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| Application No. | Application Title | Issue Date |
| 20120045448 | TRP-P8 ACTIVE COMPOUNDS AND THERAPEUTIC TREATMENT METHODS Compounds of the disclosure provide compositions, which are effective for prophylaxis and treatment of diseases or disorders, such as cell-proliferation, angiogenesis, or apoptosis mediated diseases. The disclosure encompasses compounds, analogs, prodrugs, metabolites, ... | 02/23/2012 |
| 20120035050 | Synergistic Combinations Of Active Ingredients The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in which | 02/09/2012 |
| 20120027741 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE The present invention relates to a pesticide composition intended for protecting plants, crops or seeds against fungal diseases or insect damages, and the corresponding methods of protection by application of the said composition. More precisely, the subject of the pres... | 02/02/2012 |
| 20120015947 | Cyclic hydroxylamine as psychoactive compounds A compound of formula (I): in which—
| 01/19/2012 |
| 20120004227 | CYCLOHEXANE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISM The present invention discloses novel cyclohexane derivatives having NPY Y5 receptor antagonistic activity. Specifically, the present invention discloses a compound represented by the formula (I), or a pharmaceutically acceptable salt or a solvate thereof: 01/05/2012 | |
| 20110311649 | NOVEL IMIDAZOLE DERIVATIVES The present invention relates to novel imidazole derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is halogen, C1-C4alkyl or C1-C4haloa... | 12/22/2011 |
| 20110190285 | METHODS OF TREATING A BOTULINUM TOXIN RELATED CONDITION IN A SUBJECT The present invention provides methods of treating a botulinum toxin related condition in a subject. In certain embodiments, the methods involve administering a compound of the following formulas: (I), (II), (III), (IV), (V). ... | 08/04/2011 |
| 20110171143 | Method of maintaining oral health in animals Use of a compound having the formula (I) in the manufacture of a medicament for the prevention or treatment of a disease caused by oral bacteria in an animal wherein R1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the ... | 07/14/2011 |
| 20110160200 | Nitroxyl Progenitors for the Treatment of Pulmonary Hypertension The invention relates to methods of treating, preventing or delaying the onset or development of pulmonary hypertension using hydroxyl donors or pharmaceutically acceptable salts thereof. The invention further relates to methods of reducing mean pulmonary arterial press... | 06/30/2011 |
| 20110159107 | Pesticidal Mixtures Comprising Isoxazoline Compounds II The present invention relates to pesticidal mixtures comprising as active components
| 06/30/2011 |
| 20110118254 | THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASE The main object of the present invention is to provide an agent for the treatment of inflammatory bowel diseases. The present invention relates to an agent for the treatment of inflammatory bowel diseases containing the heterocyclic derivat... | 05/19/2011 |
| 20110081426 | AMINOTHIAZOLE MODULATORS OF BETA-3-ADRENORECEPTOR The present invention relates to new aminothiazole modulators of beta-3-adrenoreceptor activity, pharmaceutical compositions thereof, and methods of use thereof. ... | 04/07/2011 |
| 20110046128 | NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS A series of novel compounds showing anticonvulsant, chemical countermeasure(s), and analgesic activities is described. Such pharmaceutically active compounds may also show utility in the treatment of other central nervous system (“CNS”) diseases and disorders, such ... | 02/24/2011 |
| 20100317618 | 1-BENZYL-3-HYDROXYMETHYLINDAZOLE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF DISEASES BASED ON THE EXPRESSION OF MCP-1 AND CX3CR1 The present invention relates to novel 1-benzyl-3-hydroxymethylindazole derivatives according to formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present inven... | 12/16/2010 |
| 20100311734 | Spiro Compounds Useful as Antagonists of the H1 Receptor The invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, for treating diseases and conditions of the central nervous system (CNS), in particular sleep disorders. ... | 12/09/2010 |
| 20100311710 | CYCLOBUTANEMETHANAMINE INHIBITORS OF MONOAMINE REUPTAKE The present invention relates to new cyclobutanemethanamine inhibitors of monoamine reuptake, pharmaceutical compositions thereof, and methods of use thereof. ... | 12/09/2010 |
| 20100292306 | Compositions And Methods For The Treatment Of Muscular Dystrophy Compositions and methods for treatment of individuals diagnosed with a dystrophin deficiency are disclosed. In particular, inhibitors of NFκB transactivation and/or inhibitors that suppress p65 expression are used to prevent and/or reverse muscle damage in animals or h... | 11/18/2010 |
| 20100286138 | Stable forms of N-(2,6-Dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide Polymorphic forms of N-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide are provided together with a process for the manufacture of said compound.... | 11/11/2010 |
| 20100280024 | RENIN INHIBITORS The present invention relates to renin inhibitors of formula (I), their pharmaceutically acceptable salts and pharmaceutical compositions containing them. The present invention also relates to a process of preparing compounds of general formula (I), their tautomeric for... | 11/04/2010 |
| 20100273650 | Fungicidal Mixtures Comprising a Substituted 3-Hydroxymethylpyridine and a Further Fungicidal Compound The present invention relates to mixtures of fungicidally active compounds comprising at least one substituted 3-hydroxymethylpyridin compound formula I and at least one further fungicidally active compound II.
| |
| 20100267669 | HETEROCYCLIC CETP INHIBITORS Compounds of formula Ia and Ib wherein A, B, C and R1 are described herein.... | 10/21/2010 |
| 20100261675 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE Conventional many fungicidal compositions have had practical problems such that either a preventive effect or a curing effect is inadequate, the residual effect tends to be inadequate, or the controlling effect against plant diseases tends to be inadequate depending upo... | 10/14/2010 |
| 20100260813 | Rodenticide Mixture A rodenticidal mixture comprising
| 10/14/2010 |
| 20100256150 | Cyclic hydroxylamine as psychoactive compounds A compound of formula (I): in which X represents O or CH2; R3 and R4 each independently represent hydrogen or C1-6 alkyl; p represent 0 or 1; and R represents a five- or six-membered saturated or unsaturated ring selected from... | 10/07/2010 |
| 20100240619 | FUNGICIDAL MIXTURES Disclosed is a fungicidal composition comprising (a) at least one compound selected from the compounds of Formula 1 N-oxides, and salts thereof,
| |
| 20100222303 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins as well as their prodrugs are disclosed. Such reverse-turn mimetic structures and prodrugs have utility over a wide range of fi... | 09/02/2010 |
| 20100222337 | FUNGICIDAL COMPOSITION CONTAINING CARBOXYLIC ACID AMIDE DERIVATIVE Conventional fungicidal compositions have had practical problems such that either a preventive effect or a curative effect is inadequate, the residual effect tends to be inadequate, or the controlling effect against plant diseases tends to be inadequate depending upon t... | 09/02/2010 |
| 20100215775 | USE OF C10-C14-ALKANEDIOLS IN THE PREPARATION OF A COMPOSITION FOR THE PROPHYLAXIS AND/OR TREATMENT OF MALASSEZIA-INDUCED DANDRUFF FORMATION The invention relates to the use of C10-C14-alkane-1,2-diols, in particular 1,2-decanediol, 1,2-dodecanediol and/or 1,2-tetradecanediol, in the preparation of a composition for the prophylaxis and/or treatment of Malassezia-induced dandruff formation, as well as ... | 08/26/2010 |
| 20100203103 | THERAPEUTIC COMPOSITIONS FOR TREATMENT OF INFLAMMATION OF OCULAR AND ADNEXAL TISSUES The present invention comprises a composition with means to inhibit the function of the inflammatory cytokine IL-1 and methods for using this composition to treat inflammatory disease of ocular and adnexal tissues by topical administration. The present invention also di... | 08/12/2010 |
| 20100184757 | FUNGICIDALLY ACTIVE COMPOUND COMBINATIONS Active compound mixtures comprising ipconazole and at least one further fungicidally active compound are highly suitable for protecting industrial materials against colonization and destruction by microorganisms.... | 07/22/2010 |
| 20100179115 | USE OF A GLUCOCORTICOID RECEPTOR II ANTAGONIST TO TREAT DEPRESSION IN PATIENTS TAKING IL-2 The invention pertains to the discovery that type II glucocorticoid receptor antagonists can be used in methods for reversing or inhibiting the symptoms of depression in patients receiving interleukin-2 treatment.... | 07/15/2010 |
| 20100173904 | Topical composition, topical composition precursor, and methods for manufacturing and using A tropical composition is provided. The topical composition can be prepared by diluting a topical composition precursor with water and adding additional components, if desired. The topical composition precursor can be prepared by melt processing a hydrophobic polymer co... | 07/08/2010 |
| 20100160327 | Modified Malonate Derivatives The present invention relates to a novel class of modified malonate derivatives. The modified malonate compounds can be used to treat cancer. The modified malonate compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal d... | 06/24/2010 |
| 20100152179 | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS A method for treating a patient suffering from disorders and deficits of the central nervous system associated with diabetes, associated with aging and neurodegeneration, comprising attention deficit disorder in general, attention deficit hyperactivity disorder (ADHD), ... | 06/17/2010 |
| 20100144674 | PYRIDAZINE DERIVATIVES The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is hydrogen, C1-C6alkyl, C1-C8haloa... | 06/10/2010 |
| 20100130597 | DNA-PKCS MODULATES ENERGY REGULATION AND BRAIN FUNCTION The invention relates to new functions of the DNA-PKcs gene product in energy metabolism, brain function and physical fitness. ... | 05/27/2010 |
| 20100113438 | CLASS OF HISTONE DEACETYLASE INHIBITORS New histone deacetylase inhibitors according to the general formula (I) wherein: Q is a bond, CH2, CH—NR3R4, NR5 or oxygen, X is CH or nitrogen, Y is a bond, CH2, oxygen or NR6, Z is CH or nitrogen, R 05/06/2010 | |
| 20100105672 | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a ther... | 04/29/2010 |
| 20100105671 | C7-fluoro substituted tetracycline compounds The present invention is directed to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (A) are defined herein. Also describe... | 04/29/2010 |
| 20100087415 | INHIBITORS OF STORE OPERATED CALCIUM RELEASE Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other co... | 04/08/2010 |
