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Patent No. 5035252

Nicotine Containing Dental Floss

Keep away cavities and cancer at the same time.

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Class 514/565 - N-N or N=C(-N)-N containing (e.g., hydrazines, hydrazones, or quanidines, etc.)


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein two nitrogens are singly bonded to
No. of applications: 336
Last issue date: 05/24/2012


1                  
Application No.Application TitleIssue Date
20120128724SYSTEMS AND METHODS FOR TREATING HUMAN INFLAMMATORY AND PROLIFERATIVE DISEASES AND WOUNDS, WITH FATTY ACID METABOLISM INHIBITORS AND/OR GLYCOLYTIC INHIBITORS
Systems and methods for treating inflammatory and proliferative diseases, and wounds, using as a pharmacon a fatty acid metabolism inhibitor, a glycolytic inhibitor, and/or an agent able to alter cellular production of reactive oxygen, or combination thereof, optionally...
05/24/2012
20120108664TRANSDERMAL DELIVERY OF BENEFICIAL SUBSTANCES EFFECTED BY A HOSTILE BIOPHYSICAL ENVIRONMENT
The present invention generally relates to the transdermal delivery of substances In one aspect, various methods for the transdermal delivery of beneficial substances are disclosed. By creating a hostile biophysical environment, beneficial substances may be delivered, a...
05/03/2012
20120014934Enhanced Natural Colors
A natural color is concentrated to intensify color range and to provide useful amounts of one or more of anti-oxidant, nutritional, and anti-inflammatory compounds derived from one or more pigment sources. In a preferred embodiment, the pigment source is a fruit, a vege...
01/19/2012
20120010291CREATINE Beta-ALANINATE: A NOVEL SALT FOR INCREASING ATHLETIC PERFORMANCE
Disclosed are creatine β-alaninate, compositions and formulations containing same, and methods of use therefor....
01/12/2012
20120003158Biomarkers for Inflammatory Bowel Disease and Methods Using the Same
The present invention provides various biomarkers of inflammatory bowel disease, including biomarkers for Crohn's disease and biomarkers for Ulcerative colitis. The present invention also provides various methods of using the biomarkers, including methods for diagnosis ...
01/05/2012
20120004284PDK INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF
The invention relates to methods of treating or preventing acquired or congenital mitochondrial diseases or disorders, including treating cell proliferation related disorders or diseases, such as cancer. The invention further relates to pharmaceutical compositions for t...
01/05/2012
20110313011Amino Acid Compounds
A method for increasing the bioabsorption of amino acids in a human or animal is disclosed. The method includes administering to the human or animal a pharmaceutically effective amount of an amino acid compound consisting essentially of a nitrate or nitrite of an amino ...
12/22/2011
20110312882METHODS AND COMPOSITIONS FOR INCREASING THE ANAEROBIC WORKING CAPACITY IN TISSUES
Provided are compositions comprising beta-alanylhistidine peptides and/or beta-alanines, and methods for administering these peptides and amino acids. In one aspect, the compositions and methods cause an increase in the blood plasma concentrations of beta-alanine and/or...
12/22/2011
20110313042Amino Acid Compositions
An amino acid composition is disclosed. The composition includes: at least one constituent selected from the group consisting of a nitrate, a nitrite, and both; and at least one constituent amino acid selected from the group consisting of Arginine, Agmatine, Beta Alanin...
12/22/2011
20110313043Amino Acid Compositions
Methods for increasing athletic performance, distribution of various Amino Acids to muscles, and solubility of various Amino Acids in a human or animal by administering an amino acid composition that includes: at least one constituent selected from the group consisting ...
12/22/2011
20110313012Amino Acid Compounds
A method for increasing the vasodilative characteristics of amino acids in a human or animal is disclosed. The method includes administering to the human or animal a pharmaceutically effective amount of an amino acid compound consisting essentially of a nitrate or nitri...
12/22/2011
20110300232EFFECTS OF NITRIC OXIDE (NO) AND iNOS ON EXPRESSION AND SIGNAL TRANSDUCTION IN CANCER AND ITS USE IN DRUG DISCOVERY AND CANCER THERAPY DESIGN
Nitric Oxide (NO) acts as double-edged sword, which induces and prevents cell death, depending on various factors. The mechanism for the NO regulation of cells is not fully understood. The present invention provides experiment design methods and therapy design methods l...
12/08/2011
20110275649Combination therapy for the prevention of statin induced diabetes
Novel combinations comprising HMG CoA reductase inhibitors, or statins, with partial fatty acid oxidation inhibitors (pFOXi), and methods for their use, are disclosed. These combinations are useful in preventing or reducing the risk of developing diabetes which results ...
11/10/2011
20110269833Continuous Administration of Dopa Decarboxylase Inhibitors and Compositions for Same
Disclosed herein are compositions that include for example the arginine salt of carbidopa, and methods for treating neurological or movement diseases or disorders such as restless leg syndrome, Parkinson's disease, secondary parkinsonism, Huntington's disease, Parkinson...
11/03/2011
20110263540SMALL-MOLECULE INHIBITORS OF PROTEIN SYNTHESIS INACTIVATING TOXINS
Small-molecule inhibitors of a protein synthesis inhibiting toxin, e.g., ricin, abrin, Shiga, and Shiga-like toxins, as well as methods of using the inhibitors are provided. Further provided are methods of identifying small-molecule inhibitors of a protein synthesis inh...
10/27/2011
20110257202Therapeutic Compositions and Methods for Treating Chronic Kidney Disease Associated with a Metabolic Imbalance
Disclosed herein are compositions and methods for treating chronic kidney disease and/or a metabolic imbalance. Specifically exemplified herein are methods involving the coadministration of a RAS inhibitor with a conjunctive agent that improves endothelial NO or endothe...
10/20/2011
20110257075GUANIDINO ACETIC ACID USED AS AN ANIMAL FOOD ADDITIVE
The present invention relates to the use of guanidinoacetic acid and/or salts thereof as feed additive, in predominantly vegetarian diets, in particular use being made of salts with hydrochloric acid, hydrobromic acid and phosphoric acid. The use proceeds especially in ...
10/20/2011
20110257236SOLID SOLUTION OF VALINE, ISOLEUCINE, LEUCINE AND ITS MANUFACTURING METHOD
[Problem] A valine, isoleucine, leucine mixture which is excellent in the reduction of bitter taste and improved dissolution speed is provided.

[Solving Means] The above problem is solved by a solid solution composed of three amino acids of...

10/20/2011
20110245345Topical Treatment Formulation of Natural Ingredients for Enhancing Sexual Response
The present invention relates to a topical composition to enhance sexual response. The composition includes L-arginine, trans-resveratrol, and a topical carrier wherein L-arginine is present in an amount not greater than about 10% and trans-resveratrol is present in an ...
10/06/2011
20110245344ARGININE DERIVATIVE AND COSMETIC CONTAINING THE SAME
An object of the invention is to provide a novel arginine derivative and a cosmetic satisfactory in compatibility with the skin and hair, excellent in skin softening effect and skin-conditioning effect, and satisfactory in use feeling with little sticky feeling and tens...
10/06/2011
20110236508L-ARGININE-BASED FORMULATION FOR ORAL ABSORPTION
A formulation comprising large quantities of l-arginine and/or fat plaque dissolving agents which is palatable, stench free, and does not evoke nausea. The formulation is adapted to facilitate the adsorption of l-arginine to the blood system and to introduce high levels...
09/29/2011
20110236502Vitamin Strip (V1)
The vitamin strip is made with gel, film, or dissolvable material safe for human consumption. It can encompass all the vitamins, minerals, medicines, or meal replacement elements safe for human intake. The vitamin strip (V1) can be made as a whole or as a strip of edibl...
09/29/2011
20110218158DNA CYTOSINE DEAMINASE INHIBITORS
Cytosine deaminase inhibitors and methods for identifying inhibitors of the anti-retroviral activity of APOBEC3G are described....
09/08/2011
20110217364CONJUGATED SURAMIN AMINO COMPOUNDS FOR MEDICAL CONDITIONS
A modification of pharmacokinetics of suramin by use of amino compounds in modification of lipophilicity and protein binding characteristics for tackling the physico-chemical properties of suramin that gives it poor distribution in the body; formulating the resulting pr...
09/08/2011
20110213033SKIN CONDITIONER
The present invention relates to a skin conditioner comprising the compound represented with the general formula:

(wherein, the symbols are the same as those defined in the text). Examples of active ingredien...

09/01/2011
20110213034Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same
Disclosed are amphetamine prodrug compositions comprising at least one non-standard amino acid conjugate of amphetamine, a salt thereof, or a combination thereof, and methods of using the same....
09/01/2011
20110206781METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH
Described herein are methods, compositions and kits related to manipulating hematopoietic stem cells (HSC) and more particularly to methods, compositions and kits related to increasing the number of hematopoietic stem cells in vitro, ex vivo and/or in vivo. Also describ...
08/25/2011
20110195115HYDROPHILIC AMINO ACID-CONTAINING PREPARATION HAVING IMPROVED TASTE
The present invention provides a hydrophilic amino acid-containing preparation wherein the taste of the hydrophilic amino acid is improved without damaging the appearance, flavor, storage stability and so on. It is further intended to provide a hydrophilic amino acid-co...
08/11/2011
20110196039Controlled release arginine formulations
A sustained release formulation of L-arginine alone or in combination with an agent which enhances the biotransformation of L-arginine into NO is described herein. FIG. 1A shows a schematic representation of proposed L-arginine dependent and independent pahtways....
08/11/2011
20110189110COMPOSITIONS AND METHODS FOR THE TREATMENT OF XEROSTOMIA
The present invention is directed to methods and compositions comprising a basic amino acid, e.g., arginine, for the treatment of dry mouth....
08/04/2011
20110171193COMPOSITIONS AND METHODS FOR TREATING PULMONARY HYPERTENSION
Provided herein are methods and materials for treating pulmonary hypertension (PH) in a subject. Also provided herein is a method of diagnosing whether a has PH by detecting a PH marker. A PKG pulmonary hypertension marker has been identified and may be useful in predic...
07/14/2011
20110166232ENHANCEMENT OF UROGENITAL FUNCTION
A method of treating nocturia in a human individual includes administering dosages of creatine to the individual; and reducing the dosages of creatine to the individual responsive to an increase in difficulty of the individual to initiate urination. Another example meth...
07/07/2011
20110130460INCREASED CREATINE RETENTION WITH SOLUBLE FIBRES
The present invention generally relates to increasing the efficiency of usage of an ingested biologically active substance by a body. In particular, the present invention relates to ways to improve the efficiency of utilization of ingested creatine in a body, in particu...
06/02/2011
20110117219HAIR TREATMENT PRODUCT AND HAIR AFTER-TREATMENT PRODUCT CONTAINING ETHER GUANIDINES AS ACTIVE SUBSTANCES, FOR PROTECTING FROM DAMAGE CAUSED BY CHEMICAL TREATMENT AND FOR REPAIRING ALREADY DAMAGED HAIR
The invention relates to ether guanidines of the general formulae (I)

and/or salts or hydrates thereof, in which R1=—CH2—CH2—CH2—O—R3 where R

05/19/2011
20110112188Treatment of Inflammatory Conditions
The invention relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin thereby treating or prevention various diseases, disorders or conditions. Additionally, the invention relates to treatment of various dis...
05/12/2011
20110085993USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION
The present invention relates to the use of creatine compounds such as, for example, creatine, creatine phosphate or analogs of creatine, such as creatine-pyruvate, creatine-ascorbate, cyclocreatine, 3 guanidinopropionic acid, guanidinoacetate, homocyclocreatine, guanid...
04/14/2011
20110077198COMPOSITIONS AND METHODS FOR INHIBITING THE ACTIVATION OF DSRNA-DEPENDENT PROTEIN KINASE AND TUMOR GROWTH INHIBITION
The present invention relates to compositions and methods for preventing and treating a condition in a mammalian subject that include at least one inhibitor of double stranded RNA dependent protein kinase (PKR-I) prior to or concurrently with the treatment, wherein the ...
03/31/2011
20110071168NITRIC OXIDE DONORS FOR INDUCING NEUROGENESIS
There is provided a method of promoting neurogenesis by administering a therapeutic amount of a nitric oxide donor compound to a patient in need of neurogenesis promotion. Also provided is a compound for providing neurogenesis having an effective amount of a nitric oxid...
03/24/2011
20110060046AGENT AND FOOD FOR PREVENTING/IMPROVING FUNCTIONAL DIGESTIVE DISORDER
Provided is an agent for the prophylaxis or improvement of functional gastrointestinal disorders, which contains glutamic acid or a salt thereof other than arginine glutamate, and arginine or a salt thereof other than arginine glutamate, as active ingredients. The proph...
03/10/2011
20110059906Energy status of an individual by enhanced production of an endogenous fuel source
The present invention relates to a method of improving the energy status of an individual by enhancing the usage of lactate. Improved lactate usage is accomplished through a composition comprising lactate precursors, adrenergic receptor agonists and insulinotropic agent...
03/10/2011
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