Bizarre Patents
A new toilet tank assembly aquarium for housing aquatic creatures.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Application No. | Application Title | Issue Date |
| 20120128693 | CADHERIN-11 INHIBITORS AND METHODS OF USE THEREOF Cadherin-11 inhibitors and methods for the prevention and treatment of cadherin-11 related diseases are described herein. Cadherin-11 related diseases include cancer and rheumatoid arthritis.... | 05/24/2012 |
| 20120107323 | KINASE PROTEIN BINDING INHIBITORS The invention provides compounds capable of treating a subject suffering from or being susceptible to a cell proliferative disorder (especially, cancer), methods of identifying and using the compounds, pharmaceutical compositions and kits thereof.... | 05/03/2012 |
| 20120107300 | Cannabinoid Compositions and Methods Cannabinoid compositions and methods of administering said cannabinoid compositions are disclosed. The cannabinoid compositions disclosed herein include compounds which have been strategically selected to eliminate, or least mitigate, one of the negative side effects as... | 05/03/2012 |
| 20120083488 | TETRACYCLIC COMPOUND A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or c... | 04/05/2012 |
| 20120083526 | SYNTHESIS OF 1-(2,3-DIHYDROBENZOFURAN-4-YL)ETHANONE AS INTERMEDIATE IN THE PREPARATION OF RAMELTEON The present invention relates in general to the field of organic chemistry and in particular to the preparation of 1-(2,3-dihydrobenzofuran-4-yl)ethanone, an intermediate in preparation of (S)—N-[2-(1,6,7,8-tetrahydro-2H-indeno-[5,4-b]furan-8-yl)ethyl]propionamide, i.... | 04/05/2012 |
| 20120083527 | Anticancer Agents The present disclosure relates generally to compositions and methods for treating cancer. In some aspects, novel spirohexenolides and methods of using and producing them are described.... | 04/05/2012 |
| 20120071523 | BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS The instant invention provides novel benzofuran-4,5-diones and pharmaceutical compositions thereof useful for inhibiting PDF and for treating proliferative and infectious diseases. Compounds may be selective for eukaryotic (e.g., human) PDF or prokaryotic PDF.... | 03/22/2012 |
| 20120071539 | COMPOUNDS AND METHODS FOR MODULATING THE SILENCING OF A POLYNUCLEOTIDE OF INTEREST Methods and compositions comprising chemical compounds that modulate the silencing of a polynucleotide of interest in a cell are provided. Such chemical compounds when used in combination with an appropriate silencing element can be used to modulate (increase or decreas... | 03/22/2012 |
| 20120045519 | USE OF DEOXYELEPHANTOPIN (DET) AND ANALOGUES THEREOF FOR TREATMENT OF MELANOMA Methods for treating melanoma in a subject in need thereof are disclosed. The method comprises administering to the subject a composition comprising a therapeutically effective amount of deoxyelephantopin or an analogue thereof; and a pharmaceutically acceptable carrier... | 02/23/2012 |
| 20120046242 | MOLECULAR ACTIVATORS OF THE WNT/BETA-CATENIN PATHWAY The present invention is directed toward a method of treating a subject for a condition mediated by aberrant Wnt/β-catenin signaling by selecting a subject with a condition mediated by aberrant Wnt/β-catenin signaling and administering to the selected subject a compou... | 02/23/2012 |
| 20120040956 | INHIBITORS OF HIF-1 PROTEIN ACCUMULATION The invention relates to cyclopentabenzofuran derivatives for the treatment and/or prophylaxis of angiogenesis-related disorders.... | 02/16/2012 |
| 20120035170 | NOVEL UNSATURATED TETRACYCLIC TETRAHYDROFURAN DERIVATIVES This invention concerns novel substituted unsaturated tetracyclic tetrahydrofuran derivatives with binding affinities towards serotonine receptors, in particular 5-HT2A and 5-HT2C receptors, and towards dopamine receptors, in particular dopamine D2... | 02/09/2012 |
| 20120028892 | INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE AND METHODS OF USE THEREOF The invention is directed to a compound according to formula (I). The compounds of formula (I) include prodrugs, pharmaceutically acceptable salts, stereoisomer mixtures, and enantiomers thereof. The invention is also directed to a pharmaceutical composition comprising ... | 02/02/2012 |
| 20120022153 | TRICYCLIC CONDENSED HETEROCYCLIC COMPOUND, PROCESS OF PRODUCING SAME, AND USE THEREOF A novel compound derived from the culture product of an actinomycete and having an antitumor activity is provided. Provided is a compound represented by any one of formulas (I), (II) and (III) or an optical i... | 01/26/2012 |
| 20120020954 | METHODS OF PREDICTING CLINICAL COURSE AND TREATING MULTIPLE SCLEROSIS Provided are methods and kits for classifying a subject as being more likely to have benign multiple sclerosis (BMS) or as being more likely to have typical relapsing remitting multiple sclerosis (RRMS). Classification of multiple sclerosis disease course is performed b... | 01/26/2012 |
| 20110319389 | METHODS AND COMPOSITIONS FOR TREATING FATIGUE ASSOCIATED WITH DISORDERED SLEEP USING VERY LOW DOSE CYCLOBENZAPRINE The present invention relates to methods for the treatment or prevention of fatigue associated with disordered sleep, for example, in multiple sclerosis, fibromyalgia, Fabry's disease, Parkinson's disease, or traumatic brain injury, using cyclobenzaprine The present inv... | 12/29/2011 |
| 20110319485 | Composition Having Anti-Helicobacter Pylori Activity And Its Application To Inhibit Helicobacter Pylori The present invention provides a composition having anti-Helicobacter pylori activity and the composition contains ovatodiolide with effective dosage to inhibit Helicobacter pylori growth or ovatodiolide related substances and its acceptable carrier. The p... | 12/29/2011 |
| 20110312903 | FLUORINATION OF ORGANIC COMPOUNDS Methods for fluorinating organic compounds are described herein.... | 12/22/2011 |
| 20110301233 | Novel Polyisoprenylated Benzophenone Derivatives from Garcinia paucinervis Novel polyisoprenylated benzophenone derivatives isolated from the plant Garcinia paucinervis. Among these new compounds, paucinones A-C (Compounds 1-3) contains an unexpected cyclohexane-spiro-tetrahydrofuran moiety. A 1-methylene-3,3-dimethylcyclohexane group n... | 12/08/2011 |
| 20110288166 | TRIPTOLIDE C-RING DERIVATIVES AS ANTICANCER AGENTS AND IMMUNE MODULATORS Disclosed are compounds based on C- and D-ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.... | 11/24/2011 |
| 20110263700 | ANTROCIN CONTAINING PHARMACEUTICAL COMPOSITIONS FOR INHIBITING CANCER CELLS This subject invention is directed to a pharmaceutical composition for the inhibition of cancer cells, comprising an effective amount of a compound of formula I (Sesquiterpene lactones, antrocin) or pharmaceutically acceptable salts thereof, together with a pharmaceutic... | 10/27/2011 |
| 20110250166 | COMBINATION OF ROCAGLAMIDE AND APOPTOSIS INDUCING SUBSTANCES FOR THE TREATMENT OF CANCER The present invention relates to a combined preparation comprising at least one rocaglamide derivative and at least one apoptosis inducing agent, preferably from the group of substances comprising agents inducing the extrinsic apoptotic pathway, antiproliferative agents... | 10/13/2011 |
| 20110251216 | COMPOSITIONS AND METHODS FOR INHIBITING EZH2 The present invention relates to therapeutic targets for cancer. In particular, the present invention relates to small molecules and nucleic acids that target EZH2 expression in cancer (e.g., prostate cancer, breast cancer, other solid tumors, multiple myeloma).... | 10/13/2011 |
| 20110251236 | GALACTOKINASE INHIBITORS Therapeutic agents for treatment of Galactosemia and disorders thereof, and other enzyme related disorders thereof are identified. The compounds inhibit galactokinase (GALK) and other kinase activity and are identified by a high throughput screening assay.... | 10/13/2011 |
| 20110245206 | ANTIOXIDANT INFLAMMATION MODULATORS: C-17 HOMOLOGATED OLEANOLIC ACID DERIVATIVES This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles ... | 10/06/2011 |
| 20110229464 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING AGE-RELATED MACULAR DEGENERATION WITH MELATONIN ANALOGUES Pharmaceutical compositions and methods for treating and/or preventing age-related macular degeneration with melatonin analogues are provided.... | 09/22/2011 |
| 20110224146 | AUGMENTED COGNITIVE TRAINING The present invention provides methods of therapy of cognitive deficits associated with a central nervous system disorder or condition, methods of enhancing cognitive performance and methods for repeated stimulation of neuronal activity or a pattern of neuronal activity... | 09/15/2011 |
| 20110224293 | USE OF DRONEDARONE FOR THE PREPARATION OF A MEDICAMENT FOR USE IN THE PREVENTION OF CARDIOVASCULAR HOSPITALIZATION OR OF MORTALITY Methods of using dronedarone or a pharmaceutically acceptable salt thereof, for the preparation of a medicament for use in the prevention of cardiovascular hospitalization or of mortality, articles of manufacture and packages related thereto.... | 09/15/2011 |
| 20110218143 | COMPOSITIONS AND METHODS FOR TISSUE REPAIR The invention generally provides compositions and methods for the repair or regeneration of a tissue or organ in need thereof.... | 09/08/2011 |
| 20110217301 | METHODS FOR TREATING OR SCREENING FOR COMPOUNDS FOR THE TREATMENT OF SEPSIS The present invention relates to a method for treating and screening for compounds for the treatment of sepsis. More specifically, the treatment and screening methods are based on the discovery that granzyme B containing platelets (GzmB-platelet) causes apoptosis by dir... | 09/08/2011 |
| 20110184058 | SYNTHESIS OF 6,7-DIHYDRO-1H-INDENO[5, 4-B] FURAN-8(2H)-ONE AS INTERMEDIATE IN THE PREPARATION OF REMELTEON The present invention describes the preparation of 6,7-dihydro-1H-indeno[5,4-b]furan-8(2H)-one, a key intermediate in preparation of ramelteon. The present invention also describes further preceding intermediate compounds useful for the synthesis of 6,7-dihydro-1H-inden... | 07/28/2011 |
| 20110178065 | NOVEL CYP17 INHIBITORS Provided herein are inhibitors of CYP17 enzyme. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat androgen-dependent diseases, disor... | 07/21/2011 |
| 20110177085 | Bitter Taste Receptors The present invention relates to bitter-taste receptors and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block, bitter taste transduction, or enhance bitter taste response.... | 07/21/2011 |
| 20110150971 | ABUSE RESISTANT DRUGS, METHOD OF USE AND METHOD OF MAKING An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprise... | 06/23/2011 |
| 20110150970 | ABUSE RESISTANT DRUGS, METHOD OF USE AND METHOD OF MAKING An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprise... | 06/23/2011 |
| 20110144043 | Stat modulators The present invention is directed to methods, kits and compositions for modulating the activity of Stat molecules (e.g., Stat1, Stat3 and Stat5). The compounds of the invention are useful for treating and/or preventing disorders characterized by Stat dysregulation, such... | 06/16/2011 |
| 20110136752 | NOVEL ANTIBIOTICS The invention relates generally to novel antibiotics and their analogs, to processes for the preparation of these novel antibiotics, to pharmaceutical compositions comprising the novel antibiotics; and to methods of using the novel antibiotics to treat or inhibit variou... | 06/09/2011 |
| 20110130452 | STORE-OPERATED CALCIUM CELLULAR ASSAY The present technology provides a cell based assay for identifying compounds that modulate store-operated ionic calcium levels using itpr mutant cell lines, such as itpr-ku cells, which have abnormal ionic calcium levels.... | 06/02/2011 |
| 20110112180 | NOVEL STAT3 PATHWAY INHIBITORS AND CANCER STEM CELL INHIBITORS The present invention relates to a novel naphtho class of compounds as Stat3 pathway inhibitors and as cancer stem cell inhibitors; to methods of using such compounds to treat cancer; to methods of using such compounds to treat disorders in a mammal related to aberrent ... | 05/12/2011 |
| 20110104146 | ANTITHROMBOTIC AGENTS AND METHODS OF USE THEREOF The instant invention provides methods and compositions for the treatment, prevention and diagnosis of for example, platelet aggregation or clot formation in a subject. The invention inhibits the activity of decreases the amount of neutrophils in the subject by inhibiti... | 05/05/2011 |
