System for magnetically attaching templeless eyewear to a person
A system of eyewear that eliminates the need for hinges on the frames of the eyewear.
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| Application No. | Application Title | Issue Date |
| 20120107400 | SUSTAINED RELEASE COMPOSITION OF THERAPUTIC AGENT A pH dependent drug delivery system comprising a pH sensitive graft copolymer, a therapeutically active agent and other pharmaceutically acceptable ingredients. More specifically, a composition which is capable of suppressing the drug release in the acidic pH prevalent ... | 05/03/2012 |
| 20120108551 | OPHTHALMIC COMPOSITIONS The present invention relates to compositions that may alleviate symptoms of ocular stress, as well as methods of their production, use, and storage compositions. The compositions comprise at least one ocular epithelial cell associating group and at least one hydrophili... | 05/03/2012 |
| 20120070492 | RHEIN OR DIACEREIN COMPOSITIONS The invention relates to pharmaceutical compositions comprising rhein or diacerein or salts or esters or prodrugs thereof, optionally with one or more pharmaceutically acceptable excipients. The invention also relates to the methods for preparing such compositions.... | 03/22/2012 |
| 20120071550 | Synergistic combinations of cartonoids and polyphenols The present invention provides a therapeutic composition comprising one or more polyphenols and one or more carotenoids selected from the group consisting of lutein, lycopene and beta-carotene. The invention also provides methods for inhibiting or reducing the productio... | 03/22/2012 |
| 20120046307 | ALLOSTERIC PROTEIN KINASE MODULATORS The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions compris... | 02/23/2012 |
| 20120035196 | CARBOXYLIC ACID COMPOUND [Problem] The present invention has an object to provide a compound having a GPR40 agonistic activity, which is useful as a pharmaceutical composition, an insulin secretion promoter, or an agent for preventing/treating diabetes. 02/09/2012 | |
| 20120015992 | Napthalene-Based Inhibitors of Anti-Apoptotic Proteins Methods of using apogossypol and its derivatives for treating inflammation is disclosed. Also, there is described a group of compounds having structure A, or a pharmaceutically acceptable salt, hydrate, N-oxide, or solvate thereof are provided: 01/19/2012 | |
| 20120016031 | BIPHENYL COMPOUND SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS Biphenyl compounds having the formula (I): are useful for preventing/treating pathologies linked to a deficiency of the activation of the RAR gamma receptor, e.g., for treating a pathology linked to a cell di... | 01/19/2012 |
| 20120015960 | CHEMICAL INHIBITOR OF P53-SNAIL BINDING AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER DISEASE CONTAINING SAME AS ITS ACTIVE INGREDIENT Provided are compounds for inhibiting Snail-p53 binding and therapeutic agents for cancer including the compounds as an effective component. The Snail-p53 binding inhibitors induce expression of p53 in K-Ras mutant cell lines, thereby enabling effective treatment or pre... | 01/19/2012 |
| 20120009243 | LIPOSOMES FOR DRUG DELIVERY AND METHODS FOR PREPARATION THEREOF The present invention provides liposomes that are useful for delivery of bioactive agents such as therapeutics. Among others, the liposomes of the invention are capable of delivering their payload at sites of increased secretory phospholipase A2 (sPLA2) activity, becaus... | 01/12/2012 |
| 20120004307 | ORAL TREATMENT OF DIGITAL ISCHEMIC LESIONS Provided are methods of orally treating ischemic diseases and conditions, such as digital ulcers, associated with or caused by the ischemic diseases.... | 01/05/2012 |
| 20120003181 | Novel Retinoid Inducible Factor and Uses Thereof The present invention describes a novel retinoid-responsive nucleic acid, and a novel protein. Further, the invention describes the use of such a nucleic acid or protein in various diseases, and for the treatment, the diagnosis and prognosis of various diseases, and als... | 01/05/2012 |
| 20120003156 | METHODS FOR TREATING NEOPLASIA BY INHIBITING LACTATE DEHYDROGENASE AND/OR NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE The invention provides compositions for the diagnosis or treatment of neoplasias, including lymphomas, leukemias, brain cancers (e. glioblastomas, medulloblastomas), breast cancer, colon cancer, and pancreatic cancer, and methods of use therefor.... | 01/05/2012 |
| 20110318321 | CONTROLLED RELEASE PHARMACEUTICAL OR FOOD FORMULATION AND PROCESS FOR ITS PREPARATION The present invention relates to a controlled release pharmaceutical or food formulation comprising at least one active pharmaceutical or food ingredient dispersed in a mixture of a glycogen with a polysaccharide, and the process for its preparation. The invention also ... | 12/29/2011 |
| 20110319399 | EXTERNAL PREPARATION CONTAINING ANALGESIC/ANTI-INFLAMMATORY AGENT An external preparation containing the following components (A) and (B):
| 12/29/2011 |
| 20110319491 | ANHYDROUS DEPIGMENTING COMPOSITIONS COMPRISING, WITHIN THE FATTY PHASE THEREOF, A SOLUBILIZED PHENOLIC COMPOUND AND A RETINOID Novel anhydrous dermatological depigmenting compositions, especially for topical application, contain, within the fatty phase thereof, as pharmaceutical active agents, a dissolved phenolic compound and a retinoid.... | 12/29/2011 |
| 20110318396 | DERMATOLOGICAL/COSMETIC COMPOSITIONS COMPRISING A RETINOID AND BENZOYL PEROXIDE Dermatological/cosmetic compositions contain, in a physiologically acceptable medium, at least one retinoid, dispersed benzoyl peroxide and a gelling system comprising at least two categories of compounds.... | 12/29/2011 |
| 20110313032 | COMPETITIVE INHIBITORS OF TYPE II DEHYDROQUINASE ENZYME The present invention is directed to a compound of formula (I), its diastereoisomers, its enantiomers or its pharmaceutically acceptable salts or solvates, formula (I), to procedures of obtaining the same, to intermediates thereof, and use as competitive inhibitors of t... | 12/22/2011 |
| 20110311594 | CONTROLLED RELEASE COMPOSITIONS WITH REDUCED FOOD EFFECT The present invention provides a controlled release pharmaceutical composition which exhibits reduced food effect.... | 12/22/2011 |
| 20110312984 | STAT3 INHIBITORS Small molecule inhibitors of Stat3 and their derivatives are disclosed. Also described are methods to inhibit cell growth by use of Stat3 inhibitors, and the use of Stat3 inhibitors for the prevention and/or treatment of cancer. Further, inhibitors of Stat3 that also do... | 12/22/2011 |
| 20110305747 | COMBINATION OF DAPSONE WITH OTHER ANTI-ACNE AGENTS A composition suitable for topical application that contains at least two active ingredients, one of these being dapsone and one selected from the group consisting of adapalene, tazarotene and treinion for the effective treatment of acne and other dermatological conditi... | 12/15/2011 |
| 20110305676 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplan... | 12/15/2011 |
| 20110301131 | Drug Delivery Implants and Processes for Their Preparation The invention discloses an implant suitable for delivery of at least one drug, the implant comprising a fibrillar collagen matrix having, as measured in Example 1, a viscosity of greater than 100 mPas, optionally greater than 103 mPas, further optionally greater than 10... | 12/08/2011 |
| 20110294815 | PROSTACYCLIN ANALOGS This invention relates to novel prostacyclin analogs and pharmaceutically acceptable salts thereof. More specifically, the invention relates to novel prostacyclin analogs that are derivatives of treprostinil. This invention also provides compositions comprising a compou... | 12/01/2011 |
| 20110288022 | TREATMENT OF DEPRESSIVE DISORDERS The invention provides for the use of carbonic anhydrase activators; protein kinase C activators and FGF-18 to treat depressive disorders. The invention also relates to improved animal models and methods for screening and identifying compounds the treatment of depressiv... | 11/24/2011 |
| 20110288146 | DIRECTLY COMPRESSIBLE GRANULAR MICROCRYSTALLINE CELLULOSE BASED, EXCIPIENT, MANUFACTURING PROCESS AND USE THEREOF An improved excipient comprising substantially homogeneous particles of a compressible, high functionality granular microcrystalline cellulose based excipient is provided. The improved excipient comprises microcrystalline cellulose and a binder, and optionally a disinte... | 11/24/2011 |
| 20110287091 | CHRONOTHERAPEUTIC PHARMACEUTICAL COMPOSITION The present invention relates to chronotherapeutic pharmaceutical compositions and a method of preparing the same. The composition comprises of at least one active ingredient, a pH independent agent and a hydrophilic agent. The active ingredient in the composition is co... | 11/24/2011 |
| 20110288066 | PHENOXY ACETIC ACID DERIVATIVES The present invention provides phenoxyacetic acid derivatives of Formula (I) for the treatment of CRTH2 related disorders and disease selected from asthma, atopic dermatitis and inflammatory dermatoses.... | 11/24/2011 |
| 20110281948 | COSMETIC AND PHARMACEUTICAL FORMULATIONS OF CALIXARENE MOLECULES The invention relates to the use of calixarenes for preventing or limiting the transfer of an actinide in the body from a site of skin contamination.... | 11/17/2011 |
| 20110281944 | METHOD OF A RHEIN COMPOUND FOR INHIBITING PANCREATIC ISLET BETA-CELL DYSFUNCTION AND PREVENTING OR TREATING A PANCREATIC ISLET BETA-CELL DYSFUNCTION RELATED DISORDER This invention provides a method for inhibiting pancreatic islet β-cell dysfunction, comprising administering to a subject in need thereof an inhibitory effective amount of a rhein compound having the general formula (I) or a pharmaceutically acceptable salt thereof, | 11/17/2011 |
| 20110274724 | DERMATOLOGICAL/COSMETIC GELS COMPRISING AT LEAST ONE RETINOID AND/OR RETINOID SALT AND BENZOYL PEROXIDE Dermatological/cosmetic gel compositions suited for preventing or treating cell differentiation and/or proliferation and/or keratinization disorders, including preventing or treating common acne, comprise (i) at least one retinoid, (ii) dispersed benzoyl peroxide and (i... | 11/10/2011 |
| 20110275658 | OPIOID-CONTAINING ORAL PHARMACEUTICAL COMPOSITIONS AND METHODS The present invention provides sustained-release oral pharmaceutical compositions and methods of use. The sustained-release oral pharmaceutical compositions include an opioid (including salts thereof) and a salt of a non-steroidal anti-inflammatory drug (NSAID).... | 11/10/2011 |
| 20110275691 | METHODS OF TREATING HEADACHES USING 5-HT AGONISTS IN COMBINATION WITH LONG-ACTING NSAIDS The invention is directed to methods and compositions that can be used in the treatment of headaches. In particular, methods and compositions are described involving the combination of a long-acting NSAID and a 5-HT1B/1D agonist.... | 11/10/2011 |
| 20110275581 | NUCLEAR EXPORT INHIBITORS OF TOPOISOMERASE II ALPHA A method of treating cancer in a subject comprising the step of administering to the subject in need thereof an effective amount of a combination of a compound that binds a nuclear export signal (NES inhibitor) on topoisomerase IIα and a topoisomerase inhibitor. Twenty... | 11/10/2011 |
| 20110268808 | DUAL-RELEASE PHARMACEUTICAL SUSPENSION Orally deliverable dual-release pharmaceutical suspensions, having a first portion comprising an immediate release form of the active in the solution form or granules or suspended form in the vehicle/medium preferably in the solution form and a second portion comprising... | 11/03/2011 |
| 20110269723 | SPILL RESISTANT FORMULATIONS CONTAINING CLAYS The invention relates to novel spill resistant formulations comprising either a weak base or a weak acid as the pharmaceutical ingredient, a liquid base, a clay and a water soluble cellulose ether. The clay and cellulose ether allow for a broader pH range into which the... | 11/03/2011 |
| 20110263693 | CELASTROL, GEDUNIN, AND DERIVATIVES THEREOF AS HSP90 INHIBITORS Based on the discovery that celastrol and gedunin are Hsp90 inhibitors, the present invention provides novel inhibitors of Hsp90. and pharmaceutically acceptable salts, derivatives, and compositions thereof. The invention provides two classes of compounds. One class inc... | 10/27/2011 |
| 20110263539 | SHIP 1 MODULATOR COMPOUNDS The present invention provides the use of pelorol analogs of Formula, (I) and pharmaceutical compositions thereof as modulators of SHIP 1 activity. A compound or a pharmaceutical composition of the present invention may be used for the treatment or prophylaxis of an inf... | 10/27/2011 |
| 20110257269 | PREVENTIVE AND/OR THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASES The present invention relates to a preventive and/or a therapeutic agent for inflammatory bowel diseases containing a fermentation product of a propionic acid bacterium as an active ingredient.... | 10/20/2011 |
| 20110257134 | CO-CRYSTALS OF TRAMADOL AND NSAIDs The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same, their uses in pharmaceutical formulations, and for the treatment of various disorders, including pain.... | 10/20/2011 |