Actor Marlon Brando has four patents, all named "Drumhead tensioning device and method."
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| Application No. | Application Title | Issue Date |
| 20120108530 | Enhanced Neoglycosides Through Neoglycosylation and Methods of Use Thereof Using neoglycosylation, the impact of differential glycosylation upon the divergent anticancer and anti-HIV properties of the triterpenoid betulinic acid (BA) was examined. Each member from a library of 37 differentially glycosylated BA variants was tested for anticance... | 05/03/2012 |
| 20120052124 | SILK FIBROIN SYSTEMS FOR ANTIBIOTIC DELIVERY The present invention provides for silk fibroin-based compositions comprising one or more antibiotic agents for prevention or treatment of microbial contamination, methods of making antibiotic-containing silk scaffold, methods of stabilizing antibiotics in silk scaffold... | 03/01/2012 |
| 20120010163 | NOVEL ANTIBACTERIAL COMPOUNDS, METHODS OF MAKING THEM, AND USES THEREOF The present invention relates to novel therapeutics with antibacterial activity, processes for their preparation, and pharmaceutical, veterinary and nutritional compositions containing them as active ingredients. The present invention also relates to uses of the novel t... | 01/12/2012 |
| 20110319350 | GLYCOSIDE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF The present invention provides glycoside compounds, methods of preparing such compounds, pharmaceutical compositions comprising such compounds, and a method for the treatment of hyperproliferative diseases using the same.... | 12/29/2011 |
| 20110301109 | Phenylpyrimidone Compounds, the Pharmaceutical Compositions, Preparation Methods and Uses Thereof The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds of the following formula I, the p... | 12/08/2011 |
| 20110195025 | ANIONIC OLIGOSACCHARIDE CONJUGATES The invention relates to anionic oligosaccharide conjugates that may be used to mimic the structure and/or activity of the anionic bioactive molecules known as glycosaminoglycans (GAGs).... | 08/11/2011 |
| 20110195921 | ELIMINATION OF A CONTAMINATING NON-HUMAN SIALIC ACID BY METABOLIC COMPETITION The disclosure provides a method of reducing or eliminating Neu5Gc in a cell culture or in a human subject. The method includes flooding the system with the human sialic acid i\7-acetylneuraminic acid (Neu5Ac) in glycosidically-bound or free form, or its precursor N-ace... | 08/11/2011 |
| 20110190233 | ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE The invention relates to anionic conjugates of glycosylated bacterial metabolites that may be used to mimic the structure and/or activity of the anionic bioactive molecules known as glycosaminoglycans (GAGs). The invention also relates to processes for the preparation o... | 08/04/2011 |
| 20110190385 | Methods and Products for Reawakening Retrocyclins Products and methods are provided for the restoring the endogenous expression of theta-defensins, such as retrocyclin-1, in mamallian cells. The present invention also includes products and methods for inhibiting sexually transmitted virus entry, e.g., HIV-1 virus entry... | 08/04/2011 |
| 20110189265 | THERAPEUTIC USE OF NEW PHARMACEUTICAL PREPARATIONS CONTAINING ANTITUMORAL DRUGS BOUND TO HYALURONIC ACID IN THE TREATMENT OF NEOPLASIAS The present invention describes the new use in the oncologic field of bioconjugates as differentiating agents obtained by the conjugation between hyaluronic acid (HA) and a chemotherapeutic product (identified hereafter with the trade-name ONCOFID®) among which, in par... | 08/04/2011 |
| 20110178037 | HYDROPHOBICALLY ENHANCED AMINOGLYCOSIDES Hydrophobically enhanced aminoglycosides have been prepared and shown to be effective antibacterial agents. These agents may be used in the treatment or prevention of various bacterial infections. Methods of preparing these agents also permit facile synthetic access. Fo... | 07/21/2011 |
| 20110178379 | TISSUE ASSESSMENT A method of aiding in the diagnosis or prediction of degenerative joint disease in a joint of a patient. The method comprises obtaining a test spectrum of Raman scattered radiation from cartilage tissue in the joint, and analysing the test spectrum, or one or more regio... | 07/21/2011 |
| 20110171187 | DIETARY SUPPLEMENTS FOR PROMOTION OF GROWTH, REPAIR, AND MAINTENANCE OF BONE AND JOINTS The present invention provides a dietary supplement that promote the growth, repair, and maintenance of mammalian bone and joint connective tissue. In particular, the dietary supplement comprises a combination of at least one metal chelate and at least one chondroprotec... | 07/14/2011 |
| 20110144030 | CONJUGATE OF HYALURONIC ACID FOR COSMETIC TREATMENT AND PREPARATION METHOD This invention discloses a new conjugate compound that comprises at least one HA oligomer derivatised through one thiolated linker, whereby it binds to at least one metal nanoparticle, such as, for example, a gold nanoparticle. Moreover, it discloses methods of obtainin... | 06/16/2011 |
| 20110124573 | Osmoprotective Complexes for Prevention of Intra-cellular Dehydration in Mammals This invention relates to certain Aloesin derivatives with natural amino acids, peptides, and amino sugars (formula I). The compounds of the present invention possess osmoprotective properties, which are suitable for topical or oral application to treat dermatological d... | 05/26/2011 |
| 20110053880 | COMPOSITION FOR TREATMENT OF TUBERCULOSIS The invention relates to a pharmaceutical composition comprising a compound preventing EthR from binding to the ethA promoter, for example a compound of formula 1 wherein R1 is optionally substituted phenyl or optionally substituted pyridyl; R2 (CH... | 03/03/2011 |
| 20110053881 | 6-Disubstituted Or Unsaturated Bicyclic Nucleic Acid Analogs The present disclosure describes 6-disubstituted bicyclic nucleosides, oligomeric compounds prepared therefrom and methods of using the oligomeric compounds. More particularly, the 6-disubstituted bicyclic nucleosides each comprise a 2′-O—C(Ri)(R2)-4′ or 2′-O—... | 03/03/2011 |
| 20110052702 | Method and Apparatus for Producing Organic Nanotubes An object of the present invention is to provide a method and apparatus capable of continuously producing organic nanotubes, wherein an organic nanotube material dispersion solution consisting of an organic nanotube material and an organic solvent is pressurized and cau... | 03/03/2011 |
| 20110044901 | NOVEL COMPOUNDS The present invention is directed to sulphated compounds comprising at least one glycosidic amine group, and polysaccharide, oligosaccharide, peptide and protein derivatives comprising such compounds, and mixtures thereof. The present invention is also directed to metho... | 02/24/2011 |
| 20100323033 | CANCER SENSITIZER COMPRISING CHLOROGENIC ACID The present invention relates to a cancer sensitizer comprising chlorogenic acid or a derivative thereof. In particular, the present invention relates to a cancer sensitizer comprising chlorogenic acid or a derivative thereof, which can make cancer cells sensitive to an... | 12/23/2010 |
| 20100317608 | Dithiol Compounds, Derivatives, and Uses Therefor Dithiol compounds and derivatives thereof are disclosed. The agents are useful for treating ocular disease, especially presbyopia and cataract.... | 12/16/2010 |
| 20100316704 | PLATINUM COMPLEXES AND METHODS OF USE The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the... | 12/16/2010 |
| 20100311673 | SULFANYL-TETRAHYDROPYRAN-BASED COMPOUNDS AND METHODS OF THEIR USE Sulfanyl-tetrahydropyran-based compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment of diseases and disorders such as diabetes and obesity are disclosed.... | 12/09/2010 |
| 20100297046 | Compositions and Methods Related to Fructosamine-3-Kinase Inhibitors The invention relates to compounds and methods for inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin, by way of fructosamine-3-kinase inhibition, thereby treating or prevention various diseases, disorders or conditions. Add... | 11/25/2010 |
| 20100286079 | COMPOSITION COMPRISING COVALENT CONJUGATES OF CHITOSAN AND AN ACIDIC DRUG AND PARENTERAL ADMINISTRATION The present invention relates to a composition comprising an aqueous solvent and a conjugate of at least one hydrophilic polymer having a primary amine functional group, a derivative or monomer thereof and at least one acidic drug; a method for its preparation and use t... | 11/11/2010 |
| 20100286080 | AQUEOUS COMPOSITION COMPRISING CHITOSAN AND AN ACIDIC DRUG The present invention relates to a composition comprising an aqueous solvent and a conjugate of at least one hydrophilic polymer having a primary amine functional group, a derivative or monomer thereof and at least one acidic drug; a method for its preparation and use t... | 11/11/2010 |
| 20100278804 | Methods And Formulations For Modulating Lyn Kinase Activity And Treating Related Disorders The present invention relates to compounds and pharmaceutically acceptable salts thereof and formulations comprising the compounds or a pharmaceutically acceptable salts thereof that are useful in modulating lyn kinase activity. In particular, the compounds or a pharmac... | 11/04/2010 |
| 20100267655 | Glycosylated Warfarin Analogs and Uses Thereof The present invention discloses a set of glycosylated warfarin analogs which are useful as anti-tumor or anti-metastatic agents and as reagents for studying sugar uptake in cells.... | 10/21/2010 |
| 20100260669 | Treatment of Seasonal Conditions Through Modulation of the Autonomic Nervous System Multi-dose active agent packages and methods for using the same for treating a subject for a condition are provided. Aspects of the invention include a multi-dose active agent package containing a plurality of unit dosage forms of an active agent configured to modulate ... | 10/14/2010 |
| 20100256078 | NEOGLYCORANDOMIZATION AND DIGITOXIN ANALOGS The present invention provides methods of producing libraries of compounds with enhanced desirable properties and diminished side effects as well as the compounds produced by the methods. In preferred embodiments, methods of the present invention use a universal chemica... | 10/07/2010 |
| 20100197590 | 4-AMINO-7,8-DIHYDROPYRIDO[4,3-d]PYRIMIDIN-5(6H)-ONE DERIVATIVES The invention provides compounds of Formula (Ia) or pharmaceutically acceptable salts thereof, as well as the preparation, compositions and uses thereof, where R1, R2, R3, and... | 08/05/2010 |
| 20100190686 | NOVEL SECRETED PROTEINS OF ADIPOCYTES FOR DIAGNOSTIC PURPOSES The present invention relates to the discovery of polypeptide biomarkers excreted into the blood stream (serum or plasma) and/or urine from adipocytes and their use to determine the existence of metabolic syndrome (prediabetic) and/or diabetic conditions (including type... | 07/29/2010 |
| 20100119587 | SOLID LIPIDIC PARTICLES AS PHARMACEUTICALLY ACCEPTABLE FILLERS OR CARRIERS FOR INHALATION The present invention relates to new compositions of (active) solid lipidic particles (SLP), e.g. for inhalation, and their use as carriers or as fillers in pharmaceutical compositions. It also relates new formulations obtained by mixing a SLP composition of the inventi... | 05/13/2010 |
| 20100105631 | Inositol Compounds and Uses of Same in the Treatment of Diseases Characterized by Abnormal Protein Folding or Aggregation or Amyloid Formation, Desposition, Accumulation or Persistence Inositol derivatives are described that are represented by the structural formula I wherein X is a radical of scyllo-inositol wherein one or more of R1, R2, R3, R4,... | 04/29/2010 |
| 20100062991 | NOVEL 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES WHICH ARE SUBSTITUTED WITH FLUORINE, METHOD FOR PRODUCING THE SAME, DRUGS CONTAINING SAID COMPOUNDS AND USE THEREOF This invention relates to Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with fluorine, method for producing the same, drugs containing said compounds and use thereof.... | 03/11/2010 |
| 20100035834 | NOVEL 1,4-BENZOTHIEPIN-1, 1-DIOXIDE DERIVATIVES WITH IMPROVED PROPERTIES METHOD FOR PRODUCING THE SAME, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF This invention relates to Novel 1,4-benzothiepin-1,1-dioxide derivatives with improved properties, method for producing the same, drugs containing said compounds and use thereof.... | 02/11/2010 |
| 20090304629 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS The present invention relates to compounds of Formula I, II or III, or a pharmaceutically acceptable salt, ester, or prodrug, thereof:
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| 20090281051 | CARBA-SUGAR AMINE DERIVATIVE AND GLYCOLIPID METABOLIC DISORDER TREATING AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT A carba-sugar amine derivative represented by the following formula (1) or (2) is used as the active ingredient of a β-galactosidase inhibitor or a glycolipid metabolic disorder treating agent. Wherein each ... | 11/12/2009 |
| 20090264342 | COMPOSITIONS AND METHODS FOR ANTIBIOTIC POTENTIATION AND DRUG DISCOVERY The present invention provides methods for identifying target genes whose partial or complete functional inactivation potentiates the activity of an antibiotic agent, e.g., a quinolone antibiotic. The invention further provides methods for identifying agents that modula... | 10/22/2009 |
| 20090233995 | Use of drug combinations for treating insulin resistance The present invention provides pharmaceutical compositions comprising: (a) a modulator of hepatic parasympathetic tone, (b) at least one diabetes drug, and (c) a pharmaceutically acceptable carrier. The present invention includes methods for the treatment and/or prevent... | 09/17/2009 |