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| Application No. | Application Title | Issue Date |
| 20120129818 | Compositions and Methods for Treatment of Cardiovascular Disease Ortho methoxy phenolic compounds are provided that include methylenedioxyphenyl ferulate and ferulylproline and derivatives thereof. Pharmaceutical compositions comprising the compounds and methods of using the compounds for treating cardiovascular diseases, including h... | 05/24/2012 |
| 20120129833 | CYCLIC KETOENOLS FOR THERAPY The invention relates to 5′-biphenyl-substituted cyclic ketoenols for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of diabetes, obesity, hyperlipidaemia, fatty livers and of disorders o... | 05/24/2012 |
| 20120046264 | COMMERCIAL SCALE PRODUCTION METHODS FOR TRANSDERMAL HORMONE FORMULATIONS Methods for commercial production of transdermal formulations comprising a hormone compound are provided. In particular, methods for commercial scale production under an inert atmosphere of a transdermal formulation comprising a therapeutically effective amount of a hor... | 02/23/2012 |
| 20120035200 | GRISEOFULVIN ANALOGUES FOR THE TREATMENT OF CANCER BY INHIBITION OF CENTROSOMAL CLUSTERING The invention relates to compounds of the formula (I), where the symbols have the meaning given in the specification, for use in a method for treating cancer, to use of these compounds for the manufacture of a pharmaceutical composition for the treatment of cancer, and ... | 02/09/2012 |
| 20120015910 | Synergistic fungicidal active substance combinations Novel active compound combinations comprising a carboxamide of the general formula (I) (group 1) in which
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| 20120010227 | FORMULATION FOR NAIL AND NAIL BED DISEASES The invention relates to a pharmaceutical composition with a content in active ingredient that can be an antimycotic, so that the composition is suitable for the treatment of onychomycoses, in particular severe onychomycoses. The inventive formulation is an ointment-lik... | 01/12/2012 |
| 20120010281 | ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS Infections caused by Mycobacterium tuberculosis kill more than 1.8 million people each year. While the persistence of this pathogenic bacterial species and the emergence of multidrug resistant strains have created an urgent need for new TB therapies, a new TB-spe... | 01/12/2012 |
| 20110312904 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES The present invention provides compounds of Formula (I), compositions comprising an effective amount of a compound of Formula (I), optionally with chemotherapeutic drugs such as a tubulin-binding drug, and methods of their use for reducing the toxicity of cytotoxic agen... | 12/22/2011 |
| 20110313003 | GPR120 RECEPTOR AGONISTS AND USES THEREOF GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.... | 12/22/2011 |
| 20110306499 | Biphenyl-Substituted Spirocyclic Ketoenols The invention relates to novel compounds of the formula (I)
| 12/15/2011 |
| 20110306662 | Steroid-Derived Cyclopamine Analogs and Methods for Using the Same in the Prevention or Treatment of Cancer The present invention relates to steroid-derived cyclopamine analogs and methods for using the same for inhibiting sonic hedgehog signaling and preventing or treating cancer. A method for synthesizing the analogs of the present invention from a steroid is also provided.... | 12/15/2011 |
| 20110301099 | Method for enhancing penetration of lipid insoluble medicaments through cell membranes using small S-Allyl-containing molecules with phospholipid permeability as carrier molecules A method and composition that allows for the penetration of lipid insoluble medicaments through cell membranes using small S-Allyl-containing molecules with phospholipid permeable molecules as carrier molecules. S-Allyl-containing compounds can include alliin, allicin, ... | 12/08/2011 |
| 20110301233 | Novel Polyisoprenylated Benzophenone Derivatives from Garcinia paucinervis Novel polyisoprenylated benzophenone derivatives isolated from the plant Garcinia paucinervis. Among these new compounds, paucinones A-C (Compounds 1-3) contains an unexpected cyclohexane-spiro-tetrahydrofuran moiety. A 1-methylene-3,3-dimethylcyclohexane group n... | 12/08/2011 |
| 20110294783 | Insecticidal Compositions Having Improved Effect The present invention concerns boosting the activity of crop protection materials comprising inhibitors of fatty acid biosynthesis (for example phenyl-substituted cyclic ketoenols) through the addition of ammonium salts and/or phosphonium salts or through the addition o... | 12/01/2011 |
| 20110280921 | ANTIBACTERIAL HYDROGEL AND USE THEREOF IN ORTHOPEDICS The present invention relates to hydrogels endowed with antibacterial properties, to be used for injection in damaged bones or in the production of antibacterial coatings of prostheses for implant in the human or animal body, obtained by loading with antibacterial agent... | 11/17/2011 |
| 20110275708 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO The invention relates to a novel compound of formula I or pharmaceutically acceptable salts thereof as well as pharmaceutical, nutraceutical, and botanical drug compositions and therapeutic methods related thereto. In certain embodiments, the compounds are used for the ... | 11/10/2011 |
| 20110275709 | TELLURIUM-CONTAINING COMPOUNDS FOR AFFECTING MALE'S FERTILITY FOLLOWING CHEMOTHERAPY AND/OR RADIOTHERAPY Use of tellurium-containing compounds for maintaining and/or augmenting fertility in a male subject following chemotherapy and/or radiotherapy is disclosed. The tellurium-containing compound is utilized in combination with a chemotherapeutic agent and/or radiation, such... | 11/10/2011 |
| 20110263424 | Oxaspirocyclic Spiro-Substituted Tetramic Acid and Tetronic Acid Derivatives The present invention relates to novel oxaspirocyclic spirophenyl-substituted tetramic acid and tetronic acid derivatives of the formula (I)
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| 20110251146 | TOPICAL ANTIFUNGAL COMPOSITION A topical, foamable composition is provided that includes at least one antifungal agent that is able to penetrate the upper layers of skin and is retained in or on an area to be treated for a prolonged period of time, and that has a residual non-volatile component conte... | 10/13/2011 |
| 20110201661 | Spiro Derivatives of Parthenin as Novel Anticancer Agents The present invention relates to novel spiro derivatives of parthenin prepared by the dipolar cycloaddition of various dipoles viz, benzonitrile oxides, nitrones, azides, nitrile ylide diazoalkane, nitrile imide, ozone, azomethine imides, azomethine ylides etc. with exo... | 08/18/2011 |
| 20110195842 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols The invention relates to novel 2,4,6-phenyl-substituted cyclic ketoenols of the formula (I), in which
| 08/11/2011 |
| 20110178170 | GRISEOFULVIN ANALOGUES FOR THE TREATMENT OF CANCER BY INHIBITION OF CENTROSOMAL CLUSTERING The present invention relates to uses of compounds having a structure as shown by formula (I) for the manufacture of a pharmaceutical composition for the treatment of cancer. Moreover, the present invention encompasses methods of treatment for said diseases. 07/21/2011 | |
| 20110165259 | COMPOSITE ORGANIC COMPOUND POWDER FOR MEDICAL USE, METHOD FOR PRODUCING SAME AND SUSPENSION OF SAME [Problem to be Solved] The purpose of present invention is to provide a medicine which has low contamination with a fine-pulverizing medium, is safe and has improved bioavailability. [Solution] A method for producing a composite organic com... | 07/07/2011 |
| 20110143943 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS The present invention relates to novel C2-phenyl-substituted cyclic ketoenols of the formula (I) in which W, X, Y, Z and CKE are as defined in the description, to proc... | 06/16/2011 |
| 20110124656 | Methods and Compositions for Treating Symptoms Associated with Post-Traumatic Stress Disorder using Cyclobenzaprine The present invention relates to methods for the treatment or prevention of symptoms associated with post-traumatic stress disorder, and related pharmaceutical compositions. Of particular interest are pharmaceutical compositions comprising a very low dose of cyclobenzap... | 05/26/2011 |
| 20110124502 | PEST CONTROL COMPOSITIONS AND METHODS Embodiments of the present invention provide compositions for controlling a target pest including a first agent and a second agent comprising a pest control product or a signal cascade modulator, wherein the first agent and the second agent act synergistically to contro... | 05/26/2011 |
| 20110112112 | APOGOSSYPOLONE DERIVATIVES AS ANTICANCER AGENTS The disclosure provides compounds and methods of using Apogossypolone derivatives for treating diseases and disorders. In particular, the disclosure provides compounds of Formula I: or a pharmaceutically acce... | 05/12/2011 |
| 20110104235 | COMPOSITIONS AND METHODS FOR TREATING CONDITIONS OF THE NAIL UNIT The biodegradable drug delivery systems described here are formulated for implantation into the nail unit and its surrounding tissues for the treatment of various nail unit conditions. The systems include non-temperature dependent phase change compositions that may be f... | 05/05/2011 |
| 20110071220 | Use of Tetronic Acid Derivatives for Fighting Insects and Red Spider Mites by Watering on the Ground, Droplet Application or Immersion Application Compounds of the formula (II) in which A, B, G, W, X, Y and Z may have the meanings given in the description are highly suitable for controlling animal pests such as insects and/or spider mites by treating th... | 03/24/2011 |
| 20110065766 | METHODS OF USE OF ANTIVIRAL COMPOUNDS The present invention relates, in part, to methods of treatment, prevention, and inhibition of viral disorders. In one aspect, the present invention relates to inhibition of the M2 proton channel of influenza viruses (e.g. influenza A virus) and other similar viroporins... | 03/17/2011 |
| 20110059175 | ENHANCING SOLUBILITY AND DISSOLUTION RATE OF POORLY SOLUBLE DRUGS The present invention relates generally to use of a polyvinyl alcohol-polyethylene glycol graft copolymer (PVA-PEG graft co-polymer), such as Kollicoat IR, in the formulation of solid dispersions of low aqueous solubility and dissolution rate bioactive compound and, mor... | 03/10/2011 |
| 20110059907 | Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care This invention relates to certain complexes of ascorbic acid and its derivatives with certain natural antioxidant and anti-inflammatory ketones for topical or oral application; said complexes having general chemical formula (I), its isomers, and salts thereof, including... | 03/10/2011 |
| 20110053883 | AGENT THAT MODULATES PHYSIOLOGICAL CONDITION OF PESTS, INVOLVED IN INSECT C-JUN AMINO-TERMINAL KINASE ACTIVITY The present invention provides an agent that modulates physiological condition of pests, wherein the agent has an ability to modulate the activity of an insect c-Jun NH2-terminal kinase; a method for assaying pesticidal activity of a test substance, which com... | 03/03/2011 |
| 20110039701 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives The invention relates to novel compounds of the formula (I) in which X, Y, Z, A, B and G have the meanings given above, | 02/17/2011 |
| 20110039700 | Method for Improved Utilization of the Production Potential of Transgenic Plants Introduction The Invention discloses novel uses and methods for TSD directed to increasing the production potential of transgenic plants as well as methods for controlling unwanted animal pests on transgenic plants by application of the compounds to the transgenic plants or to propa... | 02/17/2011 |
| 20110021625 | NEURONAL CELL DEATH INHIBITOR There is provided a neuronal cell death inhibitor having a high efficacy. A neuronal cell death inhibitor comprising a compound of general formula (1) below: (where R1 is a hydrogen atom or an opti... | 01/27/2011 |
| 20110021624 | Alpha-Amino-N-Substituted Amides, Pharmaceutical Composition Containing Them and Uses Thereof Disclosed are a series of α-amino-N-substituted amide compounds having a structure of the following formula, the pharmaceutically acceptable salts thereof, and the pharmaceutical composition comprising the same. The α-amino-N-substituted amide compounds or the pharmac... | 01/27/2011 |
| 20110021549 | SUBSTITUTED BENZOFUSED DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS The present invention relates to substituted benzofused derivatives, which can he used as vanilloid receptor ligands, method of treating diseases, conditions and/or disorders modulated by vanilloid receptors with them, and processes for preparing them. 01/27/2011 | |
| 20100330212 | SKIN SENSITIZER DELIVERY SYSTEM A skin-sensitizing formulation is provided in an edible, softgel pill. A person engaged in a sexual activity bites down on the pill, thereby effectuating the oral release of the skin-sensitizing formulation. This allows the skin-sensitizing formulation to be spread to a... | 12/30/2010 |
| 20100297256 | METHODS AND COMPOSITIONS FOR INHIBITING INTEGRINS USING TELLURIUM-CONTAINING COMPOUNDS Compositions and methods for inhibiting integrin and treating integrin-related conditions, utilizing tellurium-containing compounds, are disclosed. The tellurium-containing compounds comprise at least one tellurium dioxo moiety and may have any one of Formulae I to IV a... | 11/25/2010 |
