Did You Know...
...that power steering was invented by independent inventor Francis W. Davis? As chief engineer in the 1920s of the truck division of the Pierce Arrow Motor Car Company, he saw how hard it was to steer heavy vehicles. So that he would be able to keep the profits from his future invention, Davis left his job, rented a small engineering shop in Waltham, Mass., and developed a hydraulic power steering system that led to power steering.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Application No. | Application Title | Issue Date |
| 20120083471 | Novel Compounds, Pharmaceutical Compositions Containing Same, Methods of Use for Same, and Methods for Preparing Same The present invention relates to novel pharmaceutical compositions containing the same, and methods of use for a variety of therapeutically valuable uses including, but not limited to, treating obesity by inhibiting the activity of Glycerol 3-phosphate acyltransferase (... | 04/05/2012 |
| 20120046350 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the tr... | 02/23/2012 |
| 20120046272 | Novel Therapeutic Compounds The present invention describes a series of therapeutically active compounds of formula I,
that are useful for treating a disorder in a mammal. In the f... | 02/23/2012 |
| 20120041039 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.... | 02/16/2012 |
| 20120041038 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.... | 02/16/2012 |
| 20120041046 | NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION The present invention concerns compounds of general Formula (I): method of preparation and uses thereof.... | 02/16/2012 |
| 20120029048 | PHENYLALKYL N-HYDROXYUREAS FOR TREATING LEUKOTRIENE RELATED PATHOLOGIES The method of treating patients by administering N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea for treatment of leukotriene related pathologies and compositions for this use.... | 02/02/2012 |
| 20120029013 | DERIVATIVES OF AMINOCYCLOBUTANE OR AMINOCYCLOBUTENE, THEIR METHOD OF PREPARATION AND THEIR USE AS MEDICAL PRODUCTS The present invention concerns compounds of general formula (1), where in:—-a- is a single or double bond, Ar is an aromatic group, substituted or unsubstituted, R1 and R2 each independently or together are: a hydrogen atom or C1-C6 alkyl group, ... | 02/02/2012 |
| 20120022080 | Plasminogen Activator Inhibitor-1 Inhibitor The present invention provides a novel compound having plasminogen activator inhibitor-1 inhibitory activity, and an inhibitor of PAI-1 comprising the compound as an active ingredient. The present invention also provides a pharmaceutical composition having an inhibitory... | 01/26/2012 |
| 20120015911 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.... | 01/19/2012 |
| 20120004262 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE The present invention relates to phenylcyclopropylamine derivatives. In particular, pharmaceutical compositions comprising phenylcyclopropylamine derivatives are provided. The compounds of this invention can, inter alia, be used for the treatment and the prevention of c... | 01/05/2012 |
| 20120004260 | INHIBITION OF FATTY ACID SYNTHESIS BY IODO-NITROBENZAMIDE COMPOUNDS AND METHODS OF TREATMENT THEREOF The present invention relates to a method of treating a fatty acid synthesis related disease comprising administering to a patient in need thereof an effective amount of a PARP inhibitor or metabolite thereof to inhibit fatty acid synthesis, wherein the fatty acid synth... | 01/05/2012 |
| 20120004269 | Alkynyl Phenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.... | 01/05/2012 |
| 20110312911 | GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE Glucagon receptor antagonist compounds are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.... | 12/22/2011 |
| 20110313032 | COMPETITIVE INHIBITORS OF TYPE II DEHYDROQUINASE ENZYME The present invention is directed to a compound of formula (I), its diastereoisomers, its enantiomers or its pharmaceutically acceptable salts or solvates, formula (I), to procedures of obtaining the same, to intermediates thereof, and use as competitive inhibitors of t... | 12/22/2011 |
| 20110306600 | NOVEL THERAPEUTIC COMPOUNDS The invention discloses a number of therapeutic compounds and a method of treating a disorder in mammal.... | 12/15/2011 |
| 20110306621 | ACYLGUANIDINE DERIVATIVES An object of the present invention is to provide an excellent agent for treating or preventing dementia, schizophrenia based on a serotonin 5-HT5A receptor modulating action. It was confirmed that acylguanidine derivatives, which... | 12/15/2011 |
| 20110281924 | NOVEL MICROBIOCIDES Compounds of formula (I), in which the substituents are as defined in claim 1, are suitable for use as microbiocides. ... | 11/17/2011 |
| 20110274750 | ENTERIC FORMULATION OF DULOXETINE AND ITS CORE AND PREPRATION METHOD An enteric formulation of duloxetine, its core and preparing method thereof are disclosed. The core comprises duloxetine or its salt and pharmaceutically acceptable excipients. The excipients include water-soluble hot melt materials selected from PEG, poloxamer, polyoxy... | 11/10/2011 |
| 20110268786 | PATCH PRODUCTION TECHNOLOGY The invention relates to a transdermal, especially dopaminergic patch, comprising a release liner film, an active substance layer, and a carrier film, wherein the active substance layer is applied between the release liner film and the carrier film. The release liner fi... | 11/03/2011 |
| 20110257226 | HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF There is provided a halogen-containing organosulfur compound having a controlling effect on arthropod pests represented by the formula (I): wherein m represents 0, 1 or 2; n represents 0, 1 or 2; A represents an optionally substituted 3- to 8-membered saturated heterocy... | 10/20/2011 |
| 20110257183 | BIS-ARYL SULFONAMIDES Compounds are provided that act as potent antagonists of chemokine receptors. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of chemokine receptor-mediated diseases, and as controls in as... | 10/20/2011 |
| 20110251175 | Stigmine Conjugates for Substance Use Disorders The invention relates to methods for the treatment or prevention of substance use disorders.... | 10/13/2011 |
| 20110251206 | Squaramide derivatives as CXCR2 antagonist The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases ... | 10/13/2011 |
| 20110245261 | ANTIPROLACTINIC VETERINARY COMPOSITION FOR RUMINANTS This present invention relates to an antiprolactinic veterinary composition to be administered to ruminants. Said composition comprises at least one antiprolactinic compound which is an agonist of dopamine receptors, and is particularly useful for promoting a substantia... | 10/06/2011 |
| 20110245264 | Modulators of G Protein-Coupled Receptor 88 The present disclosure is generally directed to compounds which can modulate G-protein coupled receptor 88, compositions comprising such compounds, and methods for modulating G-protein coupled receptor 88.... | 10/06/2011 |
| 20110230541 | PROCESS FOR THE PREPARATION OF ROTIGOTINE A process for the preparation of Rotigotine (I) and of pharmaceutically acceptable salts thereof, which comprises the reductive amination of an amine of formula 6 with the 2-thienylacetic acid-sodium boron hydride complex and which makes use of hydrobromide 5 as an inte... | 09/22/2011 |
| 20110223244 | ALCOHOL RESISTANT ENTERIC PHARMACEUTICAL COMPOSITIONS Pharmaceutical formulations that resist ethanol-induced dose dumping and methods of use thereof.... | 09/15/2011 |
| 20110224213 | Use of Glutaric Acid Derivatives or the Pharmaceutically Acceptable Salts Thereof as Anti-Arrhythmic Agents The invention relates to the use of glutaric acid derivatives of general formula (I), which are disclosed in the invention description, as anti-arrhythmic agents.... | 09/15/2011 |
| 20110218221 | NOVEL HISTONE DEACETYLASE INHIBITORS, PROCESS FOR PREPARATION AND USES THEREOF The present invention relates to compounds represented by formula (I) or composition comprising at least one of such compounds, which are inhibitors of histone deacetylase. The detailed description of these compounds is disclosed in the Description. These compounds and ... | 09/08/2011 |
| 20110196015 | N 1-2-THIOPHENE-2-YLETHYL-N2-SUBSTITUTED BIGUANIDE DERIVATE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENTS The present invention provides an N1-2-thiophen-2-ylethyl-N2-substituted biguanide derivative of formula (I) or a pharmaceutically acceptable salt thereof, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient. The inventi... | 08/11/2011 |
| 20110190234 | MYCOBACTERIUM MEMBRANE PROTEASE AS A TARGET FOR INHIBITORS OF INTRABACTERIAL pH HOMEOSTASIS The present invention is directed to methods and compounds for inhibiting bacterial growth and treating a bacterial infection in a subject. These methods involve providing an inhibitor of intrabacterial pH homeostasis, including inhibitors of the Mycobacterium tuberc... | 08/04/2011 |
| 20110189252 | PHARMACEUTICAL COMPOSITIONS COMPRISING LIGNANS AND THEIR DERIVATIVES FOR TREATING HYPERPLASTIC DISEASES The present invention relates to a pharmaceutical composition comprising specific compounds which may be obtained from Leontopodium alpinum Cass. (Edelweiss). A preferred compound is leoligin (=(2S,3R,4R)-4-(3,4-dimethoxybenzyl)-2-(3,4-dimethoxyphenyl)tetrahydrof... | 08/04/2011 |
| 20110165247 | DEVICE FOR THE TRANSDERMAL ADMINISTRATION OF A ROTIGOTINE BASE The invention relates to a polymer matrix suitable for the transdermal administration of rotigotine [(−)-5, 6, 7, 8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphtol], containing a matrix for the transdermal administration of rotigotine [(−)-5, 6, 7, 8-tetrah... | 07/07/2011 |
| 20110160276 | CURCUMIN DERIVATIVES A compound has Formula VIII where, X is —C(O)R, —C(O)OR, —CN, —NO2, —S(O)2R′, —P(O)(OR)2; each R is individually H, alkyl, or alkenyl; R′ is alkyl or akenyl; R1 is aryl, alkenyl, arylalkenyl, heterocyclyl, or h... | 06/30/2011 |
| 20110160273 | CO-CRYSTALS OF DULOXETINE AND COX-INHIBITORS FOR THE TREATMENT OF PAIN The present invention relates to co-crystals of duloxetine and co-crystal formers selected from COX-INHIBITORs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.... | 06/30/2011 |
| 20110152343 | PROTEASE INHIBITORS AND BROAD-SPECTRUM ANTIVIRAL Caspace inhibition provides inhibition of viral infection across a wide collection of caspaces and viruses. Caspace inhibition, the prevention of the formation of active caspaces, can be achieved either through gene therapy, protein binding an inhibition, or through sma... | 06/23/2011 |
| 20110152797 | PROSTAGLANDINS AND ANALOGUES AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE The present invention relates to cyclopentane heptenoic acid-5-cis-2-(3α-hydroxy or lower alkyloxy-5-thienylpentyl)-3,5-dihydroxy, [1α, 2β, 3α, 5α] compounds, lower alkyl, hydroxyl lower alkyl and indole lower alkyl amides and esters thereof as potent ocular hypote... | 06/23/2011 |
| 20110152291 | NOVEL AROMATIC COMPOUNDS AND THEIR USE IN MEDICAL APPLICATIONS Pharmaceutical compositions comprising at least one compound of the formulas (Ia) or (Ib) and a pharmaceutically acceptable carrier wherein the symbols have the following meaning —X- is e.g. and Y being e.g. or the pharmaceutically acceptable salts can be applied to m... | 06/23/2011 |
| 20110152315 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES There is provided novel compounds capable of modulating the G-protein-coupled receptor GPR40, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatment of conditions such as type I1 diabetes, hypertensi... | 06/23/2011 |
