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Class 514/627 - Carbon to carbon unsaturation in R


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the carboxylic acid residue (R) contains
No. of applications: 114
Last issue date: 03/22/2012


1      
Application No.Application TitleIssue Date
20120071417METHODS OF INHIBITING CANCER CELL GROWTH WITH HDAC INHIBITORS AND METHODS OF SCREENING FOR HDAC10 INHIBITORS
Methods of inhibiting cancer cell growth using HDAC10 inhibitors are provided. Methods of treating cancer in a subject using HDAC10 inhibitors are also provided. In certain embodiments, at least one second inhibitor selected from an autophagy inhibitor, an AMPK inhibito...
03/22/2012
20120070507Compositions and Methods for the Treatment of Soft Tissue Injury
Provided herein are compositions and methods for the treatment of soft tissue injury, sports-related injury, physical overuse of muscles, ligaments or joints, and trauma, traumatic stress or sudden jolts on bones and tissues in an individual. Described herein are pharma...
03/22/2012
20120040021METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
The invention relates to compositions comprising an acid ceramidase inhibitor and a choline kinase inhibitor as well as to the uses thereof for the treatment of cancer. The invention also relates to methods for the selection of an individualised therapy of a cancer pati...
02/16/2012
20120027693METHODS AND COMPOSITIONS FOR PREVENTING AND RELIEVING MUSCLE CRAMPS AND FOR RECOVERY FROM NEUROMUSCULAR IRRITABILITY AND FATIGUE FOLLOWING EXERCISE
The methods and compositions of the present invention are directed to the treatment or amelioration of muscle cramps using a composition that includes one or more TRPV1 channel activators, and/or one or more TRPA1 channel activators, and/or one or more ASIC channel acti...
02/02/2012
20120028906METHOD FOR AFFECTING THE TIMING OF CERVICAL RIPENING AND FOR PARTURITION
A method for affecting the timing of cervical ripening and the resultant onset of parturition in a pregnant female mammal, the method comprises administering to a pregnant female one or more than one dose of an agent that chemically mimics innervation of the cervix by t...
02/02/2012
20120022105GREASE-LIKE GEL FOR REPELLING RODENTS
Grease-like compositions are provided for repelling rodents. The compositions utilize nontoxic mineral, synthetic, or vegetable oil based gels containing silica, clay, urea, polytetrafluoroethylene, or metallic soap thickeners and capsaicin....
01/26/2012
20120022165TRANSDERMAL COMPOSITIONS
The present invention is directed to transdermal compositions and the uses thereof. These compositions include at least one of the following components: a C1-C6 dialkyl, C12-C30 dialkyl quaternary ammonium salt, a C12
01/26/2012
20120016032Cosmetic Composition Containing Calcium Citrate And N-Acylated Aminoalcohol Derivative To Prevent Dry Skin And Signs Of Cutaneous Ageing
Cosmetic compositions comprising calcium citrate and at least one N-acylated aminoalcohol according to formula (I).

Provided is a method of treating aged skin, comprising topically applying to the aged skin a...

01/19/2012
20120009240Films for Delivery of a Therapeutic Agent
The present disclosure relates to self-supporting films for delivery of a therapeutic agent containing at least one hydrophobic polymer and at least one therapeutic agent. Methods of forming the multilayer films are also disclosed....
01/12/2012
20110313047DELIVERY SYSTEM FOR HIGH CONCENTRATION OF CERAMIDE
The present invention is directed to a delivery system capable of solubilizing high concentrations of ceramide, the system containing: (a) at least one C1-C4 monoalcohol; (b) at least one C6-C22 fatty acid and/or alcohol; and (c) from about 5 to about 14% by weight, bas...
12/22/2011
20110301078PREVENTION OF BACTERIAL GROWTH AND BIOFILM FORMATION BY LIGANDS THAT ACT ON CANNABINOIDERGIC SYSTEMS
A group of antimicrobial compounds shows effectiveness for preventing bacterial growth and bio film formation. In particular, the compounds are effective for preventing the growth of gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (...
12/08/2011
20110256510Use of Quaternary Ammonium Compounds to Inhibit Endogenous MMPs in Tooth Dentin
Disclosed are compositions and methods of using such compositions for inhibiting matrix metalloproteinase activity in dental tissue. The compositions, methods and uses may prevent degradation of the bonding between restorative materials and dental tissues, thereby incre...
10/20/2011
20110251241GREASE-LIKE GEL FOR REPELLING RODENTS
Grease-like compositions are provided for repelling rodents. The compositions utilize nontoxic mineral, synthetic, or vegetable oil based gels containing silica, clay, urea, polytetrafluoroethylene, or metallic soap thickeners and capsaicin....
10/13/2011
20110236459Therapeutic Implant
Surgical implants of the present disclosed include a film comprising a first therapeutic agent and a mesh comprising a second therapeutic agent. The surgical implant includes a film in direct contact with a mesh. The first therapeutic agent may be released at a first ra...
09/29/2011
20110236460Therapeutic Implant
Surgical implants of the present disclosed include a film comprising a first therapeutic agent and a mesh comprising a second therapeutic agent. The surgical implant includes a film in direct contact with a mesh. The first therapeutic agent may be released at a first ra...
09/29/2011
20110196042COMPOSITIONS AND METHODS FOR INFLUENCING SATIETY, LIPID METABOLISM, AND FAT UTILIZATION
The invention provides (1) genes differentially expressed in animals administered fatty acid amides that affect one or more of food intake, satiety, lipid metabolism, and fat utilization and (2) compositions and methods relating to the use of the genes to identify new c...
08/11/2011
20110196043METHODS AND COMPOSITIONS FOR ADMINISTRATION OF TRPV1 AGONISTS
Compositions are provided that contain a TRPV1 agonist, such as capsaicin, and a solvent system. Topical application of the composition results in rapid delivery of agonist to the dermis and epidermis. Method of using the compositions for reducing nociceptive nerve fibe...
08/11/2011
20110189270Differential Loading Of Drug-Eluting Medical Devices
A medical device includes a substrate having at least one surface. The surface has a central portion and a peripheral portion. At least one bioactive agent is disposed over at least a portion of the surface. The medical device having a concentration gradient of the at l...
08/04/2011
20110182972LOW-CONCENTRATION CAPSAICIN PATCH AND METHODS FOR TREATING NEUROPATHIC PAIN
Described here are patches and methods for treating neuropathic pain. In some variations, the neuropathic pain-relieving patch comprises capsaicin or a capsaicin analog, wherein the concentration of the capsaicin or capsaicin analog is less than 1% by weight, and a pene...
07/28/2011
20110184069METHODS AND COMPOSITIONS FOR ADMINISTRATION OF TRPV1 AGONISTS
Compositions are provided that contain a TRPV1 agonist, such as capsaicin, and a solvent system. Topical application of the composition results in rapid delivery of agonist to the dermis and epidermis. Method of using the compositions for reducing nociceptive nerve fibe...
07/28/2011
20110178151COMPOUNDS AND METHODS OF TREATING OBESITY
The present invention relates to novel fatty acid derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially as agents for the treatment of obesity and related disor...
07/21/2011
20110172305Endocannabinoids for Enhancing Growth and Development in Infants
The present invention relates to a method for promoting infant feeding, growth or development comprising administering to an infant a formula or a pharmaceutical composition comprising an endocannabinoid in an amount sufficient to promote feeding, growth or development....
07/14/2011
20110166196TREATMENT AND PROPHYLAXIS OF EPILEPSY AND FEBRILE SEIZURES
Provided are methods for treatment and prophylaxis of convulsive disorders and seizures, such as epilepsy and febrile seizures, by modulating TRPV1 channel activation....
07/07/2011
20110165198METHOD FOR REDUCING LIPID ABSORPTION BY AN ANIMAL
The invention provides methods for using fatty acid alkanolamides for reducing lipid absorption from the intestine of an animal. Reducing lipid absorption results in fewer lipids available for an animal to convert to body fat. Converting fewer lipids to body fat means t...
07/07/2011
20110135627PAIN RELIEF COMPOSITION, SYSTEM AND METHOD
A composition for the relief of pain includes comprising a transducer, a fibrinolytic, at least one of a pain relief agent or an anti-inflammatory agent. The pain relief agent can be capsaicin and the fibrinolytic can be bromelain. The composition can also include at le...
06/09/2011
20110118347TREATMENT Of RINGWORM
A compound of the formula CH3(CH2)n—RA—(CH2)m-(CH═CH)q—(CH2)p—X wherein RA=(a); q=0 or 1; m and p are independently selected integers of at least 1; n=0 or an in...
05/19/2011
20110086818METHODS, COMPOSITIONS, AND KITS FOR TREATING PAIN AND PRURITUS
The invention features methods, compositions, and kits for selective inhibition of pain-and itch sensing neurons (nociceptors and pruriceptors) by drug molecules of small molecule weight, while minimizing effects on non-pain-sensing neurons or other types of cells....
04/14/2011
20110077239GLYCINE RECEPTOR AGONISTS FOR THE TREATMENT OF PHANTOM PHENOMENA
A medicament for the treatment of the phantom phenomena of acute tinnitus and/or phantom pain, a method for the production of such a medicament, and a method for the treatment of such phantom phenomena...
03/31/2011
20110065627Transdermal delivery of medicaments with combinations of cetylated fatty fatty ester penetrant complexes
This invention describes a topical delivery mechanism that contains a mixture of cetylated fatty esters that act as transdermal carriers of desired therapeutic molecules. The proposed cetyl fatty ester penetrant-complex (Base CFEP-complex) contains specific cetyl fatty ...
03/17/2011
20110065801ENZYMATIC SYNTHESIS OF SPHINGOLIPIDS
The invention relates to the enzymatic synthesis of sphingolipids and compositions comprising sphingolipids from lysosphingolipids and carboxylic esters, and to cosmetic, dermatological or pharmaceutical formulations which comprise these sphingolipids or compositions....
03/17/2011
20110059177Cardioplegia Solution for Cardiac Surgery
The invention relates to improved cardioplegia solutions. The invention provides cardioplegia solutions and compositions that produce a readily reversible, rapid electrochemical arrest with minimal tissue ischaemia. The cardioplegia solutions and compositions are used f...
03/10/2011
20110045073METHODS AND COMPOSITIONS OF SPHINGOLIPID FOR PREVENTING AND TREATING MICROBIAL INFECTIONS
The present invention relates to controlled release composition for preventing and/or treating microbial infections in the oral cavity of a subject, said composition comprising a controlled delivery matrix which matrix has releasably associated therewith an amount of be...
02/24/2011
20110033503DRESSING COMPOSITIONS AND METHODS
Described is a spray-on hydrogel comprising water-soluble PEG polymers that cross-link in situ to form a hydrogel such that the cross-links are reversible. The hydrogel can be useful as a drug delivery composition, wound dressing or surgery adjuvant. Polyethylene glycol...
02/10/2011
20110033525Diterpene Glycosides as Natural Solubilizers
Several diterpene glycosides (e.g., rubusoside, rebaudioside, steviol monoside and stevioside) were discovered to enhance the solubility of a number of pharmaceutically and medicinally important compounds, including but not limited to, paclitaxel, camptothecin, curcumin...
02/10/2011
20110027326External Composition for Skin
An external composition for skin is provided, which gives good warmth without inducing irritation or pain and whose sustainability of warmth is good. The external composition for skin contains (A) an agent for giving warmth and (B) at least one member selected from the ...
02/03/2011
20110028382TREATMENT OF ORAL PHARYNGEAL DYSPHAGIA
The invention provides compounds for use in a method of treating oral pharyngeal dysphagia in an individual and related products. One embodiment of the invention comprises administering to an individual an effective amount of a vanilloid receptor 1 (VR-1) agonist or hig...
02/03/2011
20110014269CIVAMIDE PATCH FOR LOCALIZED POST-INCISIONAL NEUROPATHIC PAIN
A dermal method of treating chronic post-operative pain with a TRPV-1 receptor modulator. More specifically, a method for treating localized post-incisional neuropathic pain by administering a civamide-containing patch....
01/20/2011
20100330187CAPSICUM FOOD ADDITIVE AND USES THEREOF
The invention relates to a food additive that includes, relative to the total weight thereof: about 3.5 wt % of capsicum oleoresin containing 6 wt % of a capsaicine and dihydrocapsaicine mixture; about 5.5 wt % of cinnamaldehyde; about 9.5 wt % of eugenol; the ba...
12/30/2010
20100322961Intranasal Drug Delivery System
The present invention provides an intranasal drug delivery system containing capsaicin, dihydrocapsaicin, nordihydrocapsaicin, homodihydrocapsaicin, and homocapsaicin in the form of oleoresin capsicum used as a carrier to quickly and effectively deliver a drug....
12/23/2010
20100316678COMBINATION METHODS AND COMPOSITIONS FOR TREATMENT OF NEUROPATHIC PAIN
The present invention relates generally to the field of pain management, and in particular, the management of neuropathic pain. The present invention further provides methods and compositions that treat, alleviate, prevent, diminish or otherwise ameliorate the symptoms ...
12/16/2010
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