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Patent No. 5871518

Smoking Cessation Lighter and Method

A lighter for tobacco products suppresses the urge to smoke by operant conditioning.

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Class 514/622 - C-O- group in R


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the carboxylic acid residue (R) contains
No. of applications: 224
Last issue date: 05/03/2012


1            
Application No.Application TitleIssue Date
20120108666Treatment of Cell Proliferative Disorders
The invention relates to compounds and their use in treating cell proliferative disorders, more specifically Syk tyrosine kinase-mediated disorders....
05/03/2012
20120108592PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF SALICYLANILIDES FOR TREATMENT OF HEPATITIS VIRUSES
A new class of salicylanilides is described. These compounds show strong activity against hepatitis viruses....
05/03/2012
20120046293RENIN INHIBITORS
The present invention relates to renin inhibitor compounds having the structure

and their use in treating cardiovascular events and renal insufficiency....

02/23/2012
20120022039NOVEL SUBSTITUTED INDANES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS DRUGS
The invention relates to substituted indanes and derivatives thereof, to physiologically acceptable salts and physiologically functional derivatives thereof, to the production thereof, to drugs containing at least one substituted indane according to the invention or der...
01/26/2012
20120015978THERAPEUTIC AGENTS FOR OCULAR HYPERTENSION
This invention provides well defined 6-alkyl or hydroxyalkyl-1-naphthamide or quinoline compounds for treating glaucoma or ocular hypertension....
01/19/2012
20120010178METHODS AND COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISORDERS
Methods, compounds and compositions for promoting motor neuron survival and the treatment of a neurodegenerative disorders such as Spinal Muscular Atrophy (SMA) are described herein....
01/12/2012
20110319487POLYMERIC DELIVERY SYSTEM FOR A NONVISCOUS PROSTAGLANDIN-BASED SOLUTION WITHOUT PRESERVATIVES
This invention concerns an ophthalmic solution including:
    • at least one prostaglandin;
12/29/2011
20110311623COMPOSITION FOR MANUFACTURING ORALLY DISINTEGRATING DOSAGE FORM TO PROTECT COATING LAYER OF ACTIVE SUBSTANCE
The present invention relates to a composition for manufacturing an orally disintegrating dosage form that is used to prevent a coating layer of an active substance which is formed in a predetermined size in order to mask a bitter taste or an unpleasant taste. A predete...
12/22/2011
20110313038CATIONIC OIL-IN-WATER EMULSIONS CONTAINING PROSTAGLANDINS AND USES THEREOF
A colloidal cationic oil-in-water emulsion includes: —a prostaglandin, —an oil having a iodine value ≦2, —one or more surfactants including at least one quaternary ammonium compound, —water, wherein the prostaglandin/total sum of surfactants mass ratio is incl...
12/22/2011
20110301179NAPHTHAMIDES AS ANTICANCER AGENTS
A compound (particularly useful for inhibiting cancer) according to formula I:

    • or a phar...
12/08/2011
20110294880PHARMACEUTICAL COMPOSITION CONTAINING PROSTAGLANDIN
An object of the present invention is to provide a stable aqueous pharmaceutical composition which suppresses degradation of prostaglandin Fin a preparation containing prostaglandin F. The object was attained by formulating a prostaglandin F...
12/01/2011
20110293549COMPOSITION, METHOD AND KIT FOR ENHANCING HAIR
Compositions for application and methods of application of a composition to modify hair. In one embodiment, a composition includes a compound (molecule) represented by:

12/01/2011
20110294893NON-ACIDIC CYCLOPENTANE HEPTANOIC ACID, 2-CYCLOALKYL OR ARYLALKYL DERIVATIVES AS THERAPEUTIC AGENTS
The present invention provides cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compounds, which may be substituted in the 1-position with amino, amido, ether or ester groups, e.g., a 1-OH cyclopentane heptanoic acid, 2-(cycloalkyl or arylalkyl) compound. The cycl...
12/01/2011
20110288179BIMATOPROST CRYSTALLINE FORM I
The invention provides a novel polymorphic form I of crystalline bimatoprost, method for preparation thereof and new crystalline intermediates in the preparation. This form I of crystalline bimatoprost is used in purification of crude bimatoprost and in storage of bimat...
11/24/2011
20110275577METHODS OF TREATING DERMATOLOGIC, GYNECOLOGIC, AND GENITAL DISORDERS WITH CAFFEIC ACID ANALOGS
The present invention relates to caffeic acid analog compounds and methods which may be useful for regeneration, cellular programming, and the treatment of dermatologic, gynecologic, and genital diseases such as inflammatory dermatologic conditions, dysplasia, neoplasia...
11/10/2011
20110275603NOVEL IMMUNOMODULATOR AND ANTI-INFLAMMATORY COMPOUNDS
The present invention provides dihydroorotate dehydrogenase inhibitors, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of diseases or disorders wherein the inhibition of Dihydroorotate dehy...
11/10/2011
20110269834COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES
Described herein are compounds and compositions, and methods for using the compounds and compositions, for treating respiratory diseases and illness, such as severe acute respiratory syndrome (SARS)....
11/03/2011
20110250285OIL-IN-OIL EMULSIFIED POLYMERIC IMPLANTS CONTAINING A HYPOTENSIVE LIPID AND RELATED METHODS
Biocompatible intraocular implants, such as microparticles, include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be assoc...
10/13/2011
20110237551Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions
The invention relates to the use of para-coumaric acid or para-hydroxycinnamic acid derivatives in cosmetic or dermatological compositions, specifically to the use of at least one compound derived from para-coumaric acid having a general formula (I) below:

09/29/2011

20110230437ORGANIC COMPOUNDS
A composition comprising a compound of formula I CH3CH(OH)CC═O)NR1R2 (I) where R1 and R2 are each independently hydrogen; or C1-6 alkyl, C2-6 alkenyl or C3-6 cycloalkyl, each of wh...
09/22/2011
20110224304BIPHENYLACETAMIDE DERIVATIVE
The present invention provides a compound of formula (I) or a salt thereof, wherein R1, R2 and R3 are independently selected from the group consisting of hydrogen atom, fluorine atom, chlorine atom, bromine atom, C1-6 alkyl, C...
09/15/2011
20110224260CATECHOL-BASED DERIVATIVES FOR TREATING OR PREVENTING DIABETICS
The present invention provides a catechol-based derivative and a pharmaceutical acceptable salt therefrom and a solvate therefrom. A pharmaceutical composition for preventing or treating diabetes and ischemia, comprising a catechol-based derivative of formula (I) and at...
09/15/2011
20110224294CINAMIC COMPOUNDS AND DERIVATIVES THEREFROM FOR THE INHIBITION OF HISTONE DEACETYLASE
The invention relates to a compound represented by the following formula (I):

and pharmaceutically acceptable salts, stereoisomers, enantiomers, prodrugs and solvates thereof. The compounds are useful as an a...

09/15/2011
20110212994Small Molecule Choline Kinase Inhibitors, Screening Assays, and Methods for Safe and Effective Treatment of Neoplastic Disorders
Small molecule choline kinase inhibitors, pharmaceutical compositions thereof, and screening methods for identifying and evaluating choline kinase inhibitors are provided. Safe and effective methods for treating subjects suffering from a disorder or disease characterize...
09/01/2011
20110197318Seed Treatment Agent and Method for Protecting Plant
PROBLEM Provided is a seed treatment agent having excellent control effect on plant diseases and a method for protecting a plant from plant diseases.

SOLUTION A seed treatment agent comprising, as an active ingredient, an α-methoxyphenylac...

08/11/2011
20110182966INTRACAMERAL SUSTAINED RELEASE THERAPEUTIC AGENT IMPLANTS
Described herein are intracameral implants including at least one therapeutic agent for treatment of at least one ocular condition. The implants described herein are not anchored to the ocular tissue, but rather are held in place by currents and gravity present in the a...
07/28/2011
20110178042Hydroxamic Acid Derivatives Useful as Antibacterial Agents
The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, thereof, wherein: G is a group of formula (II); and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates, thereof, wherein A, B. L1-L4 ...
07/21/2011
20110172208NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, USE OF THE CATECHOL DERIVATIVE, AND USE OF THE PHARMACEUTICAL COMPOSITION
The present invention provides compounds represented by general formula (I):

or pharmaceutical acceptable salts thereof, wherein R1 and R2 are each hydrogen, lower acyl, lower alkoxycarb...

07/14/2011
20110172239Compounds, Compositions and Methods for the Treatment of Amyloid Diseases and Synucleinopathies such as Alzheimer's Disease, Type 2 Diabetes and Parkinson's Disease
Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially Aβ amyloidosis, such as observed ...
07/14/2011
20110172177COMBINATION, KIT AND METHOD OF REDUCING INTRAOCULAR PRESSURE
The present invention is directed to a combination or a kit comprising a prostaglandin analog and an adenosine receptor A1 agonist and to a method of reducing intraocular pressure (IOP) in a subject using such combination or kit. The invention is particularly...
07/14/2011
20110172311Compounds For Treating Human Papillomavirus
Methods and compositions for treating human papillomavirus infections are described....
07/14/2011
20110152226Development of New Selective Estrogen Receptor Modulators
The present disclosure concerns a new class of selective estrogen receptor modulators (SERMs). The disclosure also includes the identification of a previously unknown membrane associated estrogen receptor. Methods for making and using the disclosed SERMs are disclosed, ...
06/23/2011
201101523767-[3,5-DIHYDROXY-2- (3-HYDROXY-5-PHENYL-PENT-1-ENYL)- CYCLOPENTYL]-N-ETHYL-HEPT-5-ENAMIDE (BIMATOPROST) IN CRYSTALLINE FORM II, METHODS FOR PREPARATION, AND METHODS FOR USE THEREOF
The present invention provides a new crystalline form of bimatoprost, designated as crystalline form II. This new crystalline form is the most stable form known to date of bimatoprost. Moreover, it has been found that bimatoprost crystalline form II is readily prepared ...
06/23/2011
20110152291NOVEL AROMATIC COMPOUNDS AND THEIR USE IN MEDICAL APPLICATIONS
Pharmaceutical compositions comprising at least one compound of the formulas (Ia) or (Ib) and a pharmaceutically acceptable carrier wherein the symbols have the following meaning —X- is e.g. and Y being e.g. or the pharmaceutically acceptable salts can be applied to m...
06/23/2011
20110144124Compounds and Compositions for Use as Modulators of Tau Aggregation and Alleviation of Tauopathies
This invention relates to the use of bis- and tris-dihydroxyaryl compounds as well as sulfonamides, heteroaryls, tricycloalkyl and their analogs and pharmaceutically acceptable salts, for modulating tau aggregation and alleviating tauopathies, such as Alzheimer's diseas...
06/16/2011
20110144043Stat modulators
The present invention is directed to methods, kits and compositions for modulating the activity of Stat molecules (e.g., Stat1, Stat3 and Stat5). The compounds of the invention are useful for treating and/or preventing disorders characterized by Stat dysregulation, such...
06/16/2011
20110136807Bicyclic compositions and methods for modulating a kinase cascade
The invention relates to compounds and methods for modulating one or more components of a kinase cascade....
06/09/2011
20110130448FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM
The present invention relates to a compound of the formula:


R-AR—O—Y—R′

06/02/2011
20110124737ENHANCED BIMATOPROST OPHTHALMIC SOLUTION
A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein.

A me...

05/26/2011
20110124736COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH
Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I

    ...
05/26/2011
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