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| Application No. | Application Title | Issue Date |
| 20120046365 | Method and Composition for Administering an NMDA Receptor Antagonist to a Subject The invention provides methods and compositions for administering an NMDA receptor antagonist (e.g., memantine) to a subject.... | 02/23/2012 |
| 20120034313 | Microbiocide/Sulfide Control Blends A chemical blend that simultaneously kills bacteria and suppresses the production of hydrogen sulfide (H2S) includes both a first chemical, which may be a glutaraldehyde, a tetrakishydroxymethyl phosphonium sulfate (THPS), a quaternary amine compound, a thioc... | 02/09/2012 |
| 20120015901 | METHODS AND PREPARATIONS FOR PROTECTING CRITICALLY ILL PATIENTS The present invention relates to a method of treating a life threatening condition in a critically ill human patient with a non-infectuous disorder, wherein the critically ill patient is a patient receiving enteral or parenteral nutrition, the method comprising the step... | 01/19/2012 |
| 20110294890 | Neramexane for the treatment or prevention of inner ear disorders The present invention relates to a method of treatment or prevention of an inner ear disorder in a female comprising administering a therapeutically effective amount of neramexane or a pharmaceutically acceptable salt thereof to a female.... | 12/01/2011 |
| 20110281809 | METHODS AND COMPOSITIONS FOR RAPID TREATMENT OF OTITIS EXTERNA Methods for treating and preventing otitis externa with a course of treatment consisting of as little as a single dose are provided. The methods are practiced by topical administration of compositions having a lipid carrier, such as liposomes and non-vesicular lipids, t... | 11/17/2011 |
| 20110251283 | 1-AMINO-ALKYLCYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF MAST CELL MEDIATED DISEASES The present invention relates to the treatment of an individual afflicted with mast cell mediated diseases comprising administering to the individual an effective amount of a 1-amino-alkylcyclohexane derivative.... | 10/13/2011 |
| 20110236439 | Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane The present invention relates to an immediate release solid oral dosage form containing 1-aminocyclohexanes, preferably memantine or neramexane, and optionally a pharmaceutically acceptable coating, wherein the active ingredient exhibits dose proportionality and is rele... | 09/29/2011 |
| 20110237563 | FAST DISSOLVING DRUG DELIVERY SYSTEMS The present invention related to the administration of bioactive agents via oral fast dispersing/dissolving drug delivery systems for treating illnesses of patient with critical buccal condition, leading to difficulties in swallowing oral medicine forms and thus difficu... | 09/29/2011 |
| 20110207793 | 1-AMINOCYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF SLEEP DISORDERS. The present invention relates to the treatment of an individual afflicted with sleep disorders associated with tinnitus and/or neurological diseases comprising administering to the individual an effective amount of a 1-amino-alkylcyclohexane derivative.... | 08/25/2011 |
| 20110178179 | 1-AMINO-ALKYLCYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF COGNITIVE IMPAIRMENT IN TINNITUS The present invention relates to the treatment of an individual afflicted with cognitive impairment associated with tinnitus comprising administering to the individual an effective amount of a 1-amino-alkylcyclohexane derivative.... | 07/21/2011 |
| 20110118307 | Compositions and methods for the treatment of infectious diseases Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the treatment of infectious diseases are provided. In one embodiment, these methods... | 05/19/2011 |
| 20110092600 | PHARMACEUTICAL COMPOSITIONS COMPRISING AMINOCYCLOHEXANE DERIVATIVES The present invention relates to pharmaceutical compositions comprising 1-aminocyclohexane derivatives and a cyclodextrin, which compositions exhibit advantageous safety, convenience, and dosing characteristics. The compositions of the instant invention find particular ... | 04/21/2011 |
| 20110086916 | INTERVAL THERAPY FOR THE TREATMENT OF TINNITUS The present invention relates to interval and/or maintenance therapy employing 1-amino-alkylcyclohexane derivatives (e.g., neramexane or a pharmaceutically acceptable salt thereof) for the treatment of an individual afflicted with tinnitus.... | 04/14/2011 |
| 20110077304 | 1-AMINOCYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF COCHLEAR TINNITUS. The present invention relates to the treatment of an individual afflicted with cochlear tinnitus comprising administering to the individual an effective amount of a 1-amino-alkylcyclohexane derivative.... | 03/31/2011 |
| 20110070171 | 1-tert-Butylcyclohexanecarboxamide and uses thereof as cooling compounds Described is a new cooling agent represented by Formula I and compositions with known coolers having cooling properties and the application of Formula I in foodstuffs and chewing gum: wherein X, Y is independ... | 03/24/2011 |
| 20110059122 | Inhibition of the Survival of Oral Cavity Cancer by Cyclohexenone Compounds from Antrodia Camphorata The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of Antrodia camphorata, which... | 03/10/2011 |
| 20110059123 | Inhibition of the Survival of Colorectal Cancer by Cyclohexenone Compounds from Antrodia Camphorata The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of Antrodia camphorata, which... | 03/10/2011 |
| 20110052732 | MINERAL ABSORPTION ACCELERATOR AND IRON DEFICIENCY ANEMIA IMPROVER OF FOOD COMPOSITION A mineral absorption accelerator, and an anemia improving agent, food and drink or food and drink material containing the mineral absorption accelerator are provided, the mineral absorption accelerator including: an α-glucosidase inhibitory component.... | 03/03/2011 |
| 20100298440 | 1-AMINOCYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF HEARING LOSS The present invention relates to the treatment of an individual diagnosed with hearing loss comprising administering to the individual an effective amount of a 1-amino-alkylcyclohexane derivative.... | 11/25/2010 |
| 20100298442 | 1-Amino-alkyl-cyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists Certain 1-aminoalkylcyclohexanes are systematically-active 5HT3 and nicotinic receptor antagonists and are useful in the inhibition of progression of or alleviation of conditions resulting from disturbances of serotoninergic or nicotinergic transmission giving them a wi... | 11/25/2010 |
| 20100298441 | TITRATION PACKAGE FOR NERAMEXANE AND ITS USE IN THE TREATMENT OF AN INNER EAR DISORDER The present invention relates to a titration scheme for the administration of a 1-amino-alkylcyclohexane derivative which allows for quick attainment of an effective dose of a 1-amino-alkylcyclohexane derivative while minimizing side effects. The present invention furth... | 11/25/2010 |
| 20100234358 | NERAMEXANE FOR THE TREATMENT OF NYSTAGMUS The present invention relates to the treatment of an individual diagnosed with nystagmus comprising administering to the individual an effective amount of a 1-aminoalkylcyclohexane derivative, for example neramexane or a pharmaceutically acceptable salt thereof, such as... | 09/16/2010 |
| 20100197792 | 1-Amino-Alkylcyclohexane derivatives for the treatment of inflammatory skin diseases The present invention relates to the treatment of an individual afflicted with inflammatory skin diseases comprising administering to the individual an effective amount of a 1-amino-alkylcyclohexane derivative.... | 08/05/2010 |
| 20100190751 | NOVEL COMBINATION OF NERAMEXANE FOR TREATMENT OF NERORDEGENERATIE DISORDERS The present invention relates to combinations comprising neramexane and a Glutamate Release Inhibitor (GRI) and the use of such combinations in the treatment of neurodegenerative disorders.... | 07/29/2010 |
| 20100075925 | Hyperthermic Technologies And Therapeutic Uses Thereof The present invention provides nanoscale and microscale compositions useful for a variety of purposes, including the diagnosis and treatment of diseases. In one embodiment, the present invention provides a disease treatment system comprising a thermal induction agent an... | 03/25/2010 |
| 20100076073 | Combination of an NMDA receptor antagonist and a selective serotonin reuptake inhibitor for the treatment of depression and other mood disorders The present invention provides a method for the treatment of depression, including treatment-resistant depression, and other mood disorders using a combination of an NMDA receptor antagonist and a SSRI that is citalopram or escitalopram. It has unexpectedly been shown t... | 03/25/2010 |
| 20100035995 | Compositions comprising Cyclohexylamines and Aminoadamantanes The invention is directed to formulations of pharmaceutical compounds, such as the Cyclohexylamines and Aminoadamantanes which have antimicrobial properties. In particular, it is directed to aqueous based formulations with reduced amounts of preservatives which allow sa... | 02/11/2010 |
| 20090306196 | IMINE BASED LIQUID CRYSTALS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS The present invention relates to a delivery system based on a film of an imine forming liquid crystalline phase, mixed with at least with one biologically active substance, to which a constant or variable electric field can be applied. The delivery system can be used as... | 12/10/2009 |
| 20090298745 | Treatment of Diabetes with Glycogen Phosphorylase Inhibitors The invention provides a method of treatment of diabetes, particularly type II diabetes, or a diabetes related condition, comprising night time dosing of an inhibitor of glycogen phosphorylase, optionally in combination another anti-diabetic therapy.... | 12/03/2009 |
| 20090280147 | Compositions comprising dye-loaded particles According to the invention, a cosmetic composition is provided comprising: (a) amorphous particles, each amorphous particle comprising a homogeneous distribution of one or more dyes encapsulated by an amorphous, siliceous encapsulating agen... | 11/12/2009 |
| 20090275597 | METHODS OF TREATING CNS DISORDERS The present invention relates to methods of treating various CNS disorders, e.g., mania, bipolar disorder and schizophrenia, by administering NMDA receptor antagonists, alone or in combination with dopamine receptor antagonists.... | 11/05/2009 |
| 20090233935 | Methods for Fabrication of Antimicrobial Surfaces A method for rendering a carboxyl-containing polymer surface resistant to microbial growth, the method comprising: (i) reacting the carboxyl-containing polymer surface with a metal borohydride in a solvent system comprising a water-soluble alcohol having one to three hy... | 09/17/2009 |
| 20090197963 | Method and compositions for suppressing appetite or treating obesity The present invention provides a method for reducing the appetite in a mammal by contacting the mammal with an amount of a noxious smelling agent effective in reducing appetite or by contacting the mammal with an agent effective in inhibiting the effect of another agent... | 08/06/2009 |
| 20090169495 | Merocyanine Derivatives Disclosed are merocyanine derivatives of formula (1), wherein R1 and R2 independently from each other are branched C4-C22alkyl; or branched C4-C12 alkenyl; R3 and R4 independently fr... | 07/02/2009 |
| 20090092642 | Skin and/or Hair Products, Containing Compounds With an Isoprenoid Structure A composition of matter that is suitable for use on skin or hair. The composition comprises one or more compounds of formula wherein Rx, Ry, R3 and R5 are as defined in the specification... | 04/09/2009 |
| 20090081259 | 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect The present invention relates to the treatment of individuals diagnosed with multiple sclerosis, emotional lability or pseudobulbar affect comprising administering to said individual an effective amount of a 1-aminocyclohexane derivative, namely memantine or neramexane.... | 03/26/2009 |
| 20090022826 | Multi-step method of pain and/or inflammation treatment The present invention provides multi-step methods for treating pain and/or inflammation. In a preferred embodiment, the method comprises administering to a patient in need of relief of pain and/or inflammation the following three components... | 01/22/2009 |
| 20090012120 | Synthesis of N-heterocycles, beta-amino acids, and allyl amines via aza-payne mediated reaction of ylides and hydroxy aziridines An ylide-based aza-Payne rearrangement of 2,3-aziridin-1-ols leads to an efficient process for the preparation of pyrrolidines. The aza-Payne rearrangement under the basic reaction conditions favors the formation of epoxy amines. Subsequent nucleophilic attack of... | 01/08/2009 |
| 20080260716 | Method and Composition for High Level Disinfection Employing Quaternary Ammonium Compounds Methods and compositions for high level disinfection (as herein defined) of a surface. Methods include treating the surface with a composition including a quaternary ammonium compound in a concentration which exceeds 1% w/w and the temperature of treatment is in the ran... | 10/23/2008 |
| 20080241245 | Drug delivery device for providing local analgesia, local anesthesia or nerve blockage The invention relates to a drug delivery device for providing local analgesia, local anesthesia or nerve blockade at a site in a human or animal in need thereof, the device comprising a fibrillar collagen matrix; and at least one drug substance selected from the group c... | 10/02/2008 |
