...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Application No. | Application Title | Issue Date |
| 20120128800 | DIETARY SUPPLEMENTS CONTAINING EXTRACTS OF ARONIA AND METHOD OF USING SAME TO PROMOTE WEIGHT LOSS A dietary supplement composition comprising aronia extract containing at least 20% anthocyanins by dry weight. The aronia extract is derived from the aronia melanocarpa plant. The aronia extract comprises approximately 10%-30% of the dry weight of the composition. A vit... | 05/24/2012 |
| 20120128777 | COMPOSITIONS CONTAINING LIPID MICRO- OR NANOPARTICLES FOR THE ENHANCEMENT OF THE DERMAL ACTION OF SOLID PARTICLES The invention is related to compositions which can be used as dermal formulations for supporting the skin to restore normal conditions in case of e.g. irritated skin, or to support medical therapy of skin with atopic dermatitis symptoms, atopic dermatitis, psoriasis or ... | 05/24/2012 |
| 20120128662 | SUBSTITUTED IMIDAZOQUINOXALINES The present invention relates to substituted imidazoquinoxaline compounds of general formula (I) as inhibitors of Mps-1 Kinase or TTK, and being active against inflammation and cancer. ... | 05/24/2012 |
| 20120128731 | BIOCOMPATIBLE CARRIER AND METHOD FOR FABRICATING THE SAME The invention provides a biocompatible carrier and method for fabricating the same. The biocompatible carrier includes: a gel, and a plurality of metal nanoparticles, an organic compound or combinations thereof embedded in the gel, wherein the metal nanoparticles, the o... | 05/24/2012 |
| 20120128805 | LONG-LASTING GUSTATORY AND/OR OLFACTORY AVERSION VETERINARY COMPOSITIONS FOR BEHAVIOR MODIFICATION Disclosed herein are gustatory and/or olfactory aversion compositions comprising one or more bitterants and appropriate adhesives or tackifiers, and the like, which provide a long-lasting effect. The compositions are useful for behavior modification, especially in anima... | 05/24/2012 |
| 20120107323 | KINASE PROTEIN BINDING INHIBITORS The invention provides compounds capable of treating a subject suffering from or being susceptible to a cell proliferative disorder (especially, cancer), methods of identifying and using the compounds, pharmaceutical compositions and kits thereof.... | 05/03/2012 |
| 20120107307 | DIHYDROPYRIDIN SULFONAMIDES AND DIHYDROPYRIDIN SULFAMIDES AS MEK INHIBITORS This invention concerns N-(ortho phenylamino dihydropyridyl)sulfonamides and N-(ortho phenylamino dihydropyridyl), N′-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment of cancer and other hyperproliferative diseases.... | 05/03/2012 |
| 20120082717 | COMPLEX, MULTILAYER USING THE SAME, AND DEVICE COATED WITH THE MULTILAYER Disclosed herein is a complex, wherein micelles and/or liposomes dispersed in hyaluronic acids and/or hyaluronic acid derivatives, with a drug and/or functional material loaded in the micelles and/or the liposomes. The complex can release the drug and/or functional mate... | 04/05/2012 |
| 20120082703 | PHARMACEUTICAL COMPOSITION AND USE OF THE PHARMACEUTICAL COMPOSITION FOR THE TREATMENT, PROPHYLAXIS OR PREVENTION OF NEOPLASTIC DISEASES IN HUMANS AND ANIMALS The present invention relates to pharmaceutical compositions comprising polyfunctional metal phenolates that have biological applications as an anticancer adjuvant, cytoprotective antimetastatic agents and antimutagenic agents when associated with chemotherapy drugs. | 04/05/2012 |
| 20120083461 | AGENT FOR INHIBITING PERITONEAL MEMBRANE THICKENING PROBLEM The present invention is directed to provide a thickening inhibitory agent for inhibiting peritoneal membrane thickening which enables inhibition/prevention or treatment of the peritoneal membrane thickening and which mitigates adve... | 04/05/2012 |
| 20120083460 | READILY WATER-SOLUBLE ISOQUERCITRIN COMPOSITION Disclosed is a method for improving the solubility of isoquercitrin in water. Also disclosed is a readily water-soluble isoquercitrin composition which has improved solubility in water due to the method. Specifically disclosed is a method for preparing an isoquercitrin ... | 04/05/2012 |
| 20120071428 | NANOCRYSTALLINE PHOTOCATALYTIC COLLOID, A METHOD OF PRODUCING IT AND ITS USE The present invention relates to a nanocrystalline photocatalyst active upon visible light irradiation, with a high degree of dispersion, stable in the form of a transparent colloidal solution in an aqueous environment, containing nanocrystals of titanium dioxide (TiO 03/22/2012 | |
| 20120070475 | Zero Calorie Polyphenol Aqueous Dispersions A method for stably dispersing microparticulated water insoluble bioactive polyphenol in a beverage by combining the bioactive polyphenol dissolved in an alkaline solution with an aqueous solution of at least one dispersion stabilizer. A composition comprising dispersed... | 03/22/2012 |
| 20120070487 | ALKYLSACCHARIDE COMPOSITIONS WITH NUTRACEUTICALS The present invention provides nutraceutical compositions with enhanced oral bioavailability. The compositions of the present invention include one or more alkylsaccharides admixed with one or more nutraceutical.... | 03/22/2012 |
| 20120053138 | FORMULATION OF A MIXTURE OF FREE-B-RING FLAVONOIDS AND FLAVANS FOR USE IN THE PREVENTION AND TREATMENT OF COGNITIVE DECLINE AND AGE-RELATED MEMORY IMPAIRMENTS The present invention provides a novel method for preventing and treating memory and cognitive impairment resulting from oxidative stress, inflammation and the process of aging, as well as, neurodegenerative conditions. The method is comprised of administering a composi... | 03/01/2012 |
| 20120053137 | Method for Treating Addiction Using Quercetin-Containing Compositions This invention relates to a method of treating addiction using a composition containing quercetin. Preferably, it also contains vitamin B3, and vitamin C.... | 03/01/2012 |
| 20120053136 | DIAGNOSIS AND TREATMENT OF DRUG-RESISTANT EWING`S SARCOMA Disclosed herein are diagnostic and prognostic methods for determining drug sensitivity and resistance in Ewing's sarcoma patients. Treatments for drug-resistant Ewing's sarcoma are also disclosed. The assays involve the detection of GSTM4 gene expression alone or in co... | 03/01/2012 |
| 20120045501 | CONNEXIN ENHANCES CHEMOTHERAPY-INCLUDED APOPTOSIS IN HUMAN CANCER CELLS INHIBITING TUMOR CELL PROLIFERATION The present invention provides methods and compositions for the inhibition of proliferation rate of target cells, for example tumor cells. In particular, a nucleic acid encoding a connexin protein, fragment, derivative or analog thereof can be incorporated into a target... | 02/23/2012 |
| 20120045523 | COMBINATION OF A TLR3 LIGAND AND A CHEMOTHERAPY AGENT WHICH ACTS ON THE INTRINSIC "APOPTOSIS" PATHWAY IN THE TREATMENT OF CANCER The present invention relates to a drug comprising separately or together (i) a TLR3 ligand and (ii) a chemotherapeutic agent that acts on the intrinsic apoptotic pathway, for simultaneous or sequential administration in the treatment of cancer, wherein the chemotherape... | 02/23/2012 |
| 20120040921 | COMPOSITIONS AND PRODUCTS CONTAINING S-EQUOL, AND METHODS FOR THEIR MAKING A composition for use in making commercial food and skin products comprising 5-equol or mixtures, including both a non-racemic mixture and a racemic mixture, of S-equol and R-equol. The composition can be used to make articles of commerce such as food supplements, pharm... | 02/16/2012 |
| 20120028908 | Methods of Manufacturing Crystalline Forms of Rapamycin Analogs A process for preparing a crystalline rapamycin analog includes: combining the rapamycin analog with an organic medium to form a mixture; incubating the mixture until the rapamycin analog crystallizes; and recovering the crystalline rapamycin analog. The organic medium ... | 02/02/2012 |
| 20120021036 | COMPOSITE NANOSTRUCTURES AND METHODS FOR MAKING AND USING THEM The invention provides nanostructures or products of manufacture for use as ex vivo or in vivo composition (e.g., a drug, or a therapeutic, diagnostic or imaging reagent) delivery vehicles. In one aspect, the invention provides nanoparticles comprising several compartme... | 01/26/2012 |
| 20120021046 | GLUCOSAMINE AND GLUCOSAMINE/ANTI-INFLAMMATORY MUTUAL PRODRUGS, COMPOSITIONS, AND METHODS Mutual prodrugs of glucosamine, and derivatives and analogs of glucosamine and an anti-inflammatory agent, compositions thereof, and methods for, e.g., treating disorders and conditions by administration of the compositions are provided. Topical compositions of glucosam... | 01/26/2012 |
| 20120022010 | USE OF FLAVONOIDS TO INCREASE THE BIOAVAILABILITY OF HESPERETIN The present invention relates generally to the field of hesperetin bioavailability. One embodiment of the present invention is directed at a composition that allows to increase the bioavailability of hesperetin and consequently to maximize the beneficial health effects ... | 01/26/2012 |
| 20120020877 | PROCESS AND INTRA-CERVICAL DEVICE FOR THE LOCAL RELEASE OF DRUGS IN THE LOCAL-REGIONAL TREATMENT OF CERVICAL CANCER An intrauterine device and more specifically an intracervical device (ICD) for the local release of drugs in the loco-regional treatment of tumours of the uterine cervix comprises an elongated stem (2) to be positioned in the cervical canal (15), this stem... | 01/26/2012 |
| 20120003288 | DISPERSION COMPOSITION AND METHOD FOR MANUFACTURING DISPERSION COMPOSITION The present invention provides: a dispersion composition including a poorly water-soluble polyphenol compound, an emulsifier including a sucrose fatty acid ester, and a water-soluble polymer, in which a content of a polyglycerin fatty acid ester in the composition is 0,... | 01/05/2012 |
| 20120004189 | COMPOSITIONS AND PRODUCTS CONTAINING S-EQUOL, AND METHODS FOR THEIR MAKING A composition for use in making commercial food and skin products comprising S-equol or mixtures, including both a non-racemic mixture and a racemic mixture, of S-equol and R-equol. The composition can be used to make articles of commerce such as food supplements, pharm... | 01/05/2012 |
| 20120003337 | HEALTH SUPPLEMENTS CONTAINING PHYTO-OESTROGENS, ANALOGUES OR METABOLITES THEREOF Compositions enriched with natural phyto-oestrogens or analogues thereof selected from Genistein, Daidzein, Formononetin and Biochanin A. These may be used as food additives, tablets or capsules for promoting health in cases of cancer, pre-menstrual syndrome, menopause ... | 01/05/2012 |
| 20110311651 | CARDENOLIDES FOR THE TREATMENT OF OCULAR CANCER The instant invention provides methods of using a class of compounds known as cardenolides in the treatment of proliferative diseases such as cancer. In particular, the instant invention provides methods of treating ocular cancer {e.g., retinoblastoma) using intraarteri... | 12/22/2011 |
| 20110312904 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES The present invention provides compounds of Formula (I), compositions comprising an effective amount of a compound of Formula (I), optionally with chemotherapeutic drugs such as a tubulin-binding drug, and methods of their use for reducing the toxicity of cytotoxic agen... | 12/22/2011 |
| 20110312906 | TREATMENT OR REDUCTION OF MENOPAUSAL SYMPTOMS There is described a method for the treatment or prevention of menopausal symptoms or osteoporosis wherein there is administered to a subject in need of such treatment a therapeutically effective amount of the isotlavone formononetin, or a method for the treatment or pr... | 12/22/2011 |
| 20110312905 | STIMULUS-TRIGGERED PRODRUGS Set forth herein, inter alia, are compositions and methods for treating diseases with prodrugs. Provided herein are prodrug compositions for inhibiting the function of proteins, compositions and methods for treating diseases associated with oxidative compounds, oxidativ... | 12/22/2011 |
| 20110305754 | CONTROLLED RELEASE MICRO-CAPSULE FOR OSTEOGENIC ACTION The present invention relates to a microcapsule for controlled release of flavanoid compound and a process for preparation thereof. The microcapsule comprising a core particle consisting of a calcium salt, Pluronic F68 [poly (ethylene oxide-co-polypropylene co-polypropy... | 12/15/2011 |
| 20110301106 | Use of Icariside II in Manufacture of Products for Preventing or Treating Male or Female Sexual Dysfunction The present invention provides the use of icariside II or extract comprising thereof in manufacture of products for preventing or treating male or female sexual dysfunction, in particular, the use for improving pathological or organical changes in erectile tissues of pa... | 12/08/2011 |
| 20110300245 | Topical, palatable, anti-inflammatory and analgesic for specific application to intraoral, gingival and extraoral areas correlated with, and related to, the trigeminal nerve and its nerve branches and plexus. To mitigate, attenuate or prevent migraine-type headache, cluster-type headache, tension-type headache, post-traumatic headache, atypical facial pain and cervical muscle spasm as well as other idiopathic head or facial pain or discomfort, associated with, or exacerbated by, inflammation The invention is a new unique, palatable, topical, anti-inflammatory and analgesic designed around a specific set of painful conditions, with specifically designated applications, using a different methodology and formulation, with no NSAIDS, steroids or salicylites, th... | 12/08/2011 |
| 20110301107 | DERIVATIVES OF MORPHINE-6-GLUCURONIDE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS The disclosure relates to derivatives of morphine-6-glucuronide of formula (I) wherein R1 is as defined in the disclosure, or an acid addition salt thereof, as well as in hydrate or solvate form. The disclosu... | 12/08/2011 |
| 20110293696 | COMPOSITIONS AND METHODS FOR TREATING BRUISES A composition for the treatment of bruising is disclosed. The composition can include an antioxidant, one or more citrus flavanoids, as active agents along with a pharmaceutically acceptable excipient or filler. The compositions are nutriceutical formulations having the... | 12/01/2011 |
| 20110294750 | SURFACE STERILISATION BY MISTING WITH A BIOFLAVANOID SOLUTION There is described a method of sterilizing surfaces using flavonoids, for example mixtures containing inter alia naringin and neohesperidin, by misting.... | 12/01/2011 |
| 20110293537 | FORMULATIONS WITH ANTI-NEOPLASTIC ACTIVITY Pharmaceutical formulation comprising at least one aryl hydrocarbon receptor ligand and at least one cyclodextrin for the prevention and/or treatment of carcinomas, preferably squamous cell carcinomas, more preferably oral squamous cell carcinomas.... | 12/01/2011 |
| 20110286927 | ATF4 Inhibitors and Their Use for Neural Protection, Repair, Regeneration, and Plasticity In one aspect, the invention relates to a method for identifying a drug candidate with activity as a neuroprotective agent. The method includes determining whether a compound reduces ATF4 activity; and identifying the compound that reduces ATF4 activity as a drug candid... | 11/24/2011 |