Did You Know...
...that power steering was invented by independent inventor Francis W. Davis? As chief engineer in the 1920s of the truck division of the Pierce Arrow Motor Car Company, he saw how hard it was to steer heavy vehicles. So that he would be able to keep the profits from his future invention, Davis left his job, rented a small engineering shop in Waltham, Mass., and developed a hydraulic power steering system that led to power steering.
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| Application No. | Application Title | Issue Date |
| 20120128793 | IMPLANTABLE OR INSERTABLE MEDICAL DEVICE RESISTANT TO MICROBIAL GROWTH AND BIOFILM FORMATION Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or in... | 05/24/2012 |
| 20120083534 | OPHTHALMIC AND CONTACT LENS SOLUTION An ophthalmic solution comprising a polyethoxylated glyceride in the range of 0.001 to about 10 percent by weight and a buffer agent. These solutions impart surprising comfort and wearability to contact lenses. At the same time the solutions provide good preservative ca... | 04/05/2012 |
| 20120083515 | BIOADHESIVE GEL BASED ON HYDROXYETHYLCELLULOSE Disclosed are compositions in the form of a bioadhesive gel that adheres to the mucous membranes, in particular the vaginal mucosa, for the application of active ingredients and/or principles, comprising hydroxyethylcellulose as the only gelling agent.... | 04/05/2012 |
| 20120071525 | ANTI-MICROBIAL COMPOSITION The present invention provides an anti-microbial composition comprising (i) an antimicrobial agent with surfactant properties, (ii) a siloxane selected from those having the formulae V:(H3C)[SiO(CH3)2]nSi(CH3)3... | 03/22/2012 |
| 20120071438 | ANTIMICROBIAL COMPOSITIONS CONTAINING CATIONIC ACTIVE INGREDIENTS AND QUATERNARY SUGAR DERIVED SURFACTANTS The antimicrobial composition of the present invention comprises a cationic active ingredient, a quaternized sugar-derived surfactant, and an optional foam boosting surfactant. These formulations have a high cidal activity in a short amount of time and provide stable co... | 03/22/2012 |
| 20120070341 | ANTIMICROBIAL COMPOSITIONS CONTAINING CATIONIC ACTIVE INGREDIENTS AND QUATERNARY SUGAR DERIVED SURFACTANTS The antimicrobial composition of the present invention comprises a cationic active ingredient, a quaternized sugar-derived surfactant, and an optional foam boosting surfactant. The present antimicrobial compositions are free of the antimicrobial agent triclosan (i.e., 2... | 03/22/2012 |
| 20120052292 | NOVEL MEDICAL DEVICE COATINGS The present invention relates to coatings comprising polyethylene glycol and at least one polyphenolic polymer. In particular, the polyphenolic polymer could be selected from the group consisting of tyrosine-derived polyarylates, linear polyesteramides, dihydroxybenzoat... | 03/01/2012 |
| 20120046556 | Methods and Kits for Preventing the Spread of Sexually Transmitted Microorganisms This application is directed to methods and kits for preventing the spread of sexually transmitted microorganisms among individuals. The present method is for the application of a medicament comprising an irrigant to an area of the body having, or which may have, a lesi... | 02/23/2012 |
| 20120041070 | METHODS OF TREATING CANCER HAVING AN ABERRANT EGFR OR KRAS GENOTYPE The invention relates to the treating cancer having an aberrant EGFR or KRAS genotype, with an AMPK activator, as well as related methods, compounds and compositions.... | 02/16/2012 |
| 20120041069 | SGLT2 INHIBITOR DOSAGE FORMS A pharmaceutical composition comprising a sodium-dependent glucose transporter (SGLT2) inhibitor and a biguanide, wherein at least one of the active agents is in slow release form, is provided. A method for treating diabetes in a patient in need thereof including admini... | 02/16/2012 |
| 20120035116 | BILE ACIDS AND BIGUANIDES AS PROTEASE INHIBITORS FOR PRESERVING THE INTEGRITY OF PEPTIDES IN THE GUT This invention relates to methods of preserving the integrity of peptides in the gut. In particular it concerns the use of certain compounds as inhibitors of gut proteases. Compounds identified as having gut protease inhibitory activity are biguanides, certain bile acid... | 02/09/2012 |
| 20120021049 | Single Daily Dosage Form for Prevention and Treatment of Metabolic Syndrome The present invention is in the fields of medicine, pharmaceuticals, nutraceuticals, endocrinology and cardiology. The invention provides compositions comprising a statin, an inhibitor of the angiotensin converting enzyme, an antiplatelet compound and an anti-hyperglyce... | 01/26/2012 |
| 20120010213 | ORAL CONTROLLED RELEASE DOSAGE FORMS FOR WATER SOLUBLE DRUGS Disclosed herein is an oral controlled release pharmaceutical formulation comprising water-soluble drug or pharmaceutically acceptable salts thereof, in a hydrophilic matrix system, further comprising pH independent polymers present in an amount of 5% to 90% w/w in comb... | 01/12/2012 |
| 20120004271 | USE OF VAGINALLY-ADMINISTERED INSULIN SENSITIZING AGENTS Use of vaginal insulin sensitising agents for the prevention and/or treatment of hyperandrogenism and/or polycystic ovary syndrome and/or related disorders.... | 01/05/2012 |
| 20110311594 | CONTROLLED RELEASE COMPOSITIONS WITH REDUCED FOOD EFFECT The present invention provides a controlled release pharmaceutical composition which exhibits reduced food effect.... | 12/22/2011 |
| 20110311629 | NON-ADHESIVE ELASTIC GELATIN MATRICES The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s... | 12/22/2011 |
| 20110305733 | PHARMACEUTICAL FORMULATIONS COMPRISING METFORMIN AND A FIBRATE, AND PROCESSES FOR OBTAINING THEM The present invention relates to granulates comprising particles of metformin and particles of a fibrate. The invention further relates to pharmaceutical compositions containing such granulates. The invention also relates to processes for preparing said granulates and s... | 12/15/2011 |
| 20110300137 | Use of lumefantrine and related compounds in the treatment of cancer The present application discloses the use of the anti-malarial drug lumefantrine and related compounds in the treatment of cancer.... | 12/08/2011 |
| 20110293556 | TREATMENT OF INSULIN RESISTANCE/METABOLIC SYNDROME TO ALLEVIATE THE RISKS OF DEMENTIA This invention relates to Applicant's discovery that Metabolic Syndrome , a cluster of disorders stemming from a resistance to insulin, contributes directly to dementia, particularly Alzheimer's disease. Applicant's invention includes a screening method to determine sus... | 12/01/2011 |
| 20110286927 | ATF4 Inhibitors and Their Use for Neural Protection, Repair, Regeneration, and Plasticity In one aspect, the invention relates to a method for identifying a drug candidate with activity as a neuroprotective agent. The method includes determining whether a compound reduces ATF4 activity; and identifying the compound that reduces ATF4 activity as a drug candid... | 11/24/2011 |
| 20110287083 | Bioabsorbable Composition and Coatings Including Same Bioabsorbable compositions of A) blends of bioabsorbable homopolymers and/or copolymers containing glycolide and lactide and B) salts of fatty acids and/or fatty acid esters are described. Processes for making the compositions and surgical articles made totally or in pa... | 11/24/2011 |
| 20110281829 | NOVEL COMPOSITION This disclosure relates to a pharmaceutical composition that includes a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an adenosine 5′-monophosphate-activated protein kinase (AMPK) activator; a second agent ... | 11/17/2011 |
| 20110263717 | Ophthalmic Compositions with Biguanide and PEG-Glycerol Esters Ophthalmic compositions that comprise 0.1 ppm to 2 ppm of poly(hexamethylene biguanide); and 0.005 wt. % to 0.3 wt. % of a PEG-glycerol ester of general formula I
| 10/27/2011 |
| 20110263665 | FORMULATIONS COMPRISING AN ANTI-MICROBIAL COMPOSITION The present invention describes a formulation comprising: (A) at least one surfactant; and (B) an anti-microbial composition that comprises (i) an anti-microbial agent with surfactant properties; (ii) a hydrophobic material and (iii) a polar solvent.... | 10/27/2011 |
| 20110251285 | COMBINATIONS OF PRESERVATIVES FOR OPHTHALMIC COMPOSITIONS The present invention provides a preservative composition for protecting ophthalmic solutions from microbial attack comprising a combination of benzalkonium ion and polyhexamethylene biguanide (PHMB) wherein the combined concentrations of benzalkonium ion and polyhexame... | 10/13/2011 |
| 20110244062 | MULTIPLICATION OF THE EFFICACY OF ANTI-INFECTIOUS AGENTS BY A COMPOSITION COMPRISING AN EXTRACT MADE FROM DEHYDRATED AND PARTIALLY SODIUM-FREE SEAWATER The present invention relates to a composition inhibiting or destroying at least one living or unicellular organism, which comprises at least one anti-infectious agent and one activating agent, which consists of an extract made from dehydrated and partially sodium-free ... | 10/06/2011 |
| 20110245317 | USE OF ORGANIC COMPOUNDS This application is directed to methods for improving glucose control by administering metformin in combination with a DPP-IV inhibitor to a patient in need thereof, in an amount sufficient to control the glucose level over an extended period of time.... | 10/06/2011 |
| 20110245324 | ANTIMICROBIAL COMPOUNDS The present invention relates to compounds that modulate the shikimate pathway and/or a pathway branching from the shikimate pathway in members of the Amoebida Order. In particular these compounds may be useful in the treatment or prevention of diseases caused or contri... | 10/06/2011 |
| 20110236477 | PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL DOSAGE FORM, PROCESS FOR THEIR PREPARATION, METHODS FOR TREATING AND USES THEREOF The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a SGLT-2 inhibitor drug and a partner drug, processes for the preparation thereof, and their use to treat certain diseases.... | 09/29/2011 |
| 20110236485 | SHELL AND CORE DOSAGE FORM APPROACHING ZERO-ORDER DRUG RELEASE Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also motes gas... | 09/29/2011 |
| 20110229418 | Compositions and Methods of Treating and Preventing Lung Cancer Compositions and methods for treating and preventing cancer, particularly lung cancer, are provided.... | 09/22/2011 |
| 20110229569 | COMPOSITIONS EXHIBITING DELAYED TRANSIT THROUGH THE GASTROINTESTINAL TRACT The present invention provides a composition exhibiting delayed transit through the gastrointestinal tract comprising one or more active agents, fenugreek fiber and at least one pharmaceutically acceptable excipient. The present invention further relates to gastroretent... | 09/22/2011 |
| 20110223111 | CALCIUM CARBONATE MICROSTRUCTURES USEFUL IN ENCAPSULATION APPLICATIONS AND A PROCESS FOR THE PREPARATION THEREOF A facile method to synthesize stable calcium carbonate microstructures is demonstrated which allows in situ encapsulation of sensitive molecules like drugs. The methodology involves a macromolecular assembly of anionic polypeptide with cationic peptide oligomer to concu... | 09/15/2011 |
| 20110217374 | PHARMACEUTICAL COMPOSITION SIMULTANEOUSLY HAVING RAPID-ACTING PROPERTY AND LONG-ACTING PROPERTY Disclosed is a pharmaceutical composition simultaneously having a rapid acting property and a long-acting property, comprising a sustained-release part coated with a water-insoluble polymer on the surface, comprising a first active pharmaceutical ingredient, at least on... | 09/08/2011 |
| 20110218142 | Inhibitors of Dipeptidylpeptidase IV The present invention relates to inhibitors of post-proline cleaving enzymes, such as inhibitors of dipeptidyl peptidase IV, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. In particular, the inhibitors of the present invention are... | 09/08/2011 |
| 20110218209 | NUTRIENT DELIEVRY DRUG COMPOSITION The present invention is a hypoallergenic nutrient delivery drug composition, that includes an active drug, a binder with non-genetically engineered and non-chemically treated starches and food powders, a filler with non-genetically engineered and non-chemically treated... | 09/08/2011 |
| 20110207826 | LACTOSE AND CELLULOSE-BASED TABLETING AID The present invention concerns a process for producing a granulate based on lactose and cellulose (derivative), a granulate obtainable by the process and its use as a tabletting excipient.... | 08/25/2011 |
| 20110206770 | ATOVAQUONE WITH A PARTICLE SIZE DIAMETER RANGE (D90) OF GREATER THAN 3 MICRONS TO ABOUT 10 MICRONS Atovaquone or a pharmaceutically acceptable salt thereof having a particle size diameter range with a D90 of between greater than 3 to about 10 μm.... | 08/25/2011 |
| 20110195119 | CONTROLLED RELEASE METFORMIN FORMULATIONS Sustained release pharmaceutical formulations comprising an antihyperglycemic drug or a pharmaceutically acceptable salt thereof are disclosed. The formulations provide therapeutic plasma levels of the antihyperglycemic drug to a human patient over a 24 hour period afte... | 08/11/2011 |
| 20110189160 | Veterinary Topical Agent Methods and compositions for treating skin conditions in animals, which tend to have higher skin pH than humans, including wounds, ulcers, rashes, burns, abrasions, and other irritations and relevant injuries are provided. The invention contemplates the use of an aqueou... | 08/04/2011 |
