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| Application No. | Application Title | Issue Date |
| 20120021989 | GENETIC MARKERS FOR RISK MANAGEMENT OF ATRIAL FIBRILLATION AND STROKE The invention relates to procedures and methods of determining a susceptibility to cardiac arrhythmia, including Atrial Fibrillation, Atrial Flutter and Stroke, by assessing the presence or absence of alleles at polymorphic markers found to be associated with risk of th... | 01/26/2012 |
| 20110244028 | METHOD OF SOLUBILIZING BIOLOGICALLY ACTIVE COMPOUNDS The invention describes a method of preparing lipid compositions by associating pH sensitive compounds which maybe weak acids, bases or amphoteric compounds with at least one ionisable or pH sensitive group and low water solubility into preformed and standardised lipid ... | 10/06/2011 |
| 20110165259 | COMPOSITE ORGANIC COMPOUND POWDER FOR MEDICAL USE, METHOD FOR PRODUCING SAME AND SUSPENSION OF SAME [Problem to be Solved] The purpose of present invention is to provide a medicine which has low contamination with a fine-pulverizing medium, is safe and has improved bioavailability. [Solution] A method for producing a composite organic com... | 07/07/2011 |
| 20110152328 | Combination Therapy For Glaucoma Disclosed herein is method of treating glaucoma or ocular hypertension comprising administering a prostaglandin agonist and a second therapeutically active agent to a mammal in need thereof, wherein said second therapeutically active agent is selected from: β-Blockers,... | 06/23/2011 |
| 20110144160 | Antagonists of Prostaglandin D2 Receptors Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with... | 06/16/2011 |
| 20110135604 | ANTIVIRAL COMPOUNDS The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.... | 06/09/2011 |
| 20110111021 | PHARMACEUTICAL PREPARATION The present invention provides a pharmaceutical preparation including a compartment containing a renin inhibitor as a pharmacologically active ingredient, and a compartment containing an HMG-CoA reductase inhibitor as a pharmacologically active ingredient, wherein one c... | 05/12/2011 |
| 20110098221 | INHIBITORS OF Akt ACTIVITY Invented are novel hetero-pyrrole compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis.... | 04/28/2011 |
| 20110092486 | IH CHANNEL INHIBITORS FOR THE PROMOTION OF WAKEFULNESS The present invention relates to use of an Ih channel inhibitor for the manufacture of a medicament for the promotion of wakefulness in a subject in need thereof, in particular, wherein the subject is suffering from excessive sleepiness which may result from ... | 04/21/2011 |
| 20110086818 | METHODS, COMPOSITIONS, AND KITS FOR TREATING PAIN AND PRURITUS The invention features methods, compositions, and kits for selective inhibition of pain-and itch sensing neurons (nociceptors and pruriceptors) by drug molecules of small molecule weight, while minimizing effects on non-pain-sensing neurons or other types of cells.... | 04/14/2011 |
| 20110086761 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS The present invention relates to fungicidal compositions and their use for controlling oomycete pathogen induced disease or diseases in one or more plants.... | 04/14/2011 |
| 20100331186 | EMULSIFIABLE CONCENTRATE COMPOSITION Disclosed is an emulsifiable concentrate composition characterized by containing not less than 0.5% by weight but not more than 25% by weight of a hydrophobic agrochemically active compound, not less than 5% by weight but not more than 15% by weight of a surfactant, not... | 12/30/2010 |
| 20100323978 | Non-aqueous oil delivery system for ophthalmic drugs The present invention relates to a delivery system for ophthalmic drugs, and more particularly, to a non aqueous oil delivery system. Low concentrations of ophthalmic drugs suspended in an oil vehicle delivery system are as therapeutically effective in man and animals a... | 12/23/2010 |
| 20100311770 | COMPOUND COMBINATIONS FOR INHIBITING CELL DIVISION AND METHODS FOR THEIR IDENTIFICATION AND USE The present invention provides in vitro assays, e.g., FtsZ GTPase assays, and/or in vivo assays and methods of use thereof to identify particular compounds and combinations of compounds that affect microbial cell division. The invention further provides such compounds a... | 12/09/2010 |
| 20100297113 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF This application describes quinone derivatives which target the redox site of Ape1/Ref1. Also included in the invention are pharmaceutical formulations containing the derivatives and therapeutic uses of the derivatives.... | 11/25/2010 |
| 20100292263 | CGRP RECEPTOR ANTAGONISTS WITH TERTIARY AMIDE, SULFONAMIDE, CARBAMITE AND UREA GROUPS Compounds of formula I: (wherein variables A, m, n, J, Re, Rf, R4, Ea, Eb, Ec, RPG and Y are as described herein) which are antagon... | 11/18/2010 |
| 20100286212 | Treating and Preventing Viral Infections Compounds that are useful in treating or preventing viral infections, such as influenza, are described herein. Further described are compositions made from these compounds and methods for using the compounds and their compositions in treating or preventing viral infecti... | 11/11/2010 |
| 20100247606 | INTRAOCULAR SUSTAINED RELEASE DRUG DELIVERY SYSTEMS AND METHODS FOR TREATING OCULAR CONDITIONS Biocompatible, bioerodible sustained release implants and microspheres for intracameral or anterior vitreal placement include an anti-hypertensive agent and a biodegradable polymer effective to treat an ocular hypertensive condition (such as glaucoma) by relapsing thera... | 09/30/2010 |
| 20100222333 | EXCIPIENT PRESERVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISED THEREOF Topically applicable pharmaceutical compositions contain at least one pharmaceutically active agent and an effective antimicrobial amount of a preservative excipient mixture and devoid of such amount of known preservative(s) as would otherwise itself impart an effective... | 09/02/2010 |
| 20100130432 | Non-Natural Amino Acids and Neurotensin Analogues Thereof This invention relates to non-natural desamino amino acid compounds, methods of making, and peptides containing these compounds as their N-terminus moieties. A preferred example is neurotensin (8-13) in which the N terminus is an alpha desamino N,N dimethyl homolysine r... | 05/27/2010 |
| 20100113544 | Suppressant for cerebral infarction attributed to long-time ischemia An object of the present invention is to provide a cerebral infarction suppressant which is effective for brain tissue necrosis after long-time ischemia as in actual cerebral infarction and has fewer side effects. The cerebral infarction suppressant of the present inven... | 05/06/2010 |
| 20100081678 | INDOLE COMPOUNDS AND THEIR USE AS RADIATION SENSITIZING AGENTS AND CHEMOTHERAPEUTIC AGENTS Indole derivatives that are useful in the treatment of cancer as a chemotherapeutic agent or radiosensitizing agent.... | 04/01/2010 |
| 20100029700 | 1-(2-ARYL-2-OXOETHYL)-3-PHENYL-1, 4-DIAZASPIRO [4.5]DEC-3-EN-2-ONE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORTER INHIBITORS Novel acetophenone compounds of formula (I), compositions containing (I), processes for the preparation of (I), and use of (I) as inhibitors of the glycine transporter, are provided. Definitions of Ar, R... | 02/04/2010 |
| 20090325993 | GLYT1 Transporter Inhibitors and Uses Thereof in Treatment of Neurological and Neuropsychiatric Disorders Compounds of formula (I) or a salt thereof are provided: wherein R1, R2, R3, R4, R5, R6, R7, R9, R10, X, n, p... | 12/31/2009 |
| 20090306161 | METHODS OF TREATING ALPHA ADRENERGIC MEDIATED CONDITIONS Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an α-adrenergic modulator. The compounds and methods are also useful for allevi... | 12/10/2009 |
| 20090297619 | NANOPARTICULATE ANTICONVULSANT AND IMMUNOSUPPRESSIVE COMPOSITIONS Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the agent following administration. The novel compositions release the agent foll... | 12/03/2009 |
| 20090286839 | PHYTONUTRIENT COMPOSITIONS FROM MUSHROOMS OR FILAMENTOUS FUNGI AND METHODS OF USE This invention is directed to treating disease states or conditions associated with the treatment and prevention of neurodegeneration and neurodegenerative disease states, and treatment of radiation damage. The invention relates to novel phytonutrient compositions and c... | 11/19/2009 |
| 20090270472 | METHOD TO USE OXYMETAZOLINE TO INTERRUPT THE DEVELOPMENT OF THE COMMON COLD SYNDROME This invention describes a new manner of treating the common cold. It claims that treatment with Oxymetazoline nasal spray at the time of onset of first cold symptom(s) can interrupt the development of the common cold syndrome and result in cure of the cold.... | 10/29/2009 |
| 20090270490 | METHODS INVOLVING ALDOSE REDUCTASE INHIBITION Embodiments of the invention include methods and compositions involving aldose reductase inhibitors for the treatment of inflammation, including inflammatory bowel disease, macular degeneration, or posterior capsule opacification.... | 10/29/2009 |
| 20090239918 | SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF The invention provides methods for treating pain in mammals. In particular, the invention provides well-defined aminoimidazolines, aminothiazolines, and aminooxazolines and pharmaceutical compositions thereof to treat pain.... | 09/24/2009 |
| 20090186834 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS Various azetidinone, pyrrolidine, imidazolidine, and oxazolidine derivatives are described, as are pharmaceutical compositions containing these compounds and methods of treatment of diseases using these compounds. Other embodiments are also described.... | 07/23/2009 |
| 20090182014 | INSECTICIDAL COMPOSITIONS COMPRISING COMPOUNDS HAVING INHIBITORY ACTIVITY VERSUS ACYL COA: CHOLESTEROL ACYLTRANSFERASE OR SALTS THEREOF AS EFFECTIVE INGREDIENTS The present invention relates to insecticidal compositions comprising compounds having an inhibitory activity versus acyl CoA: cholesterol acyltransferase (ACAT) or salts thereof as effective ingredients. The compounds having inhibitory activity versus ACAT have an exce... | 07/16/2009 |
| 20090170875 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS This invention relates to compounds of the Formula (I):
| 07/02/2009 |
| 20090118257 | 4-(p-QUINONYL)-2-HYDROXYBUTANAMIDE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES Methods of treating or suppressing mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, and stroke (MELAS), Kearns-Sayre Syndrome (KSS), are disclosed, as well as co... | 05/07/2009 |
| 20090117208 | AMINO ACID COMPOSITION AND SUPPLEMENTARY LIQUID CONTAINING THE SAME An amino acid composition comprises alanine, arginine, aspartic acid, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, valine, and glutamine. The amino acid composition of the pr... | 05/07/2009 |
| 20090118237 | Carisoprodol, Phenytoin and Fosphenytoin Articles and Methods A method of using carisoprodol, phenytoin or fosphenytoin comprises informing a user that co-administration of carisoprodol with phenytoin or fosphenytoin results in an increase in free phenytoin blood levels, a decrease in total phenytoin levels, or both. In another em... | 05/07/2009 |
| 20090111832 | Imidazolidinone Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease The present invention is directed to imidazolidinone compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed ... | 04/30/2009 |
| 20090082313 | Multikinase Inhibitors for Use in the Treatment of Cancer The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I):
| |
| 20090062359 | Injectable capsaicin with non-local anesthetic sodium channel-blocker adjunctive agent Disclosed in certain embodiments is a method for relieving pain at a site in a human or animal in need thereof, comprising administering by injection or infiltration, a dose of a capsaicinoid and coadministering a non-anesthetic sodium channel blocker.... | 03/05/2009 |
| 20090022780 | HYDROGEL The invention is related to gel preparations capable of absorbing as well as releasing liquid, and the use of such gel preparations in the treatment of wounds.... | 01/22/2009 |
