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| Application No. | Application Title | Issue Date |
| 20090285864 | THERAPEUTIC FORMULATION The invention provides compositions and formulations comprising catechol and/or acetogenins and various combinations thereof; including various combinations with other ingredients including botanical preparations containing acetogenin, an extract of green tea or a thera... | 11/19/2009 |
| 20090275665 | Enhanced biological potential of greater than 99% pure form of 1, 7-bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione over corresponding 95% pure form-therapeutic and agricultural applications thereof Disclosed are novel and enhanced anti-fungal properties of greater than 99% pure form of 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione in comparison with the corresponding 95% pure form, said greater than 99% pure form of 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-hep... | 11/05/2009 |
| 20090274746 | METHODS AND COMPOSITIONS FOR CONTROLLED DELIVERY OF PHYTOCHEMICAL AGENTS The presently-disclosed subject matter provides compositions and methods for treating a cancer by providing a composition comprising a biocompatible polymeric matrix incorporating an effective amount of a phytochemical agent, a combination of phytochemical agents, or a ... | 11/05/2009 |
| 20090263492 | Diagnostic Methods and Genetic Markers for Alzheimer Disease Disclosed are methods for identifying individuals suffering from a CNS disorder (including Alzheimer's Disease, behavioral disorders, and the like) that could be treated with a CNS drug with greater therapeutic efficacy and lower side effects and the compounds useful fo... | 10/22/2009 |
| 20090191287 | Mitigation of Inflammation-Related Injuries The present invention comprises formulae and methods that mitigate post-trauma inflammation, thus reducing overall damage to a patient. The formulae includes a uric acid agent, preferably a uric acid inhibitor, along with at least one other compound that is an inflammat... | 07/30/2009 |
| 20090155180 | Methods and targets for identifying compounds for regulating rhinovirus infection The present invention provides methods for identifying genes, expression regulators, receptors, protein product receptors, and proteins that may regulate rhinovirus infections. The genes identified may be used as markers for disease onset and progression and to measure ... | 06/18/2009 |
| 20090142425 | Physiologically active composition A physiologically active composition is claimed which comprises effective amounts of at least one compound from the group 4-O-methyldavidigenin, 4′-O-methyldavidigenin, davidigenin, elemicin, isoelemicin, herniarin, demethoxycapillarisin, in particular 6-demethoxycapi... | 06/04/2009 |
| 20090053203 | Metal-binding therapeutic peptides The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for ... | 02/26/2009 |
| 20090047371 | PHARMACEUTICAL COMPOSITION COMPRISING CURCUMIN AND RESVERATROL AND USES THEREOF IN MEDICAL FIELD The present invention concerns a pharmaceutical composition containing curcumin and resveratrol and its application in the medical field. In particular, the composition according to the invention can be advantageously employed for preventing ageing and vascular diseases... | 02/19/2009 |
| 20090042995 | THERAPEUTIC FORMULATION A pharmaceutical composition including a salt of rhodizonic acid, an OH anion-generating base, a non-toxic acid, a quinone, a salt-containing sulfite, catechol and, optionally, an acetogenin. The formulation demonstrates positive effects against cancer, autoimmune disea... | 02/12/2009 |
| 20090042980 | Neuroprotective compositions and methods Neurite outgrowth-promoting prostaglandins (NEPPs) and other electrophilic compounds bind to Keap1, a negative regulator of the transcription factor Nrf2, and prevent Keap1-mediated inactivation of Nrf2 and, thus, enhance Nrf2 translocation into the nucleus of neuronal ... | 02/12/2009 |
| 20090035362 | Compositions including androgen receptor degradation (ARD) enhancers and methods of prophylactic or therapeutic treatment of skin disorders and hair loss The present invention includes methods and compositions useful for treating and preventing skin disorders, hair loss and other skin disorders. The compositions include an ARD enhancer in combination with a second compound or composition. In some embodiments the second c... | 02/05/2009 |
| 20090018209 | CURCUMIN AND CURCUMINOID INHIBITION OF ANGIOGENESIS Methods for treating diseases or disorders of the skin which are characterized by angiogenesis have been developed using curcumin and curcumin analogs. Based on the results obtained with curcumin, it has been determined that other angiogenesis inhibitors can also be use... | 01/15/2009 |
| 20080312186 | KETONES AND REDUCED KETONES AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE CONDITIONS The present invention pertains to certain ketones and reduced ketones and derivatives thereof which, inter alia, inhibit osteoclast survival, formation, and/or activity; and/or inhibit bone resorption, and more particularly to compounds of the formulae and pharmaceutica... | 12/18/2008 |
| 20080293684 | Heterocyclic Acetophenone Potentiators of Metabotropic Glutamate Receptors The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction ... | 11/27/2008 |
| 20080160007 | Diagnosis and treatment of cancer related to human dormancy New devices and methods for diagnosis and compositions and methods for treatment of cancers use combinations of antimicrobial agents and agents that can reverse dormancy and hibernation pathways. We unexpectedly found that surprisingly low doses of anti-hibernation comp... | 07/03/2008 |
| 20080161391 | NOVEL CURCUMIN ANALOGUES AND USES THEREOF The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment... | 07/03/2008 |
| 20080146660 | NOVEL CURCUMIN ANALOGUES AND USES THEREOF The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment... | 06/19/2008 |
| 20080146669 | Novel Chloride Channel Pore Openers Described is a method for treating and/or preventing disease states and conditions associated with defects in the activity of chloride channels, such as the CFTR channel. The present disclosure also described compounds useful in such treatment and prevention methods and... | 06/19/2008 |
| 20080139496 | COMBINATION THERAPY FOR REDUCTION OF TOXICITY OF CHEMOTHERAPEUTIC AGENTS There are provided compositions, pharmaceuticals formulations and kits for treating neoplasms and tumours, viral infections, bacterial infections or parasite infections. There are also provided compositions, pharmaceutical formulations and kits for suppression of immune... | 06/12/2008 |
| 20080138400 | LIPOSOMAL CURCUMIN FOR TREATMENT OF DISEASES The present invention provides compositions and methods for the treatment of a human patient. The methods and compositions of the present invention include composition for the efficient loading of curcumin, comprising: an amount of a curcuminoid:liposome complex effecti... | 06/12/2008 |
| 20080124346 | Metal-binding therapeutic peptides The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for ... | 05/29/2008 |
| 20080103213 | LIPOSOMAL CURCUMIN FOR TREATMENT OF NEUROFIBROMATOSIS The present invention provides a compositions and methods for the treatment of Neurofibromatosis Type 1 and 2, in a human patient. The methods and compositions of the present invention employ curcumin or a curcumin analogue encapsulated in a colloidal drug delivery syst... | 05/01/2008 |
| 20080103160 | Protein phosphatase inhibitors A method of inhibiting protein tyrosine phosphatase in a subject includes administering to the subject a therapeutically effective amount of at least one benzo-1,4-quinone, phenyl isothiazolone, or analog thereof to the subject. ... | 05/01/2008 |
| 20080075671 | INTRANASALLY ADMINISTERING CURCUMIN TO THE BRAIN TO TREAT ALZHEIMER'S DISEASE The present invention relates to intranasally administering a pharmaceutical composition comprising curcumin to an upper third of a nasal cavity of the mammal, wherein the curcumin is absorbed through a nasal mucosa and transported to the brain of the mammal.... | 03/27/2008 |
| 20080069900 | Combination chemotherapy compositions and methods This invention relates to combination therapies involving anticancer chemotherapeutic agents and isoflavones or analogues thereof. The invention flier relates to compounds, compositions, methods and therapeutic uses involving, containing, comprising, including and/or fo... | 03/20/2008 |
| 20080051464 | Protein phosphatase inhibitors A method of inhibiting protein tyrosine phosphatase in a subject includes administering to the subject a therapeutically effective amount of at least one benzo-1,4-quinone, phenyl isothiazolone, or analog thereof to the subject. ... | 02/28/2008 |
| 20080045604 | COMPOSITION AND METHOD FOR FACILITATING THE HEALING OF NON-HEALING AND SLOW-HEALING WOUNDS AND ULCERATIONS The invention is of a composition for treatment of non-healing and slow-healing wounds and ulcerations, and for treating and preventing peripheral neuropathy. The composition is primarily characterized by a combination of nitroglycerin and turmeric. Preferred embodiment... | 02/21/2008 |
| 20080039393 | Metal-binding therapeutic peptides The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for ... | 02/14/2008 |
| 20080033055 | Method for the Synthesis of Curcumin Analogues The present invention relates to improved methods for achieving the synthesis of 1,7-diaryl-1,6-heptadiene-3,5-diones, and in particular curcumin and its analogues. The invention provides a process for synthesizing such compounds in substantial yield and purity using en... | 02/07/2008 |
| 20080020998 | Sustained release compositions for the therapeutic management of pain, inflammation and inflammation-associated disorders and prophylactic/ therapeutic methods thereof Disclosed are sustained-release medicaments/drug compositions/formulations/therapeutics for the management of pain and inflammation associated disorders in general, more particularly arthritic inflammation. The sustained-release compositions comprise effective amounts o... | 01/24/2008 |
| 20070249596 | ABNORMAL CANNABIDIOLS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I | 10/25/2007 |
| 20070225377 | Bridged Ring Structures as Pharmaceutical Agents The present invention is directed to 1α,25-dihydroxyvitamin D3 mimics which modulate the vitamin D receptor (VDR). The invention is further directed to pharmaceutical compositions and methods for the treatment, prevention or amelioration of one or more symptoms of dise... | 09/27/2007 |
| 20070060644 | Therapeutic curcumin derivatives Curcumin analogues and methods are provided for treatment of disease. ... | 03/15/2007 |
| 20060280746 | Alpha, beta-unsaturated sulfoxides for treating proliferative disorders αβ-Unsaturated sulfoxides of Formula I: are useful as antiproliferative agents including, for example, anticancer agents, and as radioprotective and chemoprotective agents. ... | 12/14/2006 |
| 20060276536 | Cancer treatment using curcumin derivatives Cancer or a precancerous condition is treated by administering a curcumin derivative to a subject. ... | 12/07/2006 |
| 20060199768 | Inhibitors of RecA activities for control of antibiotic-resistant bacterial pathogens Compounds for modulating RecA protein activity are provided. In some embodiments, the compounds modulate RecA activity by interfering with assembly of monomeric RecA protein subunits into a nucleoprotein filament. In some embodiments, the compounds modulate RecA activit... | 09/07/2006 |
| 20060189549 | Chalcone derivatives and their use to treat diseases The invention relates to compounds, pharmaceutical compositions and methods of using compounds of the general formula or its pharmaceutically acceptable salt or ester, wherein the substituents are defined in the application. ... | 08/24/2006 |
| 20060148905 | Methods for treatment of beta-amyloid protein-induced ocular disease The invention provides methods for treating beta-amyloid protein-involved ocular disease including age-related macular degeneration and glaucoma, pharmaceutical compositions and compounds useful for the same, and the use of these compounds for the manufacture of a medic... | 07/06/2006 |
| 20060127349 | Novel of preparation hypericin bonded with poly-n-vinylamides The invention relates to an active agent combination for diagnosing and treating tumours, comprising a water-soluble complex or a water-soluble compound of pure hypericin and a poly-N-vinylamide, especially PVP. ... | 06/15/2006 |
