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| Application No. | Application Title | Issue Date |
| 20120128724 | SYSTEMS AND METHODS FOR TREATING HUMAN INFLAMMATORY AND PROLIFERATIVE DISEASES AND WOUNDS, WITH FATTY ACID METABOLISM INHIBITORS AND/OR GLYCOLYTIC INHIBITORS Systems and methods for treating inflammatory and proliferative diseases, and wounds, using as a pharmacon a fatty acid metabolism inhibitor, a glycolytic inhibitor, and/or an agent able to alter cellular production of reactive oxygen, or combination thereof, optionally... | 05/24/2012 |
| 20120070473 | Apparatus and Method for Reducing the Occurrence of Post-Surgical Adhesions A method for inhibiting formation of adhesions following abdominal surgery which involves application of an anti-static fatty acid ethoxylated amide (Cocamide DEA) in a matrix that is placed in the peritoneal cavity at the conclusion of an abdominal surgery and which re... | 03/22/2012 |
| 20120070519 | METHOD FOR EXTRACTION OF FRACTIONS CONTAINING PHARMACOLOGICALLY ACTIVE INGREDIENTS WITH LESS CYTOTOXICITY FROM ONE OR MORE PLANTS A method of obtaining one or more fractions from one or more plants is disclosed. The method includes subjecting one or more parts of the one or more plants to hydro-alcoholic extraction in presence of a water-insoluble solvent to obtain one or more extracts. The method... | 03/22/2012 |
| 20120053133 | ANTISEPTIC AGENT COMPOSITION A novel antiseptic agent composition which has a wide antimicrobial spectrum and excellent antiseptic properties is provided. An antiseptic agent composition A contains a glycerin hydroxy fatty acid monoester that is an ester of glycerin and a hydroxy fatty acid having ... | 03/01/2012 |
| 20120053155 | SYSTEM AND METHOD FOR REVERTING ANTIBIOTIC TOLERANCE OF BACTERIAL PERSISTER CELLS A system and method for reverting the antibiotic tolerance of persister cells. Brominated furanones, which are quorum sensing inhibitors, are used to revert the antibiotic tolerance of persister cells and enhance their susceptibility to antibiotics by up to one hundred ... | 03/01/2012 |
| 20120035224 | Betulin derived compounds as anti-feedants for plant pests The invention relates to compounds derived from betulin, and to the use thereof in plant pest control, particularly as antifeedants for butterfly larvae, beetles and snails. Further, the invention relates to novel betulin derivatives and methods for the production there... | 02/09/2012 |
| 20120035141 | CYCLOALKYL-HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiova... | 02/09/2012 |
| 20120029070 | BURDOCK FRUIT EXTRACT CONTAINING ARCTIGENIN AT HIGH CONTENT AND PROCESS FOR PRODUCING SAME PROBLEM TO BE SOLVED A burdock fruit extract containing arctigenin at high content and its production method are provided, and both of which are used for treatment of pancreatic cancer. SOLUTION 02/02/2012 | |
| 20120015923 | USE OF ANDROGRAPHOLIDE COMPOUNDS FOR TREATING INFLAMMATION AND AIRWAY DISORDERS We describe for the first time that andrographolide derivatives such as DDAG effectively reduced OVA-induced inflammatory cell recruitment into BAL fluid, IL-4, IL-5, IL-13 and eotaxin production, serum IgE synthesis, pulmonary eosinophilia, mucus hypersecretion and AHR... | 01/19/2012 |
| 20120010282 | Tautomycetin and Tautomycetin Analog Biosynthesis The present invention relates to the biosynthetic gene cluster for tautomycetin (TTN) produces tautomycetin. Also provided are engineered micro-organisms for the production of TTN and analogs thereof, as well as methods of screening for compounds for activity.... | 01/12/2012 |
| 20120010159 | COMBINATION THERAPIES WITH COX-2 INHIBITORS AND TREPROSTINIL The present invention is directed to compositions and methods for pain management, and for treating inflammation or an inflammation-associated disorder in a subject comprising administering to the subject a therapeutically effective amount of a COX-2 inhibitor and a the... | 01/12/2012 |
| 20120004232 | 2-AMINO-BICYCLO(3.1.0) HEXANE-2, 6-DICARBOXYLIC ESTER DERIVATIVE A drug effective for the treatment and prevention of psychiatric disorders such as schizophrenia, anxiety and related ailments thereof, depression, bipolar disorder and epilepsy. The drug antagonizes the action of group II metabotropic glutamate receptors and shows high... | 01/05/2012 |
| 20110319399 | EXTERNAL PREPARATION CONTAINING ANALGESIC/ANTI-INFLAMMATORY AGENT An external preparation containing the following components (A) and (B):
| 12/29/2011 |
| 20110311591 | Antimicrobial Coating A substrate (100) comprising a sol-gel derived coating (101). The coating, is chemically bonded to the substrate (100) and is derived from a polysiloxane to form a network of silicon-carbon and silicon-oxygen bonds. An antimicrobial is releasably captured within the net... | 12/22/2011 |
| 20110300247 | FLAXSEED LIGNAN COMPLEX AND ITS USE THEREOF The invention relates compositions and methods for treating pathological lung conditions using whole-grain flaxseed or flaxseed lignans. Specifically, the invention relates to the dietary use of flaxseed lignans.... | 12/08/2011 |
| 20110294783 | Insecticidal Compositions Having Improved Effect The present invention concerns boosting the activity of crop protection materials comprising inhibitors of fatty acid biosynthesis (for example phenyl-substituted cyclic ketoenols) through the addition of ammonium salts and/or phosphonium salts or through the addition o... | 12/01/2011 |
| 20110286993 | USE OF HSP70 AS A REGULATOR OF ENZYMATIC ACTIVITY The present invention concerns a method for modulating the enzymatic activity of an enzyme, wherein said enzyme interacts with BMP, said method comprising the step of administering or inducing Hsp70, or a functional fragment or variant thereof, in a form suitable for al... | 11/24/2011 |
| 20110281942 | Tautomycetin and Tautomycetin Analog Biosynthesis The present invention relates to tautomycetin (TTN) and analogs thereof. Also provided are methods of using TTN and analogs thereof in the treatment of various diseases relating to SHP2 function.... | 11/17/2011 |
| 20110251230 | THERAPEUTICS FOR NEUROLOGICAL DISORDERS The present invention relates to therapeutic compounds that are Nrf2-ARE pathway activators suitable for the treatment of diseases known to be mediated by oxidative stress such as motor neurone disease. The invention also includes compounds identified by methods of the ... | 10/13/2011 |
| 20110230346 | Biphenyl-Substituted Cyclic Ketoenols The invention relates to novel compounds of the formula (I)
| 09/22/2011 |
| 20110224196 | TREATMENT OF OBSTRUCTIVE SLEEP APNEA SYNDROME WITH A COMBINATION OF A CARBONIC ANHYDRASE INHIBITOR AND AN ADDITIONAL ACTIVE AGENT This invention relates generally to methods and pharmaceutical formulations useful in treating patients suffering from obstructive sleep apnea syndrome (OSAS). Treatment of OSAS is effected by administering a carbonic anhydrase inhibitor to the patient in combination wi... | 09/15/2011 |
| 20110212194 | Composition for Inhibiting Melanogenesis and Use Thereof The present invention provides a Cinnamomum subavenium extract for inhibiting melanogenesis. The present invention also provides a composition for inhibiting melanogenesis including compounds inhibit tyrosinase activity.... | 09/01/2011 |
| 20110212974 | METHOD FOR IDENTIFYING COMPOUNDS USEFUL FOR TREATING AND/OR PREVENTING DISEASE-ASSOCIATED BONE LOSS The present invention concerns a method for identifying a compound which inhibits the activation of RAC GTPase by DOCK5 protein comprising the steps of (i) coexpressing the DOCK5 and the RAC proteins in a cell, wherein said DOCK5 protein induces the conversion of inacti... | 09/01/2011 |
| 20110207724 | PHARMACEUTICAL FORMULATIONS AND METHODS OF USE WHICH COMBINE NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS WITH ANIT-HYPERTENSIVE COMPOUNDS An oral dosage form of a non-steroidal anti-inflammatory drug (NSAID) is rendered safer for extended or chronic use for anti-inflammatory, analgesic or antipyretic therapy by combining it with an antihypertensive drug. The antihypertensive drug acts prophylactically to ... | 08/25/2011 |
| 20110200597 | SIGNAL PATHWAY ALTERATIONS AND DRUG TARGET ELEVATIONS IN PRIMARY METACHRONOUS METASTATIC COLORECTAL CANCER COMPARED TO NON-METASTATIC DISEASE The present invention relates to the identification and diagnostic use of biomarkers in primary colorectal cancer tumors whose activation level are predictive of the likelihood of the onset of metastatic disease. These biomarkers may be used to determine the suitability... | 08/18/2011 |
| 20110201666 | COMPOUNDS FROM MYCELIUM OF ANTRODIA CINNAMOMEA AND USE THEREOF The present invention relates to compounds from mycelium of Antrodia cinnamomea. The present invention also relates to a composition and a method for treating or prophylaxis of hepatitis C virus (HCV) infection.... | 08/18/2011 |
| 20110190234 | MYCOBACTERIUM MEMBRANE PROTEASE AS A TARGET FOR INHIBITORS OF INTRABACTERIAL pH HOMEOSTASIS The present invention is directed to methods and compounds for inhibiting bacterial growth and treating a bacterial infection in a subject. These methods involve providing an inhibitor of intrabacterial pH homeostasis, including inhibitors of the Mycobacterium tuberc... | 08/04/2011 |
| 20110184059 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS The present invention relates to novel methylene furanone derivatives as well as the use thereof as a protective, antioxidant, or depigmentation agent in cosmetic or dermatological compositions. The invention also relates to a method for pr... | 07/28/2011 |
| 20110178165 | TETRAHYDROFURANYL SULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF The invention is directed to a class of compounds, including the pharmaceutically acceptable salts of the compounds, having the structure of formula (I): as defined in the specification. The invention is also directed to compositions containing the compounds of formula ... | 07/21/2011 |
| 20110158983 | COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES In alternative embodiments, this invention provides compositions and methods for treating cancer or any condition caused by dysfunctional cells, side effects from treatments for cancer or any condition caused by dysfunctional cells, e.g., mucositis therapies (e.g., for ... | 06/30/2011 |
| 20110151024 | Compositions and Methods for Preventing Migraines The present invention relates to compositions and methods for preventing migraines. The migraine prophylaxis composition is a single dosage form comprising at least one form of elemental magnesium and at least one NSAID. The prophylaxis composition, comprising at least ... | 06/23/2011 |
| 20110130390 | Use of COX-2 Inhibitors for the Treatment of Schizophrenia, Delusional Disorders, Affective Disorders, Autism or Tic Disorders The invention concerns the use of a COX-2 inhibitor for the treatment of psychiatric disorders such as schizophrenia, delusional disorders, affective disorders, autism or tic disorders, in particular chronic schizophrenic psychoses and schizoaffective psychoses, tempora... | 06/02/2011 |
| 20110123470 | NATURAL BIOACTIVE COMPOUNDS The present invention relates to butenolide compounds having cytoprotection such as antioxidant, anti-inflammatory and/or antifungal properties, and which are derived from the marine fungus Aureobasidium. ... | 05/26/2011 |
| 20110118243 | ANTI-INFLAMMATORY DRUG DELIVERY SYSTEM The invention provides dosage forms for the delivery of one or more non-steroidal anti-inflammatory drugs to equines. The dosage forms are palatable, desirable, and easy to administer with little or no mess or waste. The dosage form can be a cookie that includes one or ... | 05/19/2011 |
| 20110098351 | Lactone compounds which can be used as antioxidant agents in pharmaceutical, cosmetic or food compositions and their method of preparation The subject of the present invention is specific lactone compounds which can be used as antioxidant agents in pharmaceutical or cosmetic compositions or in food products, the said compounds containing a naphthalene ring onto which two lactone units are grafte.... | 04/28/2011 |
| 20110098323 | INHIBITORS OF BACTERIAL BIOFILM FORMATION Organic compounds are described for use in inhibiting or preventing formation of bacterial biofilms.... | 04/28/2011 |
| 20110091574 | TREATMENT OF ADENOCARCINOMA EXPRESSING LKB1 WITH MTOR INHIBITOR IN COMBINATION WITH COX2 INHIBITOR Methods of treating adenocarcinoma cells such as NSCLC cells are disclosed that depend upon the level of functionally active LKB1 expressed in the cancer cells being treated. In one embodiment, the cancer cells express functionally active LKB1 and the method comprises c... | 04/21/2011 |
| 20110092588 | LACTONE FORMULATIONS AND METHOD OF USE Compounds of Formulae Ia and Ic having a lactone structure and an methylene group at the alpha-position of the lactone structure and methods for using and making the compounds have been disclosed. The lactone compounds can be reacted with an neucleaphilic agent to open ... | 04/21/2011 |
| 20110092368 | 2,4,6-Phenyl-substituted cyclic ketoenols The present invention relates to novel 2,4,6-phenyl-substituted cyclic ketoenols of the formula (I)
| |
| 20110092587 | Branched-chain amino acid composition for improving skeletal muscle protein metabolism The present invention relates to compositions and methods for improving skeletal muscle protein metabolism through encouraging skeletal muscle protein synthesis, reducing skeletal muscle protein degradation, and attenuating inflammatory signaling in exercising muscle.... | 04/21/2011 |
