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| Application No. | Application Title | Issue Date |
| 20110251146 | TOPICAL ANTIFUNGAL COMPOSITION A topical, foamable composition is provided that includes at least one antifungal agent that is able to penetrate the upper layers of skin and is retained in or on an area to be treated for a prolonged period of time, and that has a residual non-volatile component conte... | 10/13/2011 |
| 20110189257 | NANOPARTICLE BASED THERAPY FOR AGGREGATING MUCIN There are provided compositions and methods to aggregate mucus using a plurality of positively charged nanoparticles. There are also provided compositions and methods for inducing contraception in the subject.... | 08/04/2011 |
| 20110142799 | MODULATION OF NEURODEGENERATIVE DISEASE BY MODULATING XBP-1 ACTIVITY The invention provides methods for treating and preventing a neurodegenerative disease associated with aberrant protein aggregation by modulating the expression and/or activity of XBP-1, IRE-1 alpha, and/or EDEM. The present invention also pertains to methods for identi... | 06/16/2011 |
| 20110104308 | Treatment For Diseases Relying On Discovery That Thioredoxin Mediates Nitric Oxide Patients having a disease associated with high level of thioredoxin system activity or a requirement for nitric oxide, e.g. large cell lymphoma or restenosis, are treated with a thioredoxin reductase inhibitor, e.g. auranofin or arsenic trioxide, and a nitric oxide dona... | 05/05/2011 |
| 20110064720 | Dietary Supplement Compositions and Methods of Making and Using the Same Dietary supplement compositions are disclosed. Methods of making and using dietary supplement compositions are also disclosed.... | 03/17/2011 |
| 20110008469 | ANTIMICROBIAL COMPOSITION AND METHODS AND APPARATUS FOR USE THEREOF There is presented an alkaline disinfectant in the form of a multi-component composition, with each component being relatively benign until mixed with the other components in a ready-to-use solution. The invention further relates to the use of the composition in a varie... | 01/13/2011 |
| 20100317741 | METHOD FOR TREATING SEPTIC SHOCK OR ENDOTOXEMIA The invention provides a method for treating septic shock or endotoxemia, which comprises administering to a subject a therapeutically effective amount of a pharmaceutical composition comprising formula I, II, III or IV and their salt, ester or solvate thereof.... | 12/16/2010 |
| 20100280452 | MEDICAL DEVICES HAVING MULTIPLE LAYERS Described herein are medical devices which are configured for implantation or insertion into a subject, preferably a mammalian subject. The medical devices contain one or more multilayer regions, which contain: (a) one or more (typically a plurality of) charged nanopart... | 11/04/2010 |
| 20100227931 | ANTIFUNGAL COMPOSITION The present invention provides the antifungal composition, containing the compound (a) selected from specific quaternary ammonium salts and specific amine oxides and the sequestering agent (b) having a calcium-chelating constant of 4 to 12 at a mass ratio (a)/(b) of 0.0... | 09/09/2010 |
| 20100160300 | Method of Treating Depression Methods for treatment of depression-related mood disorders in mammals, particularly humans are disclosed. The methods of the invention include administration of compounds capable of enhancing glutamate transporter activity in the brain of mammals suffering from depressi... | 06/24/2010 |
| 20100150898 | COMPOUNDS AND METHODS FOR THE TREATMENT OF AIRWAY DISEASES AND FOR THE DELIVERY OF AIRWAY DRUGS Chronic obstructive airway diseases are treated by administering an osmotically active compound such as a salt, sugar, sugar alcohol, or organic osmolyte to the afflicted airway surface. The compound may be administered as a liquid or dry powder aerosol formulation. Dis... | 06/17/2010 |
| 20100047198 | Textile Scenting A perfume-containing PIT emulsion which is suited to contribute to an excellent and long-lasting scenting of textiles during the use of a dryer. The PIT emulsion is simple for the user to handle and allows the user to better control the user's individual scent experienc... | 02/25/2010 |
| 20100041622 | Compositions containing aminoalkanes and aminoalkane derivatives Provided are palatable liquid compositions that contain 2-aminoalkanes that have vasoconstrictor activity, and other additives, including taste-modifying agents. Also provided are methods for making and using the compositions to provide stimulant activity for increasing... | 02/18/2010 |
| 20100040594 | FORMULATIONS FOR NONSURGICAL EXOGENOUS CROSSLINK THERAPY Improved methods and compositions for the treatment of native tissues with crosslinkers are provided. The methods and compositions will find particular use in increasing resistance to tearing, fissuring, rupturing, and/or delamination.... | 02/18/2010 |
| 20100015250 | Thermally Stable Subsea Control Hydraulic Fluid Compositions An aqueous hydraulic fluid composition comprising of one or more lubricants such as a monovalent metal salt, ammonium, or alkanolamine salt of a dicarboxylic acid, such as a C21 dicarboxylic acid is described in which the aqueous hydraulic fluid composition demonstrates... | 01/21/2010 |
| 20090318403 | ANTIBIOTIC COMPOSITION The present invention provides antimicrobial compositions comprising an antibiotic and a sensitizer that enhances the effectiveness or activity of the antibiotic, wherein the sensitizer is preferably a primary amine containing a long alkyl chain. Such compositions are p... | 12/24/2009 |
| 20090291919 | Compositions and Methods for Treating or Preventing Ophthalmic Light Toxicity Methods are disclosed for treating ophthalmic conditions related to the production of toxic visual cycle products that accumulate in the eye, and are associated with reactions of the visual cycle during medical procedures that expose the eye to light, most commonly the ... | 11/26/2009 |
| 20090130475 | Wood treatment solution and process The present invention features a single aqueous solution that imparts acceptable levels of water resistance, fire resistance, mold resistance and pest resistance to wood, and which may be used in standard wood treatment techniques commonly utilized in the wood treatment... | 05/21/2009 |
| 20080194526 | Liquid Formulations Disclosed is a concentrate for dilution comprising a S1P receptor agonist or a pharmaceutically acceptable salt thereof, propylene glycol and optionally glycerin. This formulation is adapted for patients in a difficult condition to swallow.... | 08/14/2008 |
| 20080125494 | ALKYLAMINE AS AN ANTIMICROBIAL AGENT IN OPHTHALMIC COMPOSITIONS A multi-purpose contact lens care solution having high activity against fungi and certain bacteria comprising, in liquid aqueous medium, an alkylamine having the following formula, where R1 is a C13-17 <... | 05/29/2008 |
| 20080044461 | Transdermal methods and systems for treating Alzheimer's disease Transdermal delivery systems for delivery of Alzheimer's pharmaceuticals, particularly donepezil, over one to seven days are disclosed which deliver the free-base form of the Alzheimer's pharmaceutical at a skin permeation rate such that blood levels of the Alzheimer's ... | 02/21/2008 |
| 20080008752 | Pharmaceutical compositions of memantine The invention is directed to easily dissolved, stable dose proportional pharmaceutical compositions, comprising granulated memantine and methods of preparing the same. In particular, the invention is directed to granulated memantine pharmaceutical compositions in the fo... | 01/10/2008 |
| 20070297981 | Formulations and methods for treating dry eye The present invention provides compositions for treating and/or preventing signs and symptoms associated with dry eye and/or ocular irritation, and methods of use thereof. Such compositions are provided in novel ophthalmic formulations that are comfortable upon instilla... | 12/27/2007 |
| 20070259028 | Percutaneous absorption preparations of antidementia drugs Disclosed is a percutaneous absorption preparation which enables the stable administration of an antidementia drug over a long period of time. More particularly, the percutaneous absorption preparation of the antidementia drug which is used as a plaster on skin comprise... | 11/08/2007 |
| 20070238780 | Multifunctional enhancement systems for personal care, household, and wood products A personal care product, a household product, an industrial formulation, or a medicinal product of at least a fluorosurfactant and/or a natural or naturally-derived or synthetic, and/or *Eco-friendly (See Description) materials such as PEG-4 rapeseedamide, glycerth 2-co... | 10/11/2007 |
| 20070219157 | COMPLETE NUTRIENT MEDIUM FOR USE AS A COSMETIC AND COSMETIC USE THEREOF A cosmetic composition contains an aqueous complex nutritive base comprising a plurality of amino acids, at least one vitamin, a plurality of assimilable organic components, and at least one inorganic salt. The cosmetic composition does not contain a biological extract ... | 09/20/2007 |
| 20070208082 | POLYAMINES USEFUL AS ANTI-PARASITIC AND ANTI-CANCER THERAPEUTICS AND AS LYSINE-SPECIFIC DEMETHYLASE INHIBITORS Polyamine, polyamine/guanidino, and polyamine/biguanide compounds are disclosed. The compounds are useful as anti-cancer and anti-parasitic treatments. The compounds are also useful as inhibitors of the enzyme lysine-specific demethylase-1. ... | 09/06/2007 |
| 20070059259 | Compositions and methods for mitigating skin irritation The invention relates to a composition and a method for mitigating redness or inflammation of mammalian skin comprising administering to mammalian skin a composition consisting of an effective amount of alkanolamine, feverfew or soy or mixtures thereof, one or more opti... | 03/15/2007 |
| 20070031516 | Composition for the prevention and treatment of cellulitis The invention relates to a composition for preventing and treating cellulite, characterized in that it comprises ingredients with lipolytic and venotonic effects, preferably a mixture of caffeine, dry butcher's broom extract (Ruscus Aculeatus), triethanolamine hy... | 02/08/2007 |
| 20060293393 | Iptakalim hydrochloride for decreasing nicotine use A method for decreasing nicotine and other substance use in humans is disclosed. Iptakalim hydrochloride (IPT) is a novel nicotine acetylcholine receptor (nAChR) blocker. According to the disclosed method, IPT is used to block human α4β2-nAChR function. Specifically, ... | 12/28/2006 |
| 20060287403 | Method and Composition for Treatment of Inflammatory and Inflammation-related Disorders A method of reducing inflamation in a variety of disorders by using an intraperitoneal solution of magnesium. The solution can be used for treating inflammatory and inflammation-related disorders in animals and/or humans. Application of the solution reduces inflammation... | 12/21/2006 |
| 20060287402 | Cathepsin inhibitors This invention relates to a novel class of compounds, represented by the formula (I) below, wherein the meanings of R1, R2, R3 and R4 are indicated therein, which are cysteine protease inhibitors, including but not limited to,... | 12/21/2006 |
| 20060280730 | INDUCTION OF APOPTOSIS OF MALIGNANT CELLS BY ACTIVATION OF CALCIUM-ACTIVATED POTASSIUM CHANNELS Disclosed are a method of inducing apoptosis of a malignant cell, which employs a calcium-activated potassium channel (KCa) activator and is useful for treating a malignant tumor in a human subject. Also disclosed are methods of selectively inhibiting the pro... | 12/14/2006 |
| 20060276551 | Exo-S-Mecamylamine Formulation and Use in Treatment A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof substantially free of exo-R-mecamylamine in combination with a pharmaceutically acceptable carrier. Preferably the amount is abou... | 12/07/2006 |
| 20060270647 | Glutamate agents in the treatment of mental disorders Methods of treating mental disorders, including anxiety disorders such as obsessive-compulsive disorder, are provided. The methods comprise administering an effective amount of a glutamate modulator to an individual in need thereof. Also provided are methods of enhancin... | 11/30/2006 |
| 20060270742 | Compositions and methods for the treatment of neurodegenerative diseases The invention features compositions and methods for the treatment of neurodegenerative diseases. ... | 11/30/2006 |
| 20060251717 | Memantine Oral Dosage Forms This invention relates to an oral dosage form containing between 1 mg and 100 mg of memantine, wherein said dosage form does not contain 10 mg of memantine or 20 mg of memantine, and wherein said dosage form is not prepared by the patient or a person administering the d... | 11/09/2006 |
| 20060252788 | Methods and compositions for the treatment of CNS-related conditions The present invention provides novel methods and compositions for the treatment and prevention of CNS-related conditions. One of the CNS-related conditions treated by the methods and compositions of the invention is Alzheimer's disease. ... | 11/09/2006 |
| 20060247161 | Use of active ingredients for the prophylaxis and/or therapy of viral diseases The invention relates to the use preferably of at least one active ingredient for the prophylaxis and/or therapy of a viral disease, wherein this active ingredient inhibits at least one component of the cellular signal transduction pathway for the activation of the tran... | 11/02/2006 |
| 20060240043 | Methods and compositions for treating migraine pain The present invention provides novel methods and compositions for the treatment and prevention of headaches, vascular headaches, migraine headaches, cluster headaches, and migraine. One of the headaches, vascular headaches, migraine headaches, cluster headaches, and mig... | 10/26/2006 |