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| Application No. | Application Title | Issue Date |
| 20120128724 | SYSTEMS AND METHODS FOR TREATING HUMAN INFLAMMATORY AND PROLIFERATIVE DISEASES AND WOUNDS, WITH FATTY ACID METABOLISM INHIBITORS AND/OR GLYCOLYTIC INHIBITORS Systems and methods for treating inflammatory and proliferative diseases, and wounds, using as a pharmacon a fatty acid metabolism inhibitor, a glycolytic inhibitor, and/or an agent able to alter cellular production of reactive oxygen, or combination thereof, optionally... | 05/24/2012 |
| 20120108664 | TRANSDERMAL DELIVERY OF BENEFICIAL SUBSTANCES EFFECTED BY A HOSTILE BIOPHYSICAL ENVIRONMENT The present invention generally relates to the transdermal delivery of substances In one aspect, various methods for the transdermal delivery of beneficial substances are disclosed. By creating a hostile biophysical environment, beneficial substances may be delivered, a... | 05/03/2012 |
| 20120014934 | Enhanced Natural Colors A natural color is concentrated to intensify color range and to provide useful amounts of one or more of anti-oxidant, nutritional, and anti-inflammatory compounds derived from one or more pigment sources. In a preferred embodiment, the pigment source is a fruit, a vege... | 01/19/2012 |
| 20120010291 | CREATINE Beta-ALANINATE: A NOVEL SALT FOR INCREASING ATHLETIC PERFORMANCE Disclosed are creatine β-alaninate, compositions and formulations containing same, and methods of use therefor.... | 01/12/2012 |
| 20120003158 | Biomarkers for Inflammatory Bowel Disease and Methods Using the Same The present invention provides various biomarkers of inflammatory bowel disease, including biomarkers for Crohn's disease and biomarkers for Ulcerative colitis. The present invention also provides various methods of using the biomarkers, including methods for diagnosis ... | 01/05/2012 |
| 20120004284 | PDK INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF The invention relates to methods of treating or preventing acquired or congenital mitochondrial diseases or disorders, including treating cell proliferation related disorders or diseases, such as cancer. The invention further relates to pharmaceutical compositions for t... | 01/05/2012 |
| 20110313011 | Amino Acid Compounds A method for increasing the bioabsorption of amino acids in a human or animal is disclosed. The method includes administering to the human or animal a pharmaceutically effective amount of an amino acid compound consisting essentially of a nitrate or nitrite of an amino ... | 12/22/2011 |
| 20110312882 | METHODS AND COMPOSITIONS FOR INCREASING THE ANAEROBIC WORKING CAPACITY IN TISSUES Provided are compositions comprising beta-alanylhistidine peptides and/or beta-alanines, and methods for administering these peptides and amino acids. In one aspect, the compositions and methods cause an increase in the blood plasma concentrations of beta-alanine and/or... | 12/22/2011 |
| 20110313042 | Amino Acid Compositions An amino acid composition is disclosed. The composition includes: at least one constituent selected from the group consisting of a nitrate, a nitrite, and both; and at least one constituent amino acid selected from the group consisting of Arginine, Agmatine, Beta Alanin... | 12/22/2011 |
| 20110313043 | Amino Acid Compositions Methods for increasing athletic performance, distribution of various Amino Acids to muscles, and solubility of various Amino Acids in a human or animal by administering an amino acid composition that includes: at least one constituent selected from the group consisting ... | 12/22/2011 |
| 20110313012 | Amino Acid Compounds A method for increasing the vasodilative characteristics of amino acids in a human or animal is disclosed. The method includes administering to the human or animal a pharmaceutically effective amount of an amino acid compound consisting essentially of a nitrate or nitri... | 12/22/2011 |
| 20110300232 | EFFECTS OF NITRIC OXIDE (NO) AND iNOS ON EXPRESSION AND SIGNAL TRANSDUCTION IN CANCER AND ITS USE IN DRUG DISCOVERY AND CANCER THERAPY DESIGN Nitric Oxide (NO) acts as double-edged sword, which induces and prevents cell death, depending on various factors. The mechanism for the NO regulation of cells is not fully understood. The present invention provides experiment design methods and therapy design methods l... | 12/08/2011 |
| 20110275649 | Combination therapy for the prevention of statin induced diabetes Novel combinations comprising HMG CoA reductase inhibitors, or statins, with partial fatty acid oxidation inhibitors (pFOXi), and methods for their use, are disclosed. These combinations are useful in preventing or reducing the risk of developing diabetes which results ... | 11/10/2011 |
| 20110269833 | Continuous Administration of Dopa Decarboxylase Inhibitors and Compositions for Same Disclosed herein are compositions that include for example the arginine salt of carbidopa, and methods for treating neurological or movement diseases or disorders such as restless leg syndrome, Parkinson's disease, secondary parkinsonism, Huntington's disease, Parkinson... | 11/03/2011 |
| 20110263540 | SMALL-MOLECULE INHIBITORS OF PROTEIN SYNTHESIS INACTIVATING TOXINS Small-molecule inhibitors of a protein synthesis inhibiting toxin, e.g., ricin, abrin, Shiga, and Shiga-like toxins, as well as methods of using the inhibitors are provided. Further provided are methods of identifying small-molecule inhibitors of a protein synthesis inh... | 10/27/2011 |
| 20110257202 | Therapeutic Compositions and Methods for Treating Chronic Kidney Disease Associated with a Metabolic Imbalance Disclosed herein are compositions and methods for treating chronic kidney disease and/or a metabolic imbalance. Specifically exemplified herein are methods involving the coadministration of a RAS inhibitor with a conjunctive agent that improves endothelial NO or endothe... | 10/20/2011 |
| 20110257075 | GUANIDINO ACETIC ACID USED AS AN ANIMAL FOOD ADDITIVE The present invention relates to the use of guanidinoacetic acid and/or salts thereof as feed additive, in predominantly vegetarian diets, in particular use being made of salts with hydrochloric acid, hydrobromic acid and phosphoric acid. The use proceeds especially in ... | 10/20/2011 |
| 20110257236 | SOLID SOLUTION OF VALINE, ISOLEUCINE, LEUCINE AND ITS MANUFACTURING METHOD [Problem] A valine, isoleucine, leucine mixture which is excellent in the reduction of bitter taste and improved dissolution speed is provided. [Solving Means] The above problem is solved by a solid solution composed of three amino acids of... | 10/20/2011 |
| 20110245345 | Topical Treatment Formulation of Natural Ingredients for Enhancing Sexual Response The present invention relates to a topical composition to enhance sexual response. The composition includes L-arginine, trans-resveratrol, and a topical carrier wherein L-arginine is present in an amount not greater than about 10% and trans-resveratrol is present in an ... | 10/06/2011 |
| 20110245344 | ARGININE DERIVATIVE AND COSMETIC CONTAINING THE SAME An object of the invention is to provide a novel arginine derivative and a cosmetic satisfactory in compatibility with the skin and hair, excellent in skin softening effect and skin-conditioning effect, and satisfactory in use feeling with little sticky feeling and tens... | 10/06/2011 |
| 20110236508 | L-ARGININE-BASED FORMULATION FOR ORAL ABSORPTION A formulation comprising large quantities of l-arginine and/or fat plaque dissolving agents which is palatable, stench free, and does not evoke nausea. The formulation is adapted to facilitate the adsorption of l-arginine to the blood system and to introduce high levels... | 09/29/2011 |
| 20110236502 | Vitamin Strip (V1) The vitamin strip is made with gel, film, or dissolvable material safe for human consumption. It can encompass all the vitamins, minerals, medicines, or meal replacement elements safe for human intake. The vitamin strip (V1) can be made as a whole or as a strip of edibl... | 09/29/2011 |
| 20110218158 | DNA CYTOSINE DEAMINASE INHIBITORS Cytosine deaminase inhibitors and methods for identifying inhibitors of the anti-retroviral activity of APOBEC3G are described.... | 09/08/2011 |
| 20110217364 | CONJUGATED SURAMIN AMINO COMPOUNDS FOR MEDICAL CONDITIONS A modification of pharmacokinetics of suramin by use of amino compounds in modification of lipophilicity and protein binding characteristics for tackling the physico-chemical properties of suramin that gives it poor distribution in the body; formulating the resulting pr... | 09/08/2011 |
| 20110213033 | SKIN CONDITIONER The present invention relates to a skin conditioner comprising the compound represented with the general formula: (wherein, the symbols are the same as those defined in the text). Examples of active ingredien... | 09/01/2011 |
| 20110213034 | Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same Disclosed are amphetamine prodrug compositions comprising at least one non-standard amino acid conjugate of amphetamine, a salt thereof, or a combination thereof, and methods of using the same.... | 09/01/2011 |
| 20110206781 | METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH Described herein are methods, compositions and kits related to manipulating hematopoietic stem cells (HSC) and more particularly to methods, compositions and kits related to increasing the number of hematopoietic stem cells in vitro, ex vivo and/or in vivo. Also describ... | 08/25/2011 |
| 20110195115 | HYDROPHILIC AMINO ACID-CONTAINING PREPARATION HAVING IMPROVED TASTE The present invention provides a hydrophilic amino acid-containing preparation wherein the taste of the hydrophilic amino acid is improved without damaging the appearance, flavor, storage stability and so on. It is further intended to provide a hydrophilic amino acid-co... | 08/11/2011 |
| 20110196039 | Controlled release arginine formulations A sustained release formulation of L-arginine alone or in combination with an agent which enhances the biotransformation of L-arginine into NO is described herein. FIG. 1A shows a schematic representation of proposed L-arginine dependent and independent pahtways.... | 08/11/2011 |
| 20110189110 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF XEROSTOMIA The present invention is directed to methods and compositions comprising a basic amino acid, e.g., arginine, for the treatment of dry mouth.... | 08/04/2011 |
| 20110171193 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY HYPERTENSION Provided herein are methods and materials for treating pulmonary hypertension (PH) in a subject. Also provided herein is a method of diagnosing whether a has PH by detecting a PH marker. A PKG pulmonary hypertension marker has been identified and may be useful in predic... | 07/14/2011 |
| 20110166232 | ENHANCEMENT OF UROGENITAL FUNCTION A method of treating nocturia in a human individual includes administering dosages of creatine to the individual; and reducing the dosages of creatine to the individual responsive to an increase in difficulty of the individual to initiate urination. Another example meth... | 07/07/2011 |
| 20110130460 | INCREASED CREATINE RETENTION WITH SOLUBLE FIBRES The present invention generally relates to increasing the efficiency of usage of an ingested biologically active substance by a body. In particular, the present invention relates to ways to improve the efficiency of utilization of ingested creatine in a body, in particu... | 06/02/2011 |
| 20110117219 | HAIR TREATMENT PRODUCT AND HAIR AFTER-TREATMENT PRODUCT CONTAINING ETHER GUANIDINES AS ACTIVE SUBSTANCES, FOR PROTECTING FROM DAMAGE CAUSED BY CHEMICAL TREATMENT AND FOR REPAIRING ALREADY DAMAGED HAIR The invention relates to ether guanidines of the general formulae (I) and/or salts or hydrates thereof, in which R1=—CH2—CH2—CH2—O—R3 where R | |
| 20110112188 | Treatment of Inflammatory Conditions The invention relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin thereby treating or prevention various diseases, disorders or conditions. Additionally, the invention relates to treatment of various dis... | 05/12/2011 |
| 20110085993 | USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION The present invention relates to the use of creatine compounds such as, for example, creatine, creatine phosphate or analogs of creatine, such as creatine-pyruvate, creatine-ascorbate, cyclocreatine, 3 guanidinopropionic acid, guanidinoacetate, homocyclocreatine, guanid... | 04/14/2011 |
| 20110077198 | COMPOSITIONS AND METHODS FOR INHIBITING THE ACTIVATION OF DSRNA-DEPENDENT PROTEIN KINASE AND TUMOR GROWTH INHIBITION The present invention relates to compositions and methods for preventing and treating a condition in a mammalian subject that include at least one inhibitor of double stranded RNA dependent protein kinase (PKR-I) prior to or concurrently with the treatment, wherein the ... | 03/31/2011 |
| 20110071168 | NITRIC OXIDE DONORS FOR INDUCING NEUROGENESIS There is provided a method of promoting neurogenesis by administering a therapeutic amount of a nitric oxide donor compound to a patient in need of neurogenesis promotion. Also provided is a compound for providing neurogenesis having an effective amount of a nitric oxid... | 03/24/2011 |
| 20110060046 | AGENT AND FOOD FOR PREVENTING/IMPROVING FUNCTIONAL DIGESTIVE DISORDER Provided is an agent for the prophylaxis or improvement of functional gastrointestinal disorders, which contains glutamic acid or a salt thereof other than arginine glutamate, and arginine or a salt thereof other than arginine glutamate, as active ingredients. The proph... | 03/10/2011 |
| 20110059906 | Energy status of an individual by enhanced production of an endogenous fuel source The present invention relates to a method of improving the energy status of an individual by enhancing the usage of lactate. Improved lactate usage is accomplished through a composition comprising lactate precursors, adrenergic receptor agonists and insulinotropic agent... | 03/10/2011 |