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| Application No. | Application Title | Issue Date |
| 20120129930 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composi... | 05/24/2012 |
| 20120108658 | OPHTHALMIC COMPOSITION Disclosed is an ophthalmic composition which is characterized by containing (A) a vitamin A, (B) a polyoxyethylene polyoxypropylene glycol, and (C) an oil component that is selected from the group consisting of castor oil, soybean oil, sesame oil, peanut oil, olive oil,... | 05/03/2012 |
| 20120046354 | ANTI-OXIDANT LOZENGES FOR THE PREVENTION AND TREATMENT OF RADIATION INDUCED MUCOSITIS, PRECANCEROUS LESIONS, ORAL CANCER AND OTHER ORAL CAVITY MUCOSAL DISORDERS A method for treating or preventing oral cavity mucosal disorders, comprising a step of providing a lozenge containing an antioxidant selected from the group of Vitamin A, Vitamin C, Vitamin E; and other ingredients and a step of placing the lozenge within the oral cavi... | 02/23/2012 |
| 20120041029 | COMPOSITIONS FOR DRUG DELIVERY Substantially non-porous polymeric microparticles comprising a hydrophobic polymer and a plasticizer, and containing therein a bioactive or bioinactive agent.... | 02/16/2012 |
| 20120040025 | Compositions and Methods for Treating Disorders Associated with Salt or Fluid Retention Methods for reducing the risk of or treating a disorder associated with fluid and/or salt retention in a patient are described. The methods include administering to the patient an agent selected from: a) an agent that reduces sodium absorption in the intestine; b) an ag... | 02/16/2012 |
| 20120035141 | CYCLOALKYL-HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiova... | 02/09/2012 |
| 20120034205 | PKC ACTIVATORS AND ANTICOAGULANT IN REGIMEN FOR TREATING STROKE The present disclosure provides a method for treating stroke by administering to a subject an anticoagulant, e.g., recombinant tissue plasminogen activator (rTPA), and a protein kinase C (PKC) activator followed by administration of at least one PKC activator for a dura... | 02/09/2012 |
| 20120015001 | METHODS OF TREATING THYROID EYE DISEASE The present invention relates to a methods and compositions for the treatment of and management of symptoms for thyroid eye disease. The methods include administering to a patient having thyroid eye disease an agent that interferes with hyaluronan synthesis in an amount... | 01/19/2012 |
| 20120010288 | Method for protecting a retinal neuronal cell A method of protecting a retinal neuronal cell by administering an effective amount of a prostaglandin F2α derivative to a patient. A method of preventing or treating an eye disease associated with retinal neuronal cell damage by administering a therapeutically effecti... | 01/12/2012 |
| 20110319352 | Compounds That Bind Oxysterol Binding Proteins, and Methods of Use Thereof The invention relates in part to the discovery that certain CRAMs, such as schweinfurthin A, target OSBPs (a family of oxysterol binding proteins). Because OSBPs have been shown to be integral to atherosclerosis and Alzheimer's disease (AD), one aspect of the invention ... | 12/29/2011 |
| 20110318351 | NOVEL METHODS OF CANCER DIAGNOSIS AND THERAPY TARGETED AGAINST A CANCER STEM LINE Improved methods for treatment of cancer which involve the targeting of slow-growing, relatively mutationally-spared cancer stem line are provided. These methods are an improvement over previous cancer therapeutic methods because they provide for very early cancer treat... | 12/29/2011 |
| 20110312915 | Novel cosmetic compositions The present invention is concerned with novel cosmetic or pharmaceutical compositions. More particularly, the invention is concerned with novel cosmetic or pharmaceutical compositions for treating or preventing any symptoms caused by negative developments of the physiol... | 12/22/2011 |
| 20110300083 | PERSONAL CARE FORMULATIONS CONTAINING ALKYL KETAL ESTERS AND METHODS OF MANUFACTURE Personal care formulations containing alkyl ketal esters having the structure wherein a is 0 or an integer of 1 to 12; b is 0 or 1; R2 is a divalent C1-8 group optionally substituted wit... | 12/08/2011 |
| 20110294737 | TERMINALLY-DIFFERENTIATED ANUCLEATE PLATELET PROGENY GENERATION Platelets are induced to proliferate, form extensions and produce daughter cells by various methods, including culturing platelets under thrombocytopenic conditions. Expansion of platelet cell numbers increases the storage life of platelets. Modulation of RT activity ca... | 12/01/2011 |
| 20110288153 | TRANSLATION FACTORS AS ANTI-AGING DRUG TARGETS In certain embodiments this invention pertains to the discovery that inhibition of the expression and/or activity of eukaryotic initiation factor 4A (eIF4A) inhibits the aging process. Accordingly, in certain embodiments, methods are provided for inhibiting/slowing agin... | 11/24/2011 |
| 20110275715 | METHOD FOR TREATING RETINAL DISEASE The present application provides a method for treating a retinal disease in a patient in need thereof, which comprises administering at least three drops of an ophthalmic composition comprising a fatty acid derivative as an active ingredient in an eye of the patient per... | 11/10/2011 |
| 20110269691 | Compositions and Methods for Treating Pigmentary Conditions and Melanoma A method of treating a hypopigmentary condition in a subject comprising administering to the subject an amount of SOX9 sufficient to treat melanoma is disclosed. The hypopigmentary condition can be a result of surgery, trauma or vitiligo. A method of treating a hyperpig... | 11/03/2011 |
| 20110251242 | PHOTOSTABILIZATION OF RESVERATROL WITH ALKOXYCRYLENE COMPOUNDS The photostabilizing electronic excited state energy—particularly singlet state energy from resveratrol compounds—has been found to be readily transferred to (accepted by) α-cyanodiphenylacrylate compounds having an alkoxy radical in the four (para) position (herei... | 10/13/2011 |
| 20110251144 | MOLECULAR MODULATORS OF THE WNT/BETA-CATENIN PATHWAY The present invention is directed toward a method of treating a subject for a condition mediated by aberrant Wnt/β-catenin signaling by selecting a subject with a condition mediated by aberrant Wnt/β-catenin signaling and administering to the selected subject at least... | 10/13/2011 |
| 20110212157 | DERMAL DELIVERY The present invention describes systems and methods for treating disorders and/or conditions associated with the dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis, chromhidrosis, rosacea, hair loss, dermal infection, and/or actinic kerat... | 09/01/2011 |
| 20110206626 | Method for Treating Skin with Booster Compositions A skin care product comprising from about 0.001% to about 10% of a retinoid, in combination with 0.0001% to about 50% of a combination of retinoid boosters.... | 08/25/2011 |
| 20110190395 | NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT The present disclosure relates to lipid compounds of general formula (I) wherein R1 is chosen from a C10-C22 alkyl group, a C10-C22 alkenyl group having 1-6 double bonds, and a C10-C22 alkynyl ... | 08/04/2011 |
| 20110190307 | Assay The present invention provides zebrafish based methods for the identification of compounds potentially useful in the treatment of motor neuron degenerative diseases (MNDDs), compounds identified by these methods and compositions, methods and medicaments for treating MND... | 08/04/2011 |
| 20110177156 | Sterol-Modified Amphiphilic Lipids Disclosed are sterol-modified amphiphilic lipid compounds having two or more hydrophobic tails of which at least one is a sterol. Also disclosed are the processes for the synthesis of these compounds, compositions comprising such compounds, and the use of such compounds... | 07/21/2011 |
| 20110172299 | THERAPEUTIC SUBSTITUTED CYCLOPENTANES Disclosed herein are compounds represented by a formula: Therapeutic methods, compositions, and medicaments related thereto are also disclosed. ... | 07/14/2011 |
| 20110150981 | Compounds for Use in Therapy A compound of formula (I) for use in the treatment of a disease of the immune system; wherein R is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 50 carbon atoms; R1 is an optionally-substituted alkyl, ... | 06/23/2011 |
| 20110150955 | Products and Methods for Reducing Malodor from the Pudendum Products and methods are disclosed for reducing the production of unwanted odors from the pudendum.... | 06/23/2011 |
| 20110142771 | Photostabilization of Retinoids with Alkoxycrylene Compounds The photostabilizing electronic excited state energy—particularly singlet state energy from retinoid compounds—has been found to be readily transferred to (accepted by) α-cyanodiphenylacrylate compounds having an alkoxy radical in the four (para) position (hereinaf... | 06/16/2011 |
| 20110091387 | METHODS AND COMPOSITIONS FOR REDUCING SKIN DAMAGE The RhoE GTPase pathway has been identified as a target for screening and treatment methods for the prevention and/or reduction of short- and long-term UVB-induced skin damage, e.g., the prevention and/or reduction of UVB-induced wrinkles. The invention thus features sc... | 04/21/2011 |
| 20110081418 | TRANSDERMAL ABSORPTION ENHANCER An object of the present invention is to provide a transdermal absorption enhancer by which various active ingredients are transdermally absorbed. In accordance with a transdermal absorption enhancer of the present invention which effective ingredient is lyotropic liqui... | 04/07/2011 |
| 20110081410 | THERAPEUTIC AGENT FOR LOCAL INFLAMMATION The agents of the present invention comprise, as a main ingredient, a polyvalent metal inorganic-salt nanocapsule which encapsulates a retinoid such as retinoic acid. The agents could penetrate into a joint when applied to the skin and induce hyaluronic acid production ... | 04/07/2011 |
| 20110070224 | METHODS COMPOSITIONS AND DEVICES UTILIZING STINGING CELLS/CAPSULES FOR DELIVERING A THERAPEUTIC OR A COSMETIC AGENT INTO A TISSUE A delivery device including at least one stinging capsule and methods of use are described.... | 03/24/2011 |
| 20110064677 | LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention ... | 03/17/2011 |
| 20110059117 | Liquid Compositions Capable of Foaming and Including Active Agents, and Methods for Making or Developing Same A liquid composition suitable for topical use comprising is provided that includes a phospholipid foaming agent and at least one solvent; and a pharmaceutically acceptable active agent; wherein the liquid composition is capable of mechanically foaming without an additio... | 03/10/2011 |
| 20110059159 | NANOSCALE BOUND BILAYERS, METHODS OF USE AND PRODUCTION Methods for rapidly obtaining a nanoscale apolipoprotein bound phospholipid bilayer (NABB) associated with at least one membrane protein are provided. Also disclosed are methods for rapidly obtaining a NABB not associated with membrane proteins. Immunogenic compositions... | 03/10/2011 |
| 20110060014 | Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents The use of screening assays based on the role of human stearoyl-CoA desaturase-1 (“hSCD1”) in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL, total cholesterol, or production of secretions from mucous membranes, mono... | 03/10/2011 |
| 20110038905 | SKIN ANTI-AGING AGENT FOR EXTERNAL USE It is an object of the present invention to provide a skin anti-aging agent for external use which comprises highly safe protein nanoparticles having high transparency due to the small particle size and high permeability into skin. The present invention provides a skin ... | 02/17/2011 |
| 20110039930 | FAST-ACTING NAPROXEN COMPOSITION WITH REDUCED GASTROINTESTINAL EFFECTS The present invention relates to pharmaceutical formulations containing Naproxen and a delivery agent.... | 02/17/2011 |
| 20110003872 | MATERIAL FORMED FROM DENDRITIC MOLECULES CONTAINING ASSOCIATIVE GROUPS The present invention relates to a material comprising dendritic molecules each constituted of fragments that are at least bifunctional and of fragments that are at least trifunctional joined together by ester or thioester bridges, alone or in combination with amide or ... | 01/06/2011 |
| 20110002866 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT The described invention relates to delivery of compositions comprising at least one prostaglandin analog to prevent or reduce hair loss (e.g. brittle hair growth, thin hair growth, short hair growth, sparse hair growth) or alopecia associated with chemotherapy.... | 01/06/2011 |
