09/02/2010
20100196473	Pharmaceutical Composition Containing 6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol with Delayed Active Ingredient Release Pharmaceutical compositions with delayed release which contains 6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol or a pharmaceutically acceptable salt thereof in a matrix with delayed active ingredient release, wherein the matrix contains 1 to 80 wt. % of ...	08/05/2010
20100022631	Treatment of hepatic encephalopathy and liver cirrhosis The compounds D9-tetrahydrocannabinol (THC), cannabidiol (CBD) and capsaicin are useful for prevention, treatment, or both, of hepatic encephalopathy. The compounds capsaicin, 2-arachidonoylglycerol (2-AG), HU-308 and cannabidiol are useful for prevention, treatment, or...	01/28/2010
20090239955	Novel obovatol derivatives or pharmaceutically acceptable salts thereof, preparation method thereof and pharmaceutical composition for the prevention and treatment of cancer containing the same as an active ingredient Disclosed herein are novel obovatol derivatives represented by Chemical Formula 1, and pharmaceutically acceptable salts thereof. Having the ability to inhibit the growth of cancer cells and induce apoptosis in cancer cells, the derivatives or pharmaceutically acceptabl...	09/24/2009
20090215908	TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST The present invention relates to novel synthetic toll like receptor antagonist. The present invention in particular provides compounds, methods and compositions for specifically inhibiting immune stimulation involving TLR ligands, especially TLR-4. The compounds are pot...	08/27/2009
20090175803	METHOD AND COMPOSITIONS FOR ADMINISTERING RESVERATROL AND PTEROSTILBENE Resveratrol and/or pterostilbene are added to a chewable carrier, to enhance absorption of resveratrol and/or pterostilbene buccally or through the mucous membranes of the mouth. The composition containing the resveratrol and/or pterostilbene is designed to be retained ...	07/09/2009
20090170956	PREPARATION AND THE USE OF ETHOXY COMBRETASTATINS AND THEIR PRODRUGS The invention disclosed a total synthesis process of novel ethoxy combretastatins and their prodrugs. Combretastatins are chemically modified by ethoxy substituted on the 4′-position of their B aryl ring and are converted to be their soluble prodrugs of phosphate or t...	07/02/2009
20090130163	Drugs With Improved Hydrophobicity For Incorporation in Medical Devices The invention provides a medical device comprising a hydrophobic analog of a medicament known to inhibit cell proliferation and migration. The invention also provides a method of treating a narrowing in a body passageway comprising placing an implantable medical device ...	05/21/2009
20090098097	COMPOSITION FOR NORMALIZING BLOOD PRESSURE The present invention aims to provide a composition suitable for normalizing the blood pressure, which is useful as food, health food, supplement, nutritional supplement, food for specified health uses, food with nutrient function claims, pharmaceutical product, quasi-d...	04/16/2009
20090069444	Method to Ameliorate Oxidative Stress and Improve Working Memory Via Pterostilbene Administration Disclosed is a pharmaceutical composition for treating oxidative stress comprising a therapeutically effective amount of a substantially pure compound of pterostilbene and a physiologically acceptable carrier. Pterostilbene is administered in an amount between about 2.5...	03/12/2009
20090069387	ANIMAL PARASITE-CONTROL METHOD USING INSECT GROWTH REGULATORS Methods and formulations for treating animal ectoparasites, effective against parasites such as fleas and ticks are provided. The methods comprise topically co-administering a non-mobile insect growth regulator, a mobile insect growth regulator, and an adulticide to the...	03/12/2009
20090036542	Hydroquinone Long-Chain Derivative and/or Phenoxy Long-Chain Derivative and Pharmaceutical Comprising Same The present invention provides compounds represented by formula (1) shown below: (wherein R₁, R₂, R₃, R₄, and R₅are each individually selected from amon...	02/05/2009
20080319071	Novel Nutraceutical and Pharmaceutical Compositions and Use Thereof for the Treatment, Co-Treatment or Prevention of Inflammatory Disorders The present invention relates to new methoxylated aromatic compounds. It also relates to novel compositions comprising methoxylated aromatic compounds as well as to the use of these compositions as a medicament, in particular as a medicament for the treatment, co-treatm...	12/25/2008
20080306165	Compounds for the Treatment of Metabolic Disorders Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, poly-cystic ovary syndrome, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. wherein n is 1 or 2; m ...	12/11/2008
20080306027	Fluoroalkoxycombretastatin Derivatives, Method For Producing the Same and Use Thereof Combretastatin derivatives of formula (I), preparation and use thereof are disclosed, wherein: R_fis alkyl with 1-8 carbon atoms and 1-17 fluorine atoms, R is amino, substituted amino, hydroxyl, nitro, halo, alkyloxy, phosphate or amino acid side chain. Said ...	12/11/2008
20080300304	Ginger Fraction For Inhibiting Human Cyp Enzymes The present invention relates to a process for preparing a ginger fraction, the fraction prepared by this process and the use thereof on its own or combined with drugs for inhibiting human cytochrome P450 (CYP) enzymes (particularly cytochrome P450 3A4, CYP3A4) for posi...	12/04/2008
20080194702	Obovatol Having Anti-Anxiety Activity The present invention relates to obovatol compound isolated from Magnolia obovata Thunb. for the prevention and treatment of anxiety disorders involved with CNS. The obovatol compound isolated from Magnolia obovata Thunb. have potent anti-anxiety activity,...	08/14/2008
20080090909	Ship 1 Modulators The present invention includes the use of pelorol, related compounds and pharmaceutical compositions thereof as modulators of SHIP 1 activity. This invention also provides novel terpene compounds capable of modulating SHIP 1 activity and methods of synthesis thereof. ...	04/17/2008
20070292545	ANTI-INFECTIVE AGENTS AND METHODS OF USE The present invention provides compounds and methods of using of the compounds as anti-infective agents. In a preferred embodiment, the present invention provides wherein R₁is not H when R₂is H and R₂is not H when R₁is H, ...	12/20/2007
20070270490	USE OF (-)(3-TRIHALOMETHYLPHENOXY)(4-HALOPHENYL) ACETIC ACID DERIVATIVES FOR TREATMENT OF INSULIN RESISTANCE, TYPE 2 DIABETES AND HYPERLIPIDEMIA The present invention provides the use of (−)(3-trihalomethylphenoxy)(4-halophenyl)acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes and hyperlipidemia. ...	11/22/2007
20070254952	CANNABINOID RECEPTOR MODULATORS Disclosed are compounds of the formula: or the pharmaceutically acceptable salts or solvates thereof, wherein: Ar¹is a chlorophenyl group, Ar²is a dichlorophenyl group, R¹is a —(CH₂)_m—X—(CH_2<...	11/01/2007
20060293394	Combretastatin analogs with tubulin binding activity Analogs of combretastatin have been discovered which demonstrate impressive cytotoxicity as well as a remarkable ability to inhibit tubulin polymerization. Such compounds are excellent clinical candidates for the treatment of cancer in humans. In addition, certain of th...	12/28/2006
20050277700	Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same A antimicrobial compound, compositions containing the same, and method of using the same for reducing the presence of microorganism on a substrate or in a fluid environment comprising an antimicrobial effective carrier and at least one antimicrobial compounds including ...	12/15/2005
20050165118	Agonists specific for the periperal cannabinoid receptor The invention provides novel pharmaceutical compositions comprising as the active ingredient 4-phenyl pinene derivatives which are specific for the peripheral cannabinoid receptors. In particular, the compounds of the invention binds efficiently to CB2 but do not bind t...	07/28/2005
20050020695	Use of ERbeta-selective ligands for regulating fertility and compounds useful therefor The present invention discloses the use of ERβ-selective ligands for production of medicaments for regulating fertility without additional use of a progestin. ERβ-agonists are used for treatment of infertility and ERβ-antagonists for contraception. ...	01/27/2005

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Class 514/719 - Alicyclic ring