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Patent No. 6637829

Decorative Jeweled Wheel Cover

An improved wheel is provided wherein decorative items such as gem stones are embedded in either the wheel surface, a special mounting section attached to the wheel surface, or to a spoke strap that wraps around each spoke and positions embedded gem stones on the outside surface of the spoke.

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Class 514/396 - Imidazoles


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the 1,3-diazole ring is imidazole
No. of applications: 372
Last issue date: 05/24/2012


                9    
Application No.Application TitleIssue Date
20060014805Pesticidal fluoroalkene derivatives
Pesticidal fluoroalkene derivatives (I) wherein A is oxygen, NRa; Ra is hydrogen; optionally halogenated alkyl, alkenyl, alkynyl; X is hydrogen, halogen; optionally halogenated alkyl or phenyl; R1,R2 are hydrogen, halogen, hyd...
01/19/2006
20050261328Pharmaceutical composition comprising beta-3-adrenoceptor-agonists and antimuscarinic agents
A pharmaceutical composition useful in the treatment of functional bladder disorders comprising an antimuscarinic agent and a beta-3-adrenoceptor agonist is described. ...
11/24/2005
20050256169Nitric oxide scavengers
Therapeutic compositions capable of removing excess nitric oxide are provided. The therapeutic compositions include nitronyl nitroxide monoradicals, B12 derivatives, flavonoid derivatives, the like and combinations thereof. The therapeutic compositions can be utilized i...
11/17/2005
20050256167Preparation and use of imidazole derivatives for treatment of obesity
This invention relates to substituted imidazole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using ...
11/17/2005
20050238729Inhibition of biogenic sulfide production via biocide and metabolic inhibitor combination
Biogenic sulfide production is synergistically inhibited by treating sulfate-reducing bacteria (SRB) with a biocide and a metabolic inhibitor. The biocide directly kills a first portion of the SRB. The metabolic inhibitor inhibits sulfate-reducing growth of a second por...
10/27/2005
20050239856Method for prophylaxis and treatment of diabetic complications with 4{alpha-hydroxy-2-methyl-5-(1-imidazolyl)benzyl}-3,5-dimethylbenzoic acid and derivatives
The present invention relates to an agent for the prophylaxis and treatment of diabetic complications comprising, as an active ingredient, 4-[α-hydroxy-2-methyl-5(1-imidazolyl)benzyl]-3,5-dimethylbenzoic acid, an optically active compound thereof or a pharmaceutically ...
10/27/2005
20050234106Cycloalkyl inhibitors of potassium channel function
Novel cycloalkyl compounds useful as inhibitors of potassium channel function (especially inhibitors of the Kv1 subfamily of voltage gated K+ channels, especially inhibitors Kv1.5 which has been linked to the ultra-rapidly activating del...
10/20/2005
20050227978Fibrosis inhibitor
Medicament being useful as a fibrosis inhibitor for organs or tissues, which comprises a compound of the formula (I):
wherein Ring Z is optionally substituted pyrrole ring, etc.; W2 is —CO—, —SO2—, optionally substituted C1
10/13/2005
20050222136Active substance combination
The present invention relates to an active substance combination including at least one substituted carbinol compound and at least one non-steroidal anti-inflammatory drug (NSAID), a medicament including the active substance combination, a pharmaceutical formulation inc...
10/06/2005
20050222135Active substance combination
The present invention relates to an active substance combination comprising at least one substituted carbinol compound and at least one opioid, a medicament comprising said active substance combination, a pharmaceutical formulation comprising said active substance combi...
10/06/2005
20050209275Beta 2-adrenergic receptor agonists
Disclosed are multibinding compounds which are β2-adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor. ...
09/22/2005
20050203064Novel oxidized thioether derivatives
The present invention provides the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their m...
09/15/2005
20050203111Compositions and methods for preventing and treating skin and hair conditions
The present invention discloses compositions and methods for the prevention and treatment of skin and hair diseases, such as, for example, alopecia, psoriasis, and keloids. In one embodiment, the present invention discloses a method for preventing and treating hair loss...
09/15/2005
20050197377CCK-1 receptor modulators
Certain imidazole compounds are CCK1 modulators useful in the treatment of CCK1 mediated diseases. ...
09/08/2005
20050186195Use of creatine or creatine compounds for skin preservation
The present invention relates to the use of creatine compounds such as, for example, creatine, creatine phosphate or analogs of creatine, such as creatine-pyruvate, creatine-ascorbate, cyclocreatine, 3 guanidinopropionic acid, guanidinoacetate, homocyclocreatine, guanid...
08/25/2005
20050187276Compounds, compositions and methods
The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF and HIF regulated genes, inhibiting angiogenesis, inducing cell cycle arrest in tumor cells, and treating cell proliferating diseases or conditions. ...
08/25/2005
20050186194Use of creatine or creatine compounds for skin preservation
The present invention relates to the use of creatine compounds such as, for example, creatine, creatine phosphate or analogs of creatine, such as creatine-pyruvate, creatine-ascorbate, cyclocreatine, 3 guanidinopropionic acid, guanidinoacetate, homocyclocreatine, guanid...
08/25/2005
20050171163MCP-1 receptor antagonists and methods of use thereof
The present invention relates to sulfones that are useful in the treatment of chemokine-mediated disorders. In certain embodiments, the present invention concerns the compounds that are MCP-1 receptor antagonists. ...
08/04/2005
20050171176Pharmaceutically active aromatic guanylhydrazones
The present invention relates to aromatic guanylhydrazone compounds and their use as pharmaceutically active agents, especially for prophylaxis and treatment of virally caused diseases and infections, including opportunistic infections. The inventive guanylhydrazone com...
08/04/2005
20050171069Methods and reagents for the treatment of multiple sclerosis
The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sust...
08/04/2005
20050159470Histone deacetylase inhibitors
Histone deacetylase inhibitors and uses thereof are provided that have the general
Z-Q-L-M
07/21/2005
20050148547Fungicidal mixtures based on benzamidoxime derivatives and azoles
Fungicidal mixtures, comprising as active components
(1) a benzamidoxime derivative of the formula I where the substituent and the index may have the following meanings:
    • 07/07/2005
20050142628Use
The present invention relates to the use of NAD(P)H oxidase inhibitors to increase cellular uptake of glucose and in the treatment and/or prevention of diseases caused by insulin resistance or diseases related thereto, such as type II diabetes. Specifically, the inventi...
06/30/2005
20050137173Bicyclic cannabinoid agonists for the cannabinoid receptor
Novel polycyclic cannabinoid analogs are presented which have preferentially high affinities for the cannabinoid CB2 receptor sites. The improved receptor affinity makes these analogs therapeutically useful as medications in individuals and animals for treatment of pain...
06/23/2005
20050131043Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles
This invention relates to a compound and the use of the compound of the formula
wherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies —CH═CH— or —C≡C—; and B signifies ...
06/16/2005
20050124632Remedies and/or preventives for diabetic ischemic heart diseases
An agent for therapeutic and/or prophylactic treatment of heart failure or arrhythmia in diabetic ischemic heart disease, which comprises as an active ingredient an aminobenzenesulfonic acid derivative represented by the following general formula (I):
(wherein...
06/09/2005
200501073833-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE
3-Arylphenyl sulfide derivatives represented by general formula (I):
(wherein R is a C2-C6 alkyl group, a C2-C6 alkenyl group, a C2-C6 alkynyl group or the like, B0 to B2 a...
05/19/2005
20050107449Peroxisome proliferator activated receptor modulators
The present invention is directed to compounds represented by the following structural formula, and pharmaceutically acceptable salts thereof, Formula I. (Formula I); wherein: (a) R5 is selected from the group consisting of (C1-C6) alkyl, (C1<...
05/19/2005
20050107442Compounds that modulate PPAR activity and methods of preparation
This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agent...
05/19/2005
20050101585Use of selective CB1-antagonists in medical treatments
The use of selective CB1 receptor antagonistic compounds for treating and/or inhibiting CB1 receptor related diseases in juvenile patients (pediatric treatment), e.g. in particular obesity in juvenile patients, and/or for the treatment and/or inhib...
05/12/2005
20050085523Imidazolyl and pyrazolyl ethyne compounds
In accordance with the present invention, there is provided a novel class of heterocyclic compounds. Compounds of the invention contain a substituted, unsaturated five, six or seven membered heterocyclic ring that includes at least one nitrogen atom and at least one car...
04/21/2005
20050085521Optically active azole derivative and process for producing the same
A method for producing an optically active 2-phenyl-2,3,-dihydroxypropyl azole derivative, which is a useful compound in various fields. An optically active α-hydroxycarboxylic acid derivative represented by general formula (1) is used as a starting material and is al...
04/21/2005
20050080122Anti-viral compounds
The present invention relates generally to compounds useful in the amelioration of symptoms associated with viral infection. More particularly, the present invention relates to the use of compounds which exhibit a physiological effect on membranous and/or transmembranou...
04/14/2005
20050075359Large conductance calcium-activated K channel opener
There is disclosed a large conductance calcium-activated K channel opener comprising a compound of the formula (I):
wherein R1 is aminosulfonyl, alkylsulfonyl, etc., R2 is hydrogen or halogen, R3 and R4 are hydrogen,...
04/07/2005
20050075378Modulators of peroxisome proliferator activated receptors (ppar)
The present invention is directed to a compound of formula I, and pharmaceutically acceptable salts, solvates, hydrates or stereoisomer thereof, which are useful in treating Syndrome X, Type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertensio...
04/07/2005
20050075376Cycloalkyl heterocycles for treating Hepatitis C virus
Compounds of Formula I are disclosed which inhibit hepatitis C NS5B RNA-dependent RNA polymerase and are useful for treating hepatitis C. Compositions and methods of using these compounds are also disclosed. ...
04/07/2005
20050075375Heterocyclic compounds for treating hepatitis C virus
The invention is directed to heterocyclic compounds and pharmaceutical compositions of the same for treating Hepatitis C virus. ...
04/07/2005
20050070538Compounds and uses thereof in modulating amyloid beta
Novel compounds, compositions, and kits are provided. Methods of modulating Aβ levels, and methods of treating a disease associated with aberrant Aβ levels are also provided. ...
03/31/2005
20050054706Pharmaceutically active compounds and methods of use
The invention provides substituted pyrazolidinone compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing ...
03/10/2005
20050054618Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases
The present invention provides methods of treatment and prevention of early cardiac and early cardiovascular diseases, for instance of ischemic origin, such as left ventricular hypertrophy, coronary artery disease, essential hypertension, acute hypertensive emergency, c...
03/10/2005
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