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Class 514/459 - Nitrogen containing


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter which contains nitrogen.
No. of applications: 230
Last issue date: 03/22/2012


1            
Application No.Application TitleIssue Date
20120070417ANTI-INFLUENZA FORMULATIONS AND METHODS
The invention relates to pharmaceutical compositions that contain a calcium salt as an active ingredient and also comprise another anti-influenza agent, and to methods for treating or preventing influenza virus infection.

...

03/22/2012
20120046355INHIBITORS OF SIALIDASE OR SIALIDASE-LIKE ENZYMES
The present invention describes compounds of Formula I or a pharmaceutically acceptable salts or derivatives thereof. Compositions comprising compounds of Formula I are also described. The present invention further relates to a method of producing non-2-enonate compound...
02/23/2012
20120046331Antifungal Agents and Uses Thereof
This invention relates to new antifungal agents, compositions thereof, and methods for inhibiting the growth of fungi involved in infection and disease of keratinized tissue, such as onychomycosis. The invention also relates to new antifungal agents, compositions thereo...
02/23/2012
20120041038AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions....
02/16/2012
20120041011SUBSTITUTED BENZOFUSED DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS
The present invention relates to substituted benzofused derivatives, which can he used as vanilloid receptor ligands, method of treating diseases, conditions and/or disorders modulated by vanilloid receptors with them, and processes for preparing them....
02/16/2012
20120041036SUBSTITUTED ACYLGUANIDINE DERIVATIVES (AS AMENDED)
An object of the present invention is to provide an excellent agent for treating or preventing dementia, schizophrenia based on serotonin 5-HT5A receptor modulating action.

It was discovered that acylguanidine derivatives, in whi...

02/16/2012
20120041039AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions....
02/16/2012
20120035255DERIVATIVE OF [(3-HYDROXY-4 PYRON-2-YL)-METHYL]-AMINE AND USE THEREOF AS ANTI-NEOPLASTIC DRUGS
The present invention relates to compounds having general formula (I), i.e. poly-alkyl-bis-maltolic molecules and in particular to derivates of [(3-hydroxy-4-pyron-2-yl)methyl]-amine and pharmaceutically acceptable salts thereof, and to the use thereof as anti-neoplasti...
02/09/2012
20120035179MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
The present invention provides compounds of Formula I useful as modulators of ABC transporter activity,

or a pharmaceutically acceptable salt thereof, wherein RB, n, B, RC, RD...

02/09/2012
20120022039NOVEL SUBSTITUTED INDANES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS DRUGS
The invention relates to substituted indanes and derivatives thereof, to physiologically acceptable salts and physiologically functional derivatives thereof, to the production thereof, to drugs containing at least one substituted indane according to the invention or der...
01/26/2012
20120022100ORGANIC COMPOUNDS
Disclosed are δ-amino-γ-hydroxy-ω-aryl-alkanoic acid amide compounds of formula (I)

and the salts thereof, having renin-inhibiting properties. Also disclosed are pharmaceutical compositions comprising thes...

01/26/2012
20120015936SUBSTITUTED TETRAHYDRONAPHTHALENES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS DRUGS
The invention relates to substituted tetrahydronaphthalenes, to derivatives thereof, to physiologically acceptable salts thereof, to physiologically functional derivatives, to the production thereof, to drugs containing at least one substituted tetrahydronaphthalene acc...
01/19/2012
20120015942SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF
This invention provides compounds of formula (I):

    • wherein R1a, R1b...
01/19/2012
20120016018COMPOSITION FOR INDUCING MULTIPLE NUCLEAR DIVISION OF CELLS
The present invention relates to the novel use of a composition comprising a compound of the formula I:

    • 01/19/2012
20120014898COMPOSITION FOR PREVENTING HAIR LOSS AND STIMULATING HAIR GROWTH
The present invention relates to the use of a composition comprising a compound of the formula I:

01/19/2012
20120016019PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER
The present invention relates to a compound of the formula I:

    • wherein R is C2...
01/19/2012
20120016017PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER
The present invention relates to a compound of the formula I:

    • wherein R is C2...
01/19/2012
20120010161NOVEL AZAPEPTIDE OR AZAPEPTIDOMIMETIC COMPOUNDS INHIBITING BCRP AND/OR P-GP
The present invention relates to compounds of azapeptide or azapeptidomimetic type of formula (I):

in which R1, R2, R3, X1, X2, X3, X4

01/12/2012
20120010227FORMULATION FOR NAIL AND NAIL BED DISEASES
The invention relates to a pharmaceutical composition with a content in active ingredient that can be an antimycotic, so that the composition is suitable for the treatment of onychomycoses, in particular severe onychomycoses. The inventive formulation is an ointment-lik...
01/12/2012
20120003306Pharmaceutical composition of nanoparticles for protein drug delivery
The invention discloses a pharmaceutical composition of bioactive nanoparticles composed of chitosan, poly-glutamic acid, and a bioactive agent for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability...
01/05/2012
20120004298OPHTHALMIC DEVICES CONTAINING CHEMOKINE ANTAGONISTS
Ionic ophthalmic devices, methods of treating chemoattractant cytokine receptor 2 (CCR2) mediated inflammatory conditions, and methods of making such devices are disclosed herein....
01/05/2012
20120004269Alkynyl Phenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders
Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions....
01/05/2012
20110306621ACYLGUANIDINE DERIVATIVES
An object of the present invention is to provide an excellent agent for treating or preventing dementia, schizophrenia based on a serotonin 5-HT5A receptor modulating action.

It was confirmed that acylguanidine derivatives, which...

12/15/2011
20110306542NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS
Compounds that bind the glucagon-like peptide 1 receptor (GLP-1) receptor are provided including compounds which are modulators of the GLP-1 receptors and compounds which are capable of inducing a stabilizing effect on the receptor for use in structural analyses of the ...
12/15/2011
20110294830NITROGEN-CONTAINING COMPOUNDS AND HARMFUL ORGANISM CONTROL AGENTS
The present invention provides a nitrogen-containing compound represented by formula (I1) (in formula (I1), R0 represents a nitro group or the like, Z represents an optionally substituted aryl group or the like, R3 represents ...
12/01/2011
20110280813NEURAMINIDASE INHIBITORS AND USES THEREOF
The invention is related to various methods for inhibiting or reducing biofilm formation, treating a biofilm production-related disorder, preventing biofilm formation, and screening for neuraminidase inhibitors....
11/17/2011
20110281879SULFONYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS
The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositi...
11/17/2011
20110263556New Compounds
This invention relates to compounds of formula I,

their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medi...

10/27/2011
20110263580METHOD FOR TREATING ALZHEIMER'S DISEASE AND RELATED CONDITIONS
This invention relates to a method for treating or preventing diseases associated with the deposition of β-amyloid peptide in the brain, such as Alzheimer's disease, said method involving administration of a gamma-secretase inhibitor in an intermittent dosing regime to...
10/27/2011
201102636991-Phenyl-2-DimethylaminomethylCyclohexane Compounds and Therapies for Depressive Symptoms, Pain and Incontinence
Metabolites of [2-(3-methoxyphenyl)-cyclohexylmethyl]dimethylamine as free bases and/or in the form of physiologically acceptable salts, corresponding medicaments, the use of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine and the metabolites thereof for producing ...
10/27/2011
20110262356Active Particles for Bio-Analytical Applications and Methods for Preparation Thereof
Luminescent and/or electroactive nanoparticles suitable for MRI (Magnetic Resonance Imaging) and/or PET (Positron Emission Tomography) are prepared by mixing luminescent or electroactive compounds and ethyl oxide/propyl oxide block-copolymers in an organic solvent, whic...
10/27/2011
20110256188DRY POWDER PHARMACEUTICAL COMPOSITION FOR INHALATION
There is provided a dry powder pharmaceutical composition for inhalation useful for preventing and/or treating influenza virus infections contains as a medicinal component a compound represented by formula (I):

10/20/2011

20110257226HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF
There is provided a halogen-containing organosulfur compound having a controlling effect on arthropod pests represented by the formula (I): wherein m represents 0, 1 or 2; n represents 0, 1 or 2; A represents an optionally substituted 3- to 8-membered saturated heterocy...
10/20/2011
20110243914SHIGA TOXIN B-SUBUNIT AS A VECTOR FOR TUMOR DIAGNOSIS AND DRUG DELIVERY TO GB3 EXPRESSING TUMORS
The invention relates to new compounds for cancer therapy or diagnosis and more specifically to the use of a non-toxic B subunit of Shiga toxin mutant as a vector for diagnostic products or drugs in over-expressing Gb3 receptor cells, such compounds having th...
10/06/2011
20110245335NEW INHIBITORS FOR TREATING DISEASES ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN
The present invention relates in general to a compound which is characterized by a formula selected from the following formulas A, B, C, D, E or F; or a pharmaceutically acceptable salt thereof. The present invention further relates to pharmaceutical composition compris...
10/06/2011
20110230346Biphenyl-Substituted Cyclic Ketoenols
The invention relates to novel compounds of the formula (I)

  • in which W, X, Y, Z, and CKE have the meanings given above,
  • to a pl...
09/22/2011
20110230452Compounds and methods for the treatment of pain and other diseases
The present invention relates generally to pharmaceutical agents, and in particular, to metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of dual acting MMP-2 and MMP-9 inhibiting compounds that exhibit increased potency,...
09/22/2011
20110229437Method of Treating Asthma with Antiviral Agents
The present invention provides a method of treating asthma by administering a therapeutically effective amount of an antiviral agent to a patient. The antiviral agent may be a neuraminidase inhibitor, a viral fusion inhibitor, a protease inhibitor, a DNA polymerase inhi...
09/22/2011
20110212056COMBINATION THERAPY FOR THE TREATMENT OF LIVER DISEASES
Provided herein are methods for treatment of a liver disease by administering a combination of a matrix metalloproteinase inhibitor and a caspase inhibitor. Also provided are methods for reducing liver damage associated with a liver disease by administering the MMP and ...
09/01/2011
20110207604ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM
A species of Burkholderia sp with no known pathogenicity to vertebrates but with pesticidal activity (e.g., plants, insects, fungi, weeds and nematodes) is provided. Also provided are natural products derived from a culture of said species and methods of controll...
08/25/2011
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