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| Application No. | Application Title | Issue Date |
| 20120128770 | TREATMENT OF INSULIN RESISTANCE AND OBESITY BY STIMULATING GLP-1 RELEASE The present invention relates to 1 or 2 C16-C18 acyl glycerol based compounds which are capable of activating G-protein coupled receptor 119 and thereby stimulate GLP-1 release. Compounds of the present invention are useful in the prophylaxis and/or treatment of metabol... | 05/24/2012 |
| 20120128773 | DESFESOTERODINE IN THE FORM OF A TARTARIC ACID SALT The invention concerns desfesoterodine in the form of a tartaric acid salt, in particular in the polymorphic “R form”, as well as a process for its production. In a second aspect, the invention concerns the desfesoterodine of the invention in a microencapsulated for... | 05/24/2012 |
| 20120129924 | USES OF SESQUITERPENE DERIVATIVES The present invention relates to a pharmaceutical composition for preventing or treating hyperlipidemia, fatty liver, diabetes and obesity comprising a sesquiterpene derivative as an active ingredient. The sesquiterpene derivatives of the present invention leads to decr... | 05/24/2012 |
| 20120129894 | Alkoxy Compounds for Disease Treatment The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these c... | 05/24/2012 |
| 20120108549 | NEUROPROTECTIVE COMPOUNDS AND THEIR USE Apocynin derivative compounds, active pharmaceutical ingredients, dosage forms, and methods of use thereof as neuroprotectants in the brain of mammals.... | 05/03/2012 |
| 20120108592 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF SALICYLANILIDES FOR TREATMENT OF HEPATITIS VIRUSES A new class of salicylanilides is described. These compounds show strong activity against hepatitis viruses.... | 05/03/2012 |
| 20120107428 | REPELLENTS FOR PESTIFEROUS SOCIAL WASPS Provided herein are essential oils and synthetic compounds, and combinations thereof, as repellent compositions for repelling insects, such as vespid social wasps (Vespidae), including yellowjackets, paper wasps, and hornets. Controlled release devices comprising these ... | 05/03/2012 |
| 20120108658 | OPHTHALMIC COMPOSITION Disclosed is an ophthalmic composition which is characterized by containing (A) a vitamin A, (B) a polyoxyethylene polyoxypropylene glycol, and (C) an oil component that is selected from the group consisting of castor oil, soybean oil, sesame oil, peanut oil, olive oil,... | 05/03/2012 |
| 20120052109 | Control of Parasites The invention concerns a composition for the treatment of varroa mite infestations in honeybee colonies, comprising a base layer and an active layer, wherein the active layer comprises an effective amount of an acaricidal compound.... | 03/01/2012 |
| 20120053133 | ANTISEPTIC AGENT COMPOSITION A novel antiseptic agent composition which has a wide antimicrobial spectrum and excellent antiseptic properties is provided. An antiseptic agent composition A contains a glycerin hydroxy fatty acid monoester that is an ester of glycerin and a hydroxy fatty acid having ... | 03/01/2012 |
| 20120053180 | CYCLOHEXANE ANALOGUES AS GPR119 AGONISTS This invention relates to a series of substituted cyclohexane containing analogues which are agonists of GPR119 intended to treat metabolic diseases mediated by GPR119 including Type I & II diabetes mellitus. Diabetes mellitus is an ever-increasing threat to human h... | 03/01/2012 |
| 20120045459 | Methods for Treating Autophagy-Related Disorders Methods for treating autophagy-related disorders with agents which modulate expression of the gene encoding tyrosine phosphatase receptor type sigma (PTPRS) or which modulate the biological activity of the PTPRS gene product (PTPsigma). Methods for modulating autophagy ... | 02/23/2012 |
| 20120046361 | ETHYL PYRUVATE COMPOSITIONS AND METHODS Compositions and methods are disclosed for use of ethyl pyruvate to boost energy, endurance, or to feel good, or to lose weight. Pharmaceutical preparations having ethyl pyruvate are disclosed herein as well.... | 02/23/2012 |
| 20120029075 | COMPOSITIONS CONTAINING C1 TO C7 ORGANIC ACID MONOGLYCERIDES AND GLYCEROL, THEIR PREPARATION AND USE AS ANTIBACTERIALS AND ANTI-MOULD AGENTS Described are antibacterial and anti-mould compositions containing high amounts of C1 to C7 organic acid mono-glycerides and glycerol, their preparation and their use in animal feedstuffs.... | 02/02/2012 |
| 20120003198 | Lutein/Zeaxanthin for glare protection The invention relates to the improvement of visual performance, particularly of visual performance in the darkness, by administration of a colorant that is capable of being incorporated into eye tissue and/or causing yellowing of eye tissue, especially carotenoids, such... | 01/05/2012 |
| 20120003158 | Biomarkers for Inflammatory Bowel Disease and Methods Using the Same The present invention provides various biomarkers of inflammatory bowel disease, including biomarkers for Crohn's disease and biomarkers for Ulcerative colitis. The present invention also provides various methods of using the biomarkers, including methods for diagnosis ... | 01/05/2012 |
| 20110318461 | PERACID AND 2-HYDROXY ORGANIC ACID COMPOSITIONS AND METHODS FOR TREATING PRODUCE Methods and compositions for treating produce to control microorganisms are provided. The method treats produce by contacting the surface of the produce with an aqueous solution comprising i) an organic peracid of the formula RC(O)OOH wherein R is methyl, ethyl, n-propy... | 12/29/2011 |
| 20110300095 | MALODOR NEUTRALIZING COMPOSITIONS COMPRISING UNDECYLENIC ACID OR CITRIC ACID Compositions comprising undecylenic acid or citric acid and certain esters are effective for reducing malodors. The esters are in the molecular weight range of between 150-200 when the acid is undecylenic acid and in the range of between 130-230 when the acid is citric ... | 12/08/2011 |
| 20110294882 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES The invention concerns novel derivatives of 3,3-diphenylpropylamines, methods for their preparation, pharmaceutical compositions containing the novel compounds, and the use of the compounds for preparing drugs. More particularly, the invention relates to novel prodrugs ... | 12/01/2011 |
| 20110294408 | METHOD AND COMPOSITION FOR WASHING POULTRY DURING PROCESSING The present invention relates to compositions including peroxyacetic acid and peroxyoctanoic acid and methods for reducing microbial contamination on poultry. The methods include the step of applying a mixed peroxycarboxylic acid composition to poultry.... | 12/01/2011 |
| 20110288170 | RETINAL DERIVATIVES AND METHODS FOR THE USE THEREOF FOR THE TREATMENT OF VISUAL DISORDERS Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.... | 11/24/2011 |
| 20110281945 | GASTRIC ACID SECRETION INHIBITOR, AND POTASSIUM CHANNEL INHIBITOR To provide a drug, quasi-drug, food or drink that can act as a gastric acid secretion suppressant or a potassium channel inhibitor by including a composition that can be safely used and can be inexpensively produced. Each of these products contains one or more cooling s... | 11/17/2011 |
| 20110281853 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING ATRIAL FIBRILLATION The present invention provides compositions and methods for treating or preventing atrial fibrillation (AF). In particular, the present invention provides administration of muscarinic receptor antagonists (e.g., M2-selective muscarinic receptor blockers), administered a... | 11/17/2011 |
| 20110269689 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS High penetration compositions (HPC) of a parent compound, which are capable of crossing biological barriers with high penetration efficiency. The HPCs are capable of being converted to parent drugs or parent drug-related compounds such as metabolites after crossing one ... | 11/03/2011 |
| 20110269722 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS The invention provides the compounds of formula (I) or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutical compositions comprising one or more compounds of formula I or intermediates thereof and one more of pharmaceutically acceptable c... | 11/03/2011 |
| 20110257266 | Therapeutic Regimen and Methods for Treating or Ameliorating Visual Disorders Associated Disclosed herein are therapeutic regimens for treating or ameliorating a visual disorder associate with an endogenous retinoid deficiency in a subject by administering a therapeutically effective amount of a synthetic retinal derivative or a pharmaceutically acceptable ... | 10/20/2011 |
| 20110257255 | COMPOSITION AND METHOD FOR INHIBITION OF NERVE TRANSMISSION The presently claimed and disclosed invention(s) provides a therapeutically effective composition and method of inhibiting nerve cell transmission. In a preferred embodiment of the presently claimed and disclosed invention(s), the treatment of neuropathic pain utilizing... | 10/20/2011 |
| 20110256097 | Treatment of Conditions that Increase in Severity and/or Occurrence During One or More Phases of the Menstrual Cycle Methods are provided for treating a subject for a condition. In accordance with the subject methods, at least a portion of a subject's autonomic nervous system is modulated during at least one predetermined phase of the subject's menstrual cycle to alter the parasympath... | 10/20/2011 |
| 20110251195 | ADRB2 GENE POLYMORPHISM ASSOCIATED WITH INTRAOCULAR PRESSURE RESPONSE TO TOPICAL BETA-BLOCKERS The invention provides a single nucleotide polymorphism (SNP) rs1042714 in the human ADRB2 gene (Gln27Glu) associated with a clinically meaningful reduction in intraocular pressure (IOP) in a human following treatment with a topical beta-blocker. Nucleic acids comprisin... | 10/13/2011 |
| 20110250248 | External preparation for skin An external preparation for the skin containing isononyl 2-ethylhexanoate and/or 2-ethylhexyl 2-ethylhexanoate (i.e., component (a)); an oil-in-water emulsion type skin cosmetic composition containing the ingredient (a), (b) one or more ingredients selected from higher ... | 10/13/2011 |
| 20110250154 | COSMETIC COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOLS AND DERIVATIVES AND USES THEREOF Cosmetic methods and compositions for preventing or reversing damage caused to the skin of a subject by environmental pollution and/or UV radiation, the methods and compositions comprising isolated polyhydroxylated fatty alcohols or derivatives thereof for topical appli... | 10/13/2011 |
| 20110244051 | PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF OVERACTIVE BLADDER Disclosed herein are pharmaceutical compositions comprising a plurality of first beads each comprising: a core; a first layer comprising pilocarpine or a pharmaceutically acceptable salt thereof; and a second layer comprising a first polymer. Also disclosed are pharmace... | 10/06/2011 |
| 20110243883 | POLYMERIC BIOLUBRICANTS FOR MEDICAL USE The present invention provides branched polymers which can be used as lubricants or shock absorbers in vivo. For example, the inventive polymers can be used as viscosupplements, viscoelastics, tissue space fillers, and/or anti-adhesive agents. Also provided are pharmace... | 10/06/2011 |
| 20110245338 | CHIRAL INTERMEDIATE, PROCESS FOR PRODUCING THE SAME AND ITS USE IN THE MANUFACTURE OF TOLTERODINE, FESOTERODINE, OR THE ACTIVE METABOLITE THEREOF The compound of formula (I): is provided. It may be produced by subjecting a compound of formula (IV) to a reduction reaction wherein R represents hydrogen, straight or branched C1-C6 alkyl. This compound is a valuable intermediate which may be use... | 10/06/2011 |
| 20110245337 | METHOD FOR ENHANCING THE DNA REPAIR PROCESS, TREATING DISORDERS ASSOCIATED WITH THE DNA REPAIR PROCESS, ENHANCING ANTITUMOR RESPONSE AND TREATING DISORDERS ASSOCIATED WITH ANTI-TUMOR RESPONSE IN MAMMALS BY ADMINISTERING PURIFIED QUINIC ACID AND/OR CARBOXY ALKYL ESTER For use in mammals, methods for enhancing the anti-tumor response and treating disorders associated with anti-tumor response. The methods generally comprise non-topical administration of purified, isolated quinic acid alkyl acid or a carboxy alkyl ester with a non-toxic... | 10/06/2011 |
| 20110245340 | Screening Method for Identifying Patients at Risk of Adverse Hepatologic Events This present invention provides methods and kits for identifying patients at risk of suffering from a drug induced liver injury, particularly for an antioxidant drug, or for identifying patients who are suffering from early stages of a liver disorder by assessing the le... | 10/06/2011 |
| 20110237666 | HYDROXYBUTYRATE ESTER AND MEDICAL USE THEREOF A compound which is 3-hydroxybutyl 3-hydroxybutyrate enantiomerically enriched with respect to (3R)-hydroxybutyl (3R)-hydroxybutyrate of formula (I) is an effective and palatable precursor to the ketone body (3R)-hydroxybutyrate and may therefore be used to treat a cond... | 09/29/2011 |
| 20110237555 | USE OF 2,5-DIHYDROXYBENZENE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT OF ROSACEA The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, rosacea.... | 09/29/2011 |
| 20110224297 | Methods of administering prostratin and structural analogs thereof This invention relates generally to methods for administering prostratin or a structural analog or metabolite thereof to induce latent HIV-1 expression in mammalian cells. In certain embodiments, prostratin or a structural analog or metabolite thereof is administered by... | 09/15/2011 |
| 20110223264 | Substancefor Restoring Normal Co-expression and Interaction Between the LOX and NRAGE Proteins The invention relates to a substance for restoring normal co-expression and interaction between the LOX and NRAGE proteins. The invention relates in particular to the use of an effective amount of at least one substance that modulates the e... | 09/15/2011 |
