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Patent No. 5285430

Behavior Modification Wristwatch

A wristwatch including a watch band and a watch body having an octagon shaped perimeter and being red in color and having the word STOP thereon to resemble a stop sign.

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Class 514/502 - Iron


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the heavy metal is iron.
No. of applications: 68
Last issue date: 02/16/2012


1    
Application No.Application TitleIssue Date
20120039969SWELLABLE DOSAGE FORM COMPRISING GELLAN GUM
A novel dosage form. The dosage form is presented in particulate form and before oral ingestion the particulate material is subjected to an aqueous medium, whereby it is converted to a semi-solid form by swelling or gelling of one or more of the components, especially o...
02/16/2012
20120027832USE OF EDDS AND CALCIUM IONS AS ENHANCERS OF MOLLUSCICIDAL ACTIVITY
A molluscicidal composition, comprising: a molluscicide; a molluscicidal activity promoting additive comprising a calcium-containing salt of ethylene disuccinic acid or calcium ions and ethylenediamine disuccinic moieties, having at least 1 mole of calcium per mole of e...
02/02/2012
20120021010ANTIPLATELET AGENT AND METHODS OF USING THE SAME
Disclosed herein are compositions and methods for inhibiting platelet aggregation in a patient in need thereof. The compositions and methods use superparamagnetic iron oxide nanoparticles (SPIONs), which are shown to inhibit aggregation of platelets. Such methods are us...
01/26/2012
20120010213ORAL CONTROLLED RELEASE DOSAGE FORMS FOR WATER SOLUBLE DRUGS
Disclosed herein is an oral controlled release pharmaceutical formulation comprising water-soluble drug or pharmaceutically acceptable salts thereof, in a hydrophilic matrix system, further comprising pH independent polymers present in an amount of 5% to 90% w/w in comb...
01/12/2012
20110288162TRANSITION METAL COMPLEXES OF A BIS[THIO-HYDRAZIDE AMIDE] COMPOUNDS
The present invention is directed to a compound comprising a bis[thiohydrazide amide] or a deprotonated form thereof, complexed to a transition metal cation, wherein the bis[thio-hydrazide amide] is represented by Structural Formula (I): or a prodrug, isomer, ester, sal...
11/24/2011
20110206781METHOD TO MODULATE HEMATOPOIETIC STEM CELL GROWTH
Described herein are methods, compositions and kits related to manipulating hematopoietic stem cells (HSC) and more particularly to methods, compositions and kits related to increasing the number of hematopoietic stem cells in vitro, ex vivo and/or in vivo. Also describ...
08/25/2011
20110196033PROPHYLACTIC/AMELIORATING AGENT FOR ADULT DISEASES COMPRISING 5-AMINOLEVULINIC ACID, DERIVATIVE OF 5-AMINOLEVULINIC ACID, OR SALT OF 5-AMINOLEVULINIC ACID OR THE DERIVATIVE OR 5-AMINOLEVULINIC ACID AS ACTIVE INGREDIENT
It is to provide a pharmaceutical composition which is different from an existing therapeutic agent of an adult disease, of a biochemical reaction-inhibiting type, and which action mechanism is to improve the basal metabolism, wherein the composition has no side effects...
08/11/2011
20110190391FERROCENE DERIVATIVES WITH ANTICANCER ACTIVITY
The present invention relates to compounds of the following formula (I):

and to the pharmaceutically acceptable salts thereof, to the isomers and the mixtures of isomers thereof and to the water-soluble deriv...

08/04/2011
20110171187DIETARY SUPPLEMENTS FOR PROMOTION OF GROWTH, REPAIR, AND MAINTENANCE OF BONE AND JOINTS
The present invention provides a dietary supplement that promote the growth, repair, and maintenance of mammalian bone and joint connective tissue. In particular, the dietary supplement comprises a combination of at least one metal chelate and at least one chondroprotec...
07/14/2011
20110104308Treatment For Diseases Relying On Discovery That Thioredoxin Mediates Nitric Oxide
Patients having a disease associated with high level of thioredoxin system activity or a requirement for nitric oxide, e.g. large cell lymphoma or restenosis, are treated with a thioredoxin reductase inhibitor, e.g. auranofin or arsenic trioxide, and a nitric oxide dona...
05/05/2011
20110105419PHARMACOLOGICAL ADJUVANTS BASED ON COORDINATION COMPOUNDS OF D-METALS
The invention relates to the use of small and ultra small quantities of bi- and oligo-nuclear forms of the coordination compounds of d-metals in the form of drugs or agents for enhancing the therapeutic efficiency of pharmacological substances....
05/05/2011
20110091383FENRETINIDE DERIVATIVES AND USES THEREOF AS THERAPEUTIC, DIAGNOSTIC AND IMAGING AGENTS
Synthetic peptidomimetic derivatives and phenyl group derivatives of Fenretinide (4-HPR) are disclosed, as are their uses as therapeutic, diagnostic and imaging agents for cancer and other diseases....
04/21/2011
20110081425PESTICIDAL COMPOSITIONS AND METHODS
The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof...
04/07/2011
20110065787THERAPEUTIC AGENT FOR MALE STERILITY
The present invention is intended to provide an agent for treating male infertility which is highly effective to male infertility, and having few side effects. To achieve the object, an agent for treating male infertility comprising δ-amino levulinic acid shown by gene...
03/17/2011
20110060042EXTERNAL PREPARATION FOR SKIN
The present invention provides an external preparation for skin which contains 5-aminolevulinic acids as active components and which is excellent in skin-beautifying effects such as prevention/amelioration of skin roughness, dry skin, wrinkles, sagging and flecks of ski...
03/10/2011
20110060041METHOD OF REVERSING, PREVENTING, DELAYING OR STABILIZING SOFT TISSUE CALCIFICATION
The present invention provides methods of treating soft tissue calcification in a subject, comprising a step of administering to said subject an effective amount of ferric organic compound, such as ferric citrate. The claimed methods may prevent, reverse, delay or stabi...
03/10/2011
20110054019Cancer Starvation Therapy
The present invention is a glutamine analogue which enters the mitochondrion and is subsequently exposed to ionizing radiation. When exposed to ionizing radiation, the present invention damages mitochondrial (as well as other) substructures such as mtDNA, the outer memb...
03/03/2011
20110039927COMPOSITIONS COMPRISING AND PROCESSES FOR PRODUCING INORGANIC SALTS OF HOP ACIDS
The invention relates to compositions and processes for producing novel hop acid formulations having improved bioavailability, and the use of such compositions as anti-inflammatory agents, dietary supplements, and pharmaceuticals....
02/17/2011
20110021629IRON PREPARATION SUITABLE FOR PHARMACEUTICAL FORMULATION AND PROCESS FOR THE PREPARATION THEREOF
New iron preparations comprising stable, unpolymerized iron(III) citrate complex compositions and methods for their preparation are provided. Further, the invention involves the use stable, unpolymerized iron(III) citrate complex compositions of the invention as a food ...
01/27/2011
20110021461COMBINATIONS TO IMPROVE ANIMAL HEALTH AND PERFORMANCE
The present invention provides combinations of dietary supplements and methods of using of these combinations to improve the health and production performance of animals. In particular, the combinations of the invention comprise antioxidants, trace minerals, organic aci...
01/27/2011
20110015263THERAPEUTIC DELIVERY OF CARBON MONOXIDE
Compounds, pharmaceutical compositions and methods for the therapeutic delivery of carbon monoxide to humans and other mammals that employ transition metal complexes having at least a substituted cyclopentadienyl, indenyl or fluorenyl ligand and two or more carbonyl lig...
01/20/2011
20110014256LONG-LASTING ANTI-MICROBIAL COMPOSITION AND ANTI-MICROBIAL FILM AND SPRAY THEREOF
A long-lasting anti-microbial composition is provided, which includes one or more polymer or oligomer and a plurality of nanowires distributed therein, wherein the nanowires have an aspect ratio of more than 20 and the nanowires form a network-like structure. An anti-mi...
01/20/2011
20100273763ORGANOMETALLIC COMPLEXES AS THERAPEUTIC AGENTS
This invention comprises salophene-based metallic complexes. Included are metal-chelating analogues, and method of their preparation and use. These analogues have therapeutic activity including anticancer activity....
10/28/2010
20100260676PRECISION-GUIDED NANOPARTICLE SYSTEMS FOR DRUG DELIVERY
A method of preparing multifunctionalized nanoparticles involves using a modular system of half-linkers to attach functional moieties that serve to deliver the nanoparticles to a desired target, exert an effect at the target, or track the nanoparticles within a cell or ...
10/14/2010
20100247454COMPOSITIONS FOR ELASTOGENESIS AND CONNECTIVE TISSUE TREATMENT
The present invention describes therapeutic compositions comprising one or more minerals, including trivalent iron, divalent manganese and salts thereof, suitable in facilitating synthesis and deposition of connective tissue matrix, particularly rich of elastin and coll...
09/30/2010
20100190850WATER-SOLUBLE BINUCLEAR NITROSYL IRON COMPLEXES WITH NATURAL ALIPHATIC THIOLYLS POSSESSING CYTOTOXIC, APOPTOTIC AND NO-DONOR ACTIVITY
The present invention relates to water-soluble binuclear cationic nitrosyl iron complexes with natural aliphatic thiolyls of general formula [Fe2(SR)2(NO)4]SO4,
  • 07/29/2010
20100152131METHOD FOR PRODUCING PURIFIED HEMATINIC IRON-SACCHARADIC COMPLEX AND PRODUCT PRODUCED
A method for separating and purifying the active hematinic species (AHS) present in iron-saccharidic compositions, including AHS such as sodium ferric gluconate complex, ferric hydroxide-sucrose complex and ferric saccharate complex and others of similar form and functi...
06/17/2010
20100135950Iron(II)-Containing Treatments for Hyperphosphatemia
A pharmaceutical composition comprises a pharmaceutically acceptable ferrous iron compound; an amine polymer or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. Alternatively, a pharmaceutical composition comprises a pharmaceuticall...
06/03/2010
20100119608Synthesis of pH-sensitive, Acid-Stable Metal-Binding Nanoparticles
Among natural mechanisms of cell deaths, disease or toxicity, one of the most common method is through overloading of certain biological metals such as calcium, iron and zinc. We propose to utilize this natural mechanism of cell death against cancer by utilizing the wel...
05/13/2010
20100062039Intravaginal Ringed Mesh Device And Applicator Therefor
This invention generally covers a ringed-mesh intravaginal device and applicator therefore wherein the ringed-mesh comprises a composite ring comprising a flexible matrix containing one or more bioactive agent or agents and needed excipients or modulators, and the said ...
03/11/2010
20100032374PHOSPHATE BINDING MATERIALS AND THEIR USES
Phosphate binding materials and compositions comprising them which are solid ligand-modified poly oxo-hydroxy metal ion materials are disclosed that are based on ferric iron oxo-hydroxides modified with carboxylic acid ligands, or ionised forms thereof. These materials ...
02/11/2010
20100003353Control of Blood Vessel Physiology to Treat Skin Disorders
In a method for treating an affected skin region of a patient having a skin disorder, a vasodilation composition is applied to an affected skin region of a patient, the affected skin region exhibiting a skin disorder characterized by at least one abnormal blood vessel, ...
01/07/2010
20090326060Method of Reversing, Preventing, Delaying or Stabilizing Soft Tissue Calcification
The present invention provides methods of treating soft tissue calcification in a subject, comprising a step of administering to said subject an effective amount of ferric organic compound, such as ferric citrate. The claimed methods may prevent, reverse, delay or stabi...
12/31/2009
20090326061APOPTOTIC AND ANTI-TUMOR ACTIVITIES OF METALLO-SALENS
The present invention describes the synthesis and biochemical activities of metallo-salen compounds and their derivatives. The Mn(III)-salen and Fe(III)-salen derivatives of the present invention are potential anti-tumor agents, that affect cell viability, induce strong...
12/31/2009
20090246254NON-HORMONAL VAGINAL CONTRACEPTIVE
The present invention relates to a non-hormonal, biocompatible, and biodegradable intravaginal device for the delivery of spermiostatic, spermicidal and anti-infectious agents. The present invention also relates to methods of contraception using such a device, as well a...
10/01/2009
20090239946Pharmaceutical compositions of HDAC inhibitors and chelatable metal compounds, and metal-HDAC inhibitors chelate complexes
The present invention provides pharmaceutical compositions of an HDAC inhibitor and a chelatable metal compound. In one embodiment, the invention provides a method of treating cancer and alleviating the side effects of the HDAC inhibitor by administering the pharmaceuti...
09/24/2009
20090186939Method of Treating Chronic Kidney Disease
The present invention discloses pharmaceutical-grade ferric organic compounds having enhanced dissolution rate. These ferric organic compounds, including but are not limited to ferric citrate, are useful for treating chronic kidney disease....
07/23/2009
20090182044NITRATE AMINO ACID CHELATES
The present invention is directed to methods and compositions which include nitrate amino acid chelates that can increase the metabolic activity or metal concentration in animals and that can increase metabolic activity and nitrogen content in plants. In one embodiment,...
07/16/2009
20090170933METHOD FOR REMOVING A MEDICAL DEVICE FROM A SPASMODIC CONSTRICTION IN A BODILY PASSAGEWAY
A method and apparatus for removing a medical device entrapped in a bodily passageway resulting from a spasmodic constriction of bodily tissue surrounding the device involves delivering to the site of the constriction an amount of an antispasmodic agent sufficient to re...
07/02/2009
20090169484IRON-SALEN COMPLEX
The present invention provides a drug delivery system that overcomes conventional technical problems and that is readily put to practical use. Iron-salen complexes represented by General Formula (I) below. The invention renders iron-salen complexes magnetic, which can t...
07/02/2009
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